Development Level

Tbio 27 | 11,445
Tchem 4 | 1,598

IMPC Phenotype

preweaning lethality, complete... 6 | 979
cataract 2 | 92
embryonic lethality prior to o... 2 | 239
increased fasted circulating g... 2 | 76
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal lens morphology 1 | 81
abnormal motor learning 1 | 3
abnormal placenta morphology 1 | 5
abnormal placenta size 1 | 20
abnormal placenta vasculature 1 | 2
abnormal skin coloration 1 | 25
abnormal tail morphology 1 | 25
decreased circulating choleste... 1 | 93
decreased circulating serum al... 1 | 82
decreased heart left ventricle... 1 | 28
decreased total body fat amoun... 1 | 207
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating creatini... 1 | 38
increased circulating sodium l... 1 | 71
increased lean body mass 1 | 172
increased mean platelet volume 1 | 45
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
syndactyly 1 | 23

Disease

Carcinoma 25 | 11,493
medulloblastoma, large-cell 22 | 6,241
group 3 medulloblastoma 21 | 4,104
psoriasis 21 | 6,694
Breast cancer 20 | 3,578
atypical teratoid / rhabdoid tumor 20 | 5,112
glioblastoma 20 | 5,792
lung cancer 19 | 4,740
ovarian cancer 18 | 8,520
primitive neuroectodermal tumor 18 | 3,035
non-small cell lung cancer 17 | 2,890
adult high grade glioma 16 | 3,801
adrenocortical carcinoma 15 | 1,428
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,291
ependymoma 14 | 4,679
invasive ductal carcinoma 14 | 2,951
lung adenocarcinoma 13 | 2,716
osteosarcoma 13 | 7,950
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
nasopharyngeal carcinoma 12 | 1,058
Atopic dermatitis 11 | 952
Cancer 11 | 2,499
breast carcinoma 11 | 1,638
Endometriosis 10 | 540
ductal carcinoma in situ 10 | 1,745
malignant mesothelioma 10 | 3,232
Kidney cancer 8 | 2,613
colon cancer 8 | 1,478
pancreatic cancer 8 | 2,398
oligodendroglioma 6 | 2,850
Astrocytoma, Pilocytic 5 | 3,081
Hypoplastic mandible condyle 5 | 275
Intellectual disability 5 | 1,016
Mandibular hypoplasia 5 | 275
Micrognathism 5 | 275
Small head 5 | 374
interstitial cystitis 5 | 2,312
ulcerative colitis 5 | 1,819
Dull intelligence 4 | 645
Glaucoma 4 | 239
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Poor school performance 4 | 645
Short stature 4 | 531
active Crohn's disease 4 | 922
astrocytic glioma 4 | 2,597
pediatric high grade glioma 4 | 1,064
primary Sjogren syndrome 4 | 735
Abnormality of vision 3 | 40
Abnormally small eyeball 3 | 97
Acute poststreptococcal glomerulonephritis 3 | 5
Ascites 3 | 22
Autosomal recessive predisposition 3 | 1,442
Cataract 3 | 297
Cerebellar Hypoplasia 3 | 61
Clouding of corneal stroma 3 | 50
Cognitive delay 3 | 608
Congenital Epicanthus 3 | 177
Corneal Opacity 3 | 53
Dandy-Walker Syndrome 3 | 39
Decreased size of eyeball 3 | 97
Global developmental delay 3 | 608
Increased nuchal translucency 3 | 6
Lens Opacities 3 | 231
MOSAIC VARIEGATED ANEUPLOIDY SYNDROME 3 | 5
Mental and motor retardation 3 | 608
Microcephaly 3 | 166
Microphthalmos 3 | 100
Muscle biopsy shows dystrophic changes 3 | 39
Muscular dystrophy 3 | 75
Pick disease 3 | 1,894
Polyhydramnios 3 | 108
Rheumatic fever 3 | 19
Triangular face 3 | 58
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
mosaic variegated aneuploidy syndrome 1 3 | 4
pituitary cancer 3 | 1,972
Agenesis of corpus callosum 2 | 83
Bipolar Disorder 2 | 666
Carcinoma of colon 2 | 32
Cleft Palate 2 | 271
Fetal Growth Retardation 2 | 189
Hydrocephalus 2 | 152
Infant, Small for Gestational Age 2 | 176
Intrauterine retardation 2 | 176
Leukemia 2 | 104
Low set ears 2 | 181
Lymphoid leukemia 2 | 160
Orbital separation excessive 2 | 244
Renal Cell Carcinoma 2 | 214
Skin cancer 2 | 469
Stomach Neoplasms 2 | 300
Uranostaphyloschisis 2 | 167
astrocytoma 2 | 1,146
lung carcinoma 2 | 2,843
medulloblastoma 2 | 720
Cystic kidney 1 | 30
Renal cyst 1 | 30
Rhabdomyosarcoma 1 | 39

Tissue

Endocrine System 31 | 18,159
Blood and immune system 30 | 16,909
Digestive Tract 30 | 17,369
Female tissues 30 | 17,400
Liver and Pancreas 29 | 16,750
Male tissues 29 | 17,142
Nervous System 29 | 16,725
Respiratory system 29 | 16,393
Skin and soft tissues 29 | 17,230
Urinary Tract 29 | 16,678
Cardiovascular System 26 | 15,192

Target Family

Non-IDG 26 | 12,091
Kinase 4 | 634
Enzyme 1 | 4,145

Compartment GO Term

Kinetochore microtubule 31 | 31
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Calcium and integrin-binding family member 3 CIB3 Tbio Non-IDG -1.23394 14.1 101
Kinesin-like protein KIF2C KIF2C Tbio Non-IDG -2.12404 136.3 256
Spindle and kinetochore-associated protein 2 SKA2 Tbio Non-IDG -1.23206 10.2 108
Centromere protein F CENPF Tbio Non-IDG -2.02939 109.1 186
Shugoshin 1 SGO1 Tbio Non-IDG -2.44224 279.8 148
Kinesin-like protein KIF18A KIF18A Tbio Non-IDG -1.46205 32.3 88
Kinetochore scaffold 1 KNL1 Tbio Non-IDG -2.20924 151.8 85
Spindle and kinetochore-associated protein 1 SKA1 Tbio Non-IDG -1.50228 32.0 58
Centromere-associated protein E CENPE Tchem Non-IDG -2.14817 140.2 166
Centromere protein T CENPT Tbio Non-IDG -1.19511 14.4 69