Development Level

Tbio 5 | 11,445

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal retina morphology 1 | 71
cataract 1 | 92
embryonic lethality prior to t... 1 | 278

Disease

ovarian cancer 3 | 8,520
Carcinoma 2 | 11,493
Friedreich ataxia 2 | 24
Sideroblastic anemia 2 | 20
Abnormal iron deposition in mitochondria 1 | 1
Acidosis, Lactic 1 | 97
Acquired immunodeficiency syndrome 1 | 197
Autosomal recessive predisposition 1 | 1,442
Breast cancer 1 | 3,578
Cardiomegaly 1 | 116
Cardiovascular system disease 1 | 246
Cerebrotendinous xanthomatosis 1 | 13
Congenital adrenal hyperplasia 1 | 73
Congenital adrenal insufficiency 1 | 7
Congenital bile acid synthesis defect 1 | 15
Creatine phosphokinase serum increased 1 | 110
Decreased activity of mitochondrial complex II 1 | 3
Decreased mitochondrial complex I activity 1 | 2
Decreased mitochondrial complex III activity 1 | 2
Diarrhea 1 | 253
Dyspnea 1 | 76
Elevated creatine kinase 1 | 110
Gastroenteritis 1 | 41
Hepatitis 1 | 67
Hepatitis E 1 | 11
Impaired exercise tolerance 1 | 42
Increased intramyocellular lipid droplets 1 | 13
Increased serum lactate 1 | 60
Lactic acidemia 1 | 95
Lactic acidosis 1 | 51
Learning disability 1 | 17
MYOPATHY WITH EXERCISE INTOLERANCE, SWEDISH TYPE 1 | 1
Mitochondrial Myopathies 1 | 21
Multiple myeloma 1 | 1,332
Muscle Cramp 1 | 55
Muscle Weakness 1 | 170
Myoglobinuria 1 | 15
Myopathy 1 | 185
Myopathy with lactic acidosis, hereditary 1 | 1
Ornithosis 1 | 9
Palpitations 1 | 18
Proliferative diabetic retinopathy 1 | 4
Prostatic Neoplasms 1 | 495
Respiratory complex I deficiency 1 | 2
Respiratory complex II deficiency 1 | 3
Respiratory complex III deficiency 1 | 2
Severe acute respiratory syndrome 1 | 27
Subacute bacterial endocarditis 1 | 3
Subsarcolemmal accumulations of abnormally shaped mitochondria 1 | 4
Usher syndrome type 1 1 | 10
Vascular disease 1 | 319
adrenocortical carcinoma 1 | 1,428
astrocytic glioma 1 | 2,597
infantile cerebellar-retinal degeneration 1 | 3
lung cancer 1 | 4,740
malignant mesothelioma 1 | 3,232
medulloblastoma, large-cell 1 | 6,241
non-small cell lung cancer 1 | 2,890
osteosarcoma 1 | 7,950
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
psoriasis 1 | 6,694
ulcerative colitis 1 | 1,819

Tissue

Endocrine System 5 | 18,159
Blood and immune system 4 | 16,909
Cardiovascular System 4 | 15,192
Digestive Tract 4 | 17,369
Female tissues 4 | 17,400
Liver and Pancreas 4 | 16,750
Male tissues 4 | 17,142
Nervous System 4 | 16,725
Respiratory system 4 | 16,393
Skin and soft tissues 4 | 17,230
Urinary Tract 4 | 16,678

Target Family

Non-IDG 5 | 12,091

Compartment GO Term

IscS-IscU complex 5 | 5
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 ASZ1 Tbio Non-IDG -2.81661 644.9 107
Iron-sulfur cluster co-chaperone protein HscB, mitochondrial HSCB Tbio Non-IDG -1.63830 47.3 42
Iron-sulfur cluster assembly enzyme ISCU, mitochondrial ISCU Tbio Non-IDG -2.25839 167.3 167
Adrenodoxin, mitochondrial FDX1 Tbio Non-IDG -2.81884 673.3 46
Glutaredoxin-3 GLRX3 Tbio Non-IDG -1.93135 90.3 243