Development Level

Tbio 163 | 10,625
Tchem 26 | 1,890
Tdark 25 | 7,003
Tclin 11 | 602

IMPC Term

preweaning lethality, complete... 12 | 633
abnormal behavior 7 | 226
preweaning lethality, incomple... 6 | 260
hypoactivity 5 | 89
decreased body weight 4 | 174
embryonic lethality prior to o... 4 | 148
decreased grip strength 3 | 123
decreased total body fat amoun... 3 | 186
thrombocytosis 3 | 23
abnormal body wall morphology 2 | 7
abnormal embryo size 2 | 112
abnormal epididymis morphology 2 | 31
abnormal gait 2 | 51
abnormal kidney morphology 2 | 30
abnormal retina morphology 2 | 100
abnormal sleep behavior 2 | 63
decreased blood urea nitrogen ... 2 | 31
decreased body length 2 | 108
decreased bone mineral density 2 | 126
decreased circulating insulin ... 2 | 75
decreased lean body mass 2 | 195
decreased leukocyte cell numbe... 2 | 54
decreased mean corpuscular hem... 2 | 34
decreased total retina thickne... 2 | 20
embryonic lethality prior to t... 2 | 187
enlarged epididymis 2 | 27
impaired glucose tolerance 2 | 52
improved glucose tolerance 2 | 56
increased bone mineral content 2 | 92
increased circulating potassiu... 2 | 31
increased circulating sodium l... 2 | 71
increased exploration in new e... 2 | 56
increased fasted circulating g... 2 | 68
increased leukocyte cell numbe... 2 | 37
increased mean corpuscular vol... 2 | 91
increased or absent threshold ... 2 | 128
straub tail 2 | 26
abnormal QRS complex 1 | 25
abnormal coping response 1 | 12
abnormal eye size 1 | 11
abnormal femur morphology 1 | 14
abnormal hindbrain development 1 | 24
abnormal iris morphology 1 | 12
abnormal limb position 1 | 3
abnormal midbrain development 1 | 22
abnormal motor capabilities/co... 1 | 4
abnormal neural tube closure 1 | 37
abnormal pelvic girdle bone mo... 1 | 11
abnormal retinal inner nuclear... 1 | 5
abnormal rib morphology 1 | 28
abnormal skin coloration 1 | 18
abnormal skin morphology 1 | 23
abnormal testis morphology 1 | 30
abnormal vibrissa morphology 1 | 17
absent startle reflex 1 | 15
absent vibrissae 1 | 14
decreased CD5-positive Ly6C-po... 1 | 4
decreased Ly6C low monocyte nu... 1 | 23
decreased basophil cell number 1 | 11
decreased bone mineral content 1 | 157
decreased cervical vertebrae n... 1 | 12
decreased circulating alkaline... 1 | 41
decreased circulating aspartat... 1 | 27
decreased circulating bilirubi... 1 | 14
decreased circulating free fat... 1 | 39
decreased circulating triglyce... 1 | 83
decreased eosinophil cell numb... 1 | 41
decreased fasted circulating g... 1 | 49
decreased heart rate 1 | 10
decreased heart weight 1 | 44
decreased lumbar vertebrae num... 1 | 62
decreased monocyte cell number 1 | 28
decreased prepulse inhibition 1 | 52
decreased red blood cell distr... 1 | 11
decreased rib number 1 | 59
decreased startle reflex 1 | 48
enlarged lymph nodes 1 | 27
enlarged spleen 1 | 26
hyperactivity 1 | 108
increased B cell number 1 | 23
increased NK cell number 1 | 19
increased blood urea nitrogen ... 1 | 44
increased body length 1 | 20
increased body weight 1 | 42
increased circulating alkaline... 1 | 119
increased circulating calcium ... 1 | 32
increased circulating serum al... 1 | 25
increased erythrocyte cell num... 1 | 26
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased mature B cell number 1 | 12
increased mean corpuscular hem... 1 | 93
increased sacral vertebrae num... 1 | 62
increased vertical activity 1 | 18
limb grasping 1 | 35
premature death 1 | 5
prenatal lethality prior to he... 1 | 64
short tibia 1 | 82
shortened RR interval 1 | 19
small adrenal glands 1 | 15

Disease

ovarian cancer 138 | 8,484
osteosarcoma 104 | 7,933
medulloblastoma, large-cell 82 | 6,234
glioblastoma 76 | 5,572
psoriasis 76 | 6,685
lung cancer 62 | 4,466
atypical teratoid / rhabdoid tumor 53 | 4,369
Multiple myeloma 41 | 1,327
intraductal papillary-mucinous neoplasm (IPMN) 41 | 3,289
pilocytic astrocytoma 40 | 3,086
Cancer 39 | 2,346
tuberculosis 39 | 1,557
malignant mesothelioma 38 | 3,162
pancreatic cancer 38 | 2,300
Breast cancer 37 | 3,094
intraductal papillary-mucinous carcinoma (IPMC) 37 | 2,988
lung carcinoma 37 | 2,844
invasive ductal carcinoma 36 | 2,950
oligodendroglioma 36 | 2,849
pancreatic ductal adenocarcinoma liver metastasis 36 | 1,795
pediatric high grade glioma 36 | 2,712
intraductal papillary-mucinous adenoma (IPMA) 35 | 2,956
ependymoma 33 | 2,514
diabetes mellitus 32 | 1,663
Pick disease 31 | 1,893
subependymal giant cell astrocytoma 31 | 2,287
non-small cell lung cancer 30 | 2,798
lung adenocarcinoma 29 | 2,713
Carcinoma 27 | 2,147
group 4 medulloblastoma 27 | 1,875
astrocytoma 26 | 1,493
dermatomyositis 26 | 933
ulcerative colitis 26 | 2,087
Rheumatoid Arthritis 25 | 1,160
juvenile dermatomyositis 25 | 1,189
Neurodegenerative disease 24 | 383
acute quadriplegic myopathy 24 | 1,157
interstitial cystitis 24 | 2,299
primary pancreatic ductal adenocarcinoma 24 | 1,271
primitive neuroectodermal tumor 24 | 3,031
medulloblastoma 22 | 1,524
Alzheimer's disease 21 | 644
astrocytic glioma 21 | 2,241
ductal carcinoma in situ 21 | 1,745
pituitary cancer 21 | 1,972
breast carcinoma 20 | 1,614
adrenocortical carcinoma 19 | 1,427
adult high grade glioma 19 | 2,148
posterior fossa group A ependymoma 19 | 1,511
Waldenstrons macroglobulinemia 18 | 765
Multiple Sclerosis 17 | 498
colon cancer 17 | 1,475
cystic fibrosis 17 | 1,665
esophageal adenocarcinoma 17 | 737
spina bifida 17 | 1,064
Down syndrome 16 | 548
tuberculosis and treatment for 6 months 15 | 686
non primary Sjogren syndrome sicca 13 | 840
primary Sjogren syndrome 13 | 789
pancreatic carcinoma 12 | 567
progressive supranuclear palsy 12 | 674
Duchenne muscular dystrophy 11 | 602
active Crohn's disease 11 | 918
atypical teratoid/rhabdoid tumor 11 | 1,095
mucosa-associated lymphoid tissue lymphoma 11 | 480
sonic hedgehog group medulloblastoma 11 | 1,482
Parkinson's disease 10 | 364
active ulcerative colitis 10 | 477
acute myeloid leukemia 10 | 780
gastric carcinoma 10 | 832
Dementia 9 | 129
Hermansky-Pudlak syndrome 9 | 43
Prostatic Neoplasms 9 | 471
Vascular disease 9 | 281
aldosterone-producing adenoma 9 | 664
cutaneous lupus erythematosus 9 | 1,056
hereditary spastic paraplegia 9 | 313
ARC syndrome 8 | 14
Amyotrophic Lateral Sclerosis 8 | 431
IGA Glomerulonephritis 8 | 454
Liver disease 8 | 219
Neoplasm Invasiveness 8 | 127
group 3 medulloblastoma 8 | 2,254
sarcoidosis 8 | 358
Epilepsy 7 | 346
Intellectual disability 7 | 573
Juvenile arthritis 7 | 124
Mammary Neoplasms 7 | 410
Obesity 7 | 616
Stomach Neoplasms 7 | 282
gastric cancer 7 | 430
hepatocellular carcinoma 7 | 532
interstitial lung disease 7 | 291
Asthma 6 | 349
Endometriosis 6 | 535
Hypersensitivity reaction type II disease 6 | 235
Peripheral Neuropathy 6 | 303
Schizophrenia 6 | 501
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 499
fibroadenoma 6 | 557

Tissue

Nervous System 218 | 18,561
Digestive Tract 217 | 18,473
Endocrine System 217 | 18,512
Female tissues 217 | 18,647
Male tissues 217 | 17,969
Urinary Tract 217 | 18,444
Cardiovascular System 216 | 17,958
Liver and Pancreas 216 | 18,136
Respiratory system 215 | 17,484
Skin and soft tissues 215 | 18,115
Blood and immune system 214 | 17,995

Target Family

Non-IDG 150 | 11,971
Enzyme 45 | 4,146
Kinase 11 | 634
Transporter 10 | 473
Ion Channel 4 | 341
GPCR 3 | 406
Epigenetic 1 | 242
Transcription Factor 1 | 1,400

Compartment GO Term

Late endosome 225 | 225
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Charged multivesicular body protein 2b CHMP2B Tbio Non-IDG -1.65708 53.0 166
Equilibrative nucleoside transporter 3 SLC29A3 Tbio Transporter -2.36515 247.3 58
Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 Tclin Ion Channel -2.92762 876.7 339
Ras-related protein Rab-11A RAB11A Tbio Enzyme -2.60207 398.9 288
Ankyrin repeat domain-containing protein 13D ANKRD13D Tdark Non-IDG 0.00000 36
Ras-related protein Rab-14 RAB14 Tbio Enzyme -1.40555 28.2 91
H(+)/Cl(-) exchange transporter 4 CLCN4 Tbio Ion Channel -1.48227 31.6 116
Ras-related protein Rab-27A RAB27A Tbio Enzyme -2.22946 184.9 247
Serotransferrin TF Tchem Non-IDG -4.13136 13124.3 952
Transferrin receptor protein 1 TFRC Tbio Non-IDG -3.39868 2437.0 1167