Development Level

Tbio 91 | 11,445
Tchem 13 | 1,598
Tclin 12 | 613
Tdark 7 | 6,588

Collection

GPCR: IDG Consortium (Targets) 1 | 126
Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

decreased body weight 6 | 161
preweaning lethality, complete... 5 | 979
decreased circulating triglyce... 4 | 79
abnormal behavior 3 | 298
abnormal embryo size 3 | 220
decreased circulating LDL chol... 3 | 38
decreased circulating choleste... 3 | 93
embryonic growth retardation 3 | 106
increased lean body mass 3 | 172
abnormal sleep behavior 2 | 70
cardiovascular system phenotyp... 2 | 36
decreased T cell number 2 | 15
decreased circulating HDL chol... 2 | 68
decreased circulating alanine ... 2 | 47
decreased circulating glucose ... 2 | 126
decreased circulating insulin ... 2 | 76
decreased circulating serum al... 2 | 82
decreased grip strength 2 | 116
decreased leukocyte cell numbe... 2 | 73
decreased total body fat amoun... 2 | 207
embryonic lethality prior to t... 2 | 278
hyperactivity 2 | 148
impaired glucose tolerance 2 | 75
improved glucose tolerance 2 | 79
increased circulating alkaline... 2 | 122
increased circulating triglyce... 2 | 42
increased fasted circulating g... 2 | 76
increased vertical activity 2 | 24
preweaning lethality, incomple... 2 | 499
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal coping response 1 | 1
abnormal digestive system phys... 1 | 1
abnormal eye morphology 1 | 68
abnormal glucose homeostasis 1 | 4
abnormal lens morphology 1 | 81
abnormal limb bud morphology 1 | 17
abnormal liver morphology 1 | 17
abnormal locomotor behavior 1 | 24
abnormal placenta size 1 | 20
abnormal response to tactile s... 1 | 17
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
abnormal urinary bladder morph... 1 | 11
abnormal vibrissa morphology 1 | 25
abnormal whole-body plethysmog... 1 | 4
absent vibrissae 1 | 12
convulsive seizures 1 | 13
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased IgE level 1 | 6
decreased IgG1 level 1 | 8
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating chloride... 1 | 30
decreased circulating fructosa... 1 | 30
decreased circulating total pr... 1 | 49
decreased coping response 1 | 8
decreased heart rate variabili... 1 | 13
decreased hemoglobin content 1 | 68
decreased lactate dehydrogenas... 1 | 16
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
decreased vertical activity 1 | 208
edema 1 | 59
enlarged spleen 1 | 41
increased IgG2b level 1 | 1
increased blood urea nitrogen ... 1 | 48
increased bone mineral density 1 | 72
increased circulating LDL chol... 1 | 13
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating glucose ... 1 | 24
increased circulating phosphat... 1 | 26
increased circulating total pr... 1 | 28
increased heart rate variabili... 1 | 7
increased heart weight 1 | 62
increased mature B cell number 1 | 1
increased mean corpuscular vol... 1 | 92
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
pale yolk sac 1 | 25
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
small thymus 1 | 16
thrombocytosis 1 | 27
tremors 1 | 39

Disease

Carcinoma 100 | 11,493
osteosarcoma 73 | 7,950
ovarian cancer 71 | 8,520
glioblastoma 70 | 5,792
medulloblastoma, large-cell 68 | 6,241
ependymoma 55 | 4,679
psoriasis 54 | 6,694
atypical teratoid / rhabdoid tumor 53 | 5,112
Astrocytoma, Pilocytic 47 | 3,081
Breast cancer 45 | 3,578
lung cancer 44 | 4,740
oligodendroglioma 43 | 2,850
adult high grade glioma 42 | 3,801
group 3 medulloblastoma 42 | 4,104
lung adenocarcinoma 41 | 2,716
malignant mesothelioma 40 | 3,232
non-small cell lung cancer 38 | 2,890
lung carcinoma 37 | 2,843
invasive ductal carcinoma 36 | 2,951
Cancer 35 | 2,499
interstitial cystitis 34 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 34 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 34 | 3,291
astrocytic glioma 33 | 2,597
subependymal giant cell astrocytoma 33 | 2,287
Kidney cancer 32 | 2,613
pancreatic cancer 32 | 2,398
intraductal papillary-mucinous carcinoma (IPMC) 30 | 2,989
primitive neuroectodermal tumor 28 | 3,035
breast carcinoma 27 | 1,638
Pick disease 25 | 1,894
pituitary cancer 23 | 1,972
ulcerative colitis 23 | 1,819
adrenocortical carcinoma 22 | 1,428
colon cancer 21 | 1,478
cystic fibrosis 20 | 1,696
diabetes mellitus 19 | 1,728
ductal carcinoma in situ 19 | 1,745
tuberculosis 18 | 2,010
acute quadriplegic myopathy 17 | 1,158
cutaneous lupus erythematosus 16 | 1,057
group 4 medulloblastoma 16 | 1,855
spina bifida 16 | 1,074
juvenile dermatomyositis 15 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,962
pediatric high grade glioma 15 | 1,064
Schizophrenia 14 | 1,160
primary pancreatic ductal adenocarcinoma 14 | 1,109
Down syndrome 13 | 499
Liver Cirrhosis, Experimental 13 | 769
Multiple Sclerosis 13 | 540
astrocytoma 13 | 1,146
dermatomyositis 13 | 966
Autosomal recessive predisposition 12 | 1,442
Duchenne muscular dystrophy 12 | 601
Intellectual disability 12 | 1,016
Liver cancer 12 | 604
Melanoma 12 | 711
fibroadenoma 12 | 559
gastric carcinoma 12 | 807
Alzheimer's disease 11 | 658
autosomal dominant Emery-Dreifuss muscular dystrophy 11 | 510
Atopic dermatitis 10 | 952
Bipolar Disorder 10 | 666
Epilepsy 10 | 792
Neuropathy 10 | 261
Waldenstrons macroglobulinemia 10 | 765
aldosterone-producing adenoma 10 | 665
nasopharyngeal carcinoma 10 | 1,058
primary Sjogren syndrome 10 | 735
Muscle hypotonia 9 | 571
progressive supranuclear palsy 9 | 676
sonic hedgehog group medulloblastoma 9 | 467
Amyotrophic lateral sclerosis 8 | 451
Autistic Disorder 8 | 364
Breast Neoplasms 8 | 445
Cerebellar Ataxia 8 | 304
Mammary Neoplasms 8 | 425
Mental Depression 8 | 333
Multiple myeloma 8 | 1,332
Skin cancer 8 | 469
esophageal adenocarcinoma 8 | 737
pancreatic carcinoma 8 | 562
Chronic Lymphocytic Leukemia 7 | 262
Depressive disorder 7 | 409
Neoplasm Metastasis 7 | 168
Neurodegenerative disease 7 | 414
Rheumatoid arthritis 7 | 1,191
medulloblastoma 7 | 720
mucosa-associated lymphoid tissue lymphoma 7 | 484
Asthma 6 | 385
Dull intelligence 6 | 645
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Obesity 6 | 678
Poor school performance 6 | 645
Prostatic Neoplasms 6 | 495
Seizures 6 | 596
nephrosclerosis 6 | 333

Tissue

Endocrine System 121 | 18,159
Digestive Tract 120 | 17,369
Male tissues 120 | 17,142
Skin and soft tissues 120 | 17,230
Blood and immune system 119 | 16,909
Female tissues 119 | 17,400
Liver and Pancreas 119 | 16,750
Nervous System 119 | 16,725
Urinary Tract 119 | 16,678
Respiratory system 115 | 16,393
Cardiovascular System 113 | 15,192

Target Family

Non-IDG 80 | 12,091
Enzyme 20 | 4,145
Kinase 10 | 634
Ion Channel 9 | 344
GPCR 2 | 408
Transporter 2 | 473

Compartment GO Term

Leading edge membrane 123 | 123
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adenomatous polyposis coli protein 2 APC2 Tbio Non-IDG -1.50271 33.3 93
Nesprin-2 SYNE2 Tbio Non-IDG -2.62747 380.6 39
Lysosome-associated membrane glycoprotein 5 LAMP5 Tbio Non-IDG -0.81661 7.67 83
Calcium and integrin-binding protein 1 CIB1 Tbio Non-IDG -2.08897 121.1 264
Potassium voltage-gated channel subfamily A member 2 KCNA2 Tclin Ion Channel -2.55550 343.3 205
Roundabout homolog 2 ROBO2 Tbio Non-IDG -1.89275 74.1 161
Zinc transporter ZIP6 SLC39A6 Tbio Transporter -1.66663 50.0 172
Adhesion G protein-coupled receptor E2 ADGRE2 Tbio GPCR -1.67862 48.2 312
Transient receptor potential cation channel subfamily V member 4 TRPV4 Tchem Ion Channel -2.86016 747.3 258
Contactin-associated protein-like 2 CNTNAP2 Tbio Non-IDG -2.36156 228.4 191