Development Level

Tbio 24 | 11,445
Tclin 17 | 613
Tdark 9 | 6,588
Tchem 7 | 1,598

Collection

Ion Channel: IDG Consortium (T... 6 | 99
RFA-RM-18-021 6 | 328

IMPC Phenotype

preweaning lethality, complete... 6 | 979
decreased total body fat amoun... 4 | 207
decreased body weight 3 | 161
decreased bone mineral content 2 | 151
decreased circulating HDL chol... 2 | 68
decreased exploration in new e... 2 | 11
decreased grip strength 2 | 116
embryonic lethality prior to o... 2 | 239
increased circulating alkaline... 2 | 122
increased lean body mass 2 | 172
abnormal QT variability 1 | 10
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal epididymis morphology 1 | 42
abnormal lens morphology 1 | 81
cataract 1 | 92
decreased circulating LDL chol... 1 | 38
decreased circulating aspartat... 1 | 34
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased heart weight 1 | 27
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased bone mineral content 1 | 108
increased circulating chloride... 1 | 41
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased mean corpuscular vol... 1 | 92
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
preweaning lethality, incomple... 1 | 499
tremors 1 | 39

Disease

Carcinoma 51 | 11,493
atypical teratoid / rhabdoid tumor 36 | 5,112
Schizophrenia 35 | 1,160
glioblastoma 35 | 5,792
medulloblastoma, large-cell 35 | 6,241
ependymoma 31 | 4,679
adult high grade glioma 30 | 3,801
oligodendroglioma 24 | 2,850
osteosarcoma 24 | 7,950
psoriasis 24 | 6,694
Astrocytoma, Pilocytic 23 | 3,081
Bipolar Disorder 23 | 666
Epilepsy 23 | 792
Kidney cancer 23 | 2,613
primitive neuroectodermal tumor 23 | 3,035
group 3 medulloblastoma 22 | 4,104
astrocytic glioma 20 | 2,597
lung carcinoma 18 | 2,843
ovarian cancer 18 | 8,520
subependymal giant cell astrocytoma 17 | 2,287
lung cancer 16 | 4,740
Pick disease 15 | 1,894
Toxic encephalopathy 15 | 141
Intellectual disability 14 | 1,016
Parkinson's disease 13 | 392
Major Depressive Disorder 12 | 301
Melanoma 12 | 711
group 4 medulloblastoma 12 | 1,855
General anesthesia 11 | 53
Lennox-Gastaut syndrome 11 | 34
Local anesthesia 11 | 40
Simple partial seizure 11 | 26
Alcoholic Intoxication, Chronic 10 | 289
Autistic Disorder 10 | 364
Tonic-clonic epilepsy 10 | 47
Unipolar Depression 10 | 250
pituitary cancer 10 | 1,972
Alzheimer's disease 9 | 658
Depressive disorder 9 | 409
Dull intelligence 9 | 645
Epilepsy characterized by intractable complex partial seizures 9 | 28
Low intelligence 9 | 645
Mental Depression 9 | 333
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Migraine Prevention 9 | 23
Poor school performance 9 | 645
Skin cancer 9 | 469
Cognitive delay 8 | 608
Global developmental delay 8 | 608
Mental and motor retardation 8 | 608
Alcoholism 7 | 45
Amyotrophic lateral sclerosis 7 | 451
Arteriosclerotic Parkinsonism 7 | 8
Attention deficit hyperactivity disorder 7 | 278
Cocaine-Related Disorders 7 | 92
Extrapyramidal disease 7 | 8
Huntington's disease 7 | 76
Influenza A Prevention 7 | 7
Influenza due to Influenza A virus 7 | 7
Parkinsonism 7 | 18
Postencephalitic parkinsonism 7 | 12
astrocytoma 7 | 1,146
Alcohol dependence 6 | 107
Fragile X syndrome 6 | 34
Mood Disorders 6 | 184
Muscle hypotonia 6 | 571
Neurodegenerative disease 6 | 414
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
invasive ductal carcinoma 6 | 2,951
lung adenocarcinoma 6 | 2,716
Autosomal recessive predisposition 5 | 1,442
Brain Ischemia 5 | 110
Breast cancer 5 | 3,578
Cerebrovascular disease 5 | 238
Psychotic Disorders 5 | 151
Seizures 5 | 596
Status Epilepticus 5 | 98
Vascular disease 5 | 319
interstitial cystitis 5 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
malignant mesothelioma 5 | 3,232
non primary Sjogren syndrome sicca 5 | 891
non-small cell lung cancer 5 | 2,890
pediatric high grade glioma 5 | 1,064
Amnestic disorder 4 | 35
Autism Spectrum Disorders 4 | 75
Autism spectrum disorder 4 | 101
Dementia 4 | 175
Encephalitis 4 | 64
Liver cancer 4 | 604
Moderate to Severe Alzheimer's Type Dementia 4 | 5
Pain agnosia 4 | 104
Partial seizure 4 | 15
Rheumatoid arthritis 4 | 1,191
Substance Withdrawal Syndrome 4 | 55
adrenocortical carcinoma 4 | 1,428
cystic fibrosis 4 | 1,696
ductal carcinoma in situ 4 | 1,745

Tissue

Endocrine System 57 | 18,159
Nervous System 57 | 16,725
Digestive Tract 51 | 17,369
Blood and immune system 50 | 16,909
Female tissues 50 | 17,400
Male tissues 50 | 17,142
Skin and soft tissues 50 | 17,230
Urinary Tract 50 | 16,678
Respiratory system 47 | 16,393
Liver and Pancreas 46 | 16,750
Cardiovascular System 38 | 15,192

Target Family

Ion Channel 23 | 344
Non-IDG 23 | 12,091
Enzyme 5 | 4,145
Transporter 3 | 473
GPCR 2 | 408
Kinase 1 | 634

Compartment GO Term

Ionotropic glutamate receptor ... 57 | 57
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Metabotropic glutamate receptor 5 GRM5 Tchem GPCR -3.12353 1370.3 396
Ras/Rap GTPase-activating protein SynGAP SYNGAP1 Tbio Enzyme -1.91757 81.2 178
Glutamate receptor-interacting protein 1 GRIP1 Tbio Non-IDG -2.18570 152.7 157
Glutamate receptor ionotropic, delta-2 GRID2 Tbio Ion Channel -2.05105 116.1 74
GRIP1-associated protein 1 GRIPAP1 Tbio Non-IDG -0.78090 6.63 132
Vesicular glutamate transporter 2 SLC17A6 Tbio Transporter -2.57663 372.2 154
AP-5 complex subunit beta-1 AP5B1 Tdark Non-IDG -3.06187 1110.1 7
Neuropilin and tolloid-like protein 1 NETO1 Tbio Non-IDG -1.00021 11.6 74
Protein shisa-6 homolog SHISA6 Tdark Non-IDG -0.09374 1.84 62
Neuropilin and tolloid-like protein 2 NETO2 Tbio Non-IDG -1.66114 47.4 144