Development Level

Tbio 381 | 10,625
Tchem 109 | 1,890
Tdark 53 | 7,003
Tclin 28 | 602

Collection

Eligible Ion Channel Proteins 1 | 117
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

preweaning lethality, complete... 27 | 633
abnormal behavior 12 | 226
decreased total body fat amoun... 12 | 186
embryonic lethality prior to t... 12 | 187
preweaning lethality, incomple... 10 | 260
decreased body weight 8 | 174
embryonic lethality prior to o... 8 | 148
increased bone mineral content 8 | 92
increased circulating alkaline... 8 | 119
decreased mean corpuscular vol... 7 | 50
increased mean corpuscular hem... 7 | 93
short tibia 7 | 82
decreased body length 6 | 108
decreased circulating glucose ... 6 | 121
decreased circulating serum al... 6 | 79
decreased grip strength 6 | 123
decreased prepulse inhibition 6 | 52
hypoactivity 6 | 89
increased bone mineral density 6 | 52
increased lean body mass 6 | 107
abnormal bone structure 5 | 131
abnormal retina morphology 5 | 100
abnormal retinal pigmentation 5 | 61
abnormal seminal vesicle morph... 5 | 47
abnormal sleep behavior 5 | 63
decreased bone mineral density 5 | 126
decreased circulating HDL chol... 5 | 77
decreased circulating triglyce... 5 | 83
decreased erythrocyte cell num... 5 | 43
decreased mean corpuscular hem... 5 | 34
improved glucose tolerance 5 | 56
increased blood urea nitrogen ... 5 | 44
increased circulating potassiu... 5 | 31
increased circulating sodium l... 5 | 71
increased mean corpuscular vol... 5 | 91
increased or absent threshold ... 5 | 128
small adrenal glands 5 | 15
thrombocytosis 5 | 23
abnormal bone mineralization 4 | 55
abnormal coat/hair pigmentatio... 4 | 54
decreased B cell number 4 | 30
decreased hemoglobin content 4 | 53
decreased lean body mass 4 | 195
decreased leukocyte cell numbe... 4 | 54
decreased rib number 4 | 59
enlarged heart 4 | 111
impaired glucose tolerance 4 | 52
increased circulating choleste... 4 | 53
abnormal embryo size 3 | 112
abnormal epididymis morphology 3 | 31
abnormal iris morphology 3 | 12
abnormal skin morphology 3 | 23
absent pinna reflex 3 | 21
cardiovascular system phenotyp... 3 | 35
decreased CD8-positive, alpha-... 3 | 26
decreased bone mineral content 3 | 157
decreased circulating bilirubi... 3 | 14
decreased circulating choleste... 3 | 85
decreased circulating insulin ... 3 | 75
decreased circulating phosphat... 3 | 15
decreased eosinophil cell numb... 3 | 41
decreased heart weight 3 | 44
decreased lumbar vertebrae num... 3 | 62
decreased monocyte cell number 3 | 28
enlarged lymph nodes 3 | 27
increased B cell number 3 | 23
increased NK cell number 3 | 19
increased circulating HDL chol... 3 | 63
increased circulating LDL chol... 3 | 15
increased effector memory CD8-... 3 | 14
increased fasted circulating g... 3 | 68
increased grip strength 3 | 83
increased leukocyte cell numbe... 3 | 37
increased sacral vertebrae num... 3 | 62
abnormal coat appearance 2 | 25
abnormal coping response 2 | 12
abnormal heart morphology 2 | 51
abnormal kidney morphology 2 | 30
abnormal lung morphology 2 | 15
abnormal rib morphology 2 | 28
abnormal testis morphology 2 | 30
abnormal vibrissa morphology 2 | 17
decreased CD4-positive, alpha ... 2 | 19
decreased T cell number 2 | 31
decreased blood urea nitrogen ... 2 | 31
decreased caudal vertebrae num... 2 | 49
decreased circulating calcium ... 2 | 33
decreased circulating iron lev... 2 | 25
decreased circulating sodium l... 2 | 18
decreased neutrophil cell numb... 2 | 37
enlarged spleen 2 | 26
increased NK T cell number 2 | 11
increased circulating bilirubi... 2 | 16
increased circulating calcium ... 2 | 32
increased circulating chloride... 2 | 43
increased circulating serum al... 2 | 25
increased circulating total pr... 2 | 20
increased circulating triglyce... 2 | 24
small testis 2 | 37
trunk curl 2 | 15

Disease

ovarian cancer 329 | 8,484
osteosarcoma 279 | 7,933
medulloblastoma, large-cell 218 | 6,234
glioblastoma 213 | 5,572
psoriasis 206 | 6,685
lung cancer 171 | 4,466
atypical teratoid / rhabdoid tumor 144 | 4,369
Cancer 133 | 2,346
invasive ductal carcinoma 129 | 2,950
lung carcinoma 126 | 2,844
malignant mesothelioma 126 | 3,162
intraductal papillary-mucinous neoplasm (IPMN) 124 | 3,289
intraductal papillary-mucinous adenoma (IPMA) 122 | 2,956
pilocytic astrocytoma 119 | 3,086
intraductal papillary-mucinous carcinoma (IPMC) 107 | 2,988
diabetes mellitus 106 | 1,663
pancreatic cancer 103 | 2,300
non-small cell lung cancer 101 | 2,798
ulcerative colitis 101 | 2,087
pediatric high grade glioma 100 | 2,712
subependymal giant cell astrocytoma 99 | 2,287
oligodendroglioma 97 | 2,849
Breast cancer 96 | 3,094
tuberculosis 95 | 1,557
lung adenocarcinoma 93 | 2,713
interstitial cystitis 89 | 2,299
ependymoma 86 | 2,514
primitive neuroectodermal tumor 83 | 3,031
Pick disease 77 | 1,893
pancreatic ductal adenocarcinoma liver metastasis 75 | 1,795
astrocytoma 74 | 1,493
Multiple myeloma 73 | 1,327
Rheumatoid Arthritis 72 | 1,160
Carcinoma 70 | 2,147
adult high grade glioma 69 | 2,148
astrocytic glioma 69 | 2,241
cystic fibrosis 69 | 1,665
group 4 medulloblastoma 68 | 1,875
primary pancreatic ductal adenocarcinoma 67 | 1,271
ductal carcinoma in situ 65 | 1,745
juvenile dermatomyositis 63 | 1,189
pituitary cancer 63 | 1,972
breast carcinoma 62 | 1,614
cutaneous lupus erythematosus 61 | 1,056
Alzheimer's disease 60 | 644
posterior fossa group A ependymoma 60 | 1,511
dermatomyositis 59 | 933
adrenocortical carcinoma 55 | 1,427
colon cancer 55 | 1,475
acute quadriplegic myopathy 54 | 1,157
Neurodegenerative disease 53 | 383
Waldenstrons macroglobulinemia 49 | 765
esophageal adenocarcinoma 49 | 737
medulloblastoma 49 | 1,524
sonic hedgehog group medulloblastoma 48 | 1,482
Kidney disease 46 | 396
posterior fossa group B ependymoma 44 | 1,530
group 3 medulloblastoma 42 | 2,254
Duchenne muscular dystrophy 40 | 602
primary Sjogren syndrome 40 | 789
active Crohn's disease 39 | 918
Atopic dermatitis 38 | 944
spina bifida 38 | 1,064
Obesity 37 | 616
gastric carcinoma 37 | 832
Down syndrome 35 | 548
mucosa-associated lymphoid tissue lymphoma 35 | 480
Hypersensitivity reaction type II disease 33 | 235
non primary Sjogren syndrome sicca 33 | 840
Multiple Sclerosis 32 | 498
atypical teratoid/rhabdoid tumor 32 | 1,095
Atherosclerosis 31 | 275
Hypertension 31 | 287
sarcoidosis 31 | 358
Anemia 30 | 252
Arthritis 30 | 248
pancreatic carcinoma 30 | 567
Liver disease 29 | 219
Parkinson's disease 29 | 364
Asthma 28 | 349
Coronary artery disease 28 | 240
Heart disease 28 | 279
Vascular disease 27 | 281
acute myeloid leukemia 26 | 780
Cerebrovascular disease 25 | 231
nephrosclerosis 25 | 329
Dementia 24 | 129
IGA Glomerulonephritis 24 | 454
progressive supranuclear palsy 24 | 674
Amyotrophic Lateral Sclerosis 23 | 431
Hermansky-Pudlak syndrome 23 | 43
Prostatic Neoplasms 23 | 471
nasopharyngeal carcinoma 23 | 1,056
Schizophrenia 22 | 501
aldosterone-producing adenoma 22 | 664
Crohn's disease 21 | 304
Stomach Neoplasms 21 | 282
head and neck cancer and chronic obstructive pulmonary disease 21 | 237
hepatocellular carcinoma 21 | 532
tuberculosis and treatment for 6 months 21 | 686

Tissue

Female tissues 563 | 18,647
Liver and Pancreas 563 | 18,136
Nervous System 563 | 18,561
Urinary Tract 563 | 18,444
Endocrine System 562 | 18,512
Digestive Tract 561 | 18,473
Cardiovascular System 560 | 17,958
Blood and immune system 559 | 17,995
Male tissues 559 | 17,969
Skin and soft tissues 558 | 18,115
Respiratory system 554 | 17,484

Target Family

Non-IDG 325 | 11,971
Enzyme 183 | 4,146
Transporter 28 | 473
Ion Channel 13 | 341
Kinase 13 | 634
GPCR 5 | 406
Transcription Factor 4 | 1,400

Compartment GO Term

Lytic vacuole 571 | 571
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
Lumican LUM Tbio Non-IDG -2.67820 509.4 209
Apolipoprotein E APOE Tbio Non-IDG -4.17470 15380.4 788
Glypican-3 GPC3 Tbio Non-IDG -2.85848 794.8 523
Vacuolar ATPase assembly integral membrane protein VMA21 VMA21 Tbio Enzyme 1.00 53
Sialidase-3 NEU3 Tbio Enzyme -1.97558 109.4 23
ATP-binding cassette sub-family A member 2 ABCA2 Tbio Transporter -1.41708 32.2 125
Transmembrane 6 superfamily member 1 TM6SF1 Tdark Non-IDG -0.16400 2.15 54
V-type proton ATPase catalytic subunit A ATP6V1A Tbio Enzyme -1.80191 64.7 120
Equilibrative nucleoside transporter 3 SLC29A3 Tbio Transporter -2.36515 247.3 58