Development Level

Tbio 12 | 10,625
Tchem 3 | 1,890

Disease

glioblastoma 6 | 5,572
osteosarcoma 6 | 7,933
ovarian cancer 6 | 8,491
atypical teratoid / rhabdoid tumor 5 | 4,369
psoriasis 5 | 6,685
astrocytic glioma 4 | 2,241
lung cancer 4 | 4,473
malignant mesothelioma 4 | 3,163
oligodendroglioma 4 | 2,849
primitive neuroectodermal tumor 4 | 3,031
Cancer 3 | 2,346
Carcinoma 3 | 2,147
Crohn's disease 3 | 304
Lymphoma 3 | 57
dermatomyositis 3 | 966
ependymoma 3 | 2,514
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
juvenile dermatomyositis 3 | 1,189
medulloblastoma, large-cell 3 | 6,234
tuberculosis and treatment for 6 months 3 | 686
Dermatitis 2 | 141
Diffuse large B-cell lymphoma 2 | 42
Edwards syndrome 2 | 15
Leprosy 2 | 77
Liver carcinoma 2 | 217
MALT lymphoma 2 | 5
Pick disease 2 | 1,893
Polyglucosan body myopathy 1 with or without immunodeficiency 2 | 2
Sezary Syndrome 2 | 26
acute myeloid leukemia 2 | 785
gastric cancer 2 | 436
group 3 medulloblastoma 2 | 2,254
hepatocellular carcinoma 2 | 550
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,289
medulloblastoma 2 | 1,524
non primary Sjogren syndrome sicca 2 | 840
pancreatic cancer 2 | 2,300
pediatric high grade glioma 2 | 2,712
posterior fossa group A ependymoma 2 | 1,511
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 1,563
ATYPICAL MYCOBACTERIOSIS, FAMILIAL, X-LINKED 1 (disorder) 1 | 1
Adult T-Cell Lymphoma/Leukemia 1 | 30
Anemia 1 | 252
Anhidrotic ectodermal dysplasia-immunodeficiency-osteopetrosis-lymphedema syndrome 1 | 1
Autistic Disorder 1 | 320
Bloch Sulzberger syndrome 1 | 1
Bloch-Sulzberger syndrome 1 | 2
Carcinoma of colon 1 | 32
Cardiomegaly 1 | 66
Celiac disease 1 | 112
Cleft Lip 1 | 91
Cleft palate 1 | 125
Colon Carcinoma 1 | 25
Depersonalization disorder 1 | 4
Ectodermal Dysplasia, Anhidrotic, with Immunodeficiency, Osteopetrosis, and Lymphedema 1 | 1
Ectodermal dysplasia, anhidrotic, with immunodeficiency X-linked 1 | 1
Ectodermal dysplasia, anhidrotic, with immunodeficiency, osteopetrosis and lymphedema 1 | 1
Ectodermal dysplasia, hypohidrotic, with immune deficiency 1 | 1
FL1 1 | 1
Gaucher disease type 3 1 | 76
Glycogen storage disease 1 | 37
Hepatitis B 1 | 103
Hypohidrotic ectodermal dysplasia 1 | 14
Hypohidrotic ectodermal dysplasia with immunodeficiency 1 | 2
INVASIVE PNEUMOCOCCAL DISEASE, RECURRENT ISOLATED, 2 (disorder) 1 | 1
Immune system cancer 1 | 38
Immunodeficiency 33 1 | 1
Immunodeficiency 37 1 | 1
Immunodeficiency without anhidrotic ectodermal dysplasia 1 | 1
Immunodeficiency, NEMO-related, without anhidrotic ectodermal dysplasia 1 | 1
Incontinentia pigmenti 1 | 1
Incontinentia pigmenti syndrome 1 | 1
Incontinentia pigmenti, familial male-lethal type 1 | 1
Invasive pneumococcal disease, recurrent isolated, 2 1 | 1
Lung Neoplasms 1 | 171
Lupus Erythematosus, Systemic 1 | 73
Lymphedema 1 | 26
Lymphoma, Follicular 1 | 20
Lymphoma, T-Cell, Cutaneous 1 | 21
Malignant lymphoma, non-Hodgkin 1 | 4
Malignant neoplasm of testis 1 | 5
Mesothelioma 1 | 40
Neoplasm Invasiveness 1 | 127
Non-alcoholic Fatty Liver Disease 1 | 40
Osteopetrosis 1 | 40
Pancreatic acinar cell adenocarcinoma 1 | 2
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1 | 18
Primary immunodeficiency disease 1 | 52
Proteinuria 1 | 63
Recurrent isolated invasive pneumococcal disease 2 1 | 1
Renal Cell Carcinoma 1 | 199
Sebaceous adenoma 1 | 11
Skin disease 1 | 65
Subdural empyema 1 | 7
Tactile agnosia 1 | 3
Testicular germ cell tumor 1 | 23
Tooth agenesis 1 | 38
substance-related disorder 1 | 104
systemic lupus erythematosus 1 | 172

Tissue

Blood and immune system 15 | 17,994
Cardiovascular System 15 | 17,957
Digestive Tract 15 | 18,472
Endocrine System 15 | 18,511
Female tissues 15 | 18,646
Liver and Pancreas 15 | 18,135
Male tissues 15 | 17,968
Nervous System 15 | 18,560
Respiratory system 15 | 17,483
Urinary Tract 15 | 18,443
Skin and soft tissues 14 | 18,114

Target Family

Non-IDG 8 | 11,969
Enzyme 5 | 4,146
Kinase 2 | 634

Compartment GO Term

LUBAC complex 15 | 15
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Granzyme M GZMM Tbio Enzyme -2.62966 380.8 62
Caspase recruitment domain-containing protein 11 CARD11 Tbio Enzyme -2.12968 129.2 231
Spermatogenesis-associated protein 2 SPATA2 Tbio Non-IDG -0.80505 6.47 109
Receptor-interacting serine/threonine-protein kinase 2 RIPK2 Tchem Kinase -2.00230 103.9 435
Ubiquitin carboxyl-terminal hydrolase CYLD CYLD Tbio Enzyme -2.90259 806.3 176
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 MALT1 Tchem Non-IDG -2.39284 241.6 397
Sharpin SHARPIN Tbio Non-IDG -1.26011 20.0 110
Ubiquitin D UBD Tbio Non-IDG -2.30198 210.8 181
E3 ubiquitin-protein ligase RNF31 RNF31 Tbio Enzyme -1.69637 52.4 155
Iron-responsive element-binding protein 2 IREB2 Tbio Non-IDG -2.30979 195.8 216