Development Level

Tbio 92 | 11,651
Tdark 50 | 6,593
Tchem 12 | 1,388

Collection

Kinase: IDG Consortium (Target... 2 | 125
RFA-RM-18-021 2 | 328
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 9 | 979
preweaning lethality, incomple... 5 | 499
increased lean body mass 4 | 172
embryonic lethality prior to t... 3 | 278
abnormal skin morphology 2 | 50
abnormal spleen morphology 2 | 55
decreased bone mineral content 2 | 151
decreased circulating glucose ... 2 | 126
decreased circulating insulin ... 2 | 76
decreased lean body mass 2 | 135
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
prenatal lethality prior to he... 2 | 87
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal hair growth 1 | 10
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal testis morphology 1 | 43
abnormal vocalization 1 | 21
absent testes 1 | 6
decreased bone mineral density 1 | 126
decreased circulating bilirubi... 1 | 19
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
decreased startle reflex 1 | 75
decreased urine magnesium leve... 1 | 3
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
enlarged spleen 1 | 41
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased blood uric acid leve... 1 | 5
increased circulating LDL chol... 1 | 13
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating glucose ... 1 | 24
increased circulating phosphat... 1 | 26
increased circulating sodium l... 1 | 71
increased exploration in new e... 1 | 8
increased granulocyte number 1 | 1
increased grip strength 1 | 41
increased heart rate 1 | 23
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased total body fat amoun... 1 | 134
prolonged PQ interval 1 | 5
prolonged ST segment 1 | 36
small testis 1 | 58
thrombocytosis 1 | 27

Disease

Carcinoma 110 | 11,493
ovarian cancer 86 | 8,520
osteosarcoma 72 | 7,950
psoriasis 63 | 6,694
glioblastoma 60 | 5,792
atypical teratoid / rhabdoid tumor 56 | 5,112
medulloblastoma, large-cell 56 | 6,241
lung cancer 48 | 4,740
ependymoma 47 | 4,679
Breast cancer 39 | 3,578
adult high grade glioma 36 | 3,801
group 3 medulloblastoma 36 | 4,104
malignant mesothelioma 36 | 3,232
non-small cell lung cancer 33 | 2,890
primitive neuroectodermal tumor 32 | 3,035
Astrocytoma, Pilocytic 29 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 29 | 3,291
intraductal papillary-mucinous adenoma (IPMA) 28 | 2,955
invasive ductal carcinoma 28 | 2,951
lung carcinoma 27 | 2,843
oligodendroglioma 26 | 2,850
pancreatic cancer 26 | 2,398
lung adenocarcinoma 24 | 2,716
interstitial cystitis 23 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,989
subependymal giant cell astrocytoma 22 | 2,287
Kidney cancer 21 | 2,613
astrocytic glioma 21 | 2,597
Cancer 20 | 2,499
breast carcinoma 20 | 1,638
colon cancer 19 | 1,478
cystic fibrosis 19 | 1,696
pituitary cancer 19 | 1,972
spina bifida 19 | 1,074
Pick disease 18 | 1,894
ductal carcinoma in situ 18 | 1,745
group 4 medulloblastoma 18 | 1,855
tuberculosis 17 | 2,010
adrenocortical carcinoma 13 | 1,428
astrocytoma 13 | 1,146
esophageal adenocarcinoma 13 | 737
ulcerative colitis 13 | 1,819
primary pancreatic ductal adenocarcinoma 12 | 1,109
Atopic dermatitis 11 | 952
Liver cancer 11 | 604
active Crohn's disease 11 | 922
dermatomyositis 11 | 966
juvenile dermatomyositis 11 | 1,187
Autosomal recessive predisposition 10 | 1,442
acute quadriplegic myopathy 10 | 1,158
cutaneous lupus erythematosus 10 | 1,057
diabetes mellitus 10 | 1,728
medulloblastoma 10 | 720
nasopharyngeal carcinoma 10 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
Multiple myeloma 9 | 1,332
Rheumatoid arthritis 9 | 1,191
fibroadenoma 9 | 559
Palmoplantar keratosis 8 | 74
Parkinson's disease 8 | 392
Dental caries 7 | 164
Duchenne muscular dystrophy 7 | 601
atypical teratoid/rhabdoid tumor 7 | 357
chronic rhinosinusitis 7 | 512
gastric carcinoma 7 | 807
non primary Sjogren syndrome sicca 7 | 891
pancreatic carcinoma 7 | 562
pediatric high grade glioma 7 | 1,064
Amyotrophic lateral sclerosis 6 | 451
Down syndrome 6 | 499
Liver Cirrhosis, Experimental 6 | 769
Myopathy 6 | 185
Short stature 6 | 531
Waldenstrons macroglobulinemia 6 | 765
active ulcerative colitis 6 | 764
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
cystic fibrosis and chronic rhinosinusitis 6 | 214
posterior fossa group B ependymoma 6 | 416
primary Sjogren syndrome 6 | 735
Abnormal blistering of the skin 5 | 54
Blister of skin 5 | 54
Breast Neoplasms 5 | 445
Cell Transformation, Neoplastic 5 | 97
Dystrophia unguium 5 | 53
Epilepsy 5 | 792
Failure to gain weight 5 | 365
Leukokeratosis 5 | 19
Leukoplakia, Oral 5 | 20
Mammary Neoplasms 5 | 425
Melanoma 5 | 711
Neoplastic Cell Transformation 5 | 89
Onychogryposis 5 | 13
Pachyonychia congenita 5 | 10
Pediatric failure to thrive 5 | 365
Rotting teeth 5 | 73
Skin bulla 5 | 54
progressive supranuclear palsy 5 | 676
sonic hedgehog group medulloblastoma 5 | 467
tuberculosis and treatment for 6 months 5 | 409
Schizophrenia 4 | 1,160

Tissue

Digestive Tract 153 | 17,369
Female tissues 152 | 17,400
Skin and soft tissues 152 | 17,230
Endocrine System 150 | 18,159
Male tissues 150 | 17,142
Blood and immune system 149 | 16,909
Urinary Tract 149 | 16,678
Respiratory system 148 | 16,393
Nervous System 147 | 16,725
Liver and Pancreas 146 | 16,750
Cardiovascular System 138 | 15,192

Target Family

Non-IDG 94 | 12,091
Enzyme 33 | 4,145
Transcription Factor 13 | 1,400
Kinase 6 | 634
Transporter 5 | 473
Epigenetic 2 | 242
Ion Channel 1 | 344

Compartment GO Term

Intermediate filaments 154 | 154
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger CCHC domain-containing protein 9 ZCCHC9 Tdark Non-IDG 0.48 0.71 31
Protein zyg-11 homolog B ZYG11B Tdark Non-IDG -0.49136 2.50 52
Monocarboxylate transporter 3 SLC16A8 Tbio Transporter -1.52718 33.5 105
Alsin ALS2 Tbio Non-IDG -2.20492 161.9 180
GRAM domain-containing protein 1B GRAMD1B Tdark Non-IDG -0.37654 2.90 39
Kinesin-like protein KIF3A KIF3A Tbio Non-IDG -2.06068 113.6 153
Dystrobrevin alpha DTNA Tbio Non-IDG -2.25692 181.5 151
Glial fibrillary acidic protein GFAP Tbio Non-IDG -3.50578 2828.7 1992
Putative ATP-dependent RNA helicase DHX57 DHX57 Tdark Enzyme 0.23 0.58 43
Dolichyldiphosphatase 1 DOLPP1 Tdark Enzyme 0.30 0.50 60