Development Level

Tbio 64 | 11,445
Tchem 27 | 1,598
Tdark 4 | 6,588
Tclin 3 | 613

IMPC Phenotype

abnormal heart morphology 3 | 162
enlarged heart 3 | 210
increased bone mineral content 3 | 108
preweaning lethality, complete... 3 | 979
short tibia 3 | 97
small adrenal glands 3 | 16
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
abnormal seminal vesicle morph... 2 | 114
decreased circulating HDL chol... 2 | 68
decreased circulating choleste... 2 | 93
decreased circulating serum al... 2 | 82
decreased total body fat amoun... 2 | 207
enlarged lymph nodes 2 | 37
increased circulating potassiu... 2 | 29
increased lean body mass 2 | 172
preweaning lethality, incomple... 2 | 499
small superior vagus ganglion 2 | 74
thrombocytosis 2 | 27
abnormal bone mineralization 1 | 38
abnormal coat-hair pigmentatio... 1 | 64
abnormal snout morphology 1 | 23
abnormal tail morphology 1 | 25
abnormal testis morphology 1 | 43
cataract 1 | 92
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
embryonic lethality prior to o... 1 | 239
enlarged kidney 1 | 14
hyperactivity 1 | 148
hypoactivity 1 | 132
increased B cell number 1 | 9
increased blood urea nitrogen ... 1 | 48
increased bone mineral density 1 | 72
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating creatini... 1 | 38
increased circulating phosphat... 1 | 26
increased circulating triglyce... 1 | 42
increased grip strength 1 | 41
increased leukocyte cell numbe... 1 | 47
increased neutrophil cell numb... 1 | 46
male infertility 1 | 123
mydriasis 1 | 6
premature death 1 | 5
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small kidney 1 | 16
small seminal vesicle 1 | 10
small testis 1 | 58

Disease

Carcinoma 74 | 11,493
ovarian cancer 61 | 8,520
glioblastoma 47 | 5,792
Autosomal recessive predisposition 43 | 1,442
psoriasis 43 | 6,694
osteosarcoma 41 | 7,950
lung cancer 35 | 4,740
medulloblastoma, large-cell 32 | 6,241
malignant mesothelioma 31 | 3,232
Breast cancer 29 | 3,578
Cancer 29 | 2,499
Astrocytoma, Pilocytic 27 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 27 | 3,291
atypical teratoid / rhabdoid tumor 26 | 5,112
diabetes mellitus 26 | 1,728
Hepatomegaly 24 | 285
invasive ductal carcinoma 24 | 2,951
subependymal giant cell astrocytoma 24 | 2,287
ependymoma 23 | 4,679
Epilepsy 22 | 792
Splenomegaly 22 | 190
intraductal papillary-mucinous adenoma (IPMA) 22 | 2,955
tuberculosis 21 | 2,010
Intellectual disability 20 | 1,016
Seizures 20 | 596
pancreatic cancer 20 | 2,398
Muscle hypotonia 19 | 571
adult high grade glioma 19 | 3,801
astrocytoma 19 | 1,146
lung carcinoma 19 | 2,843
Dull intelligence 18 | 645
Low intelligence 18 | 645
Mental Retardation 18 | 645
Mental deficiency 18 | 645
Multiple myeloma 18 | 1,332
Poor school performance 18 | 645
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,989
Coarse facial features 17 | 108
Congenital deafness 17 | 185
Deafness 17 | 198
Hearing Loss, Partial 17 | 185
Thickened facial skin with coarse facial features 17 | 108
group 3 medulloblastoma 17 | 4,104
hearing impairment 17 | 199
juvenile dermatomyositis 17 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 17 | 1,962
pituitary cancer 17 | 1,972
Duchenne muscular dystrophy 16 | 601
cutaneous lupus erythematosus 16 | 1,057
Neurodegenerative disease 15 | 414
breast carcinoma 15 | 1,638
ductal carcinoma in situ 15 | 1,745
interstitial cystitis 15 | 2,312
non-small cell lung cancer 15 | 2,890
ulcerative colitis 15 | 1,819
Short stature 14 | 531
Kidney cancer 13 | 2,613
Mucopolysaccharidosis 13 | 26
adrenocortical carcinoma 13 | 1,428
cystic fibrosis 13 | 1,696
oligodendroglioma 13 | 2,850
Atopic dermatitis 12 | 952
Cerebellar Ataxia 12 | 304
Rheumatoid arthritis 12 | 1,191
esophageal adenocarcinoma 12 | 737
group 4 medulloblastoma 12 | 1,855
lung adenocarcinoma 12 | 2,716
primary pancreatic ductal adenocarcinoma 12 | 1,109
primitive neuroectodermal tumor 12 | 3,035
Acquired scoliosis 11 | 281
Cognitive delay 11 | 608
Curvature of spine 11 | 282
Global developmental delay 11 | 608
Hernia, Inguinal 11 | 89
Mental and motor retardation 11 | 608
Pfaundler-Hurler Syndrome 11 | 12
acute quadriplegic myopathy 11 | 1,158
colon cancer 11 | 1,478
dermatomyositis 11 | 966
pediatric high grade glioma 11 | 1,064
Hyperkyphosis 10 | 111
Kyphosis deformity of spine 10 | 114
Liver Cirrhosis, Experimental 10 | 769
Osteoporosis 10 | 363
Vascular disease 10 | 319
non primary Sjogren syndrome sicca 10 | 891
sonic hedgehog group medulloblastoma 10 | 467
Anemia 9 | 365
Dementia 9 | 175
Down syndrome 9 | 499
Dysarthria 9 | 192
Hydrocephalus 9 | 152
Hyperreflexia 9 | 209
Macroglossia 9 | 65
Schizophrenia 9 | 1,160
Short neck 9 | 140
Waldenstrons macroglobulinemia 9 | 765
astrocytic glioma 9 | 2,597
gastric carcinoma 9 | 807
primary Sjogren syndrome 9 | 735

Tissue

Endocrine System 93 | 18,159
Blood and immune system 92 | 16,909
Digestive Tract 92 | 17,369
Female tissues 92 | 17,400
Liver and Pancreas 92 | 16,750
Male tissues 92 | 17,142
Nervous System 92 | 16,725
Skin and soft tissues 92 | 17,230
Urinary Tract 92 | 16,678
Cardiovascular System 88 | 15,192
Respiratory system 88 | 16,393

Target Family

Enzyme 49 | 4,145
Non-IDG 47 | 12,091
Kinase 1 | 634
Transporter 1 | 473

Compartment GO Term

Lysosomal lumen 98 | 98
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neuronal vesicle trafficking-associated protein 1 NSG1 Tbio Non-IDG -1.15265 16.1 182
Galactocerebrosidase GALC Tbio Enzyme -2.56924 363.2 143
Glypican-6 GPC6 Tbio Non-IDG -1.33560 21.9 125
Alpha-N-acetylglucosaminidase NAGLU Tbio Enzyme -2.18649 159.9 64
Chitinase domain-containing protein 1 CHID1 Tbio Enzyme -0.81193 6.93 150
Arylsulfatase B ARSB Tbio Enzyme -2.51626 314.5 216
Syndecan-3 SDC3 Tbio Non-IDG -1.86172 78.8 179
Palmitoyl-protein thioesterase 1 PPT1 Tbio Enzyme -2.63966 433.8 305
Versican core protein VCAN Tbio Non-IDG -2.88501 795.4 190
Putative phospholipase B-like 2 PLBD2 Tbio Enzyme -1.70870 47.4 83