Development Level

Tbio 185 | 11,445
Tdark 47 | 6,588
Tchem 39 | 1,598
Tclin 22 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, incomple... 13 | 499
preweaning lethality, complete... 11 | 979
decreased circulating alkaline... 4 | 46
decreased circulating insulin ... 4 | 76
enlarged heart 4 | 210
abnormal behavior 3 | 298
abnormal seminal vesicle morph... 3 | 114
decreased total body fat amoun... 3 | 207
embryonic lethality prior to t... 3 | 278
increased startle reflex 3 | 112
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
abnormal heart morphology 2 | 162
abnormal lens morphology 2 | 81
abnormal retina morphology 2 | 71
cataract 2 | 92
decreased body weight 2 | 161
decreased circulating HDL chol... 2 | 68
decreased circulating calcium ... 2 | 36
decreased circulating choleste... 2 | 93
decreased coping response 2 | 8
decreased grip strength 2 | 116
decreased leukocyte cell numbe... 2 | 73
decreased lymphocyte cell numb... 2 | 83
decreased vertical activity 2 | 208
hyperactivity 2 | 148
improved glucose tolerance 2 | 79
increased blood urea nitrogen ... 2 | 48
increased body length 2 | 32
increased circulating HDL chol... 2 | 80
increased circulating choleste... 2 | 66
increased total body fat amoun... 2 | 134
limb grasping 2 | 41
short tibia 2 | 97
abnormal bone mineralization 1 | 38
abnormal coat appearance 1 | 31
abnormal coat- hair morphology 1 | 19
abnormal digit morphology 1 | 10
abnormal eye morphology 1 | 68
abnormal gait 1 | 69
abnormal head morphology 1 | 10
abnormal kidney morphology 1 | 65
abnormal placenta size 1 | 20
abnormal sleep behavior 1 | 70
abnormal spine curvature 1 | 9
abnormal startle reflex 1 | 15
abnormal vertebrae morphology 1 | 18
abnormal vocalization 1 | 21
absent vibrissae 1 | 12
cardiovascular system phenotyp... 1 | 36
convulsive seizures 1 | 13
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating free fat... 1 | 31
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased heart rate variabili... 1 | 13
decreased lean body mass 1 | 135
decreased startle reflex 1 | 75
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged uterus 1 | 11
hypoactivity 1 | 132
increased blood uric acid leve... 1 | 5
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating iron lev... 1 | 30
increased circulating magnesiu... 1 | 10
increased circulating phosphat... 1 | 26
increased circulating serum al... 1 | 22
increased exploration in new e... 1 | 8
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
male infertility 1 | 123
mammalian phenotype 1 | 17
pallor 1 | 34
polycystic kidney 1 | 15
premature death 1 | 5
prenatal lethality prior to he... 1 | 87
shortened RR interval 1 | 17
small spleen 1 | 19
small superior vagus ganglion 1 | 74
tremors 1 | 39

Disease

Carcinoma 197 | 11,493
Cancer 160 | 2,499
psoriasis 150 | 6,694
ovarian cancer 133 | 8,520
glioblastoma 115 | 5,792
lung cancer 110 | 4,740
ependymoma 101 | 4,679
Breast cancer 100 | 3,578
osteosarcoma 98 | 7,950
atypical teratoid / rhabdoid tumor 97 | 5,112
medulloblastoma, large-cell 91 | 6,241
malignant mesothelioma 83 | 3,232
Astrocytoma, Pilocytic 80 | 3,081
Schizophrenia 77 | 1,160
adult high grade glioma 73 | 3,801
lung carcinoma 72 | 2,843
lung adenocarcinoma 71 | 2,716
non-small cell lung cancer 70 | 2,890
group 3 medulloblastoma 68 | 4,104
diabetes mellitus 67 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 67 | 3,291
oligodendroglioma 66 | 2,850
invasive ductal carcinoma 65 | 2,951
intraductal papillary-mucinous adenoma (IPMA) 64 | 2,955
interstitial cystitis 62 | 2,312
pancreatic cancer 62 | 2,398
cystic fibrosis 60 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 59 | 2,989
Alzheimer's disease 58 | 658
pituitary cancer 55 | 1,972
Autosomal recessive predisposition 54 | 1,442
breast carcinoma 54 | 1,638
primitive neuroectodermal tumor 53 | 3,035
Kidney cancer 50 | 2,613
astrocytic glioma 50 | 2,597
ductal carcinoma in situ 49 | 1,745
subependymal giant cell astrocytoma 49 | 2,287
ulcerative colitis 48 | 1,819
Kidney disease 47 | 430
Bipolar Disorder 43 | 666
Breast Neoplasms 43 | 445
Depressive disorder 43 | 409
Mammary Neoplasms 43 | 425
adrenocortical carcinoma 43 | 1,428
colon cancer 43 | 1,478
Cerebrovascular disease 42 | 238
Neuropathy 42 | 261
Liver Cirrhosis, Experimental 41 | 769
Pick disease 40 | 1,894
Toxic encephalopathy 40 | 141
Down syndrome 39 | 499
Adenoma 37 | 167
Heart disease 37 | 306
Endometriosis 35 | 540
Neurodegenerative disease 35 | 414
Obesity 35 | 678
esophageal adenocarcinoma 35 | 737
Epilepsy 34 | 792
Intellectual disability 34 | 1,016
Mental Depression 34 | 333
Stomach Neoplasms 34 | 300
cutaneous lupus erythematosus 34 | 1,057
nasopharyngeal carcinoma 34 | 1,058
tuberculosis 34 | 2,010
Hypertension 33 | 396
Liver disease 33 | 237
Multiple Sclerosis 33 | 540
Neoplasm Invasiveness 33 | 161
Parkinson's disease 33 | 392
Vascular disease 33 | 319
primary pancreatic ductal adenocarcinoma 32 | 1,109
Amyotrophic lateral sclerosis 31 | 451
Rheumatoid arthritis 31 | 1,191
Seizures 31 | 596
Arthritis 30 | 290
Atopic dermatitis 30 | 952
Prostatic Neoplasms 30 | 495
group 4 medulloblastoma 30 | 1,855
Brain disease 29 | 96
Neoplasm Metastasis 29 | 168
Cell Transformation, Neoplastic 28 | 97
Dull intelligence 28 | 645
Hypersensitivity reaction type II disease 28 | 253
Low intelligence 28 | 645
Major Depressive Disorder 28 | 301
Mental Retardation 28 | 645
Mental deficiency 28 | 645
Poor school performance 28 | 645
pancreatic ductal adenocarcinoma liver metastasis 28 | 1,962
Melanoma 27 | 711
Neoplastic Cell Transformation 27 | 89
Skin cancer 27 | 469
dermatomyositis 27 | 966
gastric carcinoma 27 | 807
Asthma 26 | 385
Dementia 26 | 175
Lung disease 26 | 142
acute quadriplegic myopathy 26 | 1,158
Duchenne muscular dystrophy 25 | 601
Inflammatory bowel disease 25 | 151

Tissue

Endocrine System 252 | 18,159
Skin and soft tissues 248 | 17,230
Female tissues 246 | 17,400
Digestive Tract 244 | 17,369
Blood and immune system 235 | 16,909
Male tissues 231 | 17,142
Nervous System 225 | 16,725
Liver and Pancreas 217 | 16,750
Urinary Tract 216 | 16,678
Respiratory system 210 | 16,393
Cardiovascular System 190 | 15,192

Target Family

Non-IDG 212 | 12,091
Transcription Factor 30 | 1,400
Enzyme 29 | 4,145
Kinase 13 | 634
GPCR 3 | 408
Transporter 3 | 473
Nuclear Receptor 2 | 48
Ion Channel 1 | 344

Compartment GO Term

Intermediate filament 293 | 293
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Desmin DES Tbio Non-IDG -1.56068 36.6 991
CAP-Gly domain-containing linker protein 1 CLIP1 Tbio Non-IDG -2.54943 343.7 221
Neuromodulin GAP43 Tbio Non-IDG -2.93905 762.9 597
Choline O-acetyltransferase CHAT Tchem Enzyme -3.40175 2597.2 436
RNA binding protein fox-1 homolog 3 RBFOX3 Tbio Non-IDG -3.23341 1462.9 208
Scavenger receptor cysteine-rich type 1 protein M130 CD163 Tbio Non-IDG -2.93036 825.2 985
Calbindin CALB1 Tbio Non-IDG -3.31956 2149.9 287
Plakophilin-2 PKP2 Tbio Non-IDG -2.10355 135.3 243
Paired box protein Pax-2 PAX2 Tbio Transcription Factor -2.68609 492.0 349
High affinity nerve growth factor receptor NTRK1 Tclin Kinase -3.05841 1050.9 1092