Development Level

Tbio 4 | 11,445

IMPC Phenotype

abnormal heart morphology 1 | 162
abnormal liver morphology 1 | 17
abnormal spleen morphology 1 | 55
decreased vertical activity 1 | 208
enlarged heart 1 | 210
enlarged spleen 1 | 41
hydrometra 1 | 53
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 4 | 11,493
psoriasis 4 | 6,694
Congenital ichthyosiform erythroderma 3 | 28
lung adenocarcinoma 3 | 2,716
lung carcinoma 3 | 2,843
Autosomal recessive predisposition 2 | 1,442
Breast cancer 2 | 3,578
Colorectal Neoplasms 2 | 243
Failure to gain weight 2 | 365
Kidney cancer 2 | 2,613
Palmoplantar keratosis 2 | 74
Pediatric failure to thrive 2 | 365
Skin cancer 2 | 469
Tangier disease 2 | 10
adult high grade glioma 2 | 3,801
glioblastoma 2 | 5,792
lung cancer 2 | 4,740
malignant mesothelioma 2 | 3,232
non-small cell lung cancer 2 | 2,890
osteosarcoma 2 | 7,950
ovarian cancer 2 | 8,520
ulcerative colitis 2 | 1,819
Abnormal helices 1 | 11
Abnormality of the abdomen 1 | 14
Absence of eyebrows 1 | 31
Alopecia 1 | 115
Aplasia/Hypoplasia of the eyebrow 1 | 31
Atopic dermatitis 1 | 952
Autosomal recessive congenital ichthyosis 1 1 | 3
Autosomal recessive congenital ichthyosis 4B 1 | 13
CEDNIK syndrome 1 | 3
Clouston syndrome 1 | 9
Congenital deafness 1 | 185
Congenital neurologic anomalies 1 | 20
Corneal erosion 1 | 16
Deafness 1 | 198
Decreased joint mobility 1 | 53
Desquamative interstitial pneumonia 1 | 4
Dry skin 1 | 75
Ectropion 1 | 38
Emphysema 1 | 12
Endometrial cancer 1 | 311
Entropion 1 | 22
Everted lower lip vermilion 1 | 54
Exfoliative dermatitis 1 | 24
Exophthalmos 1 | 112
Hearing Loss, Partial 1 | 185
Hearing abnormality 1 | 12
Hyperkeratosis 1 | 50
Hypertension, Pulmonary 1 | 37
Hypohidrosis 1 | 34
Hypoplastic finger 1 | 17
Hypotrichosis 1 | 47
Ichthyoses 1 | 41
Ichthyosis 1 | 56
Influenza 1 | 142
Influenza, Human 1 | 51
Interstitial lung disease due to ABCA3 deficiency 1 | 1
Keratitis 1 | 62
Lack of skin elasticity 1 | 10
MEDNIK syndrome 1 | 8
Melanoma 1 | 711
Multiple Sclerosis 1 | 540
Muscle Rigidity 1 | 49
Nail Diseases 1 | 24
Nail abnormality 1 | 22
Nonsyndromic deafness 1 | 142
Oculodentodigital dysplasia 1 | 14
Pneumonia 1 | 174
Premature Birth 1 | 77
Premature birth of newborn 1 | 67
Prenatal onset 1 | 139
Prominent eyes 1 | 96
Prominent globes 1 | 96
Protruding eyes 1 | 96
Protruding lower lip 1 | 54
Pruritus 1 | 58
Pulmonary Fibrosis 1 | 106
Pulmonary Fibrosis, Idiopathic 1 | 12
Pulmonary alveolar proteinosis 1 | 15
Recurrent respiratory infections 1 | 141
Respiratory Failure 1 | 104
Respiratory distress 1 | 43
Sensorineural hearing loss 1 | 106
Short finger 1 | 17
Skin disease 1 | 66
Sparse hair 1 | 59
Sparse or absent eyebrows 1 | 31
Sparse/absent eyebrows 1 | 31
Stretched skin 1 | 10
Surfactant Metabolism Dysfunction, Pulmonary, 3 1 | 1
Tachypnea 1 | 20
Thin, sparse hair 1 | 59
Xerosis 1 | 75
active Crohn's disease 1 | 922
hearing impairment 1 | 199
interstitial lung disease 1 | 298
non-small cell lung carcinoma 1 | 317
pediatric high grade glioma 1 | 1,064
tuberculosis 1 | 2,010

Tissue

Blood and immune system 4 | 16,909
Digestive Tract 4 | 17,369
Endocrine System 4 | 18,159
Female tissues 4 | 17,400
Male tissues 4 | 17,142
Skin and soft tissues 4 | 17,230
Urinary Tract 4 | 16,678
Liver and Pancreas 3 | 16,750
Nervous System 3 | 16,725
Cardiovascular System 2 | 15,192
Respiratory system 2 | 16,393

Target Family

Non-IDG 2 | 12,091
Transporter 2 | 473

Compartment GO Term

Lamellar body membrane 4 | 4
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ATP-binding cassette sub-family A member 3 ABCA3 Tbio Transporter -2.25972 187.7 32
ATP-binding cassette sub-family A member 12 ABCA12 Tbio Transporter -2.05873 115.5 66
Gap junction beta-4 protein GJB4 Tbio Non-IDG -1.60100 40.2 125
Lysosome-associated membrane glycoprotein 3 LAMP3 Tbio Non-IDG -1.74174 56.1 382