Development Level

Tbio 8 | 11,178
Tchem 5 | 1,885

IMPC Phenotype

preweaning lethality, complete... 3 | 979
decreased total body fat amoun... 2 | 207
abnormal embryo size 1 | 220
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased leukocyte cell numbe... 1 | 73
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged spleen 1 | 41
increased bone mineral density 1 | 72
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 9 | 11,192
Kabuki syndrome 8 | 27
ovarian cancer 7 | 8,297
Cancer 6 | 2,388
psoriasis 6 | 6,514
Kidney cancer 5 | 2,548
medulloblastoma, large-cell 5 | 6,086
osteosarcoma 5 | 7,766
Breast cancer 4 | 3,469
atypical teratoid / rhabdoid tumor 4 | 4,971
glioblastoma 4 | 5,635
group 3 medulloblastoma 4 | 4,002
Bladder Neoplasm 3 | 106
Esophageal Squamous Cell Carcinoma 3 | 72
Intellectual disability 3 | 998
Liver cancer 3 | 589
Squamous cell carcinoma of esophagus 3 | 72
Urinary Bladder Neoplasms 3 | 108
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,872
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,204
Abnormal dermatoglyphic pattern 2 | 24
Abnormal vertebral bodies 2 | 14
Acquired scoliosis 2 | 274
Adenoid Cystic Carcinoma 2 | 90
Anemia, Hemolytic 2 | 55
Atrial Septal Defects 2 | 81
Autoimmune thrombocytopenia 2 | 21
Birthmark 2 | 35
Blepharoptosis 2 | 229
Blue sclera 2 | 32
Bowed and upward slanting eyebrows 2 | 39
Broad flat nasal bridge 2 | 232
Byzanthine arch palate 2 | 194
Cafe-au-Lait Spots 2 | 37
Carcinoma, Adenoid Cystic 2 | 90
Carcinoma, Hepatocellular 2 | 217
Carcinoma, Transitional Cell 2 | 31
Cerebral atrophy 2 | 175
Conductive hearing loss 2 | 122
Congenital anomaly of spine 2 | 14
Congenital deafness 2 | 180
Congenital hemivertebra 2 | 23
Congenital hypothyroidism 2 | 25
Curvature of spine 2 | 275
DOID:2627 2 | 89
Deafness 2 | 193
Decreased size of teeth 2 | 62
Decreased width of tooth 2 | 59
Dental abnormalities 2 | 57
Depressed nasal tip 2 | 11
Dilated ventricles (finding) 2 | 119
Endometrial cancer 2 | 301
Failure to gain weight 2 | 359
Hearing Loss, Partial 2 | 180
Hip Dislocation, Congenital 2 | 46
Hirsutism 2 | 46
Hypodontia 2 | 81
Idiopathic thrombocytopenia 2 | 21
Immune thrombocytopenic purpura 2 | 23
Joint hyperflexibility 2 | 76
Large auricle 2 | 85
Large dysplastic ears 2 | 85
Large pinnae 2 | 85
Large prominent ears 2 | 85
Large protruding ears 2 | 85
Large, floppy ears 2 | 85
Liver carcinoma 2 | 229
Long eyelashes 2 | 36
Long palpebral fissure 2 | 17
Lymphoid leukemia 2 | 156
Macrotia 2 | 85
Malabsorption 2 | 81
Melanoma 2 | 689
Microdontia (disorder) 2 | 59
Multiple vertebral anomalies 2 | 14
Nasal bridge wide 2 | 232
Obstruction of pelviureteric junction 2 | 8
Pediatric failure to thrive 2 | 359
Posteriorly rotated ear 2 | 59
Postnatal growth retardation 2 | 56
Preauricular Fistulae, Congenital 2 | 27
Preauricular dimple 2 | 27
Preauricular sinus 2 | 27
Prominent ear 2 | 55
Protruding ears 2 | 55
Range of joint movement increased 2 | 32
Recurrent aspiration pneumonia 2 | 4
Recurrent infections 2 | 48
Recurrent otitis media 2 | 41
Seizures 2 | 584
Sensorineural Hearing Loss (disorder) 2 | 281
Sezary Syndrome 2 | 27
Short fifth finger 2 | 9
Sparse eyebrow 2 | 40
Strabismus 2 | 265
Thick, flared eyebrows 2 | 39
Tooth Abnormalities 2 | 66
Ventricular Septal Defects 2 | 113
Widely spaced teeth 2 | 31
hearing impairment 2 | 194

Tissue

Endocrine System 13 | 18,159
Nervous System 13 | 16,725
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678
Blood and immune system 12 | 16,909
Cardiovascular System 12 | 15,192
Digestive Tract 12 | 17,369
Female tissues 12 | 17,400
Liver and Pancreas 12 | 16,750
Male tissues 12 | 17,142
Respiratory system 12 | 16,393

Target Family

Non-IDG 6 | 12,091
Epigenetic 5 | 242
Enzyme 1 | 4,145
Nuclear Receptor 1 | 48

Compartment GO Term

MLL3/4 complex 13 | 13
cellular_component 17,863 | 17,863
Cell 15,779 | 15,779
Cell part 15,778 | 15,778
Intracellular 13,764 | 13,764
Intracellular part 13,630 | 13,630
Organelle 11,921 | 11,921
Intracellular organelle 11,712 | 11,712
membrane-bounded organelle 10,823 | 10,823
Cytoplasm 10,720 | 10,720
Intracellular membrane-bounded... 10,057 | 10,057
Cytoplasmic part 9,029 | 9,029
Organelle part 8,755 | 8,755
Intracellular organelle part 8,566 | 8,566
Membrane 8,335 | 8,335
Nucleus 7,336 | 7,336
Cytosol 6,551 | 6,551
Membrane part 6,403 | 6,403
Plasma membrane 5,682 | 5,682
Macromolecular complex 5,345 | 5,345
Intrinsic component of membran... 5,320 | 5,320
Cell periphery 5,248 | 5,248
Integral component of membrane 5,197 | 5,197
Nucleoplasm 4,931 | 4,931
Intracellular organelle lumen 4,923 | 4,923
Organelle lumen 4,923 | 4,923
membrane-enclosed lumen 4,923 | 4,923
Nuclear part 4,169 | 4,169
Endomembrane system 4,108 | 4,108
Intracellular non-membrane-bou... 3,917 | 3,917
non-membrane-bounded organelle 3,917 | 3,917
Nuclear lumen 3,851 | 3,851
Protein complex 3,565 | 3,565
Organelle membrane 2,798 | 2,798
Extracellular region 2,600 | 2,600
Plasma membrane part 2,531 | 2,531
Vesicle 2,280 | 2,280
Cytoplasmic vesicle 2,158 | 2,158
Intracellular vesicle 2,157 | 2,157
Cytoskeleton 2,084 | 2,084
Bounding membrane of organelle 1,924 | 1,924
Endoplasmic reticulum 1,922 | 1,922
Golgi apparatus 1,884 | 1,884
Intrinsic component of plasma ... 1,701 | 1,701
Integral component of plasma m... 1,647 | 1,647
Cytoskeletal part 1,613 | 1,613
Catalytic complex 1,592 | 1,592
Vesicles 1,566 | 1,566
Mitochondrion 1,557 | 1,557
Extracellular region part 1,533 | 1,533
Cell projection 1,524 | 1,524
Whole membrane 1,521 | 1,521
Cytoplasmic vesicle part 1,468 | 1,468
Endoplasmic reticulum part 1,315 | 1,315
GO:0031975 1,139 | 1,139
Organelle envelope 1,131 | 1,131
Microtubule cytoskeleton 1,127 | 1,127
Nucleoplasm part 1,100 | 1,100
Nuclear outer membrane-endopla... 1,094 | 1,094
Endoplasmic reticulum membrane 1,076 | 1,076
Extracellular space 1,059 | 1,059
Mitochondrial part 1,027 | 1,027
Chromosome 1,020 | 1,020
Mitochondria 985 | 985
Neuron part 958 | 958
Supramolecular polymer 950 | 950
Cell junction 949 | 949
Supramolecular complex 949 | 949
Supramolecular fiber 942 | 942
Secretory vesicle 930 | 930
Golgi apparatus part 923 | 923
Nucleoli 923 | 923
Nucleolus 916 | 916
Endosome 915 | 915
Chromosomal part 872 | 872
GO:0098796 868 | 868
Ribonucleoprotein complex 845 | 845
Cell projection part 838 | 838
Transferase complex 837 | 837
Intracellular ribonucleoprotei... 830 | 830
Plasma membrane region 826 | 826
Secretory granule 810 | 810
Cell surface 805 | 805
Vesicle membrane 786 | 786
Cytoplasmic vesicle membrane 780 | 780
Polymeric cytoskeletal fiber 753 | 753
Mitochondrial envelope 739 | 739
Golgi membrane 715 | 715
Microtubule organizing center 712 | 712
Nuclear body 708 | 708
Vacuole 708 | 708
Neuron projection 701 | 701
Mitochondrial membrane 689 | 689
Centrosome 685 | 685
Extracellular matrix 670 | 670
Receptor complex 670 | 670
Synapse 656 | 656
Lysosome 600 | 600
Lytic vacuole 600 | 600
Endosomal part 554 | 554
Chromatin 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Retinoblastoma-binding protein 5 RBBP5 Tchem Non-IDG -1.40059 20.2 180
Set1/Ash2 histone methyltransferase complex subunit ASH2 ASH2L Tbio Enzyme -1.56543 33.7 261
Nuclear receptor coactivator 6 NCOA6 Tbio Non-IDG -1.83369 72.1 54
Protein dpy-30 homolog DPY30 Tbio Non-IDG -1.33225 21.6 34
Histone-lysine N-methyltransferase SETD1A SETD1A Tbio Epigenetic -2.57679 365.2 125
Histone-lysine N-methyltransferase 2B KMT2B Tbio Epigenetic -1.93899 84.8 153
Lysine-specific demethylase 6A KDM6A Tchem Epigenetic -2.27999 176.8 119
Histone-lysine N-methyltransferase 2C KMT2C Tchem Epigenetic -1.87625 76.5 68
Histone-lysine N-methyltransferase 2D KMT2D Tbio Epigenetic -2.08086 118.1 133
PAXIP1-associated glutamate-rich protein 1 PAGR1 Tbio Non-IDG -1.03602 8.61 59