Development Level

Tbio 439 | 11,445
Tchem 101 | 1,598
Tdark 49 | 6,588
Tclin 35 | 613

Collection

GPCR: IDG Consortium (Targets) 1 | 126
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 43 | 979
preweaning lethality, incomple... 16 | 499
abnormal behavior 13 | 298
embryonic lethality prior to t... 13 | 278
embryonic lethality prior to o... 11 | 239
increased circulating alkaline... 10 | 122
abnormal seminal vesicle morph... 9 | 114
decreased total body fat amoun... 9 | 207
increased lean body mass 9 | 172
abnormal embryo size 8 | 220
abnormal heart morphology 8 | 162
decreased vertical activity 8 | 208
short tibia 8 | 97
abnormal bone structure 7 | 187
decreased body weight 7 | 161
edema 7 | 59
enlarged heart 7 | 210
hypoactivity 7 | 132
increased bone mineral content 7 | 108
increased circulating sodium l... 7 | 71
increased mean corpuscular hem... 7 | 96
abnormal coat-hair pigmentatio... 6 | 64
abnormal retina morphology 6 | 71
decreased circulating serum al... 6 | 82
increased bone mineral density 6 | 72
abnormal craniofacial morpholo... 5 | 33
decreased circulating glucose ... 5 | 126
decreased mean corpuscular hem... 5 | 50
increased blood urea nitrogen ... 5 | 48
increased circulating potassiu... 5 | 29
increased circulating triglyce... 5 | 42
increased mean corpuscular vol... 5 | 92
small adrenal glands 5 | 16
small superior vagus ganglion 5 | 74
abnormal iris morphology 4 | 13
cataract 4 | 92
decreased circulating HDL chol... 4 | 68
decreased leukocyte cell numbe... 4 | 73
decreased prepulse inhibition 4 | 82
enlarged lymph nodes 4 | 37
hyperactivity 4 | 148
impaired glucose tolerance 4 | 75
improved glucose tolerance 4 | 79
increased startle reflex 4 | 112
increased total body fat amoun... 4 | 134
prenatal lethality 4 | 28
prolonged ST segment 4 | 36
thrombocytosis 4 | 27
abnormal body wall morphology 3 | 9
abnormal bone mineralization 3 | 38
abnormal coat appearance 3 | 31
abnormal limb bud morphology 3 | 17
abnormal limb morphology 3 | 13
abnormal pericardium morpholog... 3 | 26
absent pinna reflex 3 | 23
anophthalmia 3 | 33
decreased bone mineral density 3 | 126
decreased circulating bilirubi... 3 | 19
decreased circulating calcium ... 3 | 36
decreased circulating choleste... 3 | 93
decreased circulating insulin ... 3 | 76
decreased circulating triglyce... 3 | 79
decreased erythrocyte cell num... 3 | 62
decreased grip strength 3 | 116
decreased heart weight 3 | 27
embryonic growth retardation 3 | 106
hemorrhage 3 | 23
increased circulating bilirubi... 3 | 16
increased circulating creatini... 3 | 38
increased circulating total pr... 3 | 28
increased grip strength 3 | 41
increased mean corpuscular hem... 3 | 36
increased neutrophil cell numb... 3 | 46
prolonged QT interval 3 | 38
abnormal behavioral response t... 2 | 66
abnormal lens morphology 2 | 81
abnormal neural tube closure 2 | 46
abnormal skin coloration 2 | 25
abnormal sleep behavior 2 | 70
abnormal vibrissa morphology 2 | 25
cardiovascular system phenotyp... 2 | 36
decreased circulating amylase ... 2 | 28
decreased circulating creatini... 2 | 39
decreased circulating sodium l... 2 | 22
decreased lean body mass 2 | 135
decreased red blood cell distr... 2 | 41
increased body length 2 | 32
increased body weight 2 | 25
increased circulating HDL chol... 2 | 80
increased circulating amylase ... 2 | 25
increased circulating calcium ... 2 | 34
increased circulating choleste... 2 | 66
increased circulating fructosa... 2 | 13
increased circulating iron lev... 2 | 30
increased circulating magnesiu... 2 | 10
increased circulating phosphat... 2 | 26
increased circulating serum al... 2 | 22
persistence of hyaloid vascula... 2 | 33
prenatal lethality prior to he... 2 | 87
tremors 2 | 39

Disease

Carcinoma 381 | 11,493
ovarian cancer 359 | 8,520
osteosarcoma 315 | 7,950
psoriasis 239 | 6,694
glioblastoma 236 | 5,792
medulloblastoma, large-cell 235 | 6,241
lung cancer 200 | 4,740
atypical teratoid / rhabdoid tumor 172 | 5,112
ependymoma 159 | 4,679
Cancer 157 | 2,499
malignant mesothelioma 150 | 3,232
lung carcinoma 142 | 2,843
invasive ductal carcinoma 140 | 2,951
Astrocytoma, Pilocytic 137 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 133 | 3,291
Breast cancer 132 | 3,578
tuberculosis 130 | 2,010
intraductal papillary-mucinous adenoma (IPMA) 129 | 2,955
diabetes mellitus 125 | 1,728
non-small cell lung cancer 125 | 2,890
adult high grade glioma 122 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 119 | 2,989
pancreatic cancer 115 | 2,398
Autosomal recessive predisposition 114 | 1,442
lung adenocarcinoma 110 | 2,716
subependymal giant cell astrocytoma 110 | 2,287
group 3 medulloblastoma 108 | 4,104
interstitial cystitis 105 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 97 | 1,962
oligodendroglioma 96 | 2,850
ulcerative colitis 93 | 1,819
primitive neuroectodermal tumor 87 | 3,035
Multiple myeloma 86 | 1,332
Kidney cancer 83 | 2,613
Pick disease 82 | 1,894
breast carcinoma 78 | 1,638
astrocytic glioma 77 | 2,597
ductal carcinoma in situ 74 | 1,745
Rheumatoid arthritis 73 | 1,191
cutaneous lupus erythematosus 73 | 1,057
cystic fibrosis 72 | 1,696
group 4 medulloblastoma 72 | 1,855
astrocytoma 71 | 1,146
acute quadriplegic myopathy 69 | 1,158
dermatomyositis 69 | 966
juvenile dermatomyositis 68 | 1,187
pituitary cancer 68 | 1,972
Waldenstrons macroglobulinemia 65 | 765
Schizophrenia 63 | 1,160
primary pancreatic ductal adenocarcinoma 62 | 1,109
Epilepsy 61 | 792
adrenocortical carcinoma 60 | 1,428
Alzheimer's disease 59 | 658
esophageal adenocarcinoma 59 | 737
Neurodegenerative disease 58 | 414
Intellectual disability 55 | 1,016
Seizures 55 | 596
colon cancer 55 | 1,478
pediatric high grade glioma 53 | 1,064
Liver Cirrhosis, Experimental 50 | 769
Hepatomegaly 48 | 285
active Crohn's disease 48 | 922
Kidney disease 47 | 430
Dull intelligence 46 | 645
Low intelligence 46 | 645
Mental Retardation 46 | 645
Mental deficiency 46 | 645
Poor school performance 46 | 645
Atopic dermatitis 45 | 952
Duchenne muscular dystrophy 45 | 601
primary Sjogren syndrome 45 | 735
Muscle hypotonia 43 | 571
Anemia 42 | 365
Multiple Sclerosis 42 | 540
Dementia 41 | 175
Splenomegaly 41 | 190
gastric carcinoma 41 | 807
Cognitive delay 40 | 608
Global developmental delay 40 | 608
Mental and motor retardation 40 | 608
active ulcerative colitis 40 | 764
mucosa-associated lymphoid tissue lymphoma 39 | 484
spina bifida 39 | 1,074
Arthritis 38 | 290
Obesity 38 | 678
Bipolar Disorder 37 | 666
Down syndrome 37 | 499
Vascular disease 36 | 319
nasopharyngeal carcinoma 35 | 1,058
non primary Sjogren syndrome sicca 35 | 891
Hypersensitivity reaction type II disease 34 | 253
Hypertension 34 | 396
Asthma 32 | 385
Atherosclerosis 32 | 291
Cerebellar Ataxia 32 | 304
Melanoma 32 | 711
Heart disease 31 | 306
Liver disease 31 | 237
pancreatic carcinoma 31 | 562
nephrosclerosis 30 | 333

Tissue

Endocrine System 606 | 18,159
Digestive Tract 604 | 17,369
Female tissues 604 | 17,400
Skin and soft tissues 604 | 17,230
Blood and immune system 600 | 16,909
Liver and Pancreas 600 | 16,750
Urinary Tract 597 | 16,678
Male tissues 595 | 17,142
Respiratory system 594 | 16,393
Nervous System 585 | 16,725
Cardiovascular System 571 | 15,192

Target Family

Non-IDG 369 | 12,091
Enzyme 192 | 4,145
Transporter 24 | 473
Kinase 16 | 634
Ion Channel 11 | 344
GPCR 7 | 408
Transcription Factor 5 | 1,400

Compartment GO Term

Lytic vacuole 624 | 624
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-1,4-galactosyltransferase 1 B4GALT1 Tbio Enzyme -2.34454 211.1 130
Heme-binding protein 2 HEBP2 Tbio Non-IDG -1.05941 10.8 114
CKLF-like MARVEL transmembrane domain-containing protein 6 CMTM6 Tdark Non-IDG -0.56950 2.80 85
Carboxypeptidase Q CPQ Tbio Enzyme -2.51783 330.9 81
Ceroid-lipofuscinosis neuronal protein 6 CLN6 Tbio Non-IDG -1.87357 0.00000 103
Sorting nexin-14 SNX14 Tbio Non-IDG -0.86091 6.82 56
L-amino-acid oxidase IL4I1 Tbio Enzyme -2.79074 622.3 53
Huntingtin HTT Tchem Non-IDG -3.36282 2294.8 599
GATOR complex protein MIOS MIOS Tdark Non-IDG -1.44864 28.1 21
Neuronal vesicle trafficking-associated protein 1 NSG1 Tbio Non-IDG -1.15265 16.1 182