Development Level

Tbio 4 | 11,445
Tchem 1 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

abnormal cranium morphology 1 | 36
abnormal incisor morphology 1 | 4
abnormal radius morphology 1 | 8
abnormal snout morphology 1 | 23
abnormal tooth morphology 1 | 24
abnormal ulna morphology 1 | 8
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased total body fat amoun... 1 | 207
increased blood urea nitrogen ... 1 | 48
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 5 | 11,493
Breast cancer 4 | 3,578
atypical teratoid / rhabdoid tumor 4 | 5,112
lung carcinoma 4 | 2,843
malignant mesothelioma 4 | 3,232
primary pancreatic ductal adenocarcinoma 4 | 1,109
psoriasis 4 | 6,694
Liver Cirrhosis, Experimental 3 | 769
Pulmonary emphysema 3 | 48
ependymoma 3 | 4,679
glioblastoma 3 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
osteosarcoma 3 | 7,950
ovarian cancer 3 | 8,520
pancreatic cancer 3 | 2,398
Acquired scoliosis 2 | 281
Acromicric Dysplasia 2 | 5
Aortic Valve Insufficiency 2 | 40
Astrocytoma, Pilocytic 2 | 3,081
Broad flat nasal bridge 2 | 236
Class III malocclusion 2 | 78
Coronary artery disease 2 | 268
Curvature of spine 2 | 282
Cutis Laxa 2 | 39
Decreased joint mobility 2 | 53
Decreased subcutaneous adipose tissue 2 | 13
Duchenne muscular dystrophy 2 | 601
Generalized elastolysis 2 | 24
Hanging skin 2 | 24
Heart disease 2 | 306
Hydronephrosis 2 | 89
Hyperglycemia 2 | 137
Hypertensive disease 2 | 292
Hypertrophy of lower jaw 2 | 78
Hypoplastic mandible condyle 2 | 275
Hypotrophic malar bone 2 | 129
Increased size of mandible 2 | 78
Liver Cirrhosis 2 | 181
Long philtrum 2 | 137
Malar flattening 2 | 129
Mandibular hyperplasia 2 | 78
Mandibular hypoplasia 2 | 275
Micrognathism 2 | 275
Muscular Dystrophy, Duchenne 2 | 7
Nasal bridge wide 2 | 236
Orbital separation excessive 2 | 244
Retrognathia 2 | 54
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
gastric carcinoma 2 | 807
interstitial cystitis 2 | 2,312
invasive ductal carcinoma 2 | 2,951
mandibular excess (physical finding) 2 | 78
medulloblastoma 2 | 720
pituitary cancer 2 | 1,972
ulcerative colitis 2 | 1,819
Abnormality of position of teeth 1 | 8
Aneurysm of ascending aorta 1 | 5
Aortic Aneurysm, Thoracic 1 | 8
Aortic valve stenosis 1 | 28
Broad ribs 1 | 12
Bronchomalacia 1 | 7
Bullet vertebral body 1 | 17
Camurati-Engelmann Syndrome 1 | 5
Camurati-Engelmann disease 1 | 6
Copper-Overload Cirrhosis 1 | 11
Depressive Symptoms 1 | 28
Diffusely thickened skin 1 | 20
Dry Eye Syndromes 1 | 8
Eyebrow abnormalities 1 | 12
Hammer Toe 1 | 23
Heart murmur 1 | 5
HyperCalcification of skull base 1 | 5
HyperMineralization of skull base 1 | 5
Hypoplasia of iris 1 | 10
Lipoatrophy 1 | 19
Liver Cirrhosis, Alcoholic 1 | 16
Marfan Syndrome 1 | 15
Misalignment of teeth 1 | 8
Narrow palate 1 | 20
Osteoporosis, Postmenopausal 1 | 6
Ovoid vertebral bodies 1 | 17
Pachyderma 1 | 20
Pain in limb 1 | 2
Pleural Diseases 1 | 10
Premature osteoarthritis 1 | 6
Proportionate short stature 1 | 4
Protrusio acetabuli 1 | 7
Sclerosis of skull base 1 | 5
Severe myopia 1 | 22
Shallow anterior chamber of eye 1 | 4
Short phalanx of finger 1 | 32
Spade-like hand 1 | 16
Spinal canal stenosis 1 | 12
Spondylolisthesis 1 | 22
Stiff skin 1 | 3
Talipes Calcaneovarus 1 | 2
Thoracic aortic aneurysm 1 | 15
Tracheal stenosis 1 | 23
Tricuspid valve insufficiency 1 | 14

Tissue

Blood and immune system 6 | 16,909
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678
Cardiovascular System 5 | 15,192
Respiratory system 5 | 16,393

Target Family

Non-IDG 6 | 12,091

Compartment GO Term

Large latent transforming grow... 6 | 6
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Latent-transforming growth factor beta-binding protein 1 LTBP1 Tbio Non-IDG -1.97590 101.5 128
Latent-transforming growth factor beta-binding protein 4 LTBP4 Tbio Non-IDG -1.55113 39.1 57
Fibrillin-1 FBN1 Tbio Non-IDG -3.08679 1236.3 325
POU domain, class 5, transcription factor 2 POU5F2 Tdark Non-IDG -0.62325 3.81 101
C-C motif chemokine 27 CCL27 Tbio Non-IDG -2.72180 519.6 214
Transforming growth factor beta-1 TGFB1 Tchem Non-IDG -3.84680 5672.0 1222