Development Level

Tchem 9 | 1,598
Tbio 8 | 11,445

Collection

Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

embryonic lethality prior to t... 2 | 278
increased lean body mass 2 | 172
preweaning lethality, complete... 2 | 979
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal neural tube closure 1 | 46
decreased IgG1 level 1 | 8
decreased T cell number 1 | 15
decreased circulating HDL chol... 1 | 68
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
decreased lean body mass 1 | 135
decreased red blood cell distr... 1 | 41
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating glucose ... 1 | 24
increased circulating triglyce... 1 | 42
increased grip strength 1 | 41
increased mean corpuscular vol... 1 | 92
increased total body fat amoun... 1 | 134
vertebral fusion 1 | 23

Disease

Cancer 13 | 2,499
Carcinoma 13 | 11,493
osteosarcoma 10 | 7,950
ovarian cancer 9 | 8,520
psoriasis 9 | 6,694
Vascular disease 8 | 319
diabetes mellitus 8 | 1,728
lung cancer 7 | 4,740
glioblastoma 6 | 5,792
Alzheimer's disease 5 | 658
Bipolar Disorder 5 | 666
Obesity 5 | 678
Schizophrenia 5 | 1,160
lung adenocarcinoma 5 | 2,716
lung carcinoma 5 | 2,843
medulloblastoma, large-cell 5 | 6,241
Breast cancer 4 | 3,578
Kidney cancer 4 | 2,613
Multiple myeloma 4 | 1,332
Parkinson's disease 4 | 392
Toxic encephalopathy 4 | 141
atypical teratoid / rhabdoid tumor 4 | 5,112
ependymoma 4 | 4,679
hepatocellular carcinoma 4 | 547
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
pancreatic cancer 4 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
spina bifida 4 | 1,074
Asbestosis 3 | 20
Fatty Liver 3 | 70
Fatty liver disease 3 | 103
Liver Cirrhosis, Experimental 3 | 769
Rheumatoid arthritis 3 | 1,191
active Crohn's disease 3 | 922
acute myeloid leukemia 3 | 783
astrocytoma 3 | 1,146
cystic fibrosis 3 | 1,696
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
malignant mesothelioma 3 | 3,232
non-small cell lung cancer 3 | 2,890
pituitary cancer 3 | 1,972
tuberculosis 3 | 2,010
Bipolar I disorder 2 | 23
Chemical and Drug Induced Liver Injury 2 | 195
Depressive disorder 2 | 409
Diabetes Mellitus, Insulin-Dependent 2 | 48
Diabetes Mellitus, Type 1 2 | 43
Eye disease 2 | 62
Heart disease 2 | 306
Inflammatory bowel disease 2 | 151
Kidney disease 2 | 430
Leukoencephalopathy with vanishing white matter 2 | 20
Liver disease 2 | 237
Mental Depression 2 | 333
Multiple Sclerosis 2 | 540
Myocardial Infarction 2 | 151
Neurodegenerative disease 2 | 414
Pick disease 2 | 1,894
Prostatic Neoplasms 2 | 495
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
adult high grade glioma 2 | 3,801
aldosterone-producing adenoma 2 | 665
gastric cancer 2 | 459
group 4 medulloblastoma 2 | 1,855
invasive ductal carcinoma 2 | 2,951
juvenile dermatomyositis 2 | 1,187
non primary Sjogren syndrome sicca 2 | 891
pancreatic carcinoma 2 | 562
pediatric high grade glioma 2 | 1,064
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 1,819
Alzheimer Disease 1 | 83
Amyotrophic lateral sclerosis 1 | 451
Breast Neoplasms 1 | 445
Cardiomyopathies 1 | 110
Congenital nystagmus 1 | 26
Disease Models, Animal 1 | 155
Esophageal Squamous Cell Carcinoma 1 | 77
Gaucher disease type 1 1 | 180
Hyperalgesia 1 | 83
Hypoxia 1 | 33
Liver Failure, Acute 1 | 29
Low Vision 1 | 174
Mammary Neoplasms 1 | 425
Melanoma 1 | 711
Microphthalmia with limb anomalies 1 | 40
Necrosis 1 | 53
Nerve Degeneration 1 | 121
Osteoporosis 1 | 363
Parkinson Disease 1 | 64
Photodysphoria 1 | 121
Photophobia 1 | 121
Somatic mutation 1 | 61
Squamous cell carcinoma of esophagus 1 | 77
Visual Impairment 1 | 174
X-linked cerebral adrenoleukodystrophy 1 | 116
atypical teratoid/rhabdoid tumor 1 | 357

Tissue

Blood and immune system 16 | 16,909
Digestive Tract 16 | 17,369
Endocrine System 16 | 18,159
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Male tissues 16 | 17,142
Nervous System 16 | 16,725
Respiratory system 16 | 16,393
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678
Cardiovascular System 15 | 15,192

Target Family

Kinase 5 | 634
Enzyme 4 | 4,145
Non-IDG 4 | 12,091
Transcription Factor 4 | 1,400

Compartment GO Term

Ire1 complex 17 | 17
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
X-box-binding protein 1 XBP1 Tchem Transcription Factor -2.90444 780.2 514
Endoplasmin HSP90B1 Tchem Non-IDG -2.76074 629.2 850
Caspase-4 CASP4 Tchem Enzyme -2.19377 147.3 520
DNA damage-inducible transcript 3 protein DDIT3 Tchem Transcription Factor -2.94434 736.0 704
Tripartite motif-containing protein 3 TRIM3 Tbio Non-IDG -1.44939 27.8 167
Serine/threonine-protein kinase/endoribonuclease IRE2 ERN2 Tbio Kinase -1.29793 19.9 175
2-5A-dependent ribonuclease RNASEL Tchem Kinase -2.71673 525.8 127
Mitogen-activated protein kinase kinase kinase 5 MAP3K5 Tchem Kinase -2.66223 525.4 1185
78 kDa glucose-regulated protein HSPA5 Tchem Non-IDG -3.35010 2184.4 1074
Inactive caspase-12 CASP12 Tbio Enzyme -2.64252 415.1 429