Development Level

Tbio 33 | 11,445
Tchem 7 | 1,598
Tdark 4 | 6,588

IMPC Phenotype

preweaning lethality, complete... 10 | 979
embryonic lethality prior to o... 3 | 239
decreased bone mineral density 2 | 126
decreased total body fat amoun... 2 | 207
increased lean body mass 2 | 172
abnormal behavior 1 | 298
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal pericardium morpholog... 1 | 26
abnormal retinal outer nuclear... 1 | 3
cataract 1 | 92
corneal opacity 1 | 32
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased startle reflex 1 | 75
decreased total retina thickne... 1 | 17
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
enlarged spleen 1 | 41
impaired pupillary reflex 1 | 26
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased total body fat amoun... 1 | 134
irregularly shaped pupil 1 | 7
mydriasis 1 | 6
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 35 | 11,493
ovarian cancer 21 | 8,520
osteosarcoma 18 | 7,950
Cancer 14 | 2,499
psoriasis 14 | 6,694
group 3 medulloblastoma 13 | 4,104
Kidney cancer 12 | 2,613
glioblastoma 11 | 5,792
malignant mesothelioma 11 | 3,232
medulloblastoma, large-cell 11 | 6,241
Intellectual disability 10 | 1,016
atypical teratoid / rhabdoid tumor 9 | 5,112
lung cancer 9 | 4,740
Breast cancer 8 | 3,578
Liver cancer 7 | 604
adult high grade glioma 7 | 3,801
Kabuki syndrome 6 | 27
colon cancer 6 | 1,478
ependymoma 6 | 4,679
pancreatic cancer 6 | 2,398
spina bifida 6 | 1,074
Leukemia 5 | 104
Pick disease 5 | 1,894
acute quadriplegic myopathy 5 | 1,158
astrocytic glioma 5 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
invasive ductal carcinoma 5 | 2,951
Bladder Neoplasm 4 | 112
Dull intelligence 4 | 645
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Muscle hypotonia 4 | 571
Neurodevelopmental Disorders 4 | 70
Poor school performance 4 | 645
Rheumatoid arthritis 4 | 1,191
Urinary Bladder Neoplasms 4 | 114
juvenile dermatomyositis 4 | 1,187
oligodendroglioma 4 | 2,850
primitive neuroectodermal tumor 4 | 3,035
subependymal giant cell astrocytoma 4 | 2,287
Adenocarcinoma 3 | 122
Adenoid Cystic Carcinoma 3 | 99
Carcinoma, Adenoid Cystic 3 | 99
Carcinoma, Hepatocellular 3 | 228
Endometrial cancer 3 | 311
Failure to gain weight 3 | 365
Leukemia, Myelocytic, Acute 3 | 120
Leukemia, Myeloid, Acute 3 | 105
Liver carcinoma 3 | 240
Lymphoid leukemia 3 | 160
Multiple myeloma 3 | 1,332
Parkinson's disease 3 | 392
Pediatric failure to thrive 3 | 365
Schizophrenia 3 | 1,160
Short stature 3 | 531
cutaneous lupus erythematosus 3 | 1,057
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung adenocarcinoma 3 | 2,716
non primary Sjogren syndrome sicca 3 | 891
non-small cell lung cancer 3 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pediatric high grade glioma 3 | 1,064
Amyotrophic lateral sclerosis 2 | 451
Atopic dermatitis 2 | 952
Autism spectrum disorder 2 | 101
Breast Neoplasms 2 | 445
Broad flat nasal bridge 2 | 236
Byzanthine arch palate 2 | 194
Carcinoma, Transitional Cell 2 | 32
Conductive hearing loss 2 | 123
DOID:2627 2 | 94
Dystonia 2 | 164
Epilepsy 2 | 792
Immune system cancer 2 | 140
Large intestine cancer 2 | 126
Leukemia, Myeloid 2 | 18
Liver neoplasms 2 | 130
Mammary Neoplasms 2 | 425
Melanoma 2 | 711
Myeloid Leukemia 2 | 19
Nasal bridge wide 2 | 236
Seizures 2 | 596
Sensorineural Hearing Loss (disorder) 2 | 284
Skin cancer 2 | 469
Stomach Neoplasms 2 | 300
Strabismus 2 | 270
Tremor 2 | 113
acute myeloid leukemia 2 | 783
adrenocortical carcinoma 2 | 1,428
aldosterone-producing adenoma 2 | 665
astrocytoma 2 | 1,146
breast carcinoma 2 | 1,638
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
esophageal adenocarcinoma 2 | 737
interstitial cystitis 2 | 2,312
sonic hedgehog group medulloblastoma 2 | 467

Tissue

Blood and immune system 44 | 16,909
Digestive Tract 44 | 17,369
Endocrine System 44 | 18,159
Female tissues 44 | 17,400
Liver and Pancreas 44 | 16,750
Male tissues 44 | 17,142
Respiratory system 44 | 16,393
Skin and soft tissues 44 | 17,230
Urinary Tract 44 | 16,678
Cardiovascular System 43 | 15,192
Nervous System 43 | 16,725

Target Family

Non-IDG 19 | 12,091
Epigenetic 12 | 242
Transcription Factor 7 | 1,400
Enzyme 4 | 4,145
Kinase 2 | 634

Compartment GO Term

MLL1 complex 44 | 44
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ribosomal biogenesis protein LAS1L LAS1L Tdark Non-IDG -0.48801 2.91 109
Adenylate kinase isoenzyme 6 AK6 Tbio Kinase -2.18859 223.1 91
Histone-lysine N-methyltransferase SETD1A SETD1A Tbio Epigenetic -2.57679 365.2 125
MAX gene-associated protein MGA Tbio Transcription Factor -0.85532 6.90 42
Histone-lysine N-methyltransferase 2B KMT2B Tbio Epigenetic -1.93899 84.8 153
Transcription initiation factor TFIID subunit 6 TAF6 Tbio Non-IDG -1.10650 12.8 159
Histone-lysine N-methyltransferase SETD1B SETD1B Tbio Epigenetic -1.30968 18.7 90
Transcription initiation factor TFIID subunit 7 TAF7 Tbio Non-IDG -1.16026 13.4 138
Homeobox protein Hox-A10 HOXA10 Tbio Transcription Factor -2.31212 210.6 170
Homeobox protein Hox-A6 HOXA6 Tbio Transcription Factor -1.01815 9.41 183