Development Level

Tbio 210 | 11,445
Tdark 52 | 6,588
Tchem 46 | 1,598
Tclin 22 | 613

Collection

Kinase: IDG Consortium (Target... 2 | 125
RFA-RM-18-021 2 | 328

IMPC Phenotype

preweaning lethality, complete... 15 | 979
preweaning lethality, incomple... 14 | 499
abnormal seminal vesicle morph... 4 | 114
decreased circulating alkaline... 4 | 46
decreased circulating insulin ... 4 | 76
embryonic lethality prior to t... 4 | 278
enlarged heart 4 | 210
increased startle reflex 4 | 112
abnormal behavior 3 | 298
decreased total body fat amoun... 3 | 207
decreased vertical activity 3 | 208
increased blood urea nitrogen ... 3 | 48
increased body length 3 | 32
increased circulating sodium l... 3 | 71
increased mean corpuscular vol... 3 | 92
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
abnormal heart morphology 2 | 162
abnormal lens morphology 2 | 81
abnormal retina morphology 2 | 71
abnormal vocalization 2 | 21
cataract 2 | 92
decreased body weight 2 | 161
decreased circulating HDL chol... 2 | 68
decreased circulating calcium ... 2 | 36
decreased circulating choleste... 2 | 93
decreased circulating glucose ... 2 | 126
decreased circulating serum al... 2 | 82
decreased coping response 2 | 8
decreased grip strength 2 | 116
decreased hematocrit 2 | 46
decreased leukocyte cell numbe... 2 | 73
decreased lymphocyte cell numb... 2 | 83
hyperactivity 2 | 148
hypoactivity 2 | 132
improved glucose tolerance 2 | 79
increased circulating HDL chol... 2 | 80
increased circulating choleste... 2 | 66
increased circulating creatini... 2 | 38
increased heart rate 2 | 23
increased total body fat amoun... 2 | 134
limb grasping 2 | 41
short tibia 2 | 97
abnormal coat- hair morphology 1 | 19
abnormal coat-hair pigmentatio... 1 | 64
abnormal eye morphology 1 | 68
abnormal gait 1 | 69
abnormal head morphology 1 | 10
abnormal placenta size 1 | 20
abnormal retinal inner nuclear... 1 | 8
abnormal sleep behavior 1 | 70
abnormal spine curvature 1 | 9
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal vertebrae morphology 1 | 18
absent vibrissae 1 | 12
cardiovascular system phenotyp... 1 | 36
convulsive seizures 1 | 13
decreased T cell number 1 | 15
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating creatini... 1 | 39
decreased circulating free fat... 1 | 31
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased fluid intake 1 | 3
decreased heart rate variabili... 1 | 13
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
embryonic lethality prior to o... 1 | 239
enlarged uterus 1 | 11
impaired glucose tolerance 1 | 75
increased blood uric acid leve... 1 | 5
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating free fat... 1 | 20
increased circulating iron lev... 1 | 30
increased circulating magnesiu... 1 | 10
increased circulating phosphat... 1 | 26
increased circulating serum al... 1 | 22
increased exploration in new e... 1 | 8
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
premature death 1 | 5
prenatal lethality prior to he... 1 | 87
shortened RR interval 1 | 17
small spleen 1 | 19
small superior vagus ganglion 1 | 74
tremors 1 | 39

Disease

Carcinoma 226 | 11,493
Cancer 167 | 2,499
psoriasis 163 | 6,694
ovarian cancer 155 | 8,520
glioblastoma 126 | 5,792
lung cancer 118 | 4,740
osteosarcoma 117 | 7,950
Breast cancer 110 | 3,578
ependymoma 110 | 4,679
atypical teratoid / rhabdoid tumor 109 | 5,112
medulloblastoma, large-cell 103 | 6,241
malignant mesothelioma 88 | 3,232
Astrocytoma, Pilocytic 86 | 3,081
Schizophrenia 81 | 1,160
adult high grade glioma 80 | 3,801
lung carcinoma 77 | 2,843
group 3 medulloblastoma 76 | 4,104
lung adenocarcinoma 75 | 2,716
intraductal papillary-mucinous neoplasm (IPMN) 74 | 3,291
non-small cell lung cancer 74 | 2,890
diabetes mellitus 72 | 1,728
invasive ductal carcinoma 71 | 2,951
oligodendroglioma 71 | 2,850
intraductal papillary-mucinous adenoma (IPMA) 70 | 2,955
pancreatic cancer 69 | 2,398
interstitial cystitis 66 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 65 | 2,989
cystic fibrosis 64 | 1,696
Kidney cancer 62 | 2,613
Alzheimer's disease 59 | 658
pituitary cancer 58 | 1,972
primitive neuroectodermal tumor 58 | 3,035
breast carcinoma 57 | 1,638
astrocytic glioma 56 | 2,597
Autosomal recessive predisposition 55 | 1,442
subependymal giant cell astrocytoma 53 | 2,287
ulcerative colitis 53 | 1,819
ductal carcinoma in situ 51 | 1,745
Kidney disease 48 | 430
colon cancer 47 | 1,478
Bipolar Disorder 46 | 666
Depressive disorder 46 | 409
Breast Neoplasms 45 | 445
Mammary Neoplasms 45 | 425
Pick disease 45 | 1,894
adrenocortical carcinoma 45 | 1,428
Neuropathy 43 | 261
Cerebrovascular disease 42 | 238
Liver Cirrhosis, Experimental 41 | 769
Toxic encephalopathy 40 | 141
esophageal adenocarcinoma 40 | 737
Down syndrome 39 | 499
tuberculosis 39 | 2,010
Heart disease 38 | 306
cutaneous lupus erythematosus 38 | 1,057
Adenoma 37 | 167
Obesity 37 | 678
Amyotrophic lateral sclerosis 36 | 451
Intellectual disability 36 | 1,016
Mental Depression 36 | 333
Neurodegenerative disease 36 | 414
Parkinson's disease 36 | 392
nasopharyngeal carcinoma 36 | 1,058
Endometriosis 35 | 540
Epilepsy 35 | 792
primary pancreatic ductal adenocarcinoma 35 | 1,109
Hypertension 34 | 396
Liver disease 34 | 237
Multiple Sclerosis 34 | 540
Neoplasm Invasiveness 34 | 161
Rheumatoid arthritis 34 | 1,191
Stomach Neoplasms 34 | 300
Vascular disease 34 | 319
Atopic dermatitis 33 | 952
group 4 medulloblastoma 33 | 1,855
Seizures 32 | 596
Arthritis 31 | 290
Major Depressive Disorder 31 | 301
acute quadriplegic myopathy 31 | 1,158
dermatomyositis 31 | 966
pancreatic ductal adenocarcinoma liver metastasis 31 | 1,962
Melanoma 30 | 711
Prostatic Neoplasms 30 | 495
Brain disease 29 | 96
Cell Transformation, Neoplastic 29 | 97
Liver cancer 29 | 604
Neoplasm Metastasis 29 | 168
Skin cancer 29 | 469
Dull intelligence 28 | 645
Hypersensitivity reaction type II disease 28 | 253
Low intelligence 28 | 645
Mental Retardation 28 | 645
Mental deficiency 28 | 645
Neoplastic Cell Transformation 28 | 89
Poor school performance 28 | 645
Unipolar Depression 28 | 250
Asthma 27 | 385
gastric carcinoma 27 | 807
Duchenne muscular dystrophy 26 | 601
spina bifida 26 | 1,074

Tissue

Endocrine System 289 | 18,159
Skin and soft tissues 285 | 17,230
Female tissues 283 | 17,400
Digestive Tract 281 | 17,369
Blood and immune system 272 | 16,909
Male tissues 268 | 17,142
Nervous System 261 | 16,725
Liver and Pancreas 254 | 16,750
Urinary Tract 252 | 16,678
Respiratory system 247 | 16,393
Cardiovascular System 226 | 15,192

Target Family

Non-IDG 231 | 12,091
Enzyme 38 | 4,145
Transcription Factor 32 | 1,400
Kinase 15 | 634
Transporter 4 | 473
GPCR 3 | 408
Nuclear Receptor 3 | 48
Epigenetic 2 | 242
Ion Channel 2 | 344

Compartment GO Term

Intermediate filament cytoskel... 330 | 330
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger protein 175 ZNF175 Tbio Transcription Factor -0.86533 8.35 88
Desmin DES Tbio Non-IDG -1.56068 36.6 991
CAP-Gly domain-containing linker protein 1 CLIP1 Tbio Non-IDG -2.54943 343.7 221
Neuromodulin GAP43 Tbio Non-IDG -2.93905 762.9 597
Choline O-acetyltransferase CHAT Tchem Enzyme -3.40175 2597.2 436
RNA binding protein fox-1 homolog 3 RBFOX3 Tbio Non-IDG -3.23341 1462.9 208
Scavenger receptor cysteine-rich type 1 protein M130 CD163 Tbio Non-IDG -2.93036 825.2 985
Calbindin CALB1 Tbio Non-IDG -3.31956 2149.9 287
Plakophilin-2 PKP2 Tbio Non-IDG -2.10355 135.3 243
Nesprin-2 SYNE2 Tbio Non-IDG -2.62747 380.6 39