Development Level

Tbio 196 | 10,625
Tdark 56 | 7,003
Tchem 54 | 1,890
Tclin 19 | 602

Collection

Eligible Kinase Proteins 2 | 134

IMPC Term

preweaning lethality, complete... 6 | 633
preweaning lethality, incomple... 6 | 260
decreased circulating alkaline... 4 | 41
decreased circulating insulin ... 4 | 75
decreased grip strength 4 | 123
abnormal behavior 3 | 226
abnormal lens morphology 3 | 73
abnormal retina morphology 3 | 100
decreased lean body mass 3 | 195
decreased total body fat amoun... 3 | 186
embryonic lethality prior to t... 3 | 187
improved glucose tolerance 3 | 56
increased circulating alkaline... 3 | 119
increased or absent threshold ... 3 | 128
abnormal QRS complex 2 | 25
abnormal bone structure 2 | 131
abnormal coat appearance 2 | 25
abnormal sleep behavior 2 | 63
cataract 2 | 26
decreased body weight 2 | 174
decreased bone mineral content 2 | 157
decreased circulating calcium ... 2 | 33
decreased heart weight 2 | 44
decreased rib number 2 | 59
hyperactivity 2 | 108
increased circulating HDL chol... 2 | 63
increased circulating choleste... 2 | 53
increased exploration in new e... 2 | 56
increased heart rate 2 | 17
increased lean body mass 2 | 107
limb grasping 2 | 35
short tibia 2 | 82
shortened RR interval 2 | 19
tremors 2 | 34
abnormal anxiety-related respo... 1 | 1
abnormal bone mineralization 1 | 55
abnormal coat/ hair morphology 1 | 18
abnormal coat/hair pigmentatio... 1 | 54
abnormal digit morphology 1 | 13
abnormal gait 1 | 51
abnormal head morphology 1 | 10
abnormal motor learning 1 | 4
abnormal optic disc morphology 1 | 10
abnormal retinal blood vessel ... 1 | 18
abnormal retinal vasculature m... 1 | 15
abnormal skin morphology 1 | 23
abnormal social/conspecific in... 1 | 3
abnormal spine curvature 1 | 7
abnormal spleen morphology 1 | 36
abnormal startle reflex 1 | 14
abnormal vocalization 1 | 21
abnormal whole-body plethysmog... 1 | 4
cardiovascular system phenotyp... 1 | 35
convulsive seizures 1 | 11
decreased CD8-positive, alpha-... 1 | 26
decreased T cell number 1 | 31
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 77
decreased circulating free fat... 1 | 39
decreased circulating glucose ... 1 | 121
decreased circulating phosphat... 1 | 15
decreased circulating serum al... 1 | 79
decreased circulating triglyce... 1 | 83
decreased follicular B cell nu... 1 | 4
decreased heart rate variabili... 1 | 11
decreased leukocyte cell numbe... 1 | 54
decreased mean corpuscular vol... 1 | 50
decreased pulmonary respirator... 1 | 4
decreased total retina thickne... 1 | 20
decreased vertical activity 1 | 22
embryonic lethality prior to o... 1 | 148
enlarged heart 1 | 111
hydrops fetalis 1 | 22
increased blood uric acid leve... 1 | 5
increased body length 1 | 20
increased body weight 1 | 42
increased bone mineral density 1 | 52
increased circulating chloride... 1 | 43
increased circulating magnesiu... 1 | 10
increased circulating serum al... 1 | 25
increased granulocyte number 1 | 8
increased grip strength 1 | 83
increased heart weight 1 | 37
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased respiratory quotient 1 | 12
increased rib number 1 | 41
increased tidal volume 1 | 1
male infertility 1 | 62
persistence of hyaloid vascula... 1 | 22
polycystic kidney 1 | 9
shortened ST segment 1 | 9
straub tail 1 | 26

Disease

psoriasis 159 | 6,685
Cancer 157 | 2,346
ovarian cancer 150 | 8,492
osteosarcoma 118 | 7,933
glioblastoma 112 | 5,572
lung cancer 110 | 4,473
medulloblastoma, large-cell 100 | 6,234
Breast cancer 87 | 3,099
atypical teratoid / rhabdoid tumor 83 | 4,369
malignant mesothelioma 78 | 3,163
pilocytic astrocytoma 77 | 3,086
non-small cell lung cancer 71 | 2,798
intraductal papillary-mucinous neoplasm (IPMN) 70 | 3,289
lung carcinoma 70 | 2,844
oligodendroglioma 70 | 2,849
lung adenocarcinoma 69 | 2,714
diabetes mellitus 68 | 1,663
invasive ductal carcinoma 68 | 2,950
intraductal papillary-mucinous adenoma (IPMA) 66 | 2,956
Carcinoma 62 | 2,147
pancreatic cancer 62 | 2,300
cystic fibrosis 61 | 1,670
interstitial cystitis 61 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 59 | 2,988
primitive neuroectodermal tumor 59 | 3,031
pediatric high grade glioma 58 | 2,712
ulcerative colitis 55 | 2,087
Alzheimer's disease 52 | 644
breast carcinoma 51 | 1,614
pituitary cancer 51 | 1,972
subependymal giant cell astrocytoma 50 | 2,287
ductal carcinoma in situ 48 | 1,745
posterior fossa group A ependymoma 48 | 1,511
colon cancer 46 | 1,475
Kidney disease 45 | 397
adrenocortical carcinoma 45 | 1,427
ependymoma 45 | 2,514
Pick disease 43 | 1,893
adult high grade glioma 43 | 2,148
Down syndrome 40 | 548
sonic hedgehog group medulloblastoma 40 | 1,482
Cerebrovascular disease 39 | 231
Mammary Neoplasms 38 | 410
group 3 medulloblastoma 38 | 2,254
Adenoma 37 | 165
Toxic encephalopathy 37 | 131
astrocytoma 37 | 1,493
esophageal adenocarcinoma 37 | 737
primary pancreatic ductal adenocarcinoma 37 | 1,271
Endometriosis 36 | 535
Heart disease 36 | 279
Neuropathy 36 | 210
astrocytic glioma 36 | 2,241
atypical teratoid/rhabdoid tumor 36 | 1,095
Vascular disease 35 | 281
tuberculosis 35 | 1,563
posterior fossa group B ependymoma 34 | 1,530
Multiple Sclerosis 33 | 498
Rheumatoid Arthritis 33 | 1,171
cutaneous lupus erythematosus 33 | 1,056
Amyotrophic Lateral Sclerosis 31 | 432
Liver disease 31 | 219
Neurodegenerative disease 31 | 383
Parkinson's disease 31 | 364
acute quadriplegic myopathy 31 | 1,157
group 4 medulloblastoma 31 | 1,875
nasopharyngeal carcinoma 31 | 1,056
Schizophrenia 30 | 503
dermatomyositis 30 | 967
Hypertension 29 | 293
Stomach Neoplasms 29 | 282
medulloblastoma 29 | 1,524
Arthritis 28 | 248
Atopic dermatitis 28 | 944
Neoplasm Metastasis 28 | 138
spina bifida 28 | 1,064
Duchenne muscular dystrophy 27 | 602
Obesity 27 | 616
Prostatic Neoplasms 27 | 471
Asthma 26 | 349
Hypersensitivity reaction type II disease 26 | 235
Multiple myeloma 26 | 1,328
Neoplasm Invasiveness 26 | 127
autosomal dominant Emery-Dreifuss muscular dystrophy 26 | 499
Inflammatory bowel disease 25 | 142
gastric carcinoma 25 | 832
Brain disease 24 | 84
Lung disease 24 | 136
Myopathy 24 | 128
Neoplastic Cell Transformation 24 | 81
pancreatic ductal adenocarcinoma liver metastasis 24 | 1,795
Liver carcinoma 23 | 217
Dementia 22 | 129
Epilepsy 21 | 346
Lung Neoplasms 21 | 171
Waldenstrons macroglobulinemia 21 | 765
juvenile dermatomyositis 21 | 1,189
non-small cell lung carcinoma 21 | 413
Atherosclerosis 20 | 275
Brain Ischemia 20 | 87

Tissue

Female tissues 312 | 18,647
Endocrine System 306 | 18,512
Nervous System 306 | 18,561
Digestive Tract 304 | 18,473
Skin and soft tissues 302 | 18,115
Urinary Tract 298 | 18,444
Liver and Pancreas 295 | 18,136
Cardiovascular System 294 | 17,958
Male tissues 292 | 17,969
Blood and immune system 288 | 17,995
Respiratory system 283 | 17,484

Target Family

Non-IDG 232 | 11,969
Enzyme 34 | 4,146
Transcription Factor 32 | 1,400
Kinase 15 | 634
GPCR 3 | 408
Transporter 3 | 473
Epigenetic 2 | 242
Ion Channel 2 | 341
Nuclear Receptor 2 | 48

Compartment GO Term

Intermediate filament cytoskel... 325 | 325
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,612 | 13,612
Intracellular part 13,475 | 13,475
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,353 | 10,353
Membrane 8,871 | 8,871
Organelle part 8,169 | 8,169
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,831 | 7,831
Nucleus 7,577 | 7,577
Membrane part 6,469 | 6,469
Cytosol 6,034 | 6,034
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,930 | 4,930
Extracellular region 4,607 | 4,607
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,874 | 3,874
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,592 | 2,592
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,530 | 1,530
Cell projection 1,425 | 1,425
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,092 | 1,092
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,084 | 1,084
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 988 | 988
Nucleoli 950 | 950
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 815 | 815
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 656 | 656
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Lamin tail domain-containing protein 1 LMNTD1 Tdark Non-IDG 0.00000 1.11 56
Keratin, type II cytoskeletal 2 oral KRT76 Tdark Non-IDG -0.28255 1.97 104
Tubulin beta-3 chain TUBB3 Tclin Non-IDG -2.04546 78.8 485
Zinc finger protein 175 ZNF175 Tbio Transcription Factor -0.86533 8.35 75
RNA binding protein fox-1 homolog 3 RBFOX3 Tbio Non-IDG -3.20483 1368.4 194
Epithelial cell adhesion molecule EPCAM Tbio Non-IDG -3.16288 1470.6 1441
NADPH-dependent diflavin oxidoreductase 1 NDOR1 Tbio Enzyme -0.71309 5.05 131
Alpha-methylacyl-CoA racemase AMACR Tbio Enzyme -2.45535 296.1 443
SAP30-binding protein SAP30BP Tbio Non-IDG -1.42951 29.3 135
Inositol hexakisphosphate kinase 2 IP6K2 Tbio Kinase -1.38718 25.6 118