Development Level

Tbio 164 | 10,625
Tdark 51 | 7,003
Tchem 50 | 1,890
Tclin 19 | 602

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 6 | 633
preweaning lethality, incomple... 6 | 260
decreased circulating alkaline... 4 | 41
decreased circulating insulin ... 4 | 75
abnormal behavior 3 | 226
abnormal lens morphology 3 | 73
abnormal retina morphology 3 | 100
decreased grip strength 3 | 123
embryonic lethality prior to t... 3 | 187
increased circulating alkaline... 3 | 119
increased or absent threshold ... 3 | 128
abnormal QRS complex 2 | 25
abnormal bone structure 2 | 131
abnormal coat appearance 2 | 25
abnormal sleep behavior 2 | 63
cataract 2 | 26
decreased body weight 2 | 174
decreased bone mineral content 2 | 157
decreased circulating calcium ... 2 | 33
decreased lean body mass 2 | 195
decreased total body fat amoun... 2 | 186
hyperactivity 2 | 108
improved glucose tolerance 2 | 56
increased circulating HDL chol... 2 | 63
increased circulating choleste... 2 | 53
increased exploration in new e... 2 | 56
limb grasping 2 | 35
short tibia 2 | 82
tremors 2 | 34
abnormal anxiety-related respo... 1 | 1
abnormal bone mineralization 1 | 55
abnormal coat/ hair morphology 1 | 18
abnormal coat/hair pigmentatio... 1 | 54
abnormal digit morphology 1 | 13
abnormal gait 1 | 51
abnormal head morphology 1 | 10
abnormal motor learning 1 | 4
abnormal optic disc morphology 1 | 10
abnormal retinal blood vessel ... 1 | 18
abnormal retinal vasculature m... 1 | 15
abnormal social/conspecific in... 1 | 3
abnormal spine curvature 1 | 7
abnormal startle reflex 1 | 14
abnormal vocalization 1 | 21
abnormal whole-body plethysmog... 1 | 4
cardiovascular system phenotyp... 1 | 35
convulsive seizures 1 | 11
decreased CD8-positive, alpha-... 1 | 26
decreased T cell number 1 | 31
decreased blood urea nitrogen ... 1 | 31
decreased circulating free fat... 1 | 39
decreased circulating glucose ... 1 | 121
decreased circulating phosphat... 1 | 15
decreased circulating triglyce... 1 | 83
decreased follicular B cell nu... 1 | 4
decreased heart rate variabili... 1 | 11
decreased heart weight 1 | 44
decreased leukocyte cell numbe... 1 | 54
decreased mean corpuscular vol... 1 | 50
decreased pulmonary respirator... 1 | 4
decreased rib number 1 | 59
decreased total retina thickne... 1 | 20
embryonic lethality prior to o... 1 | 148
enlarged heart 1 | 111
hydrops fetalis 1 | 22
increased blood uric acid leve... 1 | 5
increased body length 1 | 20
increased body weight 1 | 42
increased bone mineral density 1 | 52
increased circulating chloride... 1 | 43
increased circulating magnesiu... 1 | 10
increased circulating serum al... 1 | 25
increased granulocyte number 1 | 8
increased heart rate 1 | 17
increased heart weight 1 | 37
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased respiratory quotient 1 | 12
increased tidal volume 1 | 1
male infertility 1 | 62
persistence of hyaloid vascula... 1 | 22
polycystic kidney 1 | 9
shortened RR interval 1 | 19
straub tail 1 | 26

Disease

Cancer 150 | 2,346
psoriasis 147 | 6,685
ovarian cancer 123 | 8,492
glioblastoma 102 | 5,572
lung cancer 101 | 4,473
osteosarcoma 94 | 7,933
medulloblastoma, large-cell 84 | 6,234
Breast cancer 76 | 3,099
pilocytic astrocytoma 73 | 3,086
malignant mesothelioma 72 | 3,163
non-small cell lung cancer 69 | 2,798
lung adenocarcinoma 67 | 2,714
atypical teratoid / rhabdoid tumor 66 | 4,369
diabetes mellitus 66 | 1,663
lung carcinoma 65 | 2,844
intraductal papillary-mucinous neoplasm (IPMN) 64 | 3,289
oligodendroglioma 63 | 2,849
intraductal papillary-mucinous adenoma (IPMA) 61 | 2,956
invasive ductal carcinoma 61 | 2,950
cystic fibrosis 58 | 1,670
interstitial cystitis 57 | 2,299
pancreatic cancer 57 | 2,300
intraductal papillary-mucinous carcinoma (IPMC) 56 | 2,988
pediatric high grade glioma 56 | 2,712
Carcinoma 51 | 2,147
ulcerative colitis 51 | 2,087
Alzheimer's disease 50 | 644
pituitary cancer 50 | 1,972
primitive neuroectodermal tumor 49 | 3,031
breast carcinoma 47 | 1,614
ductal carcinoma in situ 46 | 1,745
subependymal giant cell astrocytoma 46 | 2,287
Kidney disease 44 | 397
posterior fossa group A ependymoma 44 | 1,511
adrenocortical carcinoma 41 | 1,427
colon cancer 40 | 1,475
Cerebrovascular disease 39 | 231
Pick disease 38 | 1,893
ependymoma 38 | 2,514
Down syndrome 37 | 548
Mammary Neoplasms 37 | 410
Toxic encephalopathy 37 | 131
Adenoma 36 | 165
Endometriosis 36 | 535
Neuropathy 36 | 210
Heart disease 35 | 279
Vascular disease 35 | 281
adult high grade glioma 35 | 2,148
primary pancreatic ductal adenocarcinoma 35 | 1,271
sonic hedgehog group medulloblastoma 35 | 1,482
astrocytoma 34 | 1,493
atypical teratoid/rhabdoid tumor 34 | 1,095
esophageal adenocarcinoma 33 | 737
group 3 medulloblastoma 33 | 2,254
Multiple Sclerosis 32 | 498
cutaneous lupus erythematosus 32 | 1,056
Liver disease 31 | 219
astrocytic glioma 31 | 2,241
posterior fossa group B ependymoma 31 | 1,530
tuberculosis 31 | 1,563
Neurodegenerative disease 30 | 383
nasopharyngeal carcinoma 30 | 1,056
Amyotrophic Lateral Sclerosis 29 | 432
Hypertension 29 | 293
Parkinson's disease 29 | 364
Stomach Neoplasms 29 | 282
Arthritis 28 | 248
Atopic dermatitis 28 | 944
Neoplasm Metastasis 28 | 138
Rheumatoid Arthritis 28 | 1,171
Schizophrenia 28 | 503
Obesity 27 | 616
Prostatic Neoplasms 27 | 471
Hypersensitivity reaction type II disease 26 | 235
Neoplasm Invasiveness 26 | 127
group 4 medulloblastoma 26 | 1,875
Asthma 25 | 349
Duchenne muscular dystrophy 25 | 602
Inflammatory bowel disease 25 | 142
dermatomyositis 25 | 967
gastric carcinoma 25 | 832
Brain disease 24 | 84
Lung disease 24 | 136
Myopathy 24 | 128
Neoplastic Cell Transformation 24 | 81
acute quadriplegic myopathy 24 | 1,157
medulloblastoma 24 | 1,524
Liver carcinoma 23 | 217
autosomal dominant Emery-Dreifuss muscular dystrophy 23 | 499
spina bifida 23 | 1,064
Dementia 22 | 129
Epilepsy 21 | 346
Lung Neoplasms 21 | 171
non-small cell lung carcinoma 21 | 413
pancreatic ductal adenocarcinoma liver metastasis 21 | 1,795
Atherosclerosis 20 | 275
Brain Ischemia 20 | 87
Squamous cell carcinoma 20 | 96
Multiple myeloma 19 | 1,328
Peripheral Neuropathy 19 | 303

Tissue

Female tissues 271 | 18,647
Endocrine System 265 | 18,512
Nervous System 265 | 18,561
Digestive Tract 263 | 18,473
Skin and soft tissues 261 | 18,115
Urinary Tract 257 | 18,444
Liver and Pancreas 254 | 18,136
Cardiovascular System 253 | 17,958
Male tissues 251 | 17,969
Blood and immune system 248 | 17,995
Respiratory system 243 | 17,484

Target Family

Non-IDG 208 | 11,969
Transcription Factor 29 | 1,400
Enzyme 26 | 4,146
Kinase 12 | 634
GPCR 3 | 408
Transporter 3 | 473
Nuclear Receptor 2 | 48
Ion Channel 1 | 341

Compartment GO Term

Intermediate filament 284 | 284
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,612 | 13,612
Intracellular part 13,475 | 13,475
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,353 | 10,353
Membrane 8,871 | 8,871
Organelle part 8,169 | 8,169
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,831 | 7,831
Nucleus 7,577 | 7,577
Membrane part 6,469 | 6,469
Cytosol 6,034 | 6,034
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,930 | 4,930
Extracellular region 4,607 | 4,607
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,874 | 3,874
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,592 | 2,592
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,530 | 1,530
Cell projection 1,425 | 1,425
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,092 | 1,092
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,084 | 1,084
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 988 | 988
Nucleoli 950 | 950
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 815 | 815
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 656 | 656
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Lamin tail domain-containing protein 1 LMNTD1 Tdark Non-IDG 0.00000 1.11 56
Keratin, type II cytoskeletal 2 oral KRT76 Tdark Non-IDG -0.28255 1.97 104
Tubulin beta-3 chain TUBB3 Tclin Non-IDG -2.04546 78.8 485
RNA binding protein fox-1 homolog 3 RBFOX3 Tbio Non-IDG -3.20483 1368.4 194
Epithelial cell adhesion molecule EPCAM Tbio Non-IDG -3.16288 1470.6 1441
Alpha-methylacyl-CoA racemase AMACR Tbio Enzyme -2.45535 296.1 443
Myogenin MYOG Tbio Transcription Factor -2.95734 772.0 578
Myoblast determination protein 1 MYOD1 Tbio Transcription Factor -3.14842 1281.5 563
Zinc finger protein SNAI1 SNAI1 Tbio Transcription Factor -3.23809 1522.6 484
Serine/threonine-protein kinase tousled-like 2 TLK2 Tchem Kinase -0.91680 9.33 185