Development Level

Tclin 122 | 613
Tbio 114 | 11,445
Tchem 68 | 1,598
Tdark 27 | 6,588

Collection

Ion Channel: IDG Consortium (T... 53 | 99

IMPC Phenotype

preweaning lethality, complete... 23 | 979
abnormal behavior 10 | 298
preweaning lethality, incomple... 8 | 499
abnormal embryo size 7 | 220
hyperactivity 7 | 148
decreased body weight 6 | 161
decreased total body fat amoun... 6 | 207
embryonic lethality prior to t... 6 | 278
increased lean body mass 6 | 172
increased startle reflex 6 | 112
impaired glucose tolerance 5 | 75
abnormal behavioral response t... 4 | 66
embryonic growth retardation 4 | 106
increased bone mineral content 4 | 108
increased circulating chloride... 4 | 41
increased mean corpuscular vol... 4 | 92
abnormal bone structure 3 | 187
abnormal epididymis morphology 3 | 42
abnormal gait 3 | 69
decreased circulating LDL chol... 3 | 38
decreased circulating alkaline... 3 | 46
decreased fasted circulating g... 3 | 65
decreased grip strength 3 | 116
decreased mean platelet volume 3 | 25
decreased neutrophil cell numb... 3 | 42
edema 3 | 59
increased circulating sodium l... 3 | 71
increased circulating triglyce... 3 | 42
increased fasted circulating g... 3 | 76
prolonged ST segment 3 | 36
abnormal bone mineralization 2 | 38
abnormal eye morphology 2 | 68
abnormal seminal vesicle morph... 2 | 114
decreased bone mineral content 2 | 151
decreased cardiac stroke volum... 2 | 6
decreased circulating HDL chol... 2 | 68
decreased circulating glycerol... 2 | 16
decreased circulating sodium l... 2 | 22
decreased circulating total pr... 2 | 49
decreased circulating triglyce... 2 | 79
decreased heart weight 2 | 27
decreased prepulse inhibition 2 | 82
decreased vertical activity 2 | 208
enlarged heart 2 | 210
increased mean platelet volume 2 | 45
increased monocyte cell number 2 | 63
increased total body fat amoun... 2 | 134
limb grasping 2 | 41
prenatal lethality 2 | 28
prenatal lethality prior to he... 2 | 87
prolonged QT interval 2 | 38
tremors 2 | 39
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal embryo turning 1 | 31
abnormal head morphology 1 | 10
abnormal joint morphology 1 | 23
abnormal locomotor activation 1 | 16
abnormal lung morphology 1 | 26
abnormal response to new envir... 1 | 10
abnormal sensory capabilities-... 1 | 8
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
abnormal vocalization 1 | 21
absent vibrissae 1 | 12
anophthalmia 1 | 33
brachydactyly 1 | 19
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased body length 1 | 101
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased heart rate variabili... 1 | 13
decreased hematocrit 1 | 46
decreased red blood cell distr... 1 | 41
embryonic lethality prior to o... 1 | 239
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
hemorrhage 1 | 23
hydrometra 1 | 53
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
increased anti-nuclear antigen... 1 | 19
increased body length 1 | 32
increased circulating alanine ... 1 | 13
increased circulating creatini... 1 | 38
increased circulating fructosa... 1 | 13
increased circulating magnesiu... 1 | 10
increased heart rate 1 | 23
increased vertical activity 1 | 24
long tibia 1 | 25
small superior vagus ganglion 1 | 74
small testis 1 | 58
syndactyly 1 | 23

Disease

Carcinoma 263 | 11,493
medulloblastoma, large-cell 153 | 6,241
glioblastoma 144 | 5,792
atypical teratoid / rhabdoid tumor 137 | 5,112
ependymoma 135 | 4,679
psoriasis 131 | 6,694
adult high grade glioma 129 | 3,801
osteosarcoma 115 | 7,950
Kidney cancer 106 | 2,613
ovarian cancer 105 | 8,520
Astrocytoma, Pilocytic 103 | 3,081
group 3 medulloblastoma 103 | 4,104
oligodendroglioma 103 | 2,850
primitive neuroectodermal tumor 100 | 3,035
Epilepsy 98 | 792
astrocytic glioma 85 | 2,597
lung cancer 85 | 4,740
lung carcinoma 84 | 2,843
Schizophrenia 77 | 1,160
Breast cancer 67 | 3,578
subependymal giant cell astrocytoma 66 | 2,287
Bipolar Disorder 65 | 666
Pick disease 63 | 1,894
malignant mesothelioma 62 | 3,232
intraductal papillary-mucinous adenoma (IPMA) 60 | 2,955
pituitary cancer 60 | 1,972
intraductal papillary-mucinous neoplasm (IPMN) 54 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 53 | 2,989
lung adenocarcinoma 52 | 2,716
Autosomal recessive predisposition 51 | 1,442
Intellectual disability 46 | 1,016
Seizures 45 | 596
cystic fibrosis 44 | 1,696
Autistic Disorder 41 | 364
pancreatic cancer 41 | 2,398
Alcoholic Intoxication, Chronic 39 | 289
Depressive disorder 39 | 409
General anesthesia 39 | 53
interstitial cystitis 39 | 2,312
invasive ductal carcinoma 39 | 2,951
non-small cell lung cancer 39 | 2,890
Hypertension 37 | 396
colon cancer 37 | 1,478
Heart disease 36 | 306
Mental Depression 36 | 333
Cancer 35 | 2,499
Melanoma 35 | 711
Muscle hypotonia 34 | 571
Tonic-clonic epilepsy 33 | 47
Skin cancer 32 | 469
ductal carcinoma in situ 32 | 1,745
Dull intelligence 31 | 645
Low intelligence 31 | 645
Mental Retardation 31 | 645
Mental deficiency 31 | 645
Poor school performance 31 | 645
Atrial Fibrillation 30 | 124
Cognitive delay 29 | 608
Global developmental delay 29 | 608
Local anesthesia 29 | 40
Mental and motor retardation 29 | 608
Multiple Sclerosis 29 | 540
Liver cancer 28 | 604
diabetes mellitus 28 | 1,728
Alcohol dependence 27 | 107
Alzheimer's disease 27 | 658
Major Depressive Disorder 27 | 301
Neuropathy 27 | 261
group 4 medulloblastoma 27 | 1,855
Mood Disorders 26 | 184
Parkinson's disease 25 | 392
Infantile onset 24 | 238
Status Epilepticus 24 | 98
ulcerative colitis 24 | 1,819
Eaton-Lambert syndrome 23 | 40
Hypertensive disease 23 | 292
breast carcinoma 23 | 1,638
non primary Sjogren syndrome sicca 23 | 891
Lennox-Gastaut syndrome 22 | 34
Neurodegenerative disease 22 | 414
adrenocortical carcinoma 22 | 1,428
tuberculosis 22 | 2,010
Cerebellar Ataxia 21 | 304
Endometrial cancer 21 | 311
Long QT syndrome 21 | 39
Migraine 21 | 83
Toxic encephalopathy 21 | 141
Kidney disease 20 | 430
Simple partial seizure 20 | 26
Brugada syndrome 19 | 29
Constipation 19 | 181
Diarrhea 19 | 253
Epilepsy characterized by intractable complex partial seizures 19 | 28
Hypokalemia 19 | 52
Obesity 19 | 678
Pain agnosia 19 | 104
Panic disorder 19 | 61
Unipolar Depression 19 | 250
Failure to gain weight 18 | 365
Vascular disease 18 | 319

Tissue

Endocrine System 325 | 18,159
Nervous System 313 | 16,725
Digestive Tract 305 | 17,369
Female tissues 303 | 17,400
Skin and soft tissues 299 | 17,230
Male tissues 295 | 17,142
Blood and immune system 285 | 16,909
Liver and Pancreas 279 | 16,750
Urinary Tract 279 | 16,678
Respiratory system 263 | 16,393
Cardiovascular System 225 | 15,192

Target Family

Ion Channel 232 | 344
Non-IDG 64 | 12,091
Enzyme 18 | 4,145
GPCR 10 | 408
Transporter 5 | 473
Kinase 2 | 634

Compartment GO Term

Ion channel complex 331 | 331
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transient receptor potential cation channel subfamily V member 2 TRPV2 Tchem Ion Channel -2.28525 197.9 203
Calcium-activated potassium channel subunit beta-2 KCNMB2 Tbio Ion Channel 1.28 0.09 191
Leucine-rich repeat-containing protein 26 LRRC26 Tbio Ion Channel -1.02699 11.3 81
Leucine-rich glioma-inactivated protein 1 LGI1 Tbio Non-IDG -2.52790 342.7 207
Sodium channel protein type 10 subunit alpha SCN10A Tclin Ion Channel -3.17690 1469.3 126
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 HCN2 Tclin Ion Channel -1.16715 13.3 162
Potassium voltage-gated channel subfamily E member 3 KCNE3 Tbio Ion Channel -1.63683 41.4 75
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 ATP2A2 Tbio Transporter -2.87498 737.3 295
Calbindin CALB1 Tbio Non-IDG -3.31956 2149.9 287
CD2-associated protein CD2AP Tbio Non-IDG -3.44533 2735.9 82