Development Level

Tbio 17 | 11,445
Tchem 5 | 1,598

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal embryo size 1 | 220
abnormal placenta morphology 1 | 5
abnormal placenta size 1 | 20
abnormal placenta vasculature 1 | 2
abnormal tail morphology 1 | 25
abnormal testis morphology 1 | 43
cataract 1 | 92
decreased circulating glucose ... 1 | 126
decreased heart left ventricle... 1 | 28
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased circulating glucose ... 1 | 24
increased fasted circulating g... 1 | 76
prenatal lethality prior to he... 1 | 87
small testis 1 | 58
syndactyly 1 | 23

Disease

Carcinoma 17 | 11,493
Breast cancer 16 | 3,578
psoriasis 16 | 6,694
glioblastoma 15 | 5,792
medulloblastoma, large-cell 15 | 6,241
ovarian cancer 15 | 8,520
Cancer 14 | 2,499
lung cancer 14 | 4,740
osteosarcoma 14 | 7,950
adrenocortical carcinoma 13 | 1,428
atypical teratoid / rhabdoid tumor 13 | 5,112
group 3 medulloblastoma 13 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
invasive ductal carcinoma 13 | 2,951
primitive neuroectodermal tumor 13 | 3,035
Atopic dermatitis 10 | 952
ependymoma 10 | 4,679
lung adenocarcinoma 10 | 2,716
nasopharyngeal carcinoma 10 | 1,058
non-small cell lung cancer 10 | 2,890
pancreatic cancer 10 | 2,398
Endometriosis 9 | 540
adult high grade glioma 9 | 3,801
ductal carcinoma in situ 9 | 1,745
malignant mesothelioma 9 | 3,232
breast carcinoma 8 | 1,638
colon cancer 8 | 1,478
Intellectual disability 6 | 1,016
Dull intelligence 5 | 645
Kidney cancer 5 | 2,613
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Poor school performance 5 | 645
Short stature 5 | 531
Small head 5 | 374
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
pediatric high grade glioma 5 | 1,064
ulcerative colitis 5 | 1,819
Astrocytoma, Pilocytic 4 | 3,081
Cognitive delay 4 | 608
Glaucoma 4 | 239
Global developmental delay 4 | 608
Hypoplastic mandible condyle 4 | 275
Mandibular hypoplasia 4 | 275
Mental and motor retardation 4 | 608
Micrognathism 4 | 275
Multiple myeloma 4 | 1,332
Prostatic Neoplasms 4 | 495
esophageal adenocarcinoma 4 | 737
interstitial cystitis 4 | 2,312
oligodendroglioma 4 | 2,850
primary Sjogren syndrome 4 | 735
Abnormality of vision 3 | 40
Abnormally small eyeball 3 | 97
Ascites 3 | 22
Cataract 3 | 297
Cerebellar Hypoplasia 3 | 61
Cleft Palate 3 | 271
Clouding of corneal stroma 3 | 50
Congenital Epicanthus 3 | 177
Corneal Opacity 3 | 53
Dandy-Walker Syndrome 3 | 39
Decreased size of eyeball 3 | 97
Fetal Growth Retardation 3 | 189
Increased nuchal translucency 3 | 6
Infant, Small for Gestational Age 3 | 176
Intrauterine retardation 3 | 176
Lens Opacities 3 | 231
MOSAIC VARIEGATED ANEUPLOIDY SYNDROME 3 | 5
Microcephaly 3 | 166
Microphthalmos 3 | 100
Muscle biopsy shows dystrophic changes 3 | 39
Muscular dystrophy 3 | 75
Pick disease 3 | 1,894
Polyhydramnios 3 | 108
Prostate cancer 3 | 175
Stomach Neoplasms 3 | 300
Triangular face 3 | 58
acute quadriplegic myopathy 3 | 1,158
astrocytic glioma 3 | 2,597
mosaic variegated aneuploidy syndrome 1 3 | 4
pancreatic carcinoma 3 | 562
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
Adenoma 2 | 167
Multiple Sclerosis 2 | 540
Neuroblastoma 2 | 80
Pancreatic Neoplasm 2 | 85
Pancreatic Neoplasms 2 | 85
Polycystic ovary syndrome 2 | 360
Waldenstrons macroglobulinemia 2 | 765
active Crohn's disease 2 | 922
acute myeloid leukemia 2 | 783
astrocytoma 2 | 1,146
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
pituitary cancer 2 | 1,972
spina bifida 2 | 1,074
subependymal giant cell astrocytoma 2 | 2,287

Tissue

Blood and immune system 22 | 16,909
Digestive Tract 22 | 17,369
Endocrine System 22 | 18,159
Female tissues 21 | 17,400
Liver and Pancreas 21 | 16,750
Male tissues 21 | 17,142
Nervous System 21 | 16,725
Respiratory system 21 | 16,393
Skin and soft tissues 21 | 17,230
Urinary Tract 21 | 16,678
Cardiovascular System 20 | 15,192

Target Family

Non-IDG 11 | 12,091
Transcription Factor 6 | 1,400
Kinase 4 | 634
Enzyme 1 | 4,145

Compartment GO Term

MAD1 complex 22 | 22
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mitotic spindle assembly checkpoint protein MAD1 MAD1L1 Tbio Non-IDG -1.17500 13.6 283
Nucleoprotein TPR TPR Tbio Non-IDG -2.11491 135.6 161
Max-interacting protein 1 MXI1 Tbio Transcription Factor -2.03408 107.7 179
Paired amphipathic helix protein Sin3b SIN3B Tbio Non-IDG -1.34131 21.4 148
Kinetochore scaffold 1 KNL1 Tbio Non-IDG -2.20924 151.8 85
Centromere-associated protein E CENPE Tchem Non-IDG -2.14817 140.2 166
Dual specificity protein kinase TTK TTK Tchem Kinase -2.33639 219.1 336
Telomerase reverse transcriptase TERT Tchem Enzyme -3.56910 3506.4 643
Max dimerization protein 4 MXD4 Tbio Transcription Factor -1.54512 32.6 122
Max-binding protein MNT MNT Tbio Transcription Factor -2.72910 534.1 103