Development Level

Tbio 190 | 11,651
Tdark 34 | 6,593
Tchem 27 | 1,388
Tclin 6 | 612

Collection

GPCR: IDG Consortium (Targets) 1 | 126
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 19 | 979
abnormal behavior 9 | 298
embryonic lethality prior to t... 8 | 278
preweaning lethality, incomple... 8 | 499
increased lean body mass 7 | 172
decreased body weight 6 | 161
decreased total body fat amoun... 6 | 207
embryonic lethality prior to o... 6 | 239
increased circulating alkaline... 6 | 122
abnormal bone structure 5 | 187
abnormal embryo size 5 | 220
edema 5 | 59
increased bone mineral content 5 | 108
increased bone mineral density 5 | 72
increased circulating sodium l... 5 | 71
abnormal heart morphology 4 | 162
hypoactivity 4 | 132
increased mean corpuscular hem... 4 | 96
short tibia 4 | 97
abnormal bone mineralization 3 | 38
abnormal craniofacial morpholo... 3 | 33
abnormal iris morphology 3 | 13
abnormal pericardium morpholog... 3 | 26
abnormal seminal vesicle morph... 3 | 114
absent pinna reflex 3 | 23
decreased mean corpuscular hem... 3 | 50
decreased vertical activity 3 | 208
enlarged lymph nodes 3 | 37
hemorrhage 3 | 23
increased blood urea nitrogen ... 3 | 48
increased circulating potassiu... 3 | 29
increased circulating triglyce... 3 | 42
increased mean corpuscular vol... 3 | 92
increased startle reflex 3 | 112
increased total body fat amoun... 3 | 134
prolonged QT interval 3 | 38
prolonged ST segment 3 | 36
abnormal behavioral response t... 2 | 66
abnormal cecum morphology 2 | 7
abnormal coat-hair pigmentatio... 2 | 64
abnormal eye morphology 2 | 68
abnormal eye size 2 | 7
abnormal head size 2 | 6
abnormal locomotor activation 2 | 16
abnormal neural tube closure 2 | 46
abnormal response to new envir... 2 | 10
abnormal skin coloration 2 | 25
cardiovascular system phenotyp... 2 | 36
decreased bone mineral density 2 | 126
decreased circulating HDL chol... 2 | 68
decreased circulating calcium ... 2 | 36
decreased circulating insulin ... 2 | 76
decreased circulating serum al... 2 | 82
decreased erythrocyte cell num... 2 | 62
decreased lean body mass 2 | 135
decreased mean corpuscular vol... 2 | 79
decreased prepulse inhibition 2 | 82
enlarged cecum 2 | 5
enlarged heart 2 | 210
hyperactivity 2 | 148
impaired glucose tolerance 2 | 75
improved glucose tolerance 2 | 79
increased body weight 2 | 25
increased circulating HDL chol... 2 | 80
increased circulating creatini... 2 | 38
increased circulating fructosa... 2 | 13
increased circulating iron lev... 2 | 30
increased circulating total pr... 2 | 28
narrow eye opening 2 | 12
polycystic kidney 2 | 15
prenatal lethality 2 | 28
prenatal lethality prior to he... 2 | 87
small adrenal glands 2 | 16
thrombocytosis 2 | 27
tremors 2 | 39
trunk curl 2 | 16
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal ear morphology 1 | 9
abnormal lens morphology 1 | 81
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 71
abnormal tail movements 1 | 12
abnormal vertebrae morphology 1 | 18
abnormal vocalization 1 | 21
abnormal whole-body plethysmog... 1 | 4
convulsive seizures 1 | 13
decreased T cell number 1 | 15
decreased circulating amylase ... 1 | 28
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
enlarged urinary bladder 1 | 8
increased anti-nuclear antigen... 1 | 19
increased body length 1 | 32
increased circulating amylase ... 1 | 25
increased circulating choleste... 1 | 66
increased circulating magnesiu... 1 | 10
increased circulating phosphat... 1 | 26
persistence of hyaloid vascula... 1 | 33

Disease

ovarian cancer 160 | 8,520
Carcinoma 151 | 11,493
osteosarcoma 127 | 7,950
glioblastoma 103 | 5,792
medulloblastoma, large-cell 98 | 6,241
psoriasis 76 | 6,694
atypical teratoid / rhabdoid tumor 73 | 5,112
lung cancer 71 | 4,740
lung carcinoma 67 | 2,843
ependymoma 65 | 4,679
adult high grade glioma 56 | 3,801
invasive ductal carcinoma 55 | 2,951
Astrocytoma, Pilocytic 54 | 3,081
malignant mesothelioma 53 | 3,232
tuberculosis 52 | 2,010
Breast cancer 51 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 50 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 49 | 2,989
pancreatic cancer 49 | 2,398
intraductal papillary-mucinous adenoma (IPMA) 47 | 2,955
subependymal giant cell astrocytoma 46 | 2,287
group 3 medulloblastoma 45 | 4,104
pancreatic ductal adenocarcinoma liver metastasis 44 | 1,962
non-small cell lung cancer 42 | 2,890
Cancer 40 | 2,499
interstitial cystitis 39 | 2,312
lung adenocarcinoma 38 | 2,716
diabetes mellitus 37 | 1,728
astrocytoma 36 | 1,146
Multiple myeloma 35 | 1,332
breast carcinoma 35 | 1,638
Autosomal recessive predisposition 33 | 1,442
Kidney cancer 33 | 2,613
acute quadriplegic myopathy 33 | 1,158
oligodendroglioma 33 | 2,850
Pick disease 32 | 1,894
Rheumatoid arthritis 31 | 1,191
astrocytic glioma 31 | 2,597
juvenile dermatomyositis 31 | 1,187
primitive neuroectodermal tumor 31 | 3,035
active Crohn's disease 30 | 922
dermatomyositis 28 | 966
ulcerative colitis 28 | 1,819
adrenocortical carcinoma 26 | 1,428
ductal carcinoma in situ 26 | 1,745
group 4 medulloblastoma 26 | 1,855
pediatric high grade glioma 26 | 1,064
pituitary cancer 26 | 1,972
primary pancreatic ductal adenocarcinoma 26 | 1,109
cutaneous lupus erythematosus 25 | 1,057
cystic fibrosis 25 | 1,696
esophageal adenocarcinoma 23 | 737
Alzheimer's disease 21 | 658
primary Sjogren syndrome 21 | 735
Muscle hypotonia 20 | 571
Waldenstrons macroglobulinemia 20 | 765
active ulcerative colitis 19 | 764
mucosa-associated lymphoid tissue lymphoma 19 | 484
Down syndrome 18 | 499
Intellectual disability 18 | 1,016
Multiple Sclerosis 18 | 540
Duchenne muscular dystrophy 17 | 601
Liver Cirrhosis, Experimental 17 | 769
colon cancer 17 | 1,478
Epilepsy 16 | 792
Neurodegenerative disease 16 | 414
Cognitive delay 15 | 608
Global developmental delay 15 | 608
Mental and motor retardation 15 | 608
Schizophrenia 15 | 1,160
gastric carcinoma 15 | 807
spina bifida 15 | 1,074
Dull intelligence 14 | 645
Low intelligence 14 | 645
Mental Retardation 14 | 645
Mental deficiency 14 | 645
Poor school performance 14 | 645
non primary Sjogren syndrome sicca 13 | 891
head and neck cancer and chronic obstructive pulmonary disease 12 | 239
pancreatic carcinoma 12 | 562
posterior fossa group A ependymoma 12 | 468
progressive supranuclear palsy 12 | 676
sarcoidosis 12 | 370
Melanoma 11 | 711
Seizures 11 | 596
Splenomegaly 11 | 190
medulloblastoma 11 | 720
Hepatomegaly 10 | 285
Hermansky-Pudlak syndrome 10 | 42
Systemic lupus erythematosus 10 | 194
aldosterone-producing adenoma 10 | 665
limb girdle muscular dystrophy 2A 10 | 213
nasopharyngeal carcinoma 10 | 1,058
Anemia 9 | 365
Atopic dermatitis 9 | 952
Cerebellar Ataxia 9 | 304
Hypersensitivity reaction type II disease 9 | 253
Parkinson's disease 9 | 392
Proteinuria 9 | 144
hepatocellular carcinoma 9 | 547

Tissue

Blood and immune system 250 | 16,909
Endocrine System 250 | 18,159
Skin and soft tissues 250 | 17,230
Digestive Tract 249 | 17,369
Female tissues 249 | 17,400
Respiratory system 249 | 16,393
Liver and Pancreas 247 | 16,750
Male tissues 247 | 17,142
Urinary Tract 246 | 16,678
Nervous System 244 | 16,725
Cardiovascular System 239 | 15,192

Target Family

Non-IDG 164 | 12,091
Enzyme 57 | 4,145
Transporter 21 | 473
Ion Channel 8 | 344
GPCR 3 | 408
Transcription Factor 3 | 1,400
Kinase 1 | 634

Compartment GO Term

Lytic vacuole membrane 257 | 257
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
UPF0577 protein KIAA1324 KIAA1324 Tbio Non-IDG -1.30268 19.8 137
Sialin SLC17A5 Tbio Transporter -2.93541 845.6 63
Sphingosine kinase 2 SPHK2 Tchem Kinase -2.21878 154.9 314
Vesicle-associated membrane protein 8 VAMP8 Tbio Non-IDG -1.79654 64.6 107
AP-1 complex subunit mu-2 AP1M2 Tbio Non-IDG -2.54240 341.5 68
KICSTOR complex protein kaptin KPTN Tbio Non-IDG -1.45875 26.8 153
Cell cycle control protein 50A TMEM30A Tbio Non-IDG -1.11992 12.5 36
Lipopolysaccharide-induced tumor necrosis factor-alpha factor LITAF Tbio Transcription Factor -2.03585 113.9 202
AP-2 complex subunit sigma AP2S1 Tbio Non-IDG -1.42073 25.5 108
AP-2 complex subunit beta AP2B1 Tbio Non-IDG -1.59767 34.8 212