Development Level

Tbio 114 | 11,445
Tchem 17 | 1,598
Tdark 13 | 6,588

IMPC Phenotype

preweaning lethality, complete... 31 | 979
embryonic lethality prior to o... 8 | 239
embryonic lethality prior to t... 7 | 278
abnormal embryo size 4 | 220
abnormal tail morphology 4 | 25
cataract 4 | 92
increased circulating HDL chol... 4 | 80
abnormal lens morphology 3 | 81
abnormal seminal vesicle morph... 3 | 114
embryonic growth retardation 3 | 106
increased circulating alkaline... 3 | 122
preweaning lethality, incomple... 3 | 499
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
decreased circulating choleste... 2 | 93
decreased vertical activity 2 | 208
edema 2 | 59
enlarged lymph nodes 2 | 37
hemorrhage 2 | 23
impaired glucose tolerance 2 | 75
increased bone mineral content 2 | 108
increased circulating creatini... 2 | 38
increased fasted circulating g... 2 | 76
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
prolonged QT interval 2 | 38
prolonged ST segment 2 | 36
small testis 2 | 58
abnormal behavioral response t... 1 | 66
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal embryo turning 1 | 31
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal limb morphology 1 | 13
abnormal lung morphology 1 | 26
abnormal motor learning 1 | 3
abnormal placenta morphology 1 | 5
abnormal placenta size 1 | 20
abnormal placenta vasculature 1 | 2
abnormal retina morphology 1 | 71
abnormal retinal inner nuclear... 1 | 8
abnormal retinal outer nuclear... 1 | 3
abnormal skin coloration 1 | 25
abnormal sleep behavior 1 | 70
abnormal testis morphology 1 | 43
cardiovascular system phenotyp... 1 | 36
corneal opacity 1 | 32
cyanosis 1 | 7
decreased basophil cell number 1 | 16
decreased caudal vertebrae num... 1 | 53
decreased circulating chloride... 1 | 30
decreased circulating free fat... 1 | 31
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased hematocrit 1 | 46
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
decreased total retina thickne... 1 | 17
enlarged heart 1 | 210
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased circulating LDL chol... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating glucose ... 1 | 24
increased circulating sodium l... 1 | 71
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased mean platelet volume 1 | 45
increased or absent threshold ... 1 | 101
increased thermal nociceptive ... 1 | 9
irregularly shaped pupil 1 | 7
microphthalmia 1 | 26
mydriasis 1 | 6
prenatal lethality prior to he... 1 | 87
respiratory system phenotype 1 | 2
sclerocornea 1 | 2
small kidney 1 | 16
small spleen 1 | 19
syndactyly 1 | 23
thrombocytopenia 1 | 56
urinary bladder obstruction 1 | 4

Disease

ovarian cancer 96 | 8,520
Carcinoma 90 | 11,493
medulloblastoma, large-cell 83 | 6,241
group 3 medulloblastoma 80 | 4,104
psoriasis 79 | 6,694
glioblastoma 74 | 5,792
atypical teratoid / rhabdoid tumor 73 | 5,112
lung cancer 72 | 4,740
Breast cancer 71 | 3,578
osteosarcoma 67 | 7,950
primitive neuroectodermal tumor 64 | 3,035
non-small cell lung cancer 59 | 2,890
adrenocortical carcinoma 56 | 1,428
intraductal papillary-mucinous neoplasm (IPMN) 55 | 3,291
adult high grade glioma 52 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 52 | 2,989
ependymoma 49 | 4,679
invasive ductal carcinoma 47 | 2,951
malignant mesothelioma 47 | 3,232
lung adenocarcinoma 45 | 2,716
Cancer 37 | 2,499
colon cancer 35 | 1,478
ductal carcinoma in situ 35 | 1,745
Atopic dermatitis 33 | 952
Endometriosis 32 | 540
breast carcinoma 31 | 1,638
oligodendroglioma 31 | 2,850
pancreatic cancer 29 | 2,398
Kidney cancer 27 | 2,613
nasopharyngeal carcinoma 26 | 1,058
Astrocytoma, Pilocytic 21 | 3,081
astrocytic glioma 21 | 2,597
Multiple myeloma 19 | 1,332
Waldenstrons macroglobulinemia 19 | 765
ulcerative colitis 18 | 1,819
Pick disease 17 | 1,894
subependymal giant cell astrocytoma 17 | 2,287
Intellectual disability 16 | 1,016
primary Sjogren syndrome 16 | 735
interstitial cystitis 15 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
non primary Sjogren syndrome sicca 14 | 891
pediatric high grade glioma 14 | 1,064
dermatomyositis 13 | 966
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
pituitary cancer 12 | 1,972
tuberculosis 12 | 2,010
acute quadriplegic myopathy 11 | 1,158
astrocytoma 11 | 1,146
juvenile dermatomyositis 10 | 1,187
Cognitive delay 9 | 608
Epilepsy 9 | 792
Global developmental delay 9 | 608
Mental and motor retardation 9 | 608
Small head 9 | 374
esophageal adenocarcinoma 9 | 737
group 4 medulloblastoma 9 | 1,855
progressive supranuclear palsy 9 | 676
Dull intelligence 8 | 645
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Microcephaly 8 | 166
Poor school performance 8 | 645
Schizophrenia 8 | 1,160
Short stature 8 | 531
active Crohn's disease 8 | 922
lung carcinoma 8 | 2,843
posterior fossa group A ependymoma 8 | 468
Alzheimer's disease 7 | 658
Amyotrophic lateral sclerosis 7 | 451
Anteverted nostril 7 | 191
Hypoplastic mandible condyle 7 | 275
Mandibular hypoplasia 7 | 275
Micrognathism 7 | 275
Seizures 7 | 596
acute myeloid leukemia 7 | 783
medulloblastoma 7 | 720
Bipolar Disorder 6 | 666
Congenital Epicanthus 6 | 177
Rheumatoid arthritis 6 | 1,191
cutaneous lupus erythematosus 6 | 1,057
hereditary spastic paraplegia 6 | 318
Autosomal recessive predisposition 5 | 1,442
Cerebellar Hypoplasia 5 | 61
Down syndrome 5 | 499
Glaucoma 5 | 239
Lissencephaly 5 | 69
Liver cancer 5 | 604
Lymphoid leukemia 5 | 160
Melanoma 5 | 711
Stomach Neoplasms 5 | 300
gastric carcinoma 5 | 807
Depressed nasal bridge 4 | 195
Small nose 4 | 132
aldosterone-producing adenoma 4 | 665
gastric cancer 4 | 459
hepatocellular carcinoma 4 | 547
pancreatic carcinoma 4 | 562
primary pancreatic ductal adenocarcinoma 4 | 1,109

Tissue

Endocrine System 144 | 18,159
Blood and immune system 142 | 16,909
Digestive Tract 142 | 17,369
Female tissues 142 | 17,400
Liver and Pancreas 142 | 16,750
Male tissues 142 | 17,142
Nervous System 142 | 16,725
Respiratory system 142 | 16,393
Skin and soft tissues 142 | 17,230
Urinary Tract 142 | 16,678
Cardiovascular System 136 | 15,192

Target Family

Non-IDG 113 | 12,091
Enzyme 14 | 4,145
Kinase 11 | 634
Epigenetic 3 | 242
Transcription Factor 3 | 1,400

Compartment GO Term

Kinetochore 144 | 144
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
CAP-Gly domain-containing linker protein 1 CLIP1 Tbio Non-IDG -2.54943 343.7 221
Sperm-associated antigen 5 SPAG5 Tbio Non-IDG -1.72743 51.4 136
Nuclear distribution protein nudE homolog 1 NDE1 Tbio Non-IDG -2.01711 96.0 192
Mitotic spindle assembly checkpoint protein MAD1 MAD1L1 Tbio Non-IDG -1.17500 13.6 283
Transforming acidic coiled-coil-containing protein 3 TACC3 Tbio Non-IDG -1.99617 101.2 222
Spindle and kinetochore-associated protein 2 SKA2 Tbio Non-IDG -1.23206 10.2 108
Protein SGT1 homolog SUGT1 Tbio Non-IDG -0.79781 9.93 183
G patch domain-containing protein 11 GPATCH11 Tdark Non-IDG 0.14 0.15 105
Small kinetochore-associated protein KNSTRN Tbio Non-IDG -1.28291 21.4 32
Centromere protein K CENPK Tbio Non-IDG -1.21832 16.6 130