Development Level

Tbio 14 | 11,445
Tdark 1 | 6,588

IMPC Phenotype

decreased circulating HDL chol... 2 | 68
decreased circulating choleste... 2 | 93
decreased total body fat amoun... 2 | 207
abnormal coat appearance 1 | 31
abnormal cornea morphology 1 | 31
abnormal eye morphology 1 | 68
abnormal eye size 1 | 7
abnormal lens morphology 1 | 81
abnormal sleep behavior 1 | 70
abnormal tail morphology 1 | 25
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased body weight 1 | 161
decreased caudal vertebrae num... 1 | 53
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased coping response 1 | 8
decreased heart rate variabili... 1 | 13
decreased vertical activity 1 | 208
increased bone mineral density 1 | 72
increased circulating bilirubi... 1 | 16
increased circulating fructosa... 1 | 13
increased heart rate 1 | 23
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
male infertility 1 | 123
preweaning lethality, complete... 1 | 979
shortened RR interval 1 | 17

Disease

Zellweger syndrome 10 | 37
Epilepsy 9 | 792
Peroxisomal disease 9 | 22
Addison Disease 8 | 18
Adrenal cortical hypofunction 8 | 23
Cataract 8 | 297
Infantile Refsum disease 8 | 23
Optic Atrophy 8 | 242
Seizures 8 | 596
psoriasis 8 | 6,694
Abnormal behavior 7 | 52
Abnormal skeletal development 7 | 60
Abnormality of metabolism/homeostasis 7 | 134
Abnormality of retinal pigmentation 7 | 111
Abnormality of the liver 7 | 21
Abnormality of the palate 7 | 17
Adrenoleukodystrophy, Neonatal 7 | 13
Anteverted nostril 7 | 191
Bilateral single transverse palmar creases 7 | 34
Blepharoptosis 7 | 231
Broad flat nasal bridge 7 | 236
Byzanthine arch palate 7 | 194
Clouding of corneal stroma 7 | 50
Concave bridge of nose 7 | 195
Congenital Epicanthus 7 | 177
Corneal Opacity 7 | 53
Death in early childhood 7 | 82
Death in infancy 7 | 82
Decreased to absent deep tendon reflexes 7 | 42
Depressed nasal bridge 7 | 195
Depressed nasal root/bridge 7 | 195
Developmental regression 7 | 95
Difficulties with night vision 7 | 87
Electroencephalogram abnormal 7 | 101
Elevated levels of phytanic acid 7 | 15
Embryotoxon 7 | 28
Failure to gain weight 7 | 365
Flat back of the head 7 | 26
Flat face 7 | 52
Flat occiput 7 | 26
Global developmental delay, severe 7 | 47
Hepatomegaly 7 | 285
High forehead 7 | 102
Hydronephrosis 7 | 89
Hyperreflexia 7 | 209
Hypertrophy of clitoris 7 | 40
Hypotonia, severe 7 | 33
Icterus 7 | 82
Impaired cognition 7 | 96
Increased head circumference 7 | 147
Increased size of skull 7 | 147
Infantile Refsum Disease (disorder) 7 | 13
Liver Failure 7 | 73
Liver diseases 7 | 87
Long narrow head 7 | 75
Loss of developmental milestones 7 | 95
Low Vision 7 | 174
Malabsorption 7 | 82
Malformations of Cortical Development, Group II 7 | 31
Malformed pinnae 7 | 37
Mental deterioration in childhood 7 | 95
Mental impairment 7 | 95
Movement Disorders 7 | 55
Muscle Spasticity 7 | 195
Muscle weakness, progressive 7 | 22
Narrow head shape 7 | 75
Narrow skull shape 7 | 75
Nasal bridge wide 7 | 236
Neurodevelopmental regression 7 | 95
Night Blindness 7 | 101
Osteochondrodysplasias 7 | 72
Pediatric failure to thrive 7 | 365
Penile hypospadias 7 | 106
Polymicrogyria 7 | 48
Posterior embryotoxon 7 | 28
Premature Birth 7 | 77
Premature birth of newborn 7 | 67
Profound global developmental delay 7 | 17
Psychomotor regression 7 | 95
Psychomotor regression beginning in infancy 7 | 95
Psychomotor regression in infants 7 | 95
Psychomotor regression, progressive 7 | 95
Psychomotor retardation, profound 7 | 17
Pyloric Stenosis 7 | 47
Respiratory Insufficiency 7 | 132
Respiratory function loss 7 | 121
Retinal pigment epithelial abnormality 7 | 111
Sensorineural Hearing Loss (disorder) 7 | 284
Severe psychomotor retardation 7 | 47
Stippled epiphyses 7 | 28
Strabismus 7 | 270
Tall forehead 7 | 102
Turridolichocephaly 7 | 75
Underdeveloped brows 7 | 38
Underdeveloped supraorbital ridges 7 | 38
Upward slant of palpebral fissure 7 | 75
Very long chain fatty acid accumulation 7 | 13
Visual Impairment 7 | 174
Visual field constriction 7 | 36
Wide anterior fontanel 7 | 44

Tissue

Blood and immune system 15 | 16,909
Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Liver and Pancreas 15 | 16,750
Male tissues 15 | 17,142
Nervous System 15 | 16,725
Respiratory system 15 | 16,393
Skin and soft tissues 15 | 17,230
Urinary Tract 15 | 16,678
Cardiovascular System 14 | 15,192

Target Family

Non-IDG 10 | 12,091
Transporter 3 | 473
Enzyme 2 | 4,145

Compartment GO Term

Integral component of peroxiso... 15 | 15
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Peroxisomal membrane protein PEX16 PEX16 Tbio Non-IDG -1.43594 27.8 78
Fatty acyl-CoA reductase 1 FAR1 Tbio Enzyme -1.65427 43.8 27
Peroxisome biogenesis factor 2 PEX2 Tbio Non-IDG -1.76849 57.3 170
Peroxisomal membrane protein PMP34 SLC25A17 Tbio Transporter -2.14978 108.6 79
Peroxisomal biogenesis factor 3 PEX3 Tbio Non-IDG -1.79362 72.7 79
Peroxisomal membrane protein 11B PEX11B Tbio Non-IDG -1.00971 10.5 80
Very long-chain acyl-CoA synthetase SLC27A2 Tbio Transporter -1.73251 54.7 121
Peroxisomal membrane protein 2 PXMP2 Tdark Non-IDG -0.43669 3.82 115
Mitochondrial fission 1 protein FIS1 Tbio Non-IDG -2.19572 143.4 224
Peroxisomal membrane protein 11A PEX11A Tbio Non-IDG -1.72726 55.8 122