Development Level

Tclin 17 | 602
Tbio 16 | 10,625
Tchem 12 | 1,890
Tdark 9 | 7,003

Collection

Ion Channel: IDG Consortium (Targets) 6 | 102

IMPC Phenotype

decreased lean body mass 3 | 195
preweaning lethality, complete... 3 | 633
decreased body weight 2 | 174
decreased grip strength 2 | 123
decreased total body fat amoun... 2 | 186
embryonic lethality prior to o... 2 | 148
increased circulating alkaline... 2 | 119
abnormal behavior 1 | 226
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal craniofacial morpholo... 1 | 12
abnormal cranium morphology 1 | 32
abnormal epididymis morphology 1 | 31
abnormal lens morphology 1 | 73
abnormal skin morphology 1 | 23
cataract 1 | 26
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 77
decreased circulating alanine ... 1 | 53
decreased circulating chloride... 1 | 32
decreased circulating choleste... 1 | 85
decreased circulating sodium l... 1 | 18
decreased circulating triglyce... 1 | 83
decreased effector memory CD8-... 1 | 24
decreased exploration in new e... 1 | 9
decreased heart weight 1 | 44
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased neutrophil cell numb... 1 | 37
enlarged epididymis 1 | 27
enlarged heart 1 | 111
hyperactivity 1 | 108
hypoactivity 1 | 89
increased bone mineral content 1 | 92
increased circulating chloride... 1 | 43
increased circulating phosphat... 1 | 24
increased eosinophil cell numb... 1 | 9
increased erythrocyte cell num... 1 | 26
increased lean body mass 1 | 107
increased red blood cell distr... 1 | 21
increased rib number 1 | 41
increased startle reflex 1 | 38
preweaning lethality, incomple... 1 | 260
straub tail 1 | 26
thrombocytopenia 1 | 46
tremors 1 | 34

Disease

medulloblastoma, large-cell 33 | 6,234
glioblastoma 32 | 5,572
Schizophrenia 27 | 503
atypical teratoid / rhabdoid tumor 27 | 4,369
Epilepsy 23 | 346
oligodendroglioma 23 | 2,849
pilocytic astrocytoma 23 | 3,086
primitive neuroectodermal tumor 23 | 3,031
psoriasis 23 | 6,685
osteosarcoma 22 | 7,933
pediatric high grade glioma 22 | 2,712
ependymoma 20 | 2,514
astrocytic glioma 19 | 2,241
Carcinoma 17 | 2,147
lung carcinoma 17 | 2,844
ovarian cancer 17 | 8,491
Toxic encephalopathy 16 | 131
group 4 medulloblastoma 16 | 1,875
subependymal giant cell astrocytoma 16 | 2,287
Pick disease 15 | 1,893
Bipolar Disorder 12 | 266
Parkinson's disease 12 | 364
General anesthesia 11 | 53
Lennox-Gastaut syndrome 11 | 34
Local anesthesia 11 | 40
Simple partial seizure 11 | 26
adult high grade glioma 11 | 2,148
lung cancer 11 | 4,473
Alzheimer's disease 10 | 644
Intellectual disability 10 | 573
Tonic-clonic epilepsy 10 | 47
pituitary cancer 10 | 1,972
Epilepsy characterized by intractable complex partial seizures 9 | 28
Migraine Prevention 9 | 22
medulloblastoma 9 | 1,524
posterior fossa group A ependymoma 9 | 1,511
Autistic Disorder 8 | 320
astrocytoma 8 | 1,493
atypical teratoid/rhabdoid tumor 8 | 1,095
Alcohol dependence 7 | 107
Alcoholism 7 | 14
Amyotrophic Lateral Sclerosis 7 | 432
Arteriosclerotic Parkinsonism 7 | 8
Cocaine-Related Disorders 7 | 88
Extrapyramidal disease 7 | 8
Huntington's disease 7 | 72
Influenza A Prevention 7 | 7
Influenza due to Influenza A virus 7 | 7
Neurodegenerative disease 7 | 383
Parkinsonism 7 | 19
Postencephalitic parkinsonism 7 | 12
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,289
Brain Ischemia 6 | 87
Cerebrovascular disease 6 | 231
Major Depressive Disorder 6 | 106
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
sonic hedgehog group medulloblastoma 6 | 1,482
Attention deficit hyperactivity disorder 5 | 156
Fragile X syndrome 5 | 31
Status Epilepticus 5 | 85
group 3 medulloblastoma 5 | 2,254
interstitial cystitis 5 | 2,299
invasive ductal carcinoma 5 | 2,950
lung adenocarcinoma 5 | 2,714
Amnestic disorder 4 | 37
Cancer 4 | 2,346
Down syndrome 4 | 548
Encephalitis 4 | 54
Moderate to Severe Alzheimer's Type Dementia 4 | 5
Pain agnosia 4 | 99
Partial seizure 4 | 15
Rheumatoid Arthritis 4 | 1,170
Substance Withdrawal Syndrome 4 | 55
Tetanus 4 | 66
Vascular disease 4 | 281
cystic fibrosis 4 | 1,670
diabetes mellitus 4 | 1,663
malignant mesothelioma 4 | 3,163
non primary Sjogren syndrome sicca 4 | 840
pancreatic cancer 4 | 2,300
Cerebellar Ataxia 3 | 72
Child Development Disorders, Pervasive 3 | 55
Dementia 3 | 129
Glaucoma 3 | 135
High pressure neurological syndrome 3 | 9
Melanoma 3 | 261
Morphine dependence 3 | 19
Nerve Degeneration 3 | 73
Neuropathy 3 | 210
Opiate dependence 3 | 12
Psychosexual Disorders 3 | 6
Substance-Related Disorders 3 | 114
ductal carcinoma in situ 3 | 1,745
gastric carcinoma 3 | 832
non-small cell lung cancer 3 | 2,798
obsessive-compulsive disorder 3 | 34
posterior fossa group B ependymoma 3 | 1,530
substance-related disorder 3 | 104
acute myeloid leukemia 2 | 785

Tissue

Digestive Tract 54 | 18,472
Endocrine System 54 | 18,511
Female tissues 54 | 18,646
Liver and Pancreas 54 | 18,135
Nervous System 54 | 18,560
Cardiovascular System 53 | 17,957
Skin and soft tissues 53 | 18,114
Urinary Tract 53 | 18,443
Blood and immune system 52 | 17,994
Male tissues 51 | 17,968
Respiratory system 51 | 17,483

Target Family

Ion Channel 23 | 341
Non-IDG 21 | 11,969
Enzyme 4 | 4,146
Transporter 3 | 473
GPCR 2 | 408
Kinase 1 | 634

Compartment GO Term

Ionotropic glutamate receptor ... 54 | 54
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Glutamate receptor ionotropic, delta-2 GRID2 Tbio Ion Channel -2.02679 111.0 70
Glutamate receptor 2 GRIA2 Tclin Ion Channel -2.63267 422.3 407
Glutamate receptor 1 GRIA1 Tclin Ion Channel -3.15085 1376.5 691
Glutamate receptor 3 GRIA3 Tclin Ion Channel -1.95421 83.7 203
Voltage-dependent calcium channel gamma-5 subunit CACNG5 Tchem Ion Channel 0.09 1.00 57
PRKCA-binding protein PICK1 Tbio Non-IDG -2.11607 148.6 326
Germ cell-specific gene 1-like protein GSG1L Tdark Non-IDG -0.69780 4.41 57
Glutamate receptor ionotropic, kainate 2 GRIK2 Tclin Ion Channel -2.42011 265.6 219
Glutamate receptor ionotropic, kainate 3 GRIK3 Tclin Ion Channel -1.48916 28.2 125
Protein shisa-7 SHISA7 Tdark Non-IDG 0.30 0.50 50