Development Level

Tbio 164 | 10,625
Tdark 51 | 7,003
Tchem 50 | 1,890
Tclin 19 | 602

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 6 | 633
preweaning lethality, incomple... 6 | 260
decreased circulating alkaline... 4 | 41
decreased circulating insulin ... 4 | 75
abnormal behavior 3 | 226
abnormal lens morphology 3 | 73
abnormal retina morphology 3 | 100
decreased grip strength 3 | 123
embryonic lethality prior to t... 3 | 187
increased circulating alkaline... 3 | 119
increased or absent threshold ... 3 | 128
abnormal QRS complex 2 | 25
abnormal bone structure 2 | 131
abnormal coat appearance 2 | 25
abnormal sleep behavior 2 | 63
cataract 2 | 26
decreased body weight 2 | 174
decreased bone mineral content 2 | 157
decreased circulating calcium ... 2 | 33
decreased lean body mass 2 | 195
decreased total body fat amoun... 2 | 186
hyperactivity 2 | 108
improved glucose tolerance 2 | 56
increased circulating HDL chol... 2 | 63
increased circulating choleste... 2 | 53
increased exploration in new e... 2 | 56
limb grasping 2 | 35
short tibia 2 | 82
tremors 2 | 34
abnormal anxiety-related respo... 1 | 1
abnormal bone mineralization 1 | 55
abnormal coat/ hair morphology 1 | 18
abnormal coat/hair pigmentatio... 1 | 54
abnormal digit morphology 1 | 13
abnormal gait 1 | 51
abnormal head morphology 1 | 10
abnormal motor learning 1 | 4
abnormal optic disc morphology 1 | 10
abnormal retinal blood vessel ... 1 | 18
abnormal retinal vasculature m... 1 | 15
abnormal social/conspecific in... 1 | 3
abnormal spine curvature 1 | 7
abnormal startle reflex 1 | 14
abnormal vocalization 1 | 21
abnormal whole-body plethysmog... 1 | 4
cardiovascular system phenotyp... 1 | 35
convulsive seizures 1 | 11
decreased CD8-positive, alpha-... 1 | 26
decreased T cell number 1 | 31
decreased blood urea nitrogen ... 1 | 31
decreased circulating free fat... 1 | 39
decreased circulating glucose ... 1 | 121
decreased circulating phosphat... 1 | 15
decreased circulating triglyce... 1 | 83
decreased follicular B cell nu... 1 | 4
decreased heart rate variabili... 1 | 11
decreased heart weight 1 | 44
decreased leukocyte cell numbe... 1 | 54
decreased mean corpuscular vol... 1 | 50
decreased pulmonary respirator... 1 | 4
decreased rib number 1 | 59
decreased total retina thickne... 1 | 20
embryonic lethality prior to o... 1 | 148
enlarged heart 1 | 111
hydrops fetalis 1 | 22
increased blood uric acid leve... 1 | 5
increased body length 1 | 20
increased body weight 1 | 42
increased bone mineral density 1 | 52
increased circulating chloride... 1 | 43
increased circulating magnesiu... 1 | 10
increased circulating serum al... 1 | 25
increased granulocyte number 1 | 8
increased heart rate 1 | 17
increased heart weight 1 | 37
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased respiratory quotient 1 | 12
increased tidal volume 1 | 1
male infertility 1 | 62
persistence of hyaloid vascula... 1 | 22
polycystic kidney 1 | 9
shortened RR interval 1 | 19
straub tail 1 | 26

Disease

Cancer 150 | 2,346
psoriasis 147 | 6,685
ovarian cancer 122 | 8,484
glioblastoma 102 | 5,572
lung cancer 101 | 4,466
osteosarcoma 94 | 7,933
medulloblastoma, large-cell 84 | 6,234
Breast cancer 75 | 3,094
pilocytic astrocytoma 73 | 3,086
malignant mesothelioma 72 | 3,162
non-small cell lung cancer 69 | 2,798
lung adenocarcinoma 67 | 2,713
atypical teratoid / rhabdoid tumor 66 | 4,369
diabetes mellitus 66 | 1,663
lung carcinoma 65 | 2,844
intraductal papillary-mucinous neoplasm (IPMN) 64 | 3,289
oligodendroglioma 63 | 2,849
intraductal papillary-mucinous adenoma (IPMA) 61 | 2,956
invasive ductal carcinoma 61 | 2,950
cystic fibrosis 58 | 1,665
interstitial cystitis 57 | 2,299
pancreatic cancer 57 | 2,300
intraductal papillary-mucinous carcinoma (IPMC) 56 | 2,988
pediatric high grade glioma 56 | 2,712
Carcinoma 51 | 2,147
ulcerative colitis 51 | 2,087
Alzheimer's disease 50 | 644
pituitary cancer 50 | 1,972
primitive neuroectodermal tumor 49 | 3,031
breast carcinoma 47 | 1,614
ductal carcinoma in situ 46 | 1,745
subependymal giant cell astrocytoma 46 | 2,287
Kidney disease 44 | 396
posterior fossa group A ependymoma 44 | 1,511
adrenocortical carcinoma 41 | 1,427
colon cancer 40 | 1,475
Cerebrovascular disease 39 | 231
Pick disease 38 | 1,893
ependymoma 38 | 2,514
Down syndrome 37 | 548
Mammary Neoplasms 37 | 410
Toxic encephalopathy 37 | 131
Adenoma 36 | 165
Endometriosis 36 | 535
Neuropathy 36 | 210
Heart disease 35 | 279
Vascular disease 35 | 281
adult high grade glioma 35 | 2,148
primary pancreatic ductal adenocarcinoma 35 | 1,271
sonic hedgehog group medulloblastoma 35 | 1,482
astrocytoma 34 | 1,493
atypical teratoid/rhabdoid tumor 34 | 1,095
esophageal adenocarcinoma 33 | 737
group 3 medulloblastoma 33 | 2,254
Multiple Sclerosis 32 | 498
cutaneous lupus erythematosus 32 | 1,056
Liver disease 31 | 219
astrocytic glioma 31 | 2,241
posterior fossa group B ependymoma 31 | 1,530
tuberculosis 31 | 1,557
Neurodegenerative disease 30 | 383
nasopharyngeal carcinoma 30 | 1,056
Amyotrophic Lateral Sclerosis 29 | 431
Parkinson's disease 29 | 364
Stomach Neoplasms 29 | 282
Arthritis 28 | 248
Atopic dermatitis 28 | 944
Hypertension 28 | 287
Neoplasm Metastasis 28 | 138
Rheumatoid Arthritis 28 | 1,160
Schizophrenia 28 | 501
Obesity 27 | 616
Prostatic Neoplasms 27 | 471
Hypersensitivity reaction type II disease 26 | 235
Neoplasm Invasiveness 26 | 127
group 4 medulloblastoma 26 | 1,875
Asthma 25 | 349
Duchenne muscular dystrophy 25 | 602
Inflammatory bowel disease 25 | 142
dermatomyositis 25 | 933
gastric carcinoma 25 | 832
Brain disease 24 | 83
Myopathy 24 | 128
Neoplastic Cell Transformation 24 | 81
acute quadriplegic myopathy 24 | 1,157
medulloblastoma 24 | 1,524
Liver carcinoma 23 | 217
Lung disease 23 | 132
autosomal dominant Emery-Dreifuss muscular dystrophy 23 | 499
spina bifida 23 | 1,064
Dementia 22 | 129
Epilepsy 21 | 346
Lung Neoplasms 21 | 171
non-small cell lung carcinoma 21 | 413
pancreatic ductal adenocarcinoma liver metastasis 21 | 1,795
Atherosclerosis 20 | 275
Brain Ischemia 20 | 87
Eye disease 19 | 55
Multiple myeloma 19 | 1,327
Peripheral Neuropathy 19 | 303

Tissue

Female tissues 271 | 18,647
Endocrine System 265 | 18,512
Nervous System 265 | 18,561
Digestive Tract 263 | 18,473
Skin and soft tissues 261 | 18,115
Urinary Tract 257 | 18,444
Liver and Pancreas 254 | 18,136
Cardiovascular System 253 | 17,958
Male tissues 251 | 17,969
Blood and immune system 248 | 17,995
Respiratory system 243 | 17,484

Target Family

Non-IDG 208 | 11,971
Transcription Factor 29 | 1,400
Enzyme 26 | 4,146
Kinase 12 | 634
GPCR 3 | 406
Transporter 3 | 473
Nuclear Receptor 2 | 48
Ion Channel 1 | 341

Compartment GO Term

Intermediate filament 284 | 284
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.11560 13094.7 961
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
Retinaldehyde-binding protein 1 RLBP1 Tbio Non-IDG -2.12314 137.8 95
Glial cell line-derived neurotrophic factor GDNF Tbio Non-IDG -3.30206 2301.5 303
Mucin-1 MUC1 Tbio Non-IDG -3.49560 3532.0 1851
Keratin, type II cytoskeletal 3 KRT3 Tbio Non-IDG -2.12849 126.8 100
Neurofilament heavy polypeptide NEFH Tbio Non-IDG -2.73883 563.3 681
Desmoplakin DSP Tbio Non-IDG -2.90088 786.5 167
Myelin basic protein MBP Tbio Non-IDG -3.69577 5257.0 715
Filensin BFSP1 Tbio Non-IDG -2.08549 124.5 154