Development Level

Tbio 28 | 11,651
Tdark 4 | 6,593
Tchem 1 | 1,388

IMPC Phenotype

preweaning lethality, incomple... 5 | 499
decreased circulating insulin ... 2 | 76
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal vibrissa morphology 1 | 25
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased circulating sodium l... 1 | 22
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
increased IgG2b level 1 | 1
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased mean corpuscular vol... 1 | 92
male infertility 1 | 123
prenatal lethality prior to he... 1 | 87
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 27 | 11,493
psoriasis 19 | 6,694
non-small cell lung cancer 15 | 2,890
Breast cancer 13 | 3,578
Palmoplantar keratosis 13 | 74
esophageal adenocarcinoma 13 | 737
Cancer 12 | 2,499
ovarian cancer 12 | 8,520
osteosarcoma 11 | 7,950
Kidney cancer 10 | 2,613
Epidermolytic hyperkeratosis 9 | 14
lung cancer 9 | 4,740
pancreatic cancer 9 | 2,398
spina bifida 9 | 1,074
Abnormal blistering of the skin 8 | 54
Blister of skin 8 | 54
Dystrophia unguium 8 | 53
Hyperhidrosis disorder 8 | 81
Increased sweating 8 | 81
Keratosis 8 | 37
Skin bulla 8 | 54
Sweating 8 | 81
breast carcinoma 8 | 1,638
ductal carcinoma in situ 8 | 1,745
Congenital ichthyosiform erythroderma 7 | 28
Squamous cell carcinoma 7 | 129
cystic fibrosis 7 | 1,696
interstitial cystitis 7 | 2,312
Atopic dermatitis 6 | 952
Autosomal recessive predisposition 6 | 1,442
Bullous pemphigoid 6 | 18
Carcinoma, Squamous Cell 6 | 110
Dermatitis 6 | 157
Epidermolysis bullosa 6 | 21
Epidermolysis bullosa simplex 6 | 9
Erythema 6 | 58
Flushing 6 | 60
Leukokeratosis 6 | 19
Leukoplakia, Oral 6 | 20
Monilethrix 6 | 18
Onychogryposis 6 | 13
Pachyonychia congenita 6 | 10
cutaneous lupus erythematosus 6 | 1,057
nasopharyngeal carcinoma 6 | 1,058
Breast Neoplasms 5 | 445
Dental caries 5 | 164
Hereditary mucosal leukokeratosis 5 | 7
Ichthyoses 5 | 41
Ichthyosis 5 | 56
Liver cancer 5 | 604
Mammary Neoplasms 5 | 425
Nail Diseases 5 | 24
Nail abnormality 5 | 22
Rotting teeth 5 | 73
Skin cancer 5 | 469
adult high grade glioma 5 | 3,801
periodontitis 5 | 293
Atrophic scar 4 | 18
Contact Dermatitis 4 | 81
Dermatitis, Contact 4 | 71
Eczema 4 | 45
Growth delay 4 | 114
Growth failure 4 | 114
Growth retardation 4 | 115
Hyperkeratosis, Epidermolytic 4 | 7
Ichthyosis vulgaris 4 | 11
Lichen planus 4 | 16
Melanoma 4 | 711
Nail dysplasia 4 | 52
Papilloma 4 | 44
Poor growth 4 | 114
Recurrent skin infections 4 | 21
Skin Neoplasms 4 | 69
Very poor growth 4 | 114
lung adenocarcinoma 4 | 2,716
malignant mesothelioma 4 | 3,232
medulloblastoma, large-cell 4 | 6,241
Abnormality of nail color 3 | 5
Abnormality of the fingernails 3 | 51
Alopecia 3 | 115
Ameloblastoma 3 | 24
Contracture 3 | 96
Contracture of joint 3 | 93
DOID:2627 3 | 94
Ecchymosis 3 | 66
Exfoliative dermatitis 3 | 24
Flexion contracture 3 | 93
Flexion contractures of joints 3 | 93
Hair shaft abnormalities 3 | 30
Increased tendency to bruise 3 | 66
Milium Cyst 3 | 16
Prenatal onset 3 | 139
Skin disease 3 | 66
Syringoma 3 | 11
Warts 3 | 10
gastric carcinoma 3 | 807
hair abnormalities (non-specific) 3 | 30
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
oligodendroglioma 3 | 2,850
ulcerative colitis 3 | 1,819

Tissue

Female tissues 29 | 17,400
Skin and soft tissues 29 | 17,230
Digestive Tract 28 | 17,369
Blood and immune system 27 | 16,909
Endocrine System 27 | 18,159
Male tissues 25 | 17,142
Nervous System 22 | 16,725
Liver and Pancreas 21 | 16,750
Urinary Tract 21 | 16,678
Respiratory system 19 | 16,393
Cardiovascular System 16 | 15,192

Target Family

Non-IDG 32 | 12,091
GPCR 1 | 408

Compartment GO Term

Keratin filament 33 | 33
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Filaggrin FLG Tbio Non-IDG -3.03594 1055.2 253
Desmoglein-3 DSG3 Tbio Non-IDG -2.57795 402.0 381
Desmoglein-1 DSG1 Tbio Non-IDG -2.72159 516.2 406
Trichohyalin TCHH Tbio Non-IDG -2.70168 475.4 20
Keratin, type I cytoskeletal 13 KRT13 Tbio Non-IDG -2.25522 171.2 403
Keratin, type II cytoskeletal 5 KRT5 Tbio Non-IDG -2.87489 691.1 885
Keratin, type I cytoskeletal 10 KRT10 Tbio Non-IDG -2.84299 654.9 785
Dystonin DST Tbio Non-IDG -2.73231 506.0 127
Keratin, type II cytoskeletal 71 KRT71 Tbio Non-IDG -0.88301 7.82 64
Loricrin LOR Tbio Non-IDG -2.58018 365.6 49