Development Level

Tbio 113 | 11,651
Tdark 26 | 6,593
Tchem 9 | 1,388
Tclin 2 | 612

IMPC Phenotype

preweaning lethality, complete... 14 | 979
embryonic lethality prior to t... 5 | 278
decreased total body fat amoun... 4 | 207
embryonic lethality prior to o... 4 | 239
increased total body fat amoun... 4 | 134
cataract 3 | 92
decreased body weight 3 | 161
decreased circulating alanine ... 3 | 47
decreased circulating choleste... 3 | 93
decreased heart weight 3 | 27
decreased vertical activity 3 | 208
increased lean body mass 3 | 172
abnormal behavior 2 | 298
abnormal coat appearance 2 | 31
abnormal embryo size 2 | 220
abnormal eye morphology 2 | 68
abnormal sleep behavior 2 | 70
decreased bone mineral content 2 | 151
decreased circulating HDL chol... 2 | 68
decreased circulating iron lev... 2 | 32
decreased grip strength 2 | 116
decreased lean body mass 2 | 135
decreased mean platelet volume 2 | 25
enlarged heart 2 | 210
impaired righting response 2 | 26
increased circulating alkaline... 2 | 122
increased heart weight 2 | 62
increased startle reflex 2 | 112
male infertility 2 | 123
preweaning lethality, incomple... 2 | 499
small superior vagus ganglion 2 | 74
abnormal behavioral response t... 1 | 66
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal epididymis morphology 1 | 42
abnormal forebrain development 1 | 20
abnormal gait 1 | 69
abnormal hindbrain development 1 | 16
abnormal lens morphology 1 | 81
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal tail morphology 1 | 25
abnormal thymus morphology 1 | 7
abnormal vibrissa morphology 1 | 25
absent startle reflex 1 | 24
absent vibrissae 1 | 12
cardiovascular system phenotyp... 1 | 36
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating LDL chol... 1 | 38
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating chloride... 1 | 30
decreased circulating creatine... 1 | 4
decreased circulating fructosa... 1 | 30
decreased circulating magnesiu... 1 | 13
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased food intake 1 | 13
decreased heart rate variabili... 1 | 13
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged epididymis 1 | 31
enlarged spleen 1 | 41
hydrometra 1 | 53
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating amylase ... 1 | 25
increased circulating bilirubi... 1 | 16
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating fructosa... 1 | 13
increased circulating glycerol... 1 | 9
increased circulating magnesiu... 1 | 10
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased spleen weight 1 | 10
long tibia 1 | 25
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
shortened RR interval 1 | 17
small adrenal glands 1 | 16
small seminal vesicle 1 | 10
small thymus 1 | 16
tremors 1 | 39

Disease

ovarian cancer 80 | 8,520
osteosarcoma 64 | 7,950
Carcinoma 63 | 11,493
medulloblastoma, large-cell 57 | 6,241
glioblastoma 51 | 5,792
atypical teratoid / rhabdoid tumor 49 | 5,112
psoriasis 47 | 6,694
ependymoma 36 | 4,679
lung cancer 36 | 4,740
adult high grade glioma 30 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 28 | 3,291
Breast cancer 26 | 3,578
astrocytic glioma 26 | 2,597
group 3 medulloblastoma 25 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,955
pancreatic ductal adenocarcinoma liver metastasis 25 | 1,962
Astrocytoma, Pilocytic 23 | 3,081
Autosomal recessive predisposition 23 | 1,442
oligodendroglioma 23 | 2,850
Pick disease 21 | 1,894
intraductal papillary-mucinous carcinoma (IPMC) 21 | 2,989
primitive neuroectodermal tumor 21 | 3,035
Epilepsy 19 | 792
malignant mesothelioma 18 | 3,232
group 4 medulloblastoma 17 | 1,855
non-small cell lung cancer 17 | 2,890
subependymal giant cell astrocytoma 16 | 2,287
interstitial cystitis 15 | 2,312
lung carcinoma 15 | 2,843
ulcerative colitis 15 | 1,819
Cognitive delay 14 | 608
Global developmental delay 14 | 608
Mental and motor retardation 14 | 608
Muscle hypotonia 14 | 571
Optic Atrophy 14 | 242
invasive ductal carcinoma 14 | 2,951
Cataract 13 | 297
Cerebellar Ataxia 13 | 304
Multiple myeloma 13 | 1,332
pituitary cancer 13 | 1,972
Hepatomegaly 12 | 285
Seizures 12 | 596
lung adenocarcinoma 12 | 2,716
pancreatic cancer 12 | 2,398
Blepharoptosis 11 | 231
Rheumatoid arthritis 11 | 1,191
Small head 11 | 374
tuberculosis 11 | 2,010
Failure to gain weight 10 | 365
Feeding difficulties in infancy 10 | 175
Icterus 10 | 82
Lens Opacities 10 | 231
Muscle Spasticity 10 | 195
Neurodegenerative disease 10 | 414
Nystagmus 10 | 317
Pediatric failure to thrive 10 | 365
Zellweger syndrome 10 | 37
progressive supranuclear palsy 10 | 676
Big calvaria 9 | 147
Byzanthine arch palate 9 | 194
Concave bridge of nose 9 | 195
Depressed nasal bridge 9 | 195
Depressed nasal root/bridge 9 | 195
Flat back of the head 9 | 26
Flat occiput 9 | 26
High forehead 9 | 102
Hyperreflexia 9 | 209
Hypotonia, severe 9 | 33
Increased head circumference 9 | 147
Increased size of cranium 9 | 147
Increased size of skull 9 | 147
Liver Failure 9 | 73
Peroxisomal disease 9 | 22
Respiratory Insufficiency 9 | 132
Respiratory function loss 9 | 121
Short stature 9 | 531
Strabismus 9 | 270
Tall forehead 9 | 102
dermatomyositis 9 | 966
Abnormal behavior 8 | 52
Addison Disease 8 | 18
Anteverted nostril 8 | 191
Broad flat nasal bridge 8 | 236
Clouding of corneal stroma 8 | 50
Corneal Opacity 8 | 53
Decreased to absent deep tendon reflexes 8 | 42
Electroencephalogram abnormal 8 | 101
Hypoplastic mandible condyle 8 | 275
Impaired cognition 8 | 96
Infantile Refsum disease 8 | 23
Low Vision 8 | 174
Mental impairment 8 | 95
Movement Disorders 8 | 55
Nasal bridge wide 8 | 236
Polymicrogyria 8 | 48
Premature Birth 8 | 77
Premature birth of newborn 8 | 67
Sensorineural Hearing Loss (disorder) 8 | 284
Visual Impairment 8 | 174
Waldenstrons macroglobulinemia 8 | 765

Tissue

Endocrine System 149 | 18,159
Digestive Tract 148 | 17,369
Female tissues 148 | 17,400
Male tissues 148 | 17,142
Liver and Pancreas 147 | 16,750
Nervous System 147 | 16,725
Skin and soft tissues 147 | 17,230
Respiratory system 146 | 16,393
Urinary Tract 146 | 16,678
Blood and immune system 145 | 16,909
Cardiovascular System 142 | 15,192

Target Family

Non-IDG 74 | 12,091
Enzyme 47 | 4,145
Transporter 16 | 473
Ion Channel 10 | 344
Kinase 2 | 634
Epigenetic 1 | 242

Compartment GO Term

Integral component of organell... 150 | 150
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
UbiA prenyltransferase domain-containing protein 1 UBIAD1 Tbio Enzyme -1.59893 42.5 50
Transmembrane protein 11, mitochondrial TMEM11 Tdark Non-IDG -2.44072 252.5 35
Transmembrane protein 70, mitochondrial TMEM70 Tbio Non-IDG -1.36229 24.6 93
Mitochondrial pyruvate carrier 1 MPC1 Tbio Non-IDG -1.77095 56.4 96
Immediate early response 3-interacting protein 1 IER3IP1 Tbio Non-IDG -2.47342 292.3 18
Protein YIF1B YIF1B Tbio Non-IDG -0.87118 7.59 87
FUN14 domain-containing protein 2 FUNDC2 Tdark Non-IDG -0.67611 3.86 78
Carnitine O-palmitoyltransferase 1, liver isoform CPT1A Tchem Enzyme -2.38489 225.0 306
Serine/threonine-protein kinase PINK1, mitochondrial PINK1 Tbio Kinase -2.81574 706.5 546
Beta-1,4-glucuronyltransferase 1 B4GAT1 Tbio Enzyme -1.18067 14.2 104