Development Level

Tbio 14 | 11,445
Tdark 1 | 6,588

IMPC Phenotype

abnormal embryo size 1 | 220
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
impaired glucose tolerance 1 | 75
increased blood urea nitrogen ... 1 | 48
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating phosphat... 1 | 26
increased circulating triglyce... 1 | 42
increased large unstained cell... 1 | 5
increased neutrophil cell numb... 1 | 46
increased red blood cell distr... 1 | 34
persistence of hyaloid vascula... 1 | 33
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 13 | 11,493
Kidney cancer 11 | 2,613
psoriasis 11 | 6,694
Breast cancer 10 | 3,578
ependymoma 10 | 4,679
atypical teratoid / rhabdoid tumor 9 | 5,112
ovarian cancer 9 | 8,520
Astrocytoma, Pilocytic 8 | 3,081
Liver cancer 8 | 604
glioblastoma 8 | 5,792
interstitial cystitis 8 | 2,312
malignant mesothelioma 8 | 3,232
osteosarcoma 7 | 7,950
Autosomal recessive predisposition 6 | 1,442
adult high grade glioma 6 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
lung adenocarcinoma 6 | 2,716
Kidney disease 5 | 430
astrocytic glioma 5 | 2,597
cutaneous lupus erythematosus 5 | 1,057
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
invasive ductal carcinoma 5 | 2,951
lung cancer 5 | 4,740
non-small cell lung cancer 5 | 2,890
oligodendroglioma 5 | 2,850
pituitary cancer 5 | 1,972
Bullous pemphigoid 4 | 18
Corneal erosion 4 | 16
Duchenne muscular dystrophy 4 | 601
Endometrial cancer 4 | 311
Epidermolysis bullosa 4 | 21
Fraser syndrome 4 | 13
Pick disease 4 | 1,894
Renal agenesis 4 | 29
Syndactyly 4 | 88
acute quadriplegic myopathy 4 | 1,158
dermatomyositis 4 | 966
diabetes mellitus 4 | 1,728
ductal carcinoma in situ 4 | 1,745
group 3 medulloblastoma 4 | 4,104
medulloblastoma, large-cell 4 | 6,241
nasopharyngeal carcinoma 4 | 1,058
pancreatic cancer 4 | 2,398
primitive neuroectodermal tumor 4 | 3,035
tuberculosis 4 | 2,010
Alport syndrome 3 | 21
Anemia 3 | 365
Arthritis 3 | 290
Atrophic scar 3 | 18
Cancer 3 | 2,499
Cataract 3 | 297
Dental caries 3 | 164
Down syndrome 3 | 499
Goodpasture syndrome 3 | 6
Herpes gestationis 3 | 6
Large intestine cancer 3 | 126
Lens Opacities 3 | 231
Melanoma 3 | 711
Myopia 3 | 176
Neuropathy 3 | 261
Osteoporosis 3 | 363
Rheumatoid arthritis 3 | 1,191
Skin cancer 3 | 469
Unilateral agenesis of kidney 3 | 20
adrenocortical carcinoma 3 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
breast carcinoma 3 | 1,638
gastric carcinoma 3 | 807
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
juvenile dermatomyositis 3 | 1,187
lung carcinoma 3 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
ulcerative colitis 3 | 1,819
Allergic hypersensitivity disease 2 | 126
Amyotrophic lateral sclerosis 2 | 451
Congenital clubfoot 2 | 109
Contracture 2 | 96
Contracture of joint 2 | 93
Dermatitis 2 | 157
Flexion contracture 2 | 93
Flexion contractures of joints 2 | 93
Heart disease 2 | 306
Hemoglobin low 2 | 124
Hypereosinophilic syndrome 2 | 71
Hypersensitivity reaction type II disease 2 | 253
Inflammatory bowel disease 2 | 151
Liver Cirrhosis, Experimental 2 | 769
Microstomia 2 | 78
Neurodegenerative disease 2 | 414
Polycystic ovary syndrome 2 | 360
Progressive disorder 2 | 142
Proteinuria 2 | 144
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
cystic fibrosis 2 | 1,696
cystic fibrosis and chronic rhinosinusitis 2 | 214
head and neck cancer 2 | 271
hepatocellular carcinoma 2 | 547
pediatric high grade glioma 2 | 1,064
progressive supranuclear palsy 2 | 676

Tissue

Endocrine System 15 | 18,159
Nervous System 15 | 16,725
Respiratory system 15 | 16,393
Blood and immune system 14 | 16,909
Digestive Tract 14 | 17,369
Female tissues 14 | 17,400
Liver and Pancreas 14 | 16,750
Male tissues 14 | 17,142
Skin and soft tissues 14 | 17,230
Urinary Tract 14 | 16,678
Cardiovascular System 12 | 15,192

Target Family

Non-IDG 13 | 12,091
Enzyme 2 | 4,145

Compartment GO Term

Lamina densa 15 | 15
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Extracellular matrix protein FRAS1 FRAS1 Tbio Non-IDG -1.51346 36.5 22
Collagen alpha-1(XVII) chain COL17A1 Tbio Non-IDG -2.75473 576.3 123
Nidogen-1 NID1 Tbio Non-IDG -2.80605 647.4 267
FRAS1-related extracellular matrix protein 3 FREM3 Tdark Non-IDG -0.70138 3.98 3
E3 ubiquitin-protein ligase RNF103 RNF103 Tbio Enzyme -1.95102 35.6 76
Nidogen-2 NID2 Tbio Non-IDG -1.62355 40.1 116
Dystonin DST Tbio Non-IDG -2.73231 506.0 127
FRAS1-related extracellular matrix protein 2 FREM2 Tbio Non-IDG -1.25766 15.5 77
FRAS1-related extracellular matrix protein 1 FREM1 Tbio Non-IDG -1.43010 27.7 61
Collagen alpha-3(IV) chain COL4A3 Tbio Non-IDG -2.32017 204.4 209