Development Level

Tbio 107 | 11,445
Tdark 15 | 6,588
Tchem 9 | 1,598
Tclin 2 | 613

IMPC Phenotype

preweaning lethality, complete... 13 | 979
abnormal behavior 5 | 298
preweaning lethality, incomple... 5 | 499
embryonic lethality prior to o... 4 | 239
hypoactivity 4 | 132
prolonged QT interval 4 | 38
abnormal embryo size 3 | 220
abnormal lens morphology 3 | 81
cataract 3 | 92
increased fasted circulating g... 3 | 76
increased lean body mass 3 | 172
increased startle reflex 3 | 112
prolonged ST segment 3 | 36
abnormal body wall morphology 2 | 9
abnormal craniofacial morpholo... 2 | 33
abnormal epididymis morphology 2 | 42
abnormal kidney morphology 2 | 65
abnormal sleep behavior 2 | 70
decreased blood urea nitrogen ... 2 | 51
decreased body weight 2 | 161
decreased circulating insulin ... 2 | 76
decreased total body fat amoun... 2 | 207
edema 2 | 59
enlarged epididymis 2 | 31
enlarged kidney 2 | 14
increased circulating potassiu... 2 | 29
increased leukocyte cell numbe... 2 | 47
increased mean corpuscular hem... 2 | 96
thrombocytosis 2 | 27
abnormal QT variability 1 | 10
abnormal behavioral response t... 1 | 66
abnormal eye morphology 1 | 68
abnormal eye size 1 | 7
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal hindbrain morphology 1 | 10
abnormal hindlimb morphology 1 | 2
abnormal iris morphology 1 | 13
abnormal limb position 1 | 3
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal pelvic girdle bone mo... 1 | 12
abnormal pericardium morpholog... 1 | 26
abnormal response to new envir... 1 | 10
abnormal retinal inner nuclear... 1 | 8
abnormal skin coloration 1 | 25
abnormal skin morphology 1 | 50
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 43
abnormal thoracic cage shape 1 | 3
abnormal vibrissa morphology 1 | 25
decreased circulating LDL chol... 1 | 38
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased total retina thickne... 1 | 17
embryonic lethality prior to t... 1 | 278
enlarged adrenal glands 1 | 3
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
enlarged uterus 1 | 11
hydrometra 1 | 53
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased heart rate 1 | 23
increased mean corpuscular vol... 1 | 92
irregularly shaped pupil 1 | 7
limb grasping 1 | 41
polycystic kidney 1 | 15
prenatal lethality prior to he... 1 | 87
prolonged PR interval 1 | 15
prolonged QRS complex duration 1 | 8
protruding tongue 1 | 3
short tibia 1 | 97

Disease

ovarian cancer 83 | 8,520
Carcinoma 64 | 11,493
osteosarcoma 53 | 7,950
medulloblastoma, large-cell 46 | 6,241
glioblastoma 45 | 5,792
psoriasis 36 | 6,694
atypical teratoid / rhabdoid tumor 34 | 5,112
ependymoma 31 | 4,679
lung cancer 30 | 4,740
adult high grade glioma 27 | 3,801
tuberculosis 27 | 2,010
pancreatic ductal adenocarcinoma liver metastasis 25 | 1,962
Astrocytoma, Pilocytic 24 | 3,081
pancreatic cancer 23 | 2,398
Breast cancer 22 | 3,578
Multiple myeloma 22 | 1,332
intraductal papillary-mucinous neoplasm (IPMN) 22 | 3,291
oligodendroglioma 22 | 2,850
lung carcinoma 21 | 2,843
malignant mesothelioma 21 | 3,232
group 3 medulloblastoma 20 | 4,104
invasive ductal carcinoma 20 | 2,951
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,989
Pick disease 16 | 1,894
interstitial cystitis 16 | 2,312
primitive neuroectodermal tumor 16 | 3,035
Kidney cancer 15 | 2,613
astrocytic glioma 15 | 2,597
breast carcinoma 15 | 1,638
diabetes mellitus 15 | 1,728
subependymal giant cell astrocytoma 15 | 2,287
Rheumatoid arthritis 14 | 1,191
adrenocortical carcinoma 14 | 1,428
group 4 medulloblastoma 14 | 1,855
non-small cell lung cancer 14 | 2,890
Cancer 13 | 2,499
juvenile dermatomyositis 13 | 1,187
Waldenstrons macroglobulinemia 12 | 765
dermatomyositis 12 | 966
lung adenocarcinoma 12 | 2,716
primary pancreatic ductal adenocarcinoma 12 | 1,109
Autosomal recessive predisposition 11 | 1,442
acute quadriplegic myopathy 11 | 1,158
ductal carcinoma in situ 11 | 1,745
pediatric high grade glioma 11 | 1,064
pituitary cancer 11 | 1,972
ulcerative colitis 11 | 1,819
Down syndrome 10 | 499
Neurodegenerative disease 10 | 414
colon cancer 10 | 1,478
Intellectual disability 9 | 1,016
Multiple Sclerosis 9 | 540
active Crohn's disease 9 | 922
active ulcerative colitis 9 | 764
astrocytoma 9 | 1,146
cystic fibrosis 9 | 1,696
esophageal adenocarcinoma 8 | 737
progressive supranuclear palsy 8 | 676
Alzheimer's disease 7 | 658
Duchenne muscular dystrophy 7 | 601
Epilepsy 7 | 792
aldosterone-producing adenoma 7 | 665
pancreatic carcinoma 7 | 562
primary Sjogren syndrome 7 | 735
spina bifida 7 | 1,074
ARC syndrome 6 | 13
Schizophrenia 6 | 1,160
cutaneous lupus erythematosus 6 | 1,057
mucosa-associated lymphoid tissue lymphoma 6 | 484
non primary Sjogren syndrome sicca 6 | 891
Liver Cirrhosis, Experimental 5 | 769
Liver disease 5 | 237
Muscle Spasticity 5 | 195
Neuropathy 5 | 261
Systemic lupus erythematosus 5 | 194
acute myeloid leukemia 5 | 783
fibroadenoma 5 | 559
gastric carcinoma 5 | 807
hereditary spastic paraplegia 5 | 318
sarcoidosis 5 | 370
Absent reflex 4 | 92
Absent tendon reflex 4 | 92
Amyotrophic lateral sclerosis 4 | 451
Autistic Disorder 4 | 364
Decreased tendon reflex 4 | 122
Dementia 4 | 175
Dysarthria 4 | 192
Hepatitis B 4 | 108
Hepatomegaly 4 | 285
Hermansky-Pudlak syndrome 4 | 42
Hypersensitivity reaction type II disease 4 | 253
Narcolepsy 4 | 72
Parkinson's disease 4 | 392
Reflex, Deep Tendon, Absent 4 | 92
Vasculitis 4 | 80
head and neck cancer and chronic obstructive pulmonary disease 4 | 239
hepatocellular carcinoma 4 | 547
sonic hedgehog group medulloblastoma 4 | 467
tuberculosis and treatment for 6 months 4 | 409

Tissue

Endocrine System 127 | 18,159
Blood and immune system 125 | 16,909
Digestive Tract 125 | 17,369
Female tissues 125 | 17,400
Male tissues 125 | 17,142
Nervous System 125 | 16,725
Respiratory system 125 | 16,393
Skin and soft tissues 125 | 17,230
Cardiovascular System 124 | 15,192
Liver and Pancreas 124 | 16,750
Urinary Tract 124 | 16,678

Target Family

Non-IDG 96 | 12,091
Enzyme 18 | 4,145
Transporter 9 | 473
Ion Channel 5 | 344
Kinase 3 | 634
Transcription Factor 2 | 1,400

Compartment GO Term

Late endosome membrane 133 | 133
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sorting nexin-14 SNX14 Tbio Non-IDG -0.86091 6.82 56
WD repeat-containing protein 91 WDR91 Tbio Non-IDG -0.72903 5.46 54
TIR domain-containing adapter molecule 2 TICAM2 Tbio Non-IDG -1.18212 14.6 258
Neuronal vesicle trafficking-associated protein 1 NSG1 Tbio Non-IDG -1.15265 16.1 182
High affinity nerve growth factor receptor NTRK1 Tclin Kinase -3.05841 1050.9 1092
ATP-binding cassette sub-family A member 5 ABCA5 Tbio Transporter -1.09683 13.2 131
ADP-ribosylation factor-like protein 8B ARL8B Tbio Enzyme -0.99083 12.0 99
NEDD4 family-interacting protein 2 NDFIP2 Tbio Non-IDG -0.67951 5.49 37
MIT domain-containing protein 1 MITD1 Tbio Non-IDG -0.25556 2.10 59
Lysosomal-associated transmembrane protein 4B LAPTM4B Tbio Non-IDG -1.90763 86.1 91