Development Level

Tbio 60 | 11,651
Tchem 6 | 1,388
Tdark 4 | 6,593

IMPC Phenotype

preweaning lethality, complete... 12 | 979
abnormal embryo size 5 | 220
cyanosis 2 | 7
embryonic growth retardation 2 | 106
hemorrhage 2 | 23
hyperactivity 2 | 148
increased mean corpuscular vol... 2 | 92
prenatal lethality prior to he... 2 | 87
prolonged QT interval 2 | 38
prolonged ST segment 2 | 36
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal facial morphology 1 | 17
abnormal head shape 1 | 10
abnormal limb morphology 1 | 13
abnormal outer ear morphology 1 | 3
abnormal skin coloration 1 | 25
abnormal sleep behavior 1 | 70
abnormal tail morphology 1 | 25
absent pinna reflex 1 | 23
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased bone mineral content 1 | 151
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating free fat... 1 | 31
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased heart left ventricle... 1 | 28
decreased lean body mass 1 | 135
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
embryonic lethality prior to t... 1 | 278
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating chloride... 1 | 41
increased circulating glucose ... 1 | 24
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased or absent threshold ... 1 | 101
persistence of hyaloid vascula... 1 | 33
premature death 1 | 5
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 64 | 11,493
medulloblastoma, large-cell 38 | 6,241
ovarian cancer 38 | 8,520
glioblastoma 36 | 5,792
atypical teratoid / rhabdoid tumor 35 | 5,112
osteosarcoma 32 | 7,950
psoriasis 32 | 6,694
group 3 medulloblastoma 31 | 4,104
lung cancer 30 | 4,740
adult high grade glioma 29 | 3,801
Breast cancer 25 | 3,578
ependymoma 25 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,989
primitive neuroectodermal tumor 22 | 3,035
malignant mesothelioma 21 | 3,232
non-small cell lung cancer 21 | 2,890
invasive ductal carcinoma 19 | 2,951
Astrocytoma, Pilocytic 18 | 3,081
adrenocortical carcinoma 18 | 1,428
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
Kidney cancer 17 | 2,613
oligodendroglioma 16 | 2,850
Atopic dermatitis 14 | 952
colon cancer 14 | 1,478
lung adenocarcinoma 14 | 2,716
ductal carcinoma in situ 13 | 1,745
lung carcinoma 13 | 2,843
breast carcinoma 12 | 1,638
nasopharyngeal carcinoma 12 | 1,058
subependymal giant cell astrocytoma 12 | 2,287
Cancer 11 | 2,499
Endometriosis 11 | 540
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
astrocytic glioma 10 | 2,597
pituitary cancer 10 | 1,972
Pick disease 9 | 1,894
pancreatic cancer 9 | 2,398
Neurodegenerative disease 8 | 414
Schizophrenia 8 | 1,160
interstitial cystitis 8 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
ulcerative colitis 8 | 1,819
Epilepsy 7 | 792
Small head 7 | 374
group 4 medulloblastoma 7 | 1,855
Cognitive delay 6 | 608
Global developmental delay 6 | 608
Intellectual disability 6 | 1,016
Mental and motor retardation 6 | 608
Microcephaly 6 | 166
Seizures 6 | 596
diabetes mellitus 6 | 1,728
spina bifida 6 | 1,074
Autosomal recessive predisposition 5 | 1,442
Liver cancer 5 | 604
Neuropathy 5 | 261
Rheumatoid arthritis 5 | 1,191
acute myeloid leukemia 5 | 783
dermatomyositis 5 | 966
hereditary spastic paraplegia 5 | 318
Amyotrophic lateral sclerosis 4 | 451
Endometrial cancer 4 | 311
Hyperreflexia 4 | 209
Paraplegia 4 | 74
Parkinson's disease 4 | 392
Sloping forehead 4 | 46
astrocytoma 4 | 1,146
fibroadenoma 4 | 559
pediatric high grade glioma 4 | 1,064
progressive supranuclear palsy 4 | 676
tuberculosis 4 | 2,010
Anteverted nostril 3 | 191
Babinski Reflex 3 | 100
Bipolar Disorder 3 | 666
Cerebellar Hypoplasia 3 | 61
Cerebrovascular disease 3 | 238
Congenital fibrosis of the extraocular muscles 3 | 13
Down syndrome 3 | 499
Dull intelligence 3 | 645
Fetal Growth Retardation 3 | 189
Infant, Small for Gestational Age 3 | 176
Intrauterine retardation 3 | 176
Lissencephaly 3 | 69
Liver Cirrhosis, Experimental 3 | 769
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Poor school performance 3 | 645
Progressive disorder 3 | 142
Progressive muscular atrophy 3 | 7
Psychotic Disorders 3 | 151
Short stature 3 | 531
Spastic Quadriplegia 3 | 42
active Crohn's disease 3 | 922
chronic rhinosinusitis 3 | 512
cutaneous lupus erythematosus 3 | 1,057
posterior fossa group A ependymoma 3 | 468
primary Sjogren syndrome 3 | 735
primary pancreatic ductal adenocarcinoma 3 | 1,109
Brain Ischemia 2 | 110

Tissue

Endocrine System 70 | 18,159
Digestive Tract 68 | 17,369
Female tissues 68 | 17,400
Blood and immune system 67 | 16,909
Liver and Pancreas 67 | 16,750
Male tissues 67 | 17,142
Nervous System 67 | 16,725
Respiratory system 67 | 16,393
Skin and soft tissues 67 | 17,230
Urinary Tract 67 | 16,678
Cardiovascular System 64 | 15,192

Target Family

Non-IDG 63 | 12,091
Enzyme 6 | 4,145
Kinase 1 | 634

Compartment GO Term

Kinesin complex 70 | 70
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Syntabulin SYBU Tbio Non-IDG -0.98265 12.1 14
Kinesin-like protein KIF3A KIF3A Tbio Non-IDG -2.06068 113.6 153
Kinesin-like protein KIF22 KIF22 Tbio Non-IDG -1.69996 54.3 147
Kinesin-like protein KIF6 KIF6 Tbio Non-IDG -1.53414 38.4 157
Kinesin-like protein KIF3B KIF3B Tbio Non-IDG -1.37859 20.9 98
Fasciculation and elongation protein zeta-1 FEZ1 Tbio Non-IDG -1.36578 25.0 142
Dynactin subunit 2 DCTN2 Tbio Non-IDG -1.88460 67.4 257
C-Jun-amino-terminal kinase-interacting protein 1 MAPK8IP1 Tbio Enzyme -2.85543 697.4 180
Kinesin light chain 2 KLC2 Tbio Non-IDG -0.71842 5.05 153
C-Jun-amino-terminal kinase-interacting protein 3 MAPK8IP3 Tbio Enzyme -1.68844 56.5 128