Development Level

Tbio 175 | 10,625
Tchem 19 | 1,890
Tdark 18 | 7,003
Tclin 1 | 602

IMPC Term

preweaning lethality, complete... 10 | 633
decreased lean body mass 4 | 195
abnormal bone structure 3 | 131
decreased bone mineral content 3 | 157
decreased circulating alanine ... 3 | 53
decreased circulating insulin ... 3 | 75
decreased total body fat amoun... 3 | 186
embryonic lethality prior to t... 3 | 187
increased total body fat amoun... 3 | 57
abnormal bone mineralization 2 | 55
abnormal gait 2 | 51
abnormal retina morphology 2 | 100
abnormal retinal pigmentation 2 | 61
decreased T cell number 2 | 31
decreased mean corpuscular vol... 2 | 50
decreased startle reflex 2 | 48
embryonic lethality prior to o... 2 | 148
enlarged heart 2 | 111
hyperactivity 2 | 108
increased circulating alkaline... 2 | 119
increased grip strength 2 | 83
increased lean body mass 2 | 107
increased mean corpuscular vol... 2 | 91
increased or absent threshold ... 2 | 128
limb grasping 2 | 35
preweaning lethality, incomple... 2 | 260
thrombocytopenia 2 | 46
abnormal behavior 1 | 226
abnormal coat/hair pigmentatio... 1 | 54
abnormal eye morphology 1 | 38
abnormal eye size 1 | 11
abnormal hair growth 1 | 8
abnormal retinal blood vessel ... 1 | 18
abnormal seminal vesicle morph... 1 | 47
abnormal vocalization 1 | 21
absent vibrissae 1 | 14
convulsive seizures 1 | 11
decreased B cell number 1 | 30
decreased CD8-positive, alpha-... 1 | 26
decreased IgG1 level 1 | 4
decreased NK T cell number 1 | 28
decreased NK cell number 1 | 16
decreased blood urea nitrogen ... 1 | 31
decreased body weight 1 | 174
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 41
decreased circulating aspartat... 1 | 27
decreased circulating choleste... 1 | 85
decreased circulating fructosa... 1 | 31
decreased circulating glucose ... 1 | 121
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased circulating triglyce... 1 | 83
decreased granulocyte number 1 | 8
decreased heart weight 1 | 44
decreased lactate dehydrogenas... 1 | 14
decreased mean corpuscular hem... 1 | 34
enlarged spleen 1 | 26
hydroencephaly 1 | 6
hypoactivity 1 | 89
increased KLRG1-positive NK ce... 1 | 9
increased T cell number 1 | 15
increased bone mineral content 1 | 92
increased circulating HDL chol... 1 | 63
increased circulating choleste... 1 | 53
increased circulating magnesiu... 1 | 10
increased effector memory CD8-... 1 | 14
increased mean platelet volume 1 | 19
male infertility 1 | 62
microphthalmia 1 | 15
mydriasis 1 | 9
persistence of hyaloid vascula... 1 | 22
prenatal lethality prior to he... 1 | 64
small adrenal glands 1 | 15
thin ventricular wall 1 | 5
tremors 1 | 34
vertebral fusion 1 | 23

Disease

psoriasis 95 | 6,685
ovarian cancer 90 | 8,492
Cancer 88 | 2,346
diabetes mellitus 81 | 1,663
Ankylosing spondylitis 72 | 138
osteosarcoma 69 | 7,933
Hypersensitivity reaction type II disease 62 | 235
Juvenile rheumatoid arthritis 60 | 105
Acquired immunodeficiency syndrome 56 | 164
Arthritis 56 | 248
Behcet's disease 56 | 74
Uveitis 56 | 103
glioblastoma 56 | 5,572
Rheumatoid Arthritis 53 | 1,171
dermatomyositis 53 | 967
Psoriatic arthritis 52 | 85
Stevens-Johnson syndrome 51 | 91
Human immunodeficiency virus infectious disease 49 | 129
medulloblastoma, large-cell 49 | 6,234
lung cancer 42 | 4,473
pilocytic astrocytoma 36 | 3,086
Behcet's syndrome 35 | 50
Congenital adrenal hyperplasia 35 | 74
Dermatitis 35 | 141
Nephritis 35 | 63
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
Synovitis 35 | 72
Takayasu's arteritis 35 | 54
atypical teratoid / rhabdoid tumor 35 | 4,369
drug-induced hepatitis 35 | 44
Breast cancer 33 | 3,099
Multiple Sclerosis 33 | 498
lung carcinoma 30 | 2,844
astrocytoma 29 | 1,493
pancreatic ductal adenocarcinoma liver metastasis 28 | 1,795
Multiple myeloma 27 | 1,328
invasive ductal carcinoma 27 | 2,950
intraductal papillary-mucinous neoplasm (IPMN) 26 | 3,289
juvenile dermatomyositis 26 | 1,189
Liver disease 25 | 219
Leprosy 24 | 77
intraductal papillary-mucinous carcinoma (IPMC) 24 | 2,988
non-small cell lung cancer 24 | 2,798
Hepatitis B 23 | 103
Kidney disease 23 | 397
interstitial cystitis 23 | 2,299
oligodendroglioma 23 | 2,849
Hemochromatosis 22 | 55
ependymoma 22 | 2,514
Anemia 21 | 252
Birdshot chorioretinopathy 21 | 23
Primary immunodeficiency disease 21 | 52
Skin disease 21 | 65
subependymal giant cell astrocytoma 21 | 2,287
active Crohn's disease 20 | 918
pediatric high grade glioma 20 | 2,712
tuberculosis 20 | 1,563
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,956
malignant mesothelioma 18 | 3,163
pancreatic cancer 18 | 2,300
pituitary cancer 18 | 1,972
group 4 medulloblastoma 17 | 1,875
lung adenocarcinoma 17 | 2,714
posterior fossa group A ependymoma 17 | 1,511
primitive neuroectodermal tumor 17 | 3,031
breast carcinoma 16 | 1,614
Neurodegenerative disease 15 | 383
Pick disease 15 | 1,893
adult high grade glioma 15 | 2,148
esophageal adenocarcinoma 15 | 737
pre-eclampsia 15 | 67
Human immunodeficiency virus type 1, susceptibility to 14 | 26
Psoriasis susceptibility 1 14 | 14
astrocytic glioma 14 | 2,241
primary Sjogren syndrome 14 | 789
ulcerative colitis 14 | 2,087
group 3 medulloblastoma 13 | 2,254
Duchenne muscular dystrophy 12 | 602
acute quadriplegic myopathy 12 | 1,157
Atopic dermatitis 11 | 944
cystic fibrosis 11 | 1,670
adrenocortical carcinoma 10 | 1,427
ductal carcinoma in situ 10 | 1,745
Down syndrome 9 | 548
Waldenstrons macroglobulinemia 9 | 765
active ulcerative colitis 9 | 477
aldosterone-producing adenoma 9 | 664
cutaneous lupus erythematosus 9 | 1,056
primary pancreatic ductal adenocarcinoma 9 | 1,271
progressive supranuclear palsy 9 | 674
Intellectual disability 8 | 573
Obesity 8 | 616
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 499
hereditary spastic paraplegia 8 | 313
medulloblastoma 8 | 1,524
non primary Sjogren syndrome sicca 8 | 840
acute myeloid leukemia 7 | 785
colon cancer 7 | 1,475
spina bifida 7 | 1,064

Tissue

Cardiovascular System 150 | 17,958
Digestive Tract 149 | 18,473
Endocrine System 149 | 18,512
Female tissues 149 | 18,647
Liver and Pancreas 149 | 18,136
Nervous System 149 | 18,561
Urinary Tract 149 | 18,444
Blood and immune system 148 | 17,995
Male tissues 148 | 17,969
Respiratory system 148 | 17,484
Skin and soft tissues 142 | 18,115

Target Family

Non-IDG 149 | 11,969
Enzyme 45 | 4,146
Transporter 10 | 473
Transcription Factor 6 | 1,400
Kinase 2 | 634
Ion Channel 1 | 341

Compartment GO Term

Intrinsic component of endopla... 213 | 213
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,612 | 13,612
Intracellular part 13,475 | 13,475
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,353 | 10,353
Membrane 8,871 | 8,871
Organelle part 8,169 | 8,169
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,831 | 7,831
Nucleus 7,577 | 7,577
Membrane part 6,469 | 6,469
Cytosol 6,034 | 6,034
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,930 | 4,930
Extracellular region 4,607 | 4,607
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,874 | 3,874
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,592 | 2,592
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,530 | 1,530
Cell projection 1,425 | 1,425
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,092 | 1,092
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,084 | 1,084
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 988 | 988
Nucleoli 950 | 950
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 815 | 815
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 656 | 656
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HLA class I histocompatibility antigen, alpha chain G HLA-G Tbio Non-IDG -3.07995 1275.9 729
Extended synaptotagmin-1 ESYT1 Tbio Non-IDG -1.25329 16.9 149
HLA class II histocompatibility antigen, DP beta 1 chain HLA-DPB1 Tbio Non-IDG -2.67719 572.7 274
Bile acyl-CoA synthetase SLC27A5 Tbio Transporter -2.25055 166.6 135
HLA class I histocompatibility antigen, A-3 alpha chain HLA-A Tbio Non-IDG -2.40709 4042.7 585
Alkaline ceramidase 3 ACER3 Tbio Enzyme -2.04148 105.9 85
ER membrane protein complex subunit 9 EMC9 Tdark Non-IDG 0.85 0.10 10
Sterol regulatory element-binding protein 2 SREBF2 Tchem Transcription Factor -2.56765 331.3 195
Aspartyl/asparaginyl beta-hydroxylase ASPH Tbio Enzyme -2.67468 471.0 197
Calreticulin CALR Tbio Non-IDG -3.16449 1423.9 650