Development Level

Tbio 381 | 10,625
Tchem 109 | 1,890
Tdark 53 | 7,003
Tclin 28 | 602

Collection

Ion Channel: IDG Consortium (Targets) 2 | 102
GPCR: IDG Consortium (Targets) 1 | 127

IMPC Phenotype

preweaning lethality, complete... 27 | 633
abnormal behavior 12 | 226
decreased total body fat amoun... 12 | 186
embryonic lethality prior to t... 12 | 187
preweaning lethality, incomple... 10 | 260
decreased body weight 8 | 174
embryonic lethality prior to o... 8 | 148
increased bone mineral content 8 | 92
increased circulating alkaline... 8 | 119
decreased mean corpuscular vol... 7 | 50
increased mean corpuscular hem... 7 | 93
short tibia 7 | 82
decreased body length 6 | 108
decreased circulating glucose ... 6 | 121
decreased circulating serum al... 6 | 79
decreased grip strength 6 | 123
decreased prepulse inhibition 6 | 52
hypoactivity 6 | 89
increased bone mineral density 6 | 52
increased lean body mass 6 | 107
abnormal bone structure 5 | 131
abnormal retina morphology 5 | 100
abnormal retinal pigmentation 5 | 61
abnormal seminal vesicle morph... 5 | 47
abnormal sleep behavior 5 | 63
decreased bone mineral density 5 | 126
decreased circulating HDL chol... 5 | 77
decreased circulating triglyce... 5 | 83
decreased erythrocyte cell num... 5 | 43
decreased mean corpuscular hem... 5 | 34
improved glucose tolerance 5 | 56
increased blood urea nitrogen ... 5 | 44
increased circulating potassiu... 5 | 31
increased circulating sodium l... 5 | 71
increased mean corpuscular vol... 5 | 91
increased or absent threshold ... 5 | 128
small adrenal glands 5 | 15
thrombocytosis 5 | 23
abnormal bone mineralization 4 | 55
abnormal coat-hair pigmentatio... 4 | 54
decreased B cell number 4 | 30
decreased hemoglobin content 4 | 53
decreased lean body mass 4 | 195
decreased leukocyte cell numbe... 4 | 54
decreased rib number 4 | 59
enlarged heart 4 | 111
impaired glucose tolerance 4 | 52
increased circulating choleste... 4 | 53
abnormal embryo size 3 | 112
abnormal epididymis morphology 3 | 31
abnormal iris morphology 3 | 12
abnormal skin morphology 3 | 23
absent pinna reflex 3 | 21
cardiovascular system phenotyp... 3 | 35
decreased CD8-positive, alpha-... 3 | 26
decreased bone mineral content 3 | 157
decreased circulating bilirubi... 3 | 14
decreased circulating choleste... 3 | 85
decreased circulating insulin ... 3 | 75
decreased circulating phosphat... 3 | 15
decreased eosinophil cell numb... 3 | 41
decreased heart weight 3 | 44
decreased lumbar vertebrae num... 3 | 62
decreased monocyte cell number 3 | 28
enlarged lymph nodes 3 | 27
increased B cell number 3 | 23
increased NK cell number 3 | 19
increased circulating HDL chol... 3 | 63
increased circulating LDL chol... 3 | 15
increased effector memory CD8-... 3 | 14
increased fasted circulating g... 3 | 68
increased grip strength 3 | 83
increased leukocyte cell numbe... 3 | 37
increased sacral vertebrae num... 3 | 62
abnormal coat appearance 2 | 25
abnormal coping response 2 | 12
abnormal heart morphology 2 | 51
abnormal kidney morphology 2 | 30
abnormal lung morphology 2 | 15
abnormal rib morphology 2 | 28
abnormal testis morphology 2 | 30
abnormal vibrissa morphology 2 | 17
decreased CD4-positive, alpha ... 2 | 19
decreased T cell number 2 | 31
decreased blood urea nitrogen ... 2 | 31
decreased caudal vertebrae num... 2 | 49
decreased circulating calcium ... 2 | 33
decreased circulating iron lev... 2 | 25
decreased circulating sodium l... 2 | 18
decreased neutrophil cell numb... 2 | 37
enlarged spleen 2 | 26
increased NK T cell number 2 | 11
increased circulating bilirubi... 2 | 16
increased circulating calcium ... 2 | 32
increased circulating chloride... 2 | 43
increased circulating serum al... 2 | 25
increased circulating total pr... 2 | 20
increased circulating triglyce... 2 | 24
small testis 2 | 37
trunk curl 2 | 15

Disease

ovarian cancer 329 | 8,491
osteosarcoma 279 | 7,933
medulloblastoma, large-cell 218 | 6,234
glioblastoma 213 | 5,572
psoriasis 206 | 6,685
lung cancer 172 | 4,473
atypical teratoid / rhabdoid tumor 144 | 4,369
Cancer 133 | 2,346
invasive ductal carcinoma 129 | 2,950
malignant mesothelioma 127 | 3,163
lung carcinoma 126 | 2,844
intraductal papillary-mucinous neoplasm (IPMN) 124 | 3,289
intraductal papillary-mucinous adenoma (IPMA) 122 | 2,956
pilocytic astrocytoma 119 | 3,086
intraductal papillary-mucinous carcinoma (IPMC) 107 | 2,988
diabetes mellitus 106 | 1,663
pancreatic cancer 103 | 2,300
non-small cell lung cancer 101 | 2,798
ulcerative colitis 101 | 2,087
pediatric high grade glioma 100 | 2,712
subependymal giant cell astrocytoma 99 | 2,287
oligodendroglioma 97 | 2,849
Breast cancer 96 | 3,098
tuberculosis 95 | 1,563
lung adenocarcinoma 93 | 2,714
interstitial cystitis 89 | 2,299
ependymoma 86 | 2,514
primitive neuroectodermal tumor 83 | 3,031
Pick disease 77 | 1,893
pancreatic ductal adenocarcinoma liver metastasis 75 | 1,795
astrocytoma 74 | 1,493
Multiple myeloma 73 | 1,327
Rheumatoid Arthritis 72 | 1,170
Carcinoma 70 | 2,147
adult high grade glioma 69 | 2,148
astrocytic glioma 69 | 2,241
cystic fibrosis 69 | 1,670
group 4 medulloblastoma 68 | 1,875
primary pancreatic ductal adenocarcinoma 67 | 1,271
ductal carcinoma in situ 65 | 1,745
juvenile dermatomyositis 63 | 1,189
pituitary cancer 63 | 1,972
breast carcinoma 62 | 1,614
cutaneous lupus erythematosus 61 | 1,056
Alzheimer's disease 60 | 644
posterior fossa group A ependymoma 60 | 1,511
dermatomyositis 59 | 966
adrenocortical carcinoma 55 | 1,427
colon cancer 55 | 1,475
acute quadriplegic myopathy 54 | 1,157
Neurodegenerative disease 53 | 383
Waldenstrons macroglobulinemia 49 | 764
esophageal adenocarcinoma 49 | 737
medulloblastoma 49 | 1,524
sonic hedgehog group medulloblastoma 48 | 1,482
Kidney disease 46 | 397
posterior fossa group B ependymoma 44 | 1,530
group 3 medulloblastoma 42 | 2,254
Duchenne muscular dystrophy 40 | 602
primary Sjogren syndrome 40 | 788
active Crohn's disease 39 | 918
Atopic dermatitis 38 | 944
spina bifida 38 | 1,064
Obesity 37 | 616
gastric carcinoma 37 | 832
Down syndrome 35 | 548
mucosa-associated lymphoid tissue lymphoma 35 | 480
Hypersensitivity reaction type II disease 33 | 235
non primary Sjogren syndrome sicca 33 | 840
Hypertension 32 | 293
Multiple Sclerosis 32 | 498
atypical teratoid/rhabdoid tumor 32 | 1,095
Atherosclerosis 31 | 275
sarcoidosis 31 | 368
Anemia 30 | 252
Arthritis 30 | 248
pancreatic carcinoma 30 | 567
Liver disease 29 | 219
Parkinson's disease 29 | 364
Asthma 28 | 349
Coronary artery disease 28 | 240
Heart disease 28 | 279
Vascular disease 27 | 281
acute myeloid leukemia 26 | 785
Cerebrovascular disease 25 | 231
nephrosclerosis 25 | 329
Dementia 24 | 129
IGA Glomerulonephritis 24 | 454
hepatocellular carcinoma 24 | 550
progressive supranuclear palsy 24 | 674
Amyotrophic Lateral Sclerosis 23 | 432
Hermansky-Pudlak syndrome 23 | 43
Prostatic Neoplasms 23 | 471
nasopharyngeal carcinoma 23 | 1,056
Schizophrenia 22 | 503
aldosterone-producing adenoma 22 | 664
Crohn's disease 21 | 304
Lung disease 21 | 136
Stomach Neoplasms 21 | 282
tuberculosis and treatment for 6 months 21 | 686

Tissue

Female tissues 563 | 18,646
Liver and Pancreas 563 | 18,135
Nervous System 563 | 18,560
Urinary Tract 563 | 18,443
Endocrine System 562 | 18,511
Digestive Tract 561 | 18,472
Cardiovascular System 560 | 17,957
Blood and immune system 559 | 17,994
Male tissues 559 | 17,968
Skin and soft tissues 558 | 18,114
Respiratory system 554 | 17,483

Target Family

Non-IDG 325 | 11,969
Enzyme 183 | 4,146
Transporter 28 | 473
Ion Channel 13 | 341
Kinase 13 | 634
GPCR 5 | 408
Transcription Factor 4 | 1,400

Compartment GO Term

Lysosome 571 | 571
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Huntingtin HTT Tchem Non-IDG -3.32908 2140.8 521
WD repeat-containing protein mio MIOS Tdark Non-IDG -1.44864 27.4 14
Interferon-induced transmembrane protein 3 IFITM3 Tbio Non-IDG -1.87958 126.0 172
N-acetylglucosamine-1-phosphotransferase subunit gamma GNPTG Tbio Enzyme -1.17901 15.7 80
Alternative prion protein PRNP Tbio Non-IDG -3.44085 5471.9 0
Dipeptidyl peptidase 1 CTSC Tchem Enzyme -3.24582 1740.5 143
Alpha-1-antitrypsin SERPINA1 Tbio Non-IDG -3.73976 5495.0 809
Cystatin-S CST4 Tbio Non-IDG -1.82088 50.6 143
Cystatin-C CST3 Tbio Non-IDG -3.48935 3020.7 756
Pro-epidermal growth factor EGF Tbio Non-IDG -3.74596 4837.7 851