Development Level

Tbio 18 | 11,445
Tchem 5 | 1,598

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal embryo size 2 | 220
decreased mean platelet volume 2 | 25
embryonic lethality prior to t... 2 | 278
increased mean platelet volume 2 | 45
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal neural tube closure 1 | 46
absent startle reflex 1 | 24
decreased basophil cell number 1 | 16
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased circulating alanine ... 1 | 47
decreased circulating fructosa... 1 | 30
decreased circulating iron lev... 1 | 32
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased neutrophil cell numb... 1 | 42
embryonic lethality prior to o... 1 | 239
increased circulating bilirubi... 1 | 16
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased prepulse inhibition 1 | 32
increased red blood cell distr... 1 | 34
male infertility 1 | 123
polycystic kidney 1 | 15
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
thrombocytosis 1 | 27

Disease

Carcinoma 17 | 11,493
Neurodegenerative disease 15 | 414
Parkinson's disease 15 | 392
Dementia 13 | 175
ovarian cancer 13 | 8,520
osteosarcoma 11 | 7,950
Alzheimer's disease 10 | 658
Multiple system atrophy 10 | 29
Parkinsonian Disorders 10 | 56
group 3 medulloblastoma 10 | 4,104
Parkinson Disease 9 | 64
glioblastoma 9 | 5,792
psoriasis 9 | 6,694
Astrocytoma, Pilocytic 8 | 3,081
Depressive disorder 8 | 409
Muscle Rigidity 8 | 49
atypical teratoid / rhabdoid tumor 8 | 5,112
medulloblastoma, large-cell 8 | 6,241
Amyotrophic lateral sclerosis 7 | 451
Bradykinesia 7 | 34
Cancer 7 | 2,499
Nerve Degeneration 7 | 121
Pick disease 7 | 1,894
Toxic encephalopathy 7 | 141
adult high grade glioma 7 | 3,801
ependymoma 7 | 4,679
oligodendroglioma 7 | 2,850
Dysarthria 6 | 192
Hyperreflexia 6 | 209
Multiple myeloma 6 | 1,332
PARKINSON DISEASE, LATE-ONSET 6 | 20
Schizophrenia 6 | 1,160
diabetes mellitus 6 | 1,728
Autosomal recessive predisposition 5 | 1,442
Deglutition Disorders 5 | 132
Dystonia 5 | 164
Dystonic disease 5 | 106
Frontotemporal dementia 5 | 51
Muscle Spasticity 5 | 195
PARKINSON DISEASE 19, JUVENILE-ONSET 5 | 10
Postural instability 5 | 19
Young onset Parkinson disease 5 | 10
astrocytic glioma 5 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
progressive supranuclear palsy 5 | 676
Adult onset 4 | 82
Anxiety 4 | 136
Anxiety disease 4 | 113
Aphasia 4 | 26
Apraxia 4 | 26
Brain disease 4 | 96
Breast cancer 4 | 3,578
Huntington's disease 4 | 76
Kidney cancer 4 | 2,613
Lewy Body Disease 4 | 21
Manganese Poisoning 4 | 11
Movement disease 4 | 11
Neurodegenerative Disorders 4 | 79
Neuronal loss 4 | 25
Pick's disease 4 | 15
colon cancer 4 | 1,478
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
lung cancer 4 | 4,740
lung carcinoma 4 | 2,843
primitive neuroectodermal tumor 4 | 3,035
subependymal giant cell astrocytoma 4 | 2,287
Akinesia 3 | 13
Apathy 3 | 16
Autosomal dominant late onset Parkinson disease 3 | 7
Babinski Reflex 3 | 100
Bipolar Disorder 3 | 666
Dementia, Lewy Body 3 | 3
Dyspnea 3 | 76
Fatigue 3 | 182
Gait abnormality 3 | 135
Hypokinesia 3 | 19
Lateral sclerosis 3 | 15
Lewy body dementia 3 | 4
Myoclonus 3 | 74
Personality change 3 | 23
Rapidly progressive 3 | 27
Rapidly progressive disorder 3 | 27
Resting Tremor 3 | 9
Tremor 3 | 113
Weight decreased 3 | 103
malignant mesothelioma 3 | 3,232
non primary Sjogren syndrome sicca 3 | 891
pituitary cancer 3 | 1,972
tuberculosis 3 | 2,010
Disease Models, Animal 2 | 155
Generalized muscle weakness 2 | 57
Isolated cases 2 | 72
Neurogenic Muscular Atrophy 2 | 139
Neurogenic muscle atrophy, especially in the lower limbs 2 | 139
Osteoporosis 2 | 363
Respiratory Failure 2 | 104
Skeletal muscle atrophy 2 | 139
Slow progression 2 | 89
Urgency of micturition 2 | 14
muscle degeneration 2 | 139

Tissue

Blood and immune system 23 | 16,909
Cardiovascular System 23 | 15,192
Digestive Tract 23 | 17,369
Endocrine System 23 | 18,159
Female tissues 23 | 17,400
Liver and Pancreas 23 | 16,750
Nervous System 23 | 16,725
Skin and soft tissues 23 | 17,230
Urinary Tract 23 | 16,678
Male tissues 22 | 17,142
Respiratory system 22 | 16,393

Target Family

Non-IDG 15 | 12,091
Enzyme 4 | 4,145
Kinase 2 | 634
Transcription Factor 1 | 1,400
Transporter 1 | 473

Compartment GO Term

Lewy body 23 | 23
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Huntingtin HTT Tchem Non-IDG -3.36282 2294.8 599
Gamma-synuclein SNCG Tbio Non-IDG -2.24895 187.3 294
Cytospin-B SPECC1 Tbio Non-IDG -1.96094 87.4 157
RNA-binding protein 45 RBM45 Tbio Non-IDG -1.34133 23.0 84
Transmembrane protein 230 TMEM230 Tbio Non-IDG -1.27510 18.6 110
Beta-synuclein SNCB Tbio Non-IDG -2.05833 98.5 287
Glucosylceramidase GBA Tchem Enzyme -3.22080 1617.1 299
Protein/nucleic acid deglycase DJ-1 PARK7 Tbio Enzyme -2.89261 835.5 625
F-box only protein 7 FBXO7 Tbio Non-IDG -2.07231 118.6 100
Serine/threonine-protein kinase PINK1, mitochondrial PINK1 Tbio Kinase -2.81574 706.5 546