Development Level

Tbio 72 | 11,445
Tdark 45 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 10 | 979
embryonic lethality prior to o... 6 | 239
embryonic lethality prior to t... 4 | 278
abnormal embryo size 3 | 220
embryonic growth retardation 3 | 106
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal spleen morphology 1 | 55
abnormal tail morphology 1 | 25
decreased circulating glucose ... 1 | 126
decreased vertical activity 1 | 208
enlarged heart 1 | 210
enlarged spleen 1 | 41
impaired pupillary reflex 1 | 26
increased fasted circulating g... 1 | 76
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97

Disease

ovarian cancer 57 | 8,520
osteosarcoma 31 | 7,950
Carcinoma 29 | 11,493
lung cancer 28 | 4,740
Multiple myeloma 22 | 1,332
medulloblastoma, large-cell 19 | 6,241
Breast cancer 18 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,962
diabetes mellitus 15 | 1,728
group 3 medulloblastoma 15 | 4,104
psoriasis 15 | 6,694
non-small cell lung cancer 13 | 2,890
Waldenstrons macroglobulinemia 12 | 765
glioblastoma 11 | 5,792
acute myeloid leukemia 10 | 783
atypical teratoid / rhabdoid tumor 10 | 5,112
colon cancer 10 | 1,478
lung adenocarcinoma 10 | 2,716
Diamond-Blackfan anemia 9 | 31
non primary Sjogren syndrome sicca 9 | 891
sonic hedgehog group medulloblastoma 9 | 467
astrocytic glioma 8 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
malignant mesothelioma 7 | 3,232
Breast Neoplasms 6 | 445
Mammary Neoplasms 6 | 425
acute quadriplegic myopathy 6 | 1,158
dermatomyositis 6 | 966
invasive ductal carcinoma 6 | 2,951
oligodendroglioma 6 | 2,850
adult high grade glioma 5 | 3,801
ependymoma 5 | 4,679
group 4 medulloblastoma 5 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
pediatric high grade glioma 5 | 1,064
Adenocarcinoma of lung 4 | 142
Cleft Palate 4 | 271
Disease Models, Animal 4 | 155
Disease Progression 4 | 136
Intellectual disability 4 | 1,016
Kidney cancer 4 | 2,613
Retinitis pigmentosa 4 4 | 38
Stomach Neoplasms 4 | 300
active Crohn's disease 4 | 922
cystic fibrosis 4 | 1,696
hereditary spastic paraplegia 4 | 318
subependymal giant cell astrocytoma 4 | 2,287
Abnormality of the urinary system 3 | 21
Anemia 3 | 365
Anemia, Diamond-Blackfan 3 | 16
Anemia, Macrocytic 3 | 18
Cardiac Arrhythmia 3 | 103
Cardiac conduction abnormalities 3 | 78
Cardiovascular system disease 3 | 246
Conduction disorder of the heart 3 | 79
Delayed Puberty 3 | 97
EKG abnormalities 3 | 78
Electrocardiogram abnormal 3 | 81
Electrocardiogram change 3 | 78
Fatigue 3 | 182
Hand deformities 3 | 32
Intermittent migraine headaches 3 | 68
Lacrimal gland carcinoma 3 | 4
Migraine Disorders 3 | 76
Pallor 3 | 40
Pick disease 3 | 1,894
Shwachman-Diamond syndrome 3 | 17
Uranostaphyloschisis 3 | 167
astrocytoma 3 | 1,146
breast carcinoma 3 | 1,638
genital abnormal 3 | 17
nasopharyngeal carcinoma 3 | 1,058
primitive neuroectodermal tumor 3 | 3,035
reproductive system abnormality 3 | 17
tuberculosis and treatment for 6 months 3 | 409
ulcerative colitis 3 | 1,819
Becker muscular dystrophy 2 | 191
Cancer 2 | 2,499
Duchenne muscular dystrophy 2 | 601
Elevated hepatic transaminases 2 | 81
Essential Hypertension 2 | 94
Failure to gain weight 2 | 365
Fusariosis 2 | 6
Hepatic enzyme increased 2 | 81
Hepatomegaly 2 | 285
Liver Dysfunction 2 | 99
Liver enzymes abnormal 2 | 81
Liver function test increased 2 | 81
Liver function tests abnormal finding 2 | 81
Melanoma 2 | 711
Neurodegenerative disease 2 | 414
Osteoarthritis 2 | 184
Osteoporosis 2 | 363
Pediatric failure to thrive 2 | 365
Schizophrenia 2 | 1,160
Subclinical abnormal liver function tests 2 | 81
Transaminases increased 2 | 81
adrenocortical carcinoma 2 | 1,428
mucosa-associated lymphoid tissue lymphoma 2 | 484

Tissue

Digestive Tract 114 | 17,369
Endocrine System 114 | 18,159
Skin and soft tissues 114 | 17,230
Blood and immune system 113 | 16,909
Cardiovascular System 113 | 15,192
Female tissues 113 | 17,400
Liver and Pancreas 113 | 16,750
Male tissues 113 | 17,142
Nervous System 113 | 16,725
Respiratory system 113 | 16,393
Urinary Tract 113 | 16,678

Target Family

Non-IDG 109 | 12,091
Enzyme 8 | 4,145
Epigenetic 1 | 242

Compartment GO Term

Large ribosomal subunit 118 | 118
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
60S ribosomal protein L3 RPL3 Tbio Non-IDG -2.02901 103.9 190
60S ribosomal protein L36 RPL36 Tbio Non-IDG -1.62928 39.9 123
DNA-directed RNA polymerase II subunit RPB2 POLR2B Tbio Enzyme -2.49730 299.8 149
Ribosomal biogenesis protein LAS1L LAS1L Tdark Non-IDG -0.48801 2.91 109
39S ribosomal protein L22, mitochondrial MRPL22 Tdark Non-IDG 0.70 0.21 64
Uncharacterized protein C2orf15 C2orf15 Tdark Non-IDG 1.32 0.05 16
39S ribosomal protein L45, mitochondrial MRPL45 Tdark Non-IDG 0.51 0.23 0
39S ribosomal protein L49, mitochondrial MRPL49 Tbio Non-IDG -2.76367 555.1 76
39S ribosomal protein L11, mitochondrial MRPL11 Tdark Non-IDG -0.63555 3.41 198
Ribosome maturation protein SBDS SBDS Tbio Non-IDG -2.24233 174.4 139