Development Level

Tbio 14 | 11,178
Tchem 5 | 1,885
Tdark 3 | 6,569

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal adrenal gland morphol... 1 | 1
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal thymus morphology 1 | 7
abnormal vibrissa morphology 1 | 25
absent startle reflex 1 | 24
aorta dilation 1 | 3
cataract 1 | 92
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 46
decreased circulating iron lev... 1 | 32
decreased circulating magnesiu... 1 | 13
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased mean platelet volume 1 | 25
decreased vertical activity 1 | 208
enlarged epididymis 1 | 31
enlarged heart 1 | 210
hyperactivity 1 | 148
hypoactivity 1 | 132
increased circulating bilirubi... 1 | 16
increased circulating glycerol... 1 | 9
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased total body fat amoun... 1 | 134
prolonged QT interval 1 | 38
shortened QT interval 1 | 4
small adrenal glands 1 | 16
small superior vagus ganglion 1 | 74
small thymus 1 | 16

Disease

ovarian cancer 12 | 8,297
medulloblastoma, large-cell 9 | 6,086
osteosarcoma 8 | 7,766
atypical teratoid / rhabdoid tumor 7 | 4,971
glioblastoma 7 | 5,635
lung cancer 7 | 4,607
Carcinoma 6 | 11,192
psoriasis 6 | 6,514
Breast cancer 5 | 3,469
Multiple myeloma 4 | 1,296
Neurodegenerative disease 4 | 402
adult high grade glioma 4 | 3,701
dermatomyositis 4 | 941
diabetes mellitus 4 | 1,683
group 4 medulloblastoma 4 | 1,806
Astrocytoma, Pilocytic 3 | 3,006
Autosomal recessive predisposition 3 | 1,407
Neuropathy 3 | 254
Optic Atrophy 3 | 239
ependymoma 3 | 4,559
group 3 medulloblastoma 3 | 4,002
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,872
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,204
Absent reflex 2 | 90
Absent tendon reflex 2 | 90
Acquired scoliosis 2 | 274
Alzheimer's disease 2 | 640
Amyotrophic lateral sclerosis 2 | 437
Axonal degeneration/regeneration 2 | 7
Cancer 2 | 2,388
Cardiomegaly 2 | 114
Ceroid lipofuscinosis, neuronal 1, infantile 2 | 10
Charcot-Marie-Tooth disease 2 | 59
Congenital pes cavus 2 | 86
Contracture 2 | 95
Contracture of joint 2 | 92
Curvature of spine 2 | 275
Decreased motor NCV 2 | 22
Decreased number of large and small myelinated fibers 2 | 20
Decreased tendon reflex 2 | 121
Decreased to absent deep tendon reflexes 2 | 42
Distal amyotrophy 2 | 49
Distal limb muscle weakness due to peripheral neuropathy 2 | 60
Distal muscle weakness 2 | 60
Distal sensory impairment 2 | 50
Feeding difficulties in infancy 2 | 174
Flexion contracture 2 | 92
Flexion contractures of joints 2 | 92
Foot dorsiflexor weakness 2 | 27
Foot-drop 2 | 27
Gait, Drop Foot 2 | 24
Hammer Toe 2 | 23
Hepatomegaly 2 | 280
Hoarse voice due to vocal cord paresis 2 | 2
Infantile onset 2 | 236
Major Depressive Disorder 2 | 293
Muscle hypotonia 2 | 562
Muscle weakness of limb 2 | 21
Nerve Degeneration 2 | 118
Neurogenic Muscular Atrophy 2 | 136
Neurogenic muscle atrophy, especially in the lower limbs 2 | 136
Obesity 2 | 655
Onion bulb formation 2 | 18
Parkinson's disease 2 | 378
Partial Paralysis (Paresis) Vocal Cords 2 | 2
Pick disease 2 | 1,856
Polycystic ovary syndrome 2 | 348
Polyneuropathy 2 | 63
Proximal muscle weakness 2 | 47
Proximal neurogenic muscle weakness 2 | 47
Reflex, Deep Tendon, Absent 2 | 90
Rheumatoid arthritis 2 | 1,156
Skeletal muscle atrophy 2 | 136
Unipolar Depression 2 | 244
Vocal cord paresis in severe cases 2 | 2
Weakness of vocal cord 2 | 2
acute quadriplegic myopathy 2 | 1,133
astrocytic glioma 2 | 2,530
colon cancer 2 | 1,428
esophageal adenocarcinoma 2 | 696
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,902
juvenile dermatomyositis 2 | 1,147
malignant mesothelioma 2 | 3,135
medulloblastoma 2 | 702
muscle degeneration 2 | 136
non-small cell lung cancer 2 | 2,799
pituitary cancer 2 | 1,915
primary pancreatic ductal adenocarcinoma 2 | 1,071
primitive neuroectodermal tumor 2 | 2,957
ulcerative colitis 2 | 1,765
Abnormality of the endocrine system 1 | 9
Atrophy of testis 1 | 14
CNS hypomyelination 1 | 17
Claw hand 1 | 25
Endocrine System Diseases 1 | 11
Hypomyelination 1 | 17
Peripheral hypomyelination 1 | 7
Photosensitivity of skin 1 | 51
Rapidly progressive disorder 1 | 27
Spinocerebellar ataxia type 12 1 | 5

Tissue

Blood and immune system 22 | 16,909
Cardiovascular System 22 | 15,192
Digestive Tract 22 | 17,369
Endocrine System 22 | 18,159
Female tissues 22 | 17,400
Liver and Pancreas 22 | 16,750
Male tissues 22 | 17,142
Nervous System 22 | 16,725
Respiratory system 22 | 16,393
Skin and soft tissues 22 | 17,230
Urinary Tract 22 | 16,678

Target Family

Non-IDG 14 | 12,091
Enzyme 4 | 4,145
Kinase 2 | 634
Transporter 2 | 473

Compartment GO Term

Intrinsic component of mitocho... 22 | 22
cellular_component 17,863 | 17,863
Cell 15,779 | 15,779
Cell part 15,778 | 15,778
Intracellular 13,764 | 13,764
Intracellular part 13,630 | 13,630
Organelle 11,921 | 11,921
Intracellular organelle 11,712 | 11,712
membrane-bounded organelle 10,823 | 10,823
Cytoplasm 10,720 | 10,720
Intracellular membrane-bounded... 10,057 | 10,057
Cytoplasmic part 9,029 | 9,029
Organelle part 8,755 | 8,755
Intracellular organelle part 8,566 | 8,566
Membrane 8,335 | 8,335
Nucleus 7,336 | 7,336
Cytosol 6,551 | 6,551
Membrane part 6,403 | 6,403
Plasma membrane 5,682 | 5,682
Macromolecular complex 5,345 | 5,345
Intrinsic component of membran... 5,320 | 5,320
Cell periphery 5,248 | 5,248
Integral component of membrane 5,197 | 5,197
Nucleoplasm 4,931 | 4,931
Intracellular organelle lumen 4,923 | 4,923
Organelle lumen 4,923 | 4,923
membrane-enclosed lumen 4,923 | 4,923
Nuclear part 4,169 | 4,169
Endomembrane system 4,108 | 4,108
Intracellular non-membrane-bou... 3,917 | 3,917
non-membrane-bounded organelle 3,917 | 3,917
Nuclear lumen 3,851 | 3,851
Protein complex 3,565 | 3,565
Organelle membrane 2,798 | 2,798
Extracellular region 2,600 | 2,600
Plasma membrane part 2,531 | 2,531
Vesicle 2,280 | 2,280
Cytoplasmic vesicle 2,158 | 2,158
Intracellular vesicle 2,157 | 2,157
Cytoskeleton 2,084 | 2,084
Bounding membrane of organelle 1,924 | 1,924
Endoplasmic reticulum 1,922 | 1,922
Golgi apparatus 1,884 | 1,884
Intrinsic component of plasma ... 1,701 | 1,701
Integral component of plasma m... 1,647 | 1,647
Cytoskeletal part 1,613 | 1,613
Catalytic complex 1,592 | 1,592
Vesicles 1,566 | 1,566
Mitochondrion 1,557 | 1,557
Extracellular region part 1,533 | 1,533
Cell projection 1,524 | 1,524
Whole membrane 1,521 | 1,521
Cytoplasmic vesicle part 1,468 | 1,468
Endoplasmic reticulum part 1,315 | 1,315
GO:0031975 1,139 | 1,139
Organelle envelope 1,131 | 1,131
Microtubule cytoskeleton 1,127 | 1,127
Nucleoplasm part 1,100 | 1,100
Nuclear outer membrane-endopla... 1,094 | 1,094
Endoplasmic reticulum membrane 1,076 | 1,076
Extracellular space 1,059 | 1,059
Mitochondrial part 1,027 | 1,027
Chromosome 1,020 | 1,020
Mitochondria 985 | 985
Neuron part 958 | 958
Supramolecular polymer 950 | 950
Cell junction 949 | 949
Supramolecular complex 949 | 949
Supramolecular fiber 942 | 942
Secretory vesicle 930 | 930
Golgi apparatus part 923 | 923
Nucleoli 923 | 923
Nucleolus 916 | 916
Endosome 915 | 915
Chromosomal part 872 | 872
GO:0098796 868 | 868
Ribonucleoprotein complex 845 | 845
Cell projection part 838 | 838
Transferase complex 837 | 837
Intracellular ribonucleoprotei... 830 | 830
Plasma membrane region 826 | 826
Secretory granule 810 | 810
Cell surface 805 | 805
Vesicle membrane 786 | 786
Cytoplasmic vesicle membrane 780 | 780
Polymeric cytoskeletal fiber 753 | 753
Mitochondrial envelope 739 | 739
Golgi membrane 715 | 715
Microtubule organizing center 712 | 712
Nuclear body 708 | 708
Vacuole 708 | 708
Neuron projection 701 | 701
Mitochondrial membrane 689 | 689
Centrosome 685 | 685
Extracellular matrix 670 | 670
Receptor complex 670 | 670
Synapse 656 | 656
Lysosome 600 | 600
Lytic vacuole 600 | 600
Endosomal part 554 | 554
Chromatin 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Bcl-2 homologous antagonist/killer BAK1 Tchem Non-IDG -2.29199 175.9 554
FUN14 domain-containing protein 1 FUNDC1 Tbio Non-IDG -1.21206 16.0 151
Myotonin-protein kinase DMPK Tchem Kinase -2.70945 496.6 196
Mitochondrial ubiquitin ligase activator of NFKB 1 MUL1 Tbio Enzyme -2.41710 245.8 150
Mitochondrial import receptor subunit TOM40 homolog TOMM40 Tbio Non-IDG -2.21973 158.9 94
Ganglioside-induced differentiation-associated protein 1 GDAP1 Tbio Non-IDG -1.99050 105.9 77
Mitofusin-2 MFN2 Tbio Non-IDG -2.68784 484.6 447
ATP-binding cassette sub-family B member 6, mitochondrial ABCB6 Tchem Transporter -2.65393 430.3 137
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 BNIP3 Tbio Non-IDG -2.51675 340.9 331
Mitochondrial fission 1 protein FIS1 Tbio Non-IDG -2.19572 143.4 224