Development Level

Tbio 12 | 11,445
Tchem 3 | 1,598

IMPC Phenotype

abnormal behavior 1 | 298
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
hypoactivity 1 | 132
prenatal lethality prior to he... 1 | 87

Disease

Carcinoma 10 | 11,493
ovarian cancer 7 | 8,520
glioblastoma 6 | 5,792
psoriasis 6 | 6,694
Cancer 5 | 2,499
atypical teratoid / rhabdoid tumor 5 | 5,112
osteosarcoma 5 | 7,950
dermatomyositis 4 | 966
ependymoma 4 | 4,679
group 3 medulloblastoma 4 | 4,104
juvenile dermatomyositis 4 | 1,187
lung cancer 4 | 4,740
oligodendroglioma 4 | 2,850
primitive neuroectodermal tumor 4 | 3,035
Anemia 3 | 365
Autosomal recessive predisposition 3 | 1,442
Hyperhidrosis disorder 3 | 81
Immunologic Deficiency Syndromes 3 | 113
Increased sweating 3 | 81
Kidney cancer 3 | 2,613
Lymphoma 3 | 81
Sweating 3 | 81
adult high grade glioma 3 | 3,801
astrocytic glioma 3 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
medulloblastoma, large-cell 3 | 6,241
tuberculosis 3 | 2,010
Astrocytoma, Pilocytic 2 | 3,081
B-Cell Lymphomas 2 | 12
Breast cancer 2 | 3,578
Carcinoma, Hepatocellular 2 | 228
Constipation 2 | 181
Dermatitis 2 | 157
Diffuse large B-cell lymphoma 2 | 39
Dyschezia 2 | 135
Edwards syndrome 2 | 17
Eosinophilia 2 | 28
Epilepsy 2 | 792
Familial primary gastric lymphoma 2 | 4
Fatigue 2 | 182
Fever 2 | 138
Gastric lymphoma 2 | 7
Growth delay 2 | 114
Growth failure 2 | 114
Growth retardation 2 | 115
Hemoglobin low 2 | 124
Increased susceptibility to bacterial infections 2 | 42
Infiltrate of lung 2 | 17
Liver carcinoma 2 | 240
Lymphoma, Large B-Cell, Diffuse 2 | 34
MALT lymphoma 2 | 6
Multiple myeloma 2 | 1,332
Nausea and vomiting 2 | 97
POLYGLUCOSAN BODY MYOPATHY 1 WITH OR WITHOUT IMMUNODEFICIENCY 2 | 2
Pick disease 2 | 1,894
Poor growth 2 | 114
Prone to bacterial infection 2 | 42
Recurrent bacterial infection 2 | 42
Recurrent infections 2 | 48
Seizures 2 | 596
Skin cancer 2 | 469
Telangiectasia of the skin 2 | 39
Very poor growth 2 | 114
Weight decreased 2 | 103
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
malignant mesothelioma 2 | 3,232
mucosa-associated lymphoid tissue lymphoma 2 | 484
non primary Sjogren syndrome sicca 2 | 891
pancreatic cancer 2 | 2,398
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis and treatment for 6 months 2 | 409
Abnormal pigmentation 1 | 25
Accessory nipple 1 | 11
Accessory rib 1 | 10
Acquired deformity of finger 1 | 3
Cleft palate with cleft lip 1 | 23
Congenital absence of breast 1 | 1
Congenital hemivertebra 1 | 25
Congenital hypoplasia of breast 1 | 25
Dental abnormalities 1 | 60
Ectodermal Dysplasia, Anhidrotic, with Immunodeficiency, Osteopetrosis, and Lymphedema 1 | 1
Ectodermal dysplasia, hypohidrotic, with immune deficiency 1 | 2
Fine hair 1 | 42
Hyperkeratosis 1 | 50
Hypoplasia of nipple 1 | 16
Hypoplastic fingernails 1 | 11
INVASIVE PNEUMOCOCCAL DISEASE, RECURRENT ISOLATED, 2 (disorder) 1 | 1
IgG Deficiency 1 | 22
Immunodeficiency without anhidrotic ectodermal dysplasia 1 | 1
Immunoglobulin A deficiency (disorder) 1 | 19
Increased IgM levels 1 | 16
Kyphoscoliosis deformity of spine 1 | 60
Lymphatic obstruction 1 | 21
Onset of lymphedema around puberty 1 | 21
Onychogryposis 1 | 13
Peg-shaped incisors 1 | 6
Recurrent mycobacterium avium complex infections 1 | 2
Ridged nails 1 | 14
X- linked recessive 1 | 110
hypopigmented skin patch 1 | 59

Tissue

Blood and immune system 15 | 16,909
Cardiovascular System 15 | 15,192
Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Liver and Pancreas 15 | 16,750
Male tissues 15 | 17,142
Nervous System 15 | 16,725
Respiratory system 15 | 16,393
Skin and soft tissues 15 | 17,230
Urinary Tract 15 | 16,678

Target Family

Non-IDG 8 | 12,091
Enzyme 5 | 4,145
Kinase 2 | 634

Compartment GO Term

LUBAC complex 15 | 15
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Iron-responsive element-binding protein 2 IREB2 Tbio Non-IDG -2.33609 211.7 253
Granzyme M GZMM Tbio Enzyme -2.65427 401.1 77
Caspase recruitment domain-containing protein 11 CARD11 Tbio Enzyme -2.17228 139.2 235
Baculoviral IAP repeat-containing protein 2 BIRC2 Tchem Non-IDG -2.53423 308.7 351
RanBP-type and C3HC4-type zinc finger-containing protein 1 RBCK1 Tbio Non-IDG -1.58319 39.4 224
Receptor-interacting serine/threonine-protein kinase 1 RIPK1 Tchem Kinase -2.33991 211.8 375
B-cell lymphoma/leukemia 10 BCL10 Tbio Non-IDG -0.53932 4.30 895
NF-kappa-B essential modulator IKBKG Tbio Kinase -3.07452 1188.4 879
Spermatogenesis-associated protein 2 SPATA2 Tbio Non-IDG -0.87658 8.15 125
Ubiquitin D UBD Tbio Non-IDG -2.35231 223.1 210