Development Level

Tbio 30 | 11,445
Tchem 5 | 1,598
Tclin 3 | 613
Tdark 2 | 6,588

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

abnormal embryo size 2 | 220
decreased cardiac muscle contr... 2 | 11
dilated heart left ventricle 2 | 11
increased heart weight 2 | 62
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal cornea morphology 1 | 31
abnormal head morphology 1 | 10
abnormal pericardium morpholog... 1 | 26
abnormal startle reflex 1 | 15
corneal opacity 1 | 32
corneal vascularization 1 | 6
decreased bone mineral content 1 | 151
decreased coping response 1 | 8
decreased fasted circulating g... 1 | 65
decreased neutrophil cell numb... 1 | 42
edema 1 | 59
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
increased blood urea nitrogen ... 1 | 48
increased bone mineral density 1 | 72
increased circulating triglyce... 1 | 42
increased heart left ventricle... 1 | 4
increased hemoglobin content 1 | 45
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
mammalian phenotype 1 | 17
narrow eye opening 1 | 12
prenatal lethality 1 | 28
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
thick ventricular wall 1 | 7

Disease

Carcinoma 30 | 11,493
ovarian cancer 27 | 8,520
atypical teratoid / rhabdoid tumor 23 | 5,112
glioblastoma 21 | 5,792
lung cancer 21 | 4,740
ependymoma 20 | 4,679
medulloblastoma, large-cell 20 | 6,241
psoriasis 20 | 6,694
intraductal papillary-mucinous neoplasm (IPMN) 19 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,989
Breast cancer 17 | 3,578
primitive neuroectodermal tumor 17 | 3,035
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
non-small cell lung cancer 16 | 2,890
osteosarcoma 16 | 7,950
Astrocytoma, Pilocytic 15 | 3,081
group 3 medulloblastoma 15 | 4,104
Kidney cancer 14 | 2,613
adult high grade glioma 14 | 3,801
lung adenocarcinoma 13 | 2,716
malignant mesothelioma 13 | 3,232
Cardiomyopathy 12 | 116
interstitial cystitis 12 | 2,312
lung carcinoma 12 | 2,843
oligodendroglioma 12 | 2,850
astrocytic glioma 11 | 2,597
group 4 medulloblastoma 11 | 1,855
pancreatic cancer 11 | 2,398
pituitary cancer 11 | 1,972
Cancer 10 | 2,499
Dilated cardiomyopathy 10 | 56
colon cancer 10 | 1,478
ductal carcinoma in situ 10 | 1,745
invasive ductal carcinoma 10 | 2,951
adrenocortical carcinoma 9 | 1,428
Arrhythmogenic right ventricular cardiomyopathy 8 | 30
Autosomal recessive predisposition 8 | 1,442
Pick disease 8 | 1,894
cystic fibrosis 8 | 1,696
Heart disease 7 | 306
Liver cancer 7 | 604
Melanoma 7 | 711
Schizophrenia 7 | 1,160
Sudden Cardiac Death 7 | 29
acute quadriplegic myopathy 7 | 1,158
breast carcinoma 7 | 1,638
subependymal giant cell astrocytoma 7 | 2,287
Atrial Fibrillation 6 | 124
Cardiac Arrhythmia 6 | 103
Cardiomyopathy, Dilated 6 | 83
Endometrial cancer 6 | 311
Skin cancer 6 | 469
dermatomyositis 6 | 966
diabetes mellitus 6 | 1,728
spina bifida 6 | 1,074
tuberculosis 6 | 2,010
ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder) 5 | 21
Brugada syndrome 5 | 29
Cardiomyopathy, right ventricular 5 | 7
Familial atrial fibrillation 5 | 23
Hypertension 5 | 396
Palpitations 5 | 18
Syncope 5 | 22
Tachycardia, Ventricular 5 | 22
gastric carcinoma 5 | 807
ulcerative colitis 5 | 1,819
Alopecia 4 | 115
Autistic Disorder 4 | 364
Bipolar Disorder 4 | 666
Breast Neoplasms 4 | 445
Congestive heart failure 4 | 113
Down syndrome 4 | 499
Dull intelligence 4 | 645
Familial isolated dilated cardiomyopathy 4 | 41
Immune system cancer 4 | 140
Intellectual disability 4 | 1,016
LEFT VENTRICULAR NONCOMPACTION 10 4 | 40
LEFT VENTRICULAR NONCOMPACTION 8 4 | 40
Long QT syndrome 4 | 39
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Muscle hypotonia 4 | 571
Palmoplantar keratosis 4 | 74
Pemphigus 4 | 23
Poor school performance 4 | 645
Status Epilepticus 4 | 98
Ventricular arrhythmia 4 | 27
acute myeloid leukemia 4 | 783
juvenile dermatomyositis 4 | 1,187
non primary Sjogren syndrome sicca 4 | 891
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Atopic dermatitis 3 | 952
Epilepsy 3 | 792
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
esophageal adenocarcinoma 3 | 737
mucosa-associated lymphoid tissue lymphoma 3 | 484
nasopharyngeal carcinoma 3 | 1,058
primary pancreatic ductal adenocarcinoma 3 | 1,109
urothelial carcinoma 3 | 318

Tissue

Blood and immune system 39 | 16,909
Cardiovascular System 39 | 15,192
Digestive Tract 39 | 17,369
Endocrine System 39 | 18,159
Female tissues 39 | 17,400
Liver and Pancreas 39 | 16,750
Male tissues 39 | 17,142
Nervous System 39 | 16,725
Skin and soft tissues 39 | 17,230
Urinary Tract 39 | 16,678
Respiratory system 37 | 16,393

Target Family

Non-IDG 27 | 12,091
Ion Channel 5 | 344
Enzyme 3 | 4,145
Kinase 3 | 634
Transporter 2 | 473

Compartment GO Term

Intercalated disc 40 | 40
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Plakophilin-2 PKP2 Tbio Non-IDG -2.10355 135.3 243
Desmin DES Tbio Non-IDG -1.56068 36.6 991
Ankyrin-2 ANK2 Tbio Non-IDG -2.08421 120.5 236
Nebulin-related-anchoring protein NRAP Tbio Non-IDG -0.50644 3.42 54
Xin actin-binding repeat-containing protein 1 XIRP1 Tbio Non-IDG -2.15574 137.9 66
Sodium channel subunit beta-4 SCN4B Tbio Ion Channel -1.42029 24.1 85
Cadherin-17 CDH17 Tbio Non-IDG -3.38219 2005.5 312
Myocardial zonula adherens protein POLR2M Tbio Non-IDG -1.87592 70.6 20
Desmoplakin DSP Tbio Non-IDG -2.95735 853.9 198
Gap junction alpha-5 protein GJA5 Tbio Non-IDG -2.59423 377.5 194