Development Level

Tbio 79 | 11,445
Tchem 33 | 1,598
Tclin 21 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 10 | 979
preweaning lethality, incomple... 5 | 499
abnormal behavior 4 | 298
embryonic lethality prior to o... 4 | 239
abnormal embryo size 3 | 220
embryonic lethality prior to t... 3 | 278
abnormal behavioral response t... 2 | 66
abnormal bone structure 2 | 187
abnormal retina morphology 2 | 71
decreased body weight 2 | 161
decreased circulating serum al... 2 | 82
decreased leukocyte cell numbe... 2 | 73
hemorrhage 2 | 23
increased circulating triglyce... 2 | 42
increased leukocyte cell numbe... 2 | 47
increased neutrophil cell numb... 2 | 46
increased spleen weight 2 | 10
increased total body fat amoun... 2 | 134
short tibia 2 | 97
abnormal anxiety-related respo... 1 | 1
abnormal bone mineralization 1 | 38
abnormal cranium morphology 1 | 36
abnormal digit morphology 1 | 10
abnormal eye anterior chamber ... 1 | 9
abnormal femur morphology 1 | 14
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal sleep behavior 1 | 70
abnormal social-conspecific in... 1 | 3
cataract 1 | 92
decreased IgG3 level 1 | 1
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating free fat... 1 | 31
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mature B cell number 1 | 7
decreased neutrophil cell numb... 1 | 42
decreased spleen weight 1 | 10
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
edema 1 | 59
enlarged heart 1 | 210
enlarged kidney 1 | 14
enlarged uterus 1 | 11
hydrometra 1 | 53
hyperactivity 1 | 148
impaired righting response 1 | 26
increased IgG1 level 1 | 1
increased IgM level 1 | 1
increased T cell number 1 | 6
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased exploration in new e... 1 | 8
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
limb grasping 1 | 41
mydriasis 1 | 6
small superior vagus ganglion 1 | 74
tremors 1 | 39
unresponsive to tactile stimul... 1 | 8

Disease

Cancer 105 | 2,499
Carcinoma 100 | 11,493
glioblastoma 81 | 5,792
osteosarcoma 78 | 7,950
ovarian cancer 75 | 8,520
psoriasis 72 | 6,694
lung cancer 64 | 4,740
lung carcinoma 62 | 2,843
interstitial cystitis 61 | 2,312
invasive ductal carcinoma 58 | 2,951
non-small cell lung cancer 58 | 2,890
diabetes mellitus 53 | 1,728
Astrocytoma, Pilocytic 52 | 3,081
malignant mesothelioma 52 | 3,232
adult high grade glioma 49 | 3,801
ependymoma 49 | 4,679
pancreatic cancer 49 | 2,398
atypical teratoid / rhabdoid tumor 48 | 5,112
tuberculosis 48 | 2,010
Breast cancer 47 | 3,578
ulcerative colitis 46 | 1,819
lung adenocarcinoma 45 | 2,716
intraductal papillary-mucinous carcinoma (IPMC) 43 | 2,989
medulloblastoma, large-cell 43 | 6,241
Kidney disease 41 | 430
Hypersensitivity reaction type II disease 40 | 253
intraductal papillary-mucinous adenoma (IPMA) 40 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 40 | 3,291
cystic fibrosis 38 | 1,696
Arthritis 35 | 290
Kidney cancer 34 | 2,613
Liver Cirrhosis, Experimental 33 | 769
Multiple Sclerosis 33 | 540
Asthma 32 | 385
Heart disease 32 | 306
cutaneous lupus erythematosus 32 | 1,057
primary pancreatic ductal adenocarcinoma 32 | 1,109
Atherosclerosis 30 | 291
Lung disease 30 | 142
ductal carcinoma in situ 29 | 1,745
subependymal giant cell astrocytoma 29 | 2,287
Coronary artery disease 28 | 268
Schizophrenia 28 | 1,160
Cerebrovascular disease 27 | 238
Inflammatory bowel disease 27 | 151
Anemia 26 | 365
Autosomal recessive predisposition 26 | 1,442
Neoplasm Invasiveness 26 | 161
Rheumatoid arthritis 26 | 1,191
oligodendroglioma 26 | 2,850
Thrombocytopenia 25 | 197
Hypertension 24 | 396
Dermatitis 23 | 157
Liver disease 23 | 237
Vascular disease 23 | 319
pituitary cancer 23 | 1,972
Breast Neoplasms 22 | 445
Mammary Neoplasms 22 | 425
Neoplasm Metastasis 22 | 168
breast carcinoma 22 | 1,638
group 3 medulloblastoma 22 | 4,104
periodontitis 22 | 293
Obesity 21 | 678
Prostatic Neoplasms 21 | 495
pancreatic ductal adenocarcinoma liver metastasis 21 | 1,962
colon cancer 20 | 1,478
primary Sjogren syndrome 20 | 735
Pulmonary Fibrosis 19 | 106
nasopharyngeal carcinoma 19 | 1,058
primitive neuroectodermal tumor 19 | 3,035
Duchenne muscular dystrophy 18 | 601
Endometriosis 18 | 540
astrocytic glioma 18 | 2,597
gastric carcinoma 18 | 807
Allergic hypersensitivity disease 17 | 126
Human immunodeficiency virus infectious disease 17 | 138
Hypertensive disease 17 | 292
Malaria 17 | 160
Stomach Neoplasms 17 | 300
adrenocortical carcinoma 17 | 1,428
dermatomyositis 17 | 966
esophageal adenocarcinoma 17 | 737
juvenile dermatomyositis 17 | 1,187
mucosa-associated lymphoid tissue lymphoma 17 | 484
Alzheimer's disease 16 | 658
Osteoporosis 16 | 363
autosomal dominant Emery-Dreifuss muscular dystrophy 16 | 510
sarcoidosis 16 | 370
Bipolar Disorder 15 | 666
Hypereosinophilic syndrome 15 | 71
Influenza 15 | 142
Melanoma 15 | 711
Pneumonia 15 | 174
astrocytoma 15 | 1,146
group 4 medulloblastoma 15 | 1,855
Arthritis, Rheumatoid 14 | 174
Atopic dermatitis 14 | 952
Multiple myeloma 14 | 1,332
Peripheral vascular disease 14 | 87
Waldenstrons macroglobulinemia 14 | 765

Tissue

Female tissues 133 | 17,400
Digestive Tract 132 | 17,369
Endocrine System 132 | 18,159
Liver and Pancreas 132 | 16,750
Skin and soft tissues 132 | 17,230
Blood and immune system 131 | 16,909
Male tissues 131 | 17,142
Respiratory system 131 | 16,393
Urinary Tract 130 | 16,678
Nervous System 128 | 16,725
Cardiovascular System 122 | 15,192

Target Family

Non-IDG 102 | 12,091
Enzyme 16 | 4,145
Kinase 11 | 634
GPCR 3 | 408
Transcription Factor 2 | 1,400

Compartment GO Term

Integrin complex 134 | 134
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Integrin alpha-11 ITGA11 Tbio Non-IDG -1.13736 14.3 76
Tubulin beta-4A chain TUBB4A Tclin Non-IDG -2.98371 896.1 90
Disintegrin and metalloproteinase domain-containing protein 15 ADAM15 Tbio Enzyme -1.87408 84.1 301
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 CD38 Tclin Enzyme -3.44680 2663.1 1493
Hematopoietic progenitor cell antigen CD34 CD34 Tbio Non-IDG -4.14691 13698.4 1952
Cadherin-17 CDH17 Tbio Non-IDG -3.38219 2005.5 312
Collagen alpha-1(XVII) chain COL17A1 Tbio Non-IDG -2.75473 576.3 123
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 PLCG2 Tchem Enzyme -2.41628 245.1 733
Integrin alpha-7 ITGA7 Tbio Non-IDG -1.63563 42.4 193
C-C motif chemokine 2 CCL2 Tchem Non-IDG -3.84820 7088.3 1260