Development Level

Tbio 927 | 11,445
Tchem 377 | 1,598
Tclin 285 | 613
Tdark 160 | 6,588

Collection

RFA-RM-18-021 95 | 328
GPCR: IDG Consortium (Targets) 47 | 126
Ion Channel: IDG Consortium (T... 47 | 99
GPCR: IDG Consortium (Complete... 16 | 25
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 70 | 979
preweaning lethality, incomple... 52 | 499
abnormal behavior 38 | 298
decreased vertical activity 27 | 208
enlarged heart 26 | 210
decreased total body fat amoun... 22 | 207
embryonic lethality prior to t... 22 | 278
hyperactivity 20 | 148
abnormal bone structure 19 | 187
abnormal embryo size 19 | 220
increased lean body mass 18 | 172
abnormal heart morphology 17 | 162
embryonic lethality prior to o... 17 | 239
decreased body weight 16 | 161
abnormal seminal vesicle morph... 15 | 114
increased total body fat amoun... 14 | 134
impaired glucose tolerance 13 | 75
increased circulating alkaline... 13 | 122
increased mean corpuscular vol... 13 | 92
increased startle reflex 13 | 112
small superior vagus ganglion 13 | 74
decreased bone mineral content 12 | 151
decreased grip strength 12 | 116
decreased lymphocyte cell numb... 12 | 83
decreased circulating insulin ... 11 | 76
decreased prepulse inhibition 11 | 82
hypoactivity 11 | 132
increased bone mineral content 11 | 108
increased circulating sodium l... 11 | 71
abnormal epididymis morphology 10 | 42
abnormal gait 10 | 69
improved glucose tolerance 10 | 79
limb grasping 10 | 41
tremors 10 | 39
abnormal eye morphology 9 | 68
decreased erythrocyte cell num... 9 | 62
decreased fasted circulating g... 9 | 65
increased circulating choleste... 9 | 66
increased leukocyte cell numbe... 9 | 47
increased mean corpuscular hem... 9 | 96
abnormal kidney morphology 8 | 65
abnormal retina morphology 8 | 71
cataract 8 | 92
decreased bone mineral density 8 | 126
decreased circulating HDL chol... 8 | 68
decreased circulating alkaline... 8 | 46
decreased circulating choleste... 8 | 93
decreased lean body mass 8 | 135
decreased mean corpuscular vol... 8 | 79
embryonic growth retardation 8 | 106
increased circulating HDL chol... 8 | 80
increased monocyte cell number 8 | 63
prolonged ST segment 8 | 36
abnormal lens morphology 7 | 81
abnormal sleep behavior 7 | 70
cardiovascular system phenotyp... 7 | 36
decreased body length 7 | 101
decreased circulating creatini... 7 | 39
decreased circulating glucose ... 7 | 126
decreased circulating triglyce... 7 | 79
decreased eosinophil cell numb... 7 | 24
enlarged epididymis 7 | 31
enlarged spleen 7 | 41
hydrometra 7 | 53
increased circulating chloride... 7 | 41
increased circulating triglyce... 7 | 42
increased neutrophil cell numb... 7 | 46
prolonged QT interval 7 | 38
short tibia 7 | 97
abnormal behavioral response t... 6 | 66
abnormal skin morphology 6 | 50
decreased circulating LDL chol... 6 | 38
decreased circulating calcium ... 6 | 36
decreased leukocyte cell numbe... 6 | 73
edema 6 | 59
increased circulating creatini... 6 | 38
increased erythrocyte cell num... 6 | 39
increased fasted circulating g... 6 | 76
male infertility 6 | 123
pale yolk sac 6 | 25
pallor 6 | 34
small testis 6 | 58
thrombocytopenia 6 | 56
abnormal bone mineralization 5 | 38
abnormal testis morphology 5 | 43
decreased blood urea nitrogen ... 5 | 51
decreased circulating amylase ... 5 | 28
decreased circulating serum al... 5 | 82
decreased heart weight 5 | 27
decreased mean corpuscular hem... 5 | 50
enlarged uterus 5 | 11
increased circulating amylase ... 5 | 25
increased circulating iron lev... 5 | 30
increased grip strength 5 | 41
increased heart weight 5 | 62
increased hematocrit 5 | 46
increased lymphocyte cell numb... 5 | 32
increased mean platelet volume 5 | 45
mammalian phenotype 5 | 17
polycystic kidney 5 | 15

Disease

Carcinoma 1,286 | 11,493
psoriasis 787 | 6,694
osteosarcoma 725 | 7,950
ovarian cancer 710 | 8,520
glioblastoma 645 | 5,792
medulloblastoma, large-cell 610 | 6,241
lung cancer 576 | 4,740
atypical teratoid / rhabdoid tumor 530 | 5,112
Cancer 528 | 2,499
ependymoma 504 | 4,679
lung carcinoma 482 | 2,843
adult high grade glioma 450 | 3,801
Astrocytoma, Pilocytic 423 | 3,081
non-small cell lung cancer 401 | 2,890
malignant mesothelioma 392 | 3,232
Breast cancer 383 | 3,578
Kidney cancer 383 | 2,613
interstitial cystitis 380 | 2,312
lung adenocarcinoma 373 | 2,716
invasive ductal carcinoma 372 | 2,951
group 3 medulloblastoma 367 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 360 | 3,291
intraductal papillary-mucinous adenoma (IPMA) 354 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 348 | 2,989
pancreatic cancer 336 | 2,398
oligodendroglioma 318 | 2,850
diabetes mellitus 304 | 1,728
primitive neuroectodermal tumor 294 | 3,035
tuberculosis 294 | 2,010
Schizophrenia 283 | 1,160
ulcerative colitis 282 | 1,819
astrocytic glioma 276 | 2,597
subependymal giant cell astrocytoma 271 | 2,287
pituitary cancer 261 | 1,972
cystic fibrosis 252 | 1,696
Autosomal recessive predisposition 233 | 1,442
ductal carcinoma in situ 233 | 1,745
cutaneous lupus erythematosus 212 | 1,057
Rheumatoid arthritis 206 | 1,191
colon cancer 204 | 1,478
pancreatic ductal adenocarcinoma liver metastasis 197 | 1,962
breast carcinoma 196 | 1,638
group 4 medulloblastoma 175 | 1,855
Pick disease 169 | 1,894
Kidney disease 167 | 430
Bipolar Disorder 163 | 666
Multiple Sclerosis 163 | 540
Epilepsy 158 | 792
adrenocortical carcinoma 156 | 1,428
Liver Cirrhosis, Experimental 150 | 769
Arthritis 148 | 290
Hypertension 148 | 396
Hypersensitivity reaction type II disease 147 | 253
Melanoma 147 | 711
Obesity 146 | 678
primary pancreatic ductal adenocarcinoma 142 | 1,109
Depressive disorder 125 | 409
Alzheimer's disease 124 | 658
Asthma 123 | 385
astrocytoma 123 | 1,146
dermatomyositis 123 | 966
active Crohn's disease 121 | 922
Anemia 118 | 365
gastric carcinoma 117 | 807
Intellectual disability 114 | 1,016
nasopharyngeal carcinoma 113 | 1,058
pediatric high grade glioma 112 | 1,064
Skin cancer 109 | 469
primary Sjogren syndrome 107 | 735
Liver disease 106 | 237
active ulcerative colitis 105 | 764
mucosa-associated lymphoid tissue lymphoma 105 | 484
Mental Depression 104 | 333
esophageal adenocarcinoma 104 | 737
Atopic dermatitis 103 | 952
Seizures 103 | 596
Alcoholic Intoxication, Chronic 101 | 289
Atherosclerosis 101 | 291
juvenile dermatomyositis 101 | 1,187
Liver cancer 97 | 604
Coronary artery disease 96 | 268
spina bifida 96 | 1,074
Autistic Disorder 94 | 364
Heart disease 94 | 306
Hypertensive disease 94 | 292
Prostatic Neoplasms 92 | 495
Acquired immunodeficiency syndrome 91 | 197
Duchenne muscular dystrophy 91 | 601
Cerebrovascular disease 89 | 238
Down syndrome 89 | 499
Vascular disease 89 | 319
acute quadriplegic myopathy 89 | 1,158
Major Depressive Disorder 87 | 301
Breast Neoplasms 86 | 445
Mammary Neoplasms 85 | 425
Dermatitis 84 | 157
Endometriosis 84 | 540
aldosterone-producing adenoma 84 | 665
Low intelligence 83 | 645
Mental Retardation 83 | 645

Tissue

Endocrine System 1,623 | 18,159
Digestive Tract 1,570 | 17,369
Female tissues 1,557 | 17,400
Nervous System 1,540 | 16,725
Skin and soft tissues 1,540 | 17,230
Male tissues 1,534 | 17,142
Blood and immune system 1,514 | 16,909
Liver and Pancreas 1,514 | 16,750
Urinary Tract 1,513 | 16,678
Respiratory system 1,451 | 16,393
Cardiovascular System 1,305 | 15,192

Target Family

Non-IDG 781 | 12,091
GPCR 259 | 408
Transporter 227 | 473
Ion Channel 217 | 344
Enzyme 168 | 4,145
Kinase 78 | 634
Transcription Factor 10 | 1,400
oGPCR 9 | 421

Compartment GO Term

Intrinsic component of plasma ... 1,749 | 1,749
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Low affinity immunoglobulin gamma Fc region receptor II-c FCGR2C Tbio Non-IDG -2.61667 619.4 0
Carcinoembryonic antigen-related cell adhesion molecule 8 CEACAM8 Tbio Non-IDG -2.27709 182.9 314
Potassium voltage-gated channel subfamily A member 2 KCNA2 Tclin Ion Channel -2.55550 343.3 205
Post-GPI attachment to proteins factor 6 TMEM8A Tdark Non-IDG -0.56820 3.55 16
HLA class I histocompatibility antigen, B-35 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0
Tubulin beta-4A chain TUBB4A Tclin Non-IDG -2.98371 896.1 90
Protocadherin gamma-A9 PCDHGA9 Tdark Non-IDG 0.51 0.72 31
Metabotropic glutamate receptor 5 GRM5 Tchem GPCR -3.12353 1370.3 396
Protocadherin beta-14 PCDHB14 Tdark Non-IDG 0.78 0.14 90
Protocadherin beta-12 PCDHB12 Tdark Non-IDG 0.00000 88