Development Level

Tbio 196 | 10,625
Tdark 56 | 7,003
Tchem 54 | 1,890
Tclin 19 | 602

Collection

Eligible Kinase Proteins 2 | 134

IMPC Term

preweaning lethality, complete... 6 | 633
preweaning lethality, incomple... 6 | 260
decreased circulating alkaline... 4 | 41
decreased circulating insulin ... 4 | 75
decreased grip strength 4 | 123
abnormal behavior 3 | 226
abnormal lens morphology 3 | 73
abnormal retina morphology 3 | 100
decreased lean body mass 3 | 195
decreased total body fat amoun... 3 | 186
embryonic lethality prior to t... 3 | 187
improved glucose tolerance 3 | 56
increased circulating alkaline... 3 | 119
increased or absent threshold ... 3 | 128
abnormal QRS complex 2 | 25
abnormal bone structure 2 | 131
abnormal coat appearance 2 | 25
abnormal sleep behavior 2 | 63
cataract 2 | 26
decreased body weight 2 | 174
decreased bone mineral content 2 | 157
decreased circulating calcium ... 2 | 33
decreased heart weight 2 | 44
decreased rib number 2 | 59
hyperactivity 2 | 108
increased circulating HDL chol... 2 | 63
increased circulating choleste... 2 | 53
increased exploration in new e... 2 | 56
increased heart rate 2 | 17
increased lean body mass 2 | 107
limb grasping 2 | 35
short tibia 2 | 82
shortened RR interval 2 | 19
tremors 2 | 34
abnormal anxiety-related respo... 1 | 1
abnormal bone mineralization 1 | 55
abnormal coat/ hair morphology 1 | 18
abnormal coat/hair pigmentatio... 1 | 54
abnormal digit morphology 1 | 13
abnormal gait 1 | 51
abnormal head morphology 1 | 10
abnormal motor learning 1 | 4
abnormal optic disc morphology 1 | 10
abnormal retinal blood vessel ... 1 | 18
abnormal retinal vasculature m... 1 | 15
abnormal skin morphology 1 | 23
abnormal social/conspecific in... 1 | 3
abnormal spine curvature 1 | 7
abnormal spleen morphology 1 | 36
abnormal startle reflex 1 | 14
abnormal vocalization 1 | 21
abnormal whole-body plethysmog... 1 | 4
cardiovascular system phenotyp... 1 | 35
convulsive seizures 1 | 11
decreased CD8-positive, alpha-... 1 | 26
decreased T cell number 1 | 31
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 77
decreased circulating free fat... 1 | 39
decreased circulating glucose ... 1 | 121
decreased circulating phosphat... 1 | 15
decreased circulating serum al... 1 | 79
decreased circulating triglyce... 1 | 83
decreased follicular B cell nu... 1 | 4
decreased heart rate variabili... 1 | 11
decreased leukocyte cell numbe... 1 | 54
decreased mean corpuscular vol... 1 | 50
decreased pulmonary respirator... 1 | 4
decreased total retina thickne... 1 | 20
decreased vertical activity 1 | 22
embryonic lethality prior to o... 1 | 148
enlarged heart 1 | 111
hydrops fetalis 1 | 22
increased blood uric acid leve... 1 | 5
increased body length 1 | 20
increased body weight 1 | 42
increased bone mineral density 1 | 52
increased circulating chloride... 1 | 43
increased circulating magnesiu... 1 | 10
increased circulating serum al... 1 | 25
increased granulocyte number 1 | 8
increased grip strength 1 | 83
increased heart weight 1 | 37
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased respiratory quotient 1 | 12
increased rib number 1 | 41
increased tidal volume 1 | 1
male infertility 1 | 62
persistence of hyaloid vascula... 1 | 22
polycystic kidney 1 | 9
shortened ST segment 1 | 9
straub tail 1 | 26

Disease

psoriasis 159 | 6,685
Cancer 157 | 2,346
ovarian cancer 149 | 8,484
osteosarcoma 118 | 7,933
glioblastoma 112 | 5,572
lung cancer 110 | 4,466
medulloblastoma, large-cell 100 | 6,234
Breast cancer 86 | 3,094
atypical teratoid / rhabdoid tumor 83 | 4,369
malignant mesothelioma 78 | 3,162
pilocytic astrocytoma 77 | 3,086
non-small cell lung cancer 71 | 2,798
intraductal papillary-mucinous neoplasm (IPMN) 70 | 3,289
lung carcinoma 70 | 2,844
oligodendroglioma 70 | 2,849
lung adenocarcinoma 69 | 2,713
diabetes mellitus 68 | 1,663
invasive ductal carcinoma 68 | 2,950
intraductal papillary-mucinous adenoma (IPMA) 66 | 2,956
Carcinoma 62 | 2,147
pancreatic cancer 62 | 2,300
cystic fibrosis 61 | 1,665
interstitial cystitis 61 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 59 | 2,988
primitive neuroectodermal tumor 59 | 3,031
pediatric high grade glioma 58 | 2,712
ulcerative colitis 55 | 2,087
Alzheimer's disease 52 | 644
breast carcinoma 51 | 1,614
pituitary cancer 51 | 1,972
subependymal giant cell astrocytoma 50 | 2,287
ductal carcinoma in situ 48 | 1,745
posterior fossa group A ependymoma 48 | 1,511
colon cancer 46 | 1,475
Kidney disease 45 | 396
adrenocortical carcinoma 45 | 1,427
ependymoma 45 | 2,514
Pick disease 43 | 1,893
adult high grade glioma 43 | 2,148
Down syndrome 40 | 548
sonic hedgehog group medulloblastoma 40 | 1,482
Cerebrovascular disease 39 | 231
Mammary Neoplasms 38 | 410
group 3 medulloblastoma 38 | 2,254
Adenoma 37 | 165
Toxic encephalopathy 37 | 131
astrocytoma 37 | 1,493
esophageal adenocarcinoma 37 | 737
primary pancreatic ductal adenocarcinoma 37 | 1,271
Endometriosis 36 | 535
Heart disease 36 | 279
Neuropathy 36 | 210
astrocytic glioma 36 | 2,241
atypical teratoid/rhabdoid tumor 36 | 1,095
Vascular disease 35 | 281
tuberculosis 35 | 1,557
posterior fossa group B ependymoma 34 | 1,530
Multiple Sclerosis 33 | 498
Rheumatoid Arthritis 33 | 1,160
cutaneous lupus erythematosus 33 | 1,056
Amyotrophic Lateral Sclerosis 31 | 431
Liver disease 31 | 219
Neurodegenerative disease 31 | 383
Parkinson's disease 31 | 364
acute quadriplegic myopathy 31 | 1,157
group 4 medulloblastoma 31 | 1,875
nasopharyngeal carcinoma 31 | 1,056
dermatomyositis 30 | 933
Schizophrenia 29 | 501
Stomach Neoplasms 29 | 282
medulloblastoma 29 | 1,524
Arthritis 28 | 248
Atopic dermatitis 28 | 944
Hypertension 28 | 287
Neoplasm Metastasis 28 | 138
spina bifida 28 | 1,064
Duchenne muscular dystrophy 27 | 602
Obesity 27 | 616
Prostatic Neoplasms 27 | 471
Asthma 26 | 349
Hypersensitivity reaction type II disease 26 | 235
Multiple myeloma 26 | 1,327
Neoplasm Invasiveness 26 | 127
autosomal dominant Emery-Dreifuss muscular dystrophy 26 | 499
Inflammatory bowel disease 25 | 142
gastric carcinoma 25 | 832
Brain disease 24 | 83
Myopathy 24 | 128
Neoplastic Cell Transformation 24 | 81
pancreatic ductal adenocarcinoma liver metastasis 24 | 1,795
Liver carcinoma 23 | 217
Lung disease 23 | 132
Dementia 22 | 129
Epilepsy 21 | 346
Lung Neoplasms 21 | 171
Waldenstrons macroglobulinemia 21 | 765
juvenile dermatomyositis 21 | 1,189
non-small cell lung carcinoma 21 | 413
Atherosclerosis 20 | 275
Brain Ischemia 20 | 87

Tissue

Female tissues 312 | 18,647
Endocrine System 306 | 18,512
Nervous System 306 | 18,561
Digestive Tract 304 | 18,473
Skin and soft tissues 302 | 18,115
Urinary Tract 298 | 18,444
Liver and Pancreas 295 | 18,136
Cardiovascular System 294 | 17,958
Male tissues 292 | 17,969
Blood and immune system 288 | 17,995
Respiratory system 283 | 17,484

Target Family

Non-IDG 232 | 11,971
Enzyme 34 | 4,146
Transcription Factor 32 | 1,400
Kinase 15 | 634
GPCR 3 | 406
Transporter 3 | 473
Epigenetic 2 | 242
Ion Channel 2 | 341
Nuclear Receptor 2 | 48

Compartment GO Term

Intermediate filament cytoskel... 325 | 325
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.11560 13094.7 961
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
Retinaldehyde-binding protein 1 RLBP1 Tbio Non-IDG -2.12314 137.8 95
Glial cell line-derived neurotrophic factor GDNF Tbio Non-IDG -3.30206 2301.5 303
Mucin-1 MUC1 Tbio Non-IDG -3.49560 3532.0 1851
Keratin, type II cytoskeletal 3 KRT3 Tbio Non-IDG -2.12849 126.8 100
Neurofilament heavy polypeptide NEFH Tbio Non-IDG -2.73883 563.3 681
Desmoplakin DSP Tbio Non-IDG -2.90088 786.5 167
Myelin basic protein MBP Tbio Non-IDG -3.69577 5257.0 715
Filensin BFSP1 Tbio Non-IDG -2.08549 124.5 154