Development Level

Tbio 17 | 11,445
Tdark 3 | 6,588
Tchem 2 | 1,598

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal adrenal gland morphol... 1 | 1
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal thymus morphology 1 | 7
abnormal vibrissa morphology 1 | 25
absent startle reflex 1 | 24
aorta dilation 1 | 3
cataract 1 | 92
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 46
decreased circulating iron lev... 1 | 32
decreased circulating magnesiu... 1 | 13
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased mean platelet volume 1 | 25
decreased vertical activity 1 | 208
enlarged epididymis 1 | 31
enlarged heart 1 | 210
hyperactivity 1 | 148
hypoactivity 1 | 132
increased circulating bilirubi... 1 | 16
increased circulating glycerol... 1 | 9
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased total body fat amoun... 1 | 134
prolonged QT interval 1 | 38
shortened QT interval 1 | 4
small adrenal glands 1 | 16
small superior vagus ganglion 1 | 74
small thymus 1 | 16

Disease

ovarian cancer 12 | 8,520
medulloblastoma, large-cell 9 | 6,241
osteosarcoma 8 | 7,950
atypical teratoid / rhabdoid tumor 7 | 5,112
glioblastoma 7 | 5,792
lung cancer 7 | 4,740
Carcinoma 6 | 11,493
psoriasis 6 | 6,694
Breast cancer 5 | 3,578
Multiple myeloma 4 | 1,332
Neurodegenerative disease 4 | 414
adult high grade glioma 4 | 3,801
dermatomyositis 4 | 966
diabetes mellitus 4 | 1,728
group 4 medulloblastoma 4 | 1,855
Astrocytoma, Pilocytic 3 | 3,081
Autosomal recessive predisposition 3 | 1,442
Neuropathy 3 | 261
Optic Atrophy 3 | 242
ependymoma 3 | 4,679
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
Absent reflex 2 | 92
Absent tendon reflex 2 | 92
Acquired scoliosis 2 | 281
Alzheimer's disease 2 | 658
Amyotrophic lateral sclerosis 2 | 451
Axonal degeneration/regeneration 2 | 7
Cancer 2 | 2,499
Cardiomegaly 2 | 116
Ceroid lipofuscinosis, neuronal 1, infantile 2 | 10
Charcot-Marie-Tooth disease 2 | 62
Congenital pes cavus 2 | 88
Contracture 2 | 96
Contracture of joint 2 | 93
Curvature of spine 2 | 282
Decreased motor NCV 2 | 22
Decreased number of large and small myelinated fibers 2 | 20
Decreased tendon reflex 2 | 122
Decreased to absent deep tendon reflexes 2 | 42
Distal amyotrophy 2 | 51
Distal limb muscle weakness due to peripheral neuropathy 2 | 62
Distal muscle weakness 2 | 62
Distal sensory impairment 2 | 52
Feeding difficulties in infancy 2 | 175
Flexion contracture 2 | 93
Flexion contractures of joints 2 | 93
Foot dorsiflexor weakness 2 | 27
Foot-drop 2 | 27
Gait, Drop Foot 2 | 24
Hammer Toe 2 | 23
Hepatomegaly 2 | 285
Hoarse voice due to vocal cord paresis 2 | 3
Infantile onset 2 | 238
Major Depressive Disorder 2 | 301
Muscle hypotonia 2 | 571
Muscle weakness of limb 2 | 21
Nerve Degeneration 2 | 121
Neurogenic Muscular Atrophy 2 | 139
Neurogenic muscle atrophy, especially in the lower limbs 2 | 139
Obesity 2 | 678
Onion bulb formation 2 | 19
Parkinson's disease 2 | 392
Partial Paralysis (Paresis) Vocal Cords 2 | 3
Pick disease 2 | 1,894
Polycystic ovary syndrome 2 | 360
Polyneuropathy 2 | 64
Proximal muscle weakness 2 | 47
Proximal neurogenic muscle weakness 2 | 47
Reflex, Deep Tendon, Absent 2 | 92
Rheumatoid arthritis 2 | 1,191
Skeletal muscle atrophy 2 | 139
Unipolar Depression 2 | 250
Vocal cord paresis in severe cases 2 | 3
Weakness of vocal cord 2 | 3
acute quadriplegic myopathy 2 | 1,158
astrocytic glioma 2 | 2,597
colon cancer 2 | 1,478
esophageal adenocarcinoma 2 | 737
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
juvenile dermatomyositis 2 | 1,187
malignant mesothelioma 2 | 3,232
medulloblastoma 2 | 720
muscle degeneration 2 | 139
non-small cell lung cancer 2 | 2,890
pituitary cancer 2 | 1,972
primary pancreatic ductal adenocarcinoma 2 | 1,109
primitive neuroectodermal tumor 2 | 3,035
ulcerative colitis 2 | 1,819
Abnormality of the endocrine system 1 | 9
Atrophy of testis 1 | 14
CNS hypomyelination 1 | 17
Charcot-Marie-Tooth disease axonal type 2K 1 | 2
Charcot-Marie-Tooth disease, Type 2K 1 | 2
Endocrine System Diseases 1 | 11
Hypomyelination 1 | 17
Kidney Failure, Chronic 1 | 46
Rapidly progressive 1 | 27
Rapidly progressive disorder 1 | 27

Tissue

Blood and immune system 22 | 16,909
Cardiovascular System 22 | 15,192
Digestive Tract 22 | 17,369
Endocrine System 22 | 18,159
Female tissues 22 | 17,400
Liver and Pancreas 22 | 16,750
Male tissues 22 | 17,142
Nervous System 22 | 16,725
Respiratory system 22 | 16,393
Skin and soft tissues 22 | 17,230
Urinary Tract 22 | 16,678

Target Family

Non-IDG 14 | 12,091
Enzyme 4 | 4,145
Kinase 2 | 634
Transporter 2 | 473

Compartment GO Term

Intrinsic component of mitocho... 22 | 22
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myotonin-protein kinase DMPK Tchem Kinase -2.70945 496.6 196
ATP-binding cassette sub-family B member 6, mitochondrial ABCB6 Tbio Transporter -2.65393 430.3 137
Mitofusin-2 MFN2 Tbio Non-IDG -2.68784 484.6 447
FUN14 domain-containing protein 1 FUNDC1 Tbio Non-IDG -1.21206 16.0 151
Mitochondrial ubiquitin ligase activator of NFKB 1 MUL1 Tbio Enzyme -2.41710 245.8 150
Ganglioside-induced differentiation-associated protein 1 GDAP1 Tbio Non-IDG -1.99050 105.9 77
Mitochondrial import receptor subunit TOM40 homolog TOMM40 Tbio Non-IDG -2.21973 158.9 94
Bcl-2 homologous antagonist/killer BAK1 Tbio Non-IDG -2.29199 175.9 554
Carnitine O-palmitoyltransferase 1, liver isoform CPT1A Tchem Enzyme -2.38489 225.0 306
FUN14 domain-containing protein 2 FUNDC2 Tdark Non-IDG -0.67611 3.86 78