Development Level

Tbio 50 | 11,445
Tdark 10 | 6,588
Tchem 8 | 1,598

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

preweaning lethality, complete... 6 | 979
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
increased circulating HDL chol... 2 | 80
preweaning lethality, incomple... 2 | 499
abnormal bone structure 1 | 187
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal locomotor behavior 1 | 24
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
absent startle reflex 1 | 24
cataract 1 | 92
decreased brain size 1 | 4
decreased circulating chloride... 1 | 30
decreased circulating triglyce... 1 | 79
decreased cornea thickness 1 | 2
decreased lymphocyte cell numb... 1 | 83
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
decreased total retina thickne... 1 | 17
enlarged heart 1 | 210
hypoactivity 1 | 132
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating chloride... 1 | 41
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased thermal nociceptive ... 1 | 9
male infertility 1 | 123
prenatal lethality prior to he... 1 | 87
prolonged QRS complex duration 1 | 8
short tibia 1 | 97
small heart 1 | 10
small kidney 1 | 16
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 19
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

Carcinoma 49 | 11,493
ovarian cancer 29 | 8,520
glioblastoma 27 | 5,792
group 3 medulloblastoma 24 | 4,104
osteosarcoma 24 | 7,950
psoriasis 24 | 6,694
medulloblastoma, large-cell 21 | 6,241
malignant mesothelioma 20 | 3,232
lung cancer 19 | 4,740
Breast cancer 18 | 3,578
atypical teratoid / rhabdoid tumor 18 | 5,112
adult high grade glioma 17 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
ependymoma 16 | 4,679
primitive neuroectodermal tumor 16 | 3,035
invasive ductal carcinoma 14 | 2,951
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
non-small cell lung cancer 13 | 2,890
Cancer 12 | 2,499
Kidney cancer 12 | 2,613
ductal carcinoma in situ 11 | 1,745
adrenocortical carcinoma 10 | 1,428
breast carcinoma 10 | 1,638
lung adenocarcinoma 10 | 2,716
oligodendroglioma 10 | 2,850
astrocytic glioma 9 | 2,597
colon cancer 9 | 1,478
Astrocytoma, Pilocytic 8 | 3,081
Atopic dermatitis 8 | 952
Autosomal recessive predisposition 8 | 1,442
Endometriosis 8 | 540
pancreatic cancer 8 | 2,398
non primary Sjogren syndrome sicca 7 | 891
acute myeloid leukemia 5 | 783
cutaneous lupus erythematosus 5 | 1,057
interstitial cystitis 5 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
lung carcinoma 5 | 2,843
nasopharyngeal carcinoma 5 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
pancreatic ductal carcinoma 5 | 11
pediatric high grade glioma 5 | 1,064
pituitary cancer 5 | 1,972
Bipolar Disorder 4 | 666
Chemical and Drug Induced Liver Injury 4 | 195
Colorectal Neoplasms 4 | 243
Depressive disorder 4 | 409
Dull intelligence 4 | 645
Epilepsy 4 | 792
Intellectual disability 4 | 1,016
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Muscle hypotonia 4 | 571
Neurodegenerative Diseases 4 | 38
Neurodegenerative Disorders 4 | 79
Polycystic ovary syndrome 4 | 360
Poor school performance 4 | 645
Retinitis Pigmentosa 4 | 226
Schizophrenia 4 | 1,160
Seizures 4 | 596
active Crohn's disease 4 | 922
diabetes mellitus 4 | 1,728
group 4 medulloblastoma 4 | 1,855
progressive supranuclear palsy 4 | 676
sonic hedgehog group medulloblastoma 4 | 467
subependymal giant cell astrocytoma 4 | 2,287
ulcerative colitis 4 | 1,819
Anemia 3 | 365
Cerebellar Ataxia 3 | 304
Chronic kidney disease stage 5 3 | 31
Cognitive delay 3 | 608
Failure to gain weight 3 | 365
Fatigue 3 | 182
Global developmental delay 3 | 608
Hypogonadism 3 | 173
Mental and motor retardation 3 | 608
Pediatric failure to thrive 3 | 365
Prostatic Neoplasms 3 | 495
Proteinuria 3 | 144
Rheumatoid arthritis 3 | 1,191
aldosterone-producing adenoma 3 | 665
fibroadenoma 3 | 559
primary Sjogren syndrome 3 | 735
spina bifida 3 | 1,074
tuberculosis 3 | 2,010
tuberculosis and treatment for 6 months 3 | 409
Atherosclerosis 2 | 291
Byzanthine arch palate 2 | 194
Down syndrome 2 | 499
Leukemia 2 | 104
Mental Depression 2 | 333
Pick disease 2 | 1,894
Strabismus 2 | 270
Vascular disease 2 | 319
astrocytoma 2 | 1,146
dermatomyositis 2 | 966
esophageal adenocarcinoma 2 | 737
hepatocellular carcinoma 2 | 547
juvenile dermatomyositis 2 | 1,187

Tissue

Endocrine System 66 | 18,159
Male tissues 65 | 17,142
Female tissues 64 | 17,400
Skin and soft tissues 64 | 17,230
Blood and immune system 62 | 16,909
Digestive Tract 62 | 17,369
Nervous System 62 | 16,725
Urinary Tract 62 | 16,678
Liver and Pancreas 61 | 16,750
Respiratory system 60 | 16,393
Cardiovascular System 59 | 15,192

Target Family

Non-IDG 42 | 12,091
Enzyme 14 | 4,145
Kinase 6 | 634
Transcription Factor 4 | 1,400
Nuclear Receptor 1 | 48
oGPCR 1 | 421

Compartment GO Term

Intercellular bridge 68 | 68
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adenomatous polyposis coli protein 2 APC2 Tbio Non-IDG -1.50271 33.3 93
Fanconi-associated nuclease 1 FAN1 Tbio Enzyme -2.06970 115.9 85
Steroid receptor RNA activator 1 SRA1 Tbio Non-IDG -2.78991 595.4 160
Zinc finger protein 142 ZNF142 Tbio Transcription Factor 0.05 0.69 17
Hematopoietic progenitor cell antigen CD34 CD34 Tbio Non-IDG -4.14691 13698.4 1952
Centrosomal protein of 131 kDa CEP131 Tbio Non-IDG -1.78486 61.9 82
RelA-associated inhibitor PPP1R13L Tbio Non-IDG -1.76131 64.5 185
Cytosolic carboxypeptidase-like protein 5 AGBL5 Tbio Enzyme -0.97543 10.5 132
Inactive serine/threonine-protein kinase TEX14 TEX14 Tbio Kinase -0.97663 10.2 61
Acrosomal protein KIAA1210 KIAA1210 Tdark Non-IDG 0.38 0.70 9