Development Level

Tbio 73 | 11,445
Tchem 21 | 1,598
Tdark 9 | 6,588
Tclin 5 | 613

IMPC Phenotype

preweaning lethality, complete... 8 | 979
preweaning lethality, incomple... 6 | 499
abnormal embryo size 3 | 220
decreased body weight 3 | 161
decreased vertical activity 3 | 208
increased total body fat amoun... 3 | 134
abnormal lens morphology 2 | 81
embryonic growth retardation 2 | 106
embryonic lethality prior to t... 2 | 278
increased circulating alkaline... 2 | 122
increased circulating choleste... 2 | 66
increased circulating total pr... 2 | 28
increased heart weight 2 | 62
increased mean corpuscular hem... 2 | 96
increased or absent threshold ... 2 | 101
thrombocytopenia 2 | 56
abnormal embryo turning 1 | 31
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal maxilla morphology 1 | 17
abnormal pericardium morpholog... 1 | 26
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
cataract 1 | 92
decreased CD4-positive, alpha ... 1 | 7
decreased IgG1 level 1 | 8
decreased body length 1 | 101
decreased cardiac muscle contr... 1 | 11
decreased caudal vertebrae num... 1 | 53
decreased circulating alanine ... 1 | 47
decreased circulating calcium ... 1 | 36
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
decreased granulocyte number 1 | 6
decreased heart left ventricle... 1 | 28
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased monocyte cell number 1 | 8
decreased respiratory quotient 1 | 16
decreased threshold for audito... 1 | 26
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
hydrometra 1 | 53
impaired pupillary reflex 1 | 26
increased B cell number 1 | 9
increased circulating LDL chol... 1 | 13
increased circulating amylase ... 1 | 25
increased circulating bilirubi... 1 | 16
increased circulating chloride... 1 | 41
increased circulating free fat... 1 | 20
increased circulating fructosa... 1 | 13
increased circulating serum al... 1 | 22
increased circulating thyroxin... 1 | 7
increased circulating triglyce... 1 | 42
increased erythrocyte cell num... 1 | 39
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 36
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
limb grasping 1 | 41
male infertility 1 | 123
pallor 1 | 34
premature death 1 | 5
prenatal lethality prior to he... 1 | 87
small superior vagus ganglion 1 | 74
thin ventricular wall 1 | 24

Disease

Carcinoma 66 | 11,493
ovarian cancer 61 | 8,520
psoriasis 54 | 6,694
osteosarcoma 43 | 7,950
glioblastoma 42 | 5,792
invasive ductal carcinoma 39 | 2,951
Obesity 37 | 678
lung cancer 37 | 4,740
diabetes mellitus 36 | 1,728
ductal carcinoma in situ 32 | 1,745
medulloblastoma, large-cell 32 | 6,241
Cancer 30 | 2,499
breast carcinoma 28 | 1,638
Fatty liver disease 27 | 103
atypical teratoid / rhabdoid tumor 26 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 26 | 3,291
malignant mesothelioma 26 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 26 | 1,962
Autosomal recessive predisposition 24 | 1,442
lung adenocarcinoma 24 | 2,716
lung carcinoma 24 | 2,843
Astrocytoma, Pilocytic 21 | 3,081
Breast cancer 21 | 3,578
adult high grade glioma 21 | 3,801
ependymoma 21 | 4,679
non-small cell lung cancer 21 | 2,890
Atherosclerosis 20 | 291
fibroadenoma 20 | 559
group 3 medulloblastoma 20 | 4,104
tuberculosis 20 | 2,010
Atopic dermatitis 19 | 952
Lipid metabolism disorder 19 | 114
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
pancreatic cancer 19 | 2,398
Liver Cirrhosis, Experimental 17 | 769
astrocytoma 16 | 1,146
interstitial cystitis 16 | 2,312
pituitary cancer 16 | 1,972
Schizophrenia 15 | 1,160
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
pediatric high grade glioma 15 | 1,064
ulcerative colitis 15 | 1,819
Intellectual disability 14 | 1,016
Polycystic ovary syndrome 14 | 360
acute quadriplegic myopathy 14 | 1,158
adrenocortical carcinoma 14 | 1,428
colon cancer 14 | 1,478
Coronary artery disease 13 | 268
Kidney cancer 13 | 2,613
Lipodystrophy 13 | 40
oligodendroglioma 13 | 2,850
Dull intelligence 12 | 645
Hyperinsulinism 12 | 133
Liver disease 12 | 237
Low intelligence 12 | 645
Mental Retardation 12 | 645
Mental deficiency 12 | 645
Poor school performance 12 | 645
active Crohn's disease 12 | 922
cystic fibrosis 12 | 1,696
esophageal adenocarcinoma 12 | 737
primitive neuroectodermal tumor 12 | 3,035
Carcinoma, Hepatocellular 11 | 228
Duchenne muscular dystrophy 11 | 601
Hypertension 11 | 396
Hypertensive disease 11 | 292
Liver carcinoma 11 | 240
Pick disease 11 | 1,894
Hyperglycemia 10 | 137
Insulin Resistance 10 | 72
Seizures 10 | 596
Steatohepatitis 10 | 44
active ulcerative colitis 10 | 764
autosomal dominant Emery-Dreifuss muscular dystrophy 10 | 510
dermatomyositis 10 | 966
non primary Sjogren syndrome sicca 10 | 891
subependymal giant cell astrocytoma 10 | 2,287
Cerebrovascular disease 9 | 238
Fatty Liver 9 | 70
Heart disease 9 | 306
Heart failure 9 | 162
Hepatomegaly 9 | 285
Hypertriglyceridemia result 9 | 37
Kidney disease 9 | 430
Neurodegenerative disease 9 | 414
Osteoporosis 9 | 363
Rheumatoid arthritis 9 | 1,191
astrocytic glioma 9 | 2,597
juvenile dermatomyositis 9 | 1,187
Acanthosis Nigricans 8 | 27
Epilepsy 8 | 792
Multiple myeloma 8 | 1,332
Muscle hypotonia 8 | 571
Cognitive delay 7 | 608
Global developmental delay 7 | 608
Mental and motor retardation 7 | 608
Prostatic Neoplasms 7 | 495
Small head 7 | 374
aldosterone-producing adenoma 7 | 665
primary pancreatic ductal adenocarcinoma 7 | 1,109

Tissue

Female tissues 104 | 17,400
Digestive Tract 103 | 17,369
Endocrine System 103 | 18,159
Liver and Pancreas 103 | 16,750
Skin and soft tissues 103 | 17,230
Blood and immune system 101 | 16,909
Male tissues 100 | 17,142
Nervous System 100 | 16,725
Respiratory system 100 | 16,393
Urinary Tract 99 | 16,678
Cardiovascular System 98 | 15,192

Target Family

Enzyme 52 | 4,145
Non-IDG 49 | 12,091
Transcription Factor 4 | 1,400
Kinase 1 | 634
Nuclear Receptor 1 | 48
Transporter 1 | 473

Compartment GO Term

Lipid particle 108 | 108
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Insulin INS Tbio Non-IDG -5.17849 146933.7 2197
Pro-opiomelanocortin POMC Tbio Non-IDG -4.56004 36591.2 1334
Leptin LEP Tbio Non-IDG -4.17777 16050.7 1012
Apolipoprotein E APOE Tbio Non-IDG -4.20176 15904.9 976