Development Level

Tbio 40 | 11,651
Tdark 12 | 6,593
Tchem 1 | 1,388

Collection

GPCR: IDG Consortium (Targets) 1 | 126
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 13 | 979
preweaning lethality, incomple... 4 | 499
abnormal behavior 3 | 298
decreased lean body mass 3 | 135
increased total body fat amoun... 3 | 134
decreased body weight 2 | 161
embryonic lethality prior to t... 2 | 278
hypoactivity 2 | 132
impaired glucose tolerance 2 | 75
increased circulating chloride... 2 | 41
increased startle reflex 2 | 112
prenatal lethality prior to he... 2 | 87
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal nail morphology 1 | 8
abnormal pelvic girdle bone mo... 1 | 12
abnormal response to tactile s... 1 | 17
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal startle reflex 1 | 15
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased circulating free fat... 1 | 31
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased lactate dehydrogenas... 1 | 16
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
hyperactivity 1 | 148
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased circulating free fat... 1 | 20
increased circulating glycerol... 1 | 9
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased prepulse inhibition 1 | 32
limb grasping 1 | 41
long tibia 1 | 25
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28

Disease

Carcinoma 41 | 11,493
ependymoma 30 | 4,679
Polydactyly 29 | 107
osteosarcoma 25 | 7,950
ovarian cancer 24 | 8,520
Ciliopathy 22 | 71
Nephronophthisis 18 | 80
Asphyxiating thoracic dystrophy 17 | 44
Bardet-Biedl syndrome 16 | 51
glioblastoma 16 | 5,792
chronic rhinosinusitis 15 | 512
medulloblastoma, large-cell 15 | 6,241
psoriasis 15 | 6,694
atypical teratoid / rhabdoid tumor 14 | 5,112
group 3 medulloblastoma 13 | 4,104
Autosomal recessive predisposition 12 | 1,442
Intellectual disability 12 | 1,016
Short stature 12 | 531
Ulnar polydactyly of fingers 12 | 47
malignant mesothelioma 12 | 3,232
Dull intelligence 11 | 645
Joubert syndrome 11 | 66
Low intelligence 11 | 645
Mental Retardation 11 | 645
Mental deficiency 11 | 645
Obesity 11 | 678
Poor school performance 11 | 645
Retinitis Pigmentosa 11 | 226
Sensenbrenner syndrome 11 | 17
lung cancer 11 | 4,740
Brachydactyly 10 | 156
Nystagmus 10 | 317
Congenital hypoplasia of penis 9 | 176
Ellis-Van Creveld syndrome 9 | 19
Jeune thoracic dystrophy 9 | 10
Kidney cancer 9 | 2,613
Short Rib-Polydactyly Syndrome 9 | 13
Electroretinogram abnormal 8 | 95
Hypertensive disease 8 | 292
Hypogonadism 8 | 173
Increase in blood pressure 8 | 119
Multicystic Dysplastic Kidney 8 | 52
primitive neuroectodermal tumor 8 | 3,035
Cognitive delay 7 | 608
Congenital hypoplasia of ovary 7 | 30
Cryptorchidism 7 | 296
Gastrointestinal Stromal Tumors 7 | 48
Global developmental delay 7 | 608
Hypoplastic ovary 7 | 30
Meckel syndrome 7 | 46
Mental and motor retardation 7 | 608
Senior-Loken syndrome 7 | 22
adult high grade glioma 7 | 3,801
diabetes mellitus 7 | 1,728
Breast cancer 6 | 3,578
Hypoplastic feet 6 | 66
Narrow thorax 6 | 53
Optic Atrophy 6 | 242
Polydactyly of toes 6 | 12
Retinal Degeneration 6 | 106
Small genitalia 6 | 13
Strabismus 6 | 270
astrocytic glioma 6 | 2,597
cystic fibrosis and chronic rhinosinusitis 6 | 214
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
Abnormality of pelvic girdle bone morphology 5 | 37
Abnormality of the metaphyses 5 | 48
Bardet-Biedl syndrome 1 5 | 22
Cataract 5 | 297
Cerebellar Ataxia 5 | 304
Cranioectodermal Dysplasia 5 | 5
Cystic kidney disease 5 | 26
Hydrocephalus 5 | 152
Hypodontia 5 | 81
Lens Opacities 5 | 231
Micromelia 5 | 58
Orofaciodigital syndrome 5 | 21
Pick disease 5 | 1,894
Respiratory Insufficiency 5 | 132
Short rib-polydactyly syndrome, Verma-Naumoff type 5 | 5
Short thorax 5 | 21
Short-rib thoracic dysplasia 3 with or without polydactyly 5 | 9
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
invasive ductal carcinoma 5 | 2,951
lung carcinoma 5 | 2,843
medulloblastoma 5 | 720
nasopharyngeal carcinoma 5 | 1,058
oligodendroglioma 5 | 2,850
pancreatic cancer 5 | 2,398
Craniosynostosis 4 | 74
Hypoplastic mandible condyle 4 | 275
Intrauterine retardation 4 | 176
Mandibular hypoplasia 4 | 275
Orbital separation diminished 4 | 23
Syndactyly 4 | 88
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pediatric high grade glioma 4 | 1,064
progressive supranuclear palsy 4 | 676
subependymal giant cell astrocytoma 4 | 2,287

Tissue

Endocrine System 53 | 18,159
Male tissues 53 | 17,142
Digestive Tract 52 | 17,369
Liver and Pancreas 52 | 16,750
Nervous System 52 | 16,725
Skin and soft tissues 52 | 17,230
Female tissues 51 | 17,400
Respiratory system 51 | 16,393
Urinary Tract 51 | 16,678
Blood and immune system 50 | 16,909
Cardiovascular System 48 | 15,192

Target Family

Non-IDG 43 | 12,091
Enzyme 6 | 4,145
Transcription Factor 2 | 1,400
GPCR 1 | 408
Ion Channel 1 | 344

Compartment GO Term

Intraciliary transport particl... 53 | 53
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Meckel syndrome type 1 protein MKS1 Tbio Non-IDG -1.31837 20.5 59
Ras-related protein Rab-23 RAB23 Tbio Enzyme -1.63391 45.2 211
Tetratricopeptide repeat protein 30A TTC30A Tdark Non-IDG 0.60 0.00000 57
Kinesin-like protein KIF3A KIF3A Tbio Non-IDG -2.06068 113.6 153
Intraflagellar transport protein 27 homolog IFT27 Tbio Enzyme -1.24496 16.5 91
Bardet-Biedl syndrome 7 protein BBS7 Tbio Non-IDG -1.05503 10.4 159
Intraflagellar transport protein 81 homolog IFT81 Tbio Non-IDG -2.04582 108.8 104
Kinesin-like protein KIF3B KIF3B Tbio Non-IDG -1.37859 20.9 98
Intraflagellar transport protein 57 homolog IFT57 Tbio Non-IDG -1.31031 23.8 197
Intraflagellar transport protein 122 homolog IFT122 Tbio Non-IDG -1.52417 33.7 53