Development Level

Tbio 12 | 11,651
Tchem 1 | 1,388

IMPC Phenotype

preweaning lethality, complete... 3 | 979
decreased total body fat amoun... 2 | 207
abnormal embryo size 1 | 220
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased leukocyte cell numbe... 1 | 73
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged spleen 1 | 41
increased bone mineral density 1 | 72
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 9 | 11,493
Kabuki syndrome 8 | 27
ovarian cancer 7 | 8,520
Cancer 6 | 2,499
psoriasis 6 | 6,694
Kidney cancer 5 | 2,613
medulloblastoma, large-cell 5 | 6,241
osteosarcoma 5 | 7,950
Breast cancer 4 | 3,578
atypical teratoid / rhabdoid tumor 4 | 5,112
glioblastoma 4 | 5,792
group 3 medulloblastoma 4 | 4,104
Bladder Neoplasm 3 | 112
Esophageal Squamous Cell Carcinoma 3 | 77
Intellectual disability 3 | 1,016
Liver cancer 3 | 604
Squamous cell carcinoma of esophagus 3 | 77
Urinary Bladder Neoplasms 3 | 114
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
Abnormal dermatoglyphic pattern 2 | 24
Abnormal vertebral bodies 2 | 16
Acquired scoliosis 2 | 281
Adenoid Cystic Carcinoma 2 | 99
Anemia, Hemolytic 2 | 55
Atrial Septal Defects 2 | 85
Autoimmune thrombocytopenia 2 | 22
Birthmark 2 | 35
Blepharoptosis 2 | 231
Blue sclera 2 | 32
Bowed and upward slanting eyebrows 2 | 41
Broad flat nasal bridge 2 | 236
Byzanthine arch palate 2 | 194
Cafe-au-Lait Spots 2 | 37
Carcinoma, Adenoid Cystic 2 | 99
Carcinoma, Hepatocellular 2 | 228
Carcinoma, Transitional Cell 2 | 32
Cerebral atrophy 2 | 178
Conductive hearing loss 2 | 123
Congenital anomaly of spine 2 | 16
Congenital deafness 2 | 185
Congenital hemivertebra 2 | 25
Congenital hypothyroidism 2 | 26
Curvature of spine 2 | 282
DOID:2627 2 | 94
Deafness 2 | 198
Decreased size of teeth 2 | 62
Decreased width of tooth 2 | 59
Dental abnormalities 2 | 60
Depressed nasal tip 2 | 11
Dilated ventricles (finding) 2 | 121
Endometrial cancer 2 | 311
Failure to gain weight 2 | 365
Hearing Loss, Partial 2 | 185
Hip Dislocation, Congenital 2 | 48
Hirsutism 2 | 47
Hypodontia 2 | 81
Idiopathic thrombocytopenia 2 | 22
Immune thrombocytopenic purpura 2 | 24
Joint hyperflexibility 2 | 78
Large auricle 2 | 87
Large dysplastic ears 2 | 87
Large pinnae 2 | 87
Large prominent ears 2 | 87
Large protruding ears 2 | 87
Large, floppy ears 2 | 87
Liver carcinoma 2 | 240
Long eyelashes 2 | 37
Long palpebral fissure 2 | 17
Lymphoid leukemia 2 | 160
Macrotia 2 | 87
Malabsorption 2 | 82
Melanoma 2 | 711
Microdontia (disorder) 2 | 59
Multiple vertebral anomalies 2 | 16
Nasal bridge wide 2 | 236
Obstruction of pelviureteric junction 2 | 8
Pediatric failure to thrive 2 | 365
Posteriorly rotated ear 2 | 61
Postnatal growth retardation 2 | 57
Preauricular Fistulae, Congenital 2 | 27
Preauricular dimple 2 | 27
Preauricular sinus 2 | 27
Prominent ear 2 | 56
Protruding ears 2 | 56
Range of joint movement increased 2 | 32
Recurrent aspiration pneumonia 2 | 4
Recurrent infections 2 | 48
Recurrent otitis media 2 | 42
Seizures 2 | 596
Sensorineural Hearing Loss (disorder) 2 | 284
Sezary Syndrome 2 | 27
Short fifth finger 2 | 9
Sparse eyebrow 2 | 42
Strabismus 2 | 270
Thick, flared eyebrows 2 | 41
Tooth Abnormalities 2 | 69
Ventricular Septal Defects 2 | 119
Widely spaced teeth 2 | 31
hearing impairment 2 | 199

Tissue

Endocrine System 13 | 18,159
Nervous System 13 | 16,725
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678
Blood and immune system 12 | 16,909
Cardiovascular System 12 | 15,192
Digestive Tract 12 | 17,369
Female tissues 12 | 17,400
Liver and Pancreas 12 | 16,750
Male tissues 12 | 17,142
Respiratory system 12 | 16,393

Target Family

Non-IDG 6 | 12,091
Epigenetic 5 | 242
Enzyme 1 | 4,145
Nuclear Receptor 1 | 48

Compartment GO Term

MLL3/4 complex 13 | 13
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nuclear receptor subfamily 2 group E member 1 NR2E1 Tbio Nuclear Receptor -1.67371 50.0 223
WD repeat-containing protein 5 WDR5 Tchem Non-IDG -2.10077 115.4 299
PAX-interacting protein 1 PAXIP1 Tbio Non-IDG -1.63612 44.7 79
Lysine-specific demethylase 6A KDM6A Tbio Epigenetic -2.27999 176.8 119
Histone-lysine N-methyltransferase 2C KMT2C Tbio Epigenetic -1.87625 76.5 68
Histone-lysine N-methyltransferase 2D KMT2D Tbio Epigenetic -2.08086 118.1 133
Histone-lysine N-methyltransferase 2B KMT2B Tbio Epigenetic -1.93899 84.8 153
PAXIP1-associated glutamate-rich protein 1 PAGR1 Tbio Non-IDG -1.03602 8.61 59
Histone-lysine N-methyltransferase SETD1A SETD1A Tbio Epigenetic -2.57679 365.2 125
Retinoblastoma-binding protein 5 RBBP5 Tbio Non-IDG -1.40059 20.2 180