Development Level

Tbio 16 | 11,651
Tdark 3 | 6,593
Tchem 2 | 1,388

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal adrenal gland morphol... 1 | 1
abnormal behavior 1 | 298
abnormal epididymis morphology 1 | 42
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal thymus morphology 1 | 7
abnormal vibrissa morphology 1 | 25
absent startle reflex 1 | 24
cataract 1 | 92
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 46
decreased circulating iron lev... 1 | 32
decreased circulating magnesiu... 1 | 13
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased mean platelet volume 1 | 25
decreased vertical activity 1 | 208
enlarged epididymis 1 | 31
enlarged heart 1 | 210
hyperactivity 1 | 148
increased circulating bilirubi... 1 | 16
increased circulating glycerol... 1 | 9
increased heart weight 1 | 62
increased total body fat amoun... 1 | 134
small adrenal glands 1 | 16
small superior vagus ganglion 1 | 74
small thymus 1 | 16

Disease

ovarian cancer 12 | 8,520
medulloblastoma, large-cell 8 | 6,241
atypical teratoid / rhabdoid tumor 7 | 5,112
lung cancer 7 | 4,740
osteosarcoma 7 | 7,950
glioblastoma 6 | 5,792
psoriasis 6 | 6,694
Breast cancer 5 | 3,578
Carcinoma 5 | 11,493
Multiple myeloma 4 | 1,332
adult high grade glioma 4 | 3,801
Astrocytoma, Pilocytic 3 | 3,081
Neurodegenerative disease 3 | 414
dermatomyositis 3 | 966
diabetes mellitus 3 | 1,728
ependymoma 3 | 4,679
group 3 medulloblastoma 3 | 4,104
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
Alzheimer's disease 2 | 658
Autosomal recessive predisposition 2 | 1,442
Cancer 2 | 2,499
Ceroid lipofuscinosis, neuronal 1, infantile 2 | 10
Feeding difficulties in infancy 2 | 175
Major Depressive Disorder 2 | 301
Muscle hypotonia 2 | 571
Nerve Degeneration 2 | 121
Neurogenic Muscular Atrophy 2 | 139
Neurogenic muscle atrophy, especially in the lower limbs 2 | 139
Neuropathy 2 | 261
Obesity 2 | 678
Optic Atrophy 2 | 242
Parkinson's disease 2 | 392
Pick disease 2 | 1,894
Polycystic ovary syndrome 2 | 360
Rheumatoid arthritis 2 | 1,191
Skeletal muscle atrophy 2 | 139
Unipolar Depression 2 | 250
acute quadriplegic myopathy 2 | 1,158
astrocytic glioma 2 | 2,597
colon cancer 2 | 1,478
esophageal adenocarcinoma 2 | 737
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
juvenile dermatomyositis 2 | 1,187
malignant mesothelioma 2 | 3,232
medulloblastoma 2 | 720
muscle degeneration 2 | 139
non-small cell lung cancer 2 | 2,890
pituitary cancer 2 | 1,972
primary pancreatic ductal adenocarcinoma 2 | 1,109
primitive neuroectodermal tumor 2 | 3,035
ulcerative colitis 2 | 1,819
Abnormal hair quantity 1 | 16
Abnormality of the endocrine system 1 | 9
Atrophy of testis 1 | 14
CNS hypomyelination 1 | 17
Cafe au lait spots, multiple 1 | 17
Cardiac arrest 1 | 36
Charcot-Marie-Tooth disease axonal type 2K 1 | 2
Charcot-Marie-Tooth disease, Type 2K 1 | 2
Cholelithiasis 1 | 33
Claw hand 1 | 26
Coloboma 1 | 51
Coloboma of eyelid 1 | 15
Coloboma of lens 1 | 4
Coloboma of macula 1 | 4
Congenital bile acid synthesis defect 1 | 15
Congenital coloboma of iris 1 | 4
Decreased motor NCV 1 | 22
Depletion of large myelinated fibers 1 | 7
Endocrine System Diseases 1 | 11
Foot dorsiflexor weakness 1 | 27
Foot-drop 1 | 27
Gait, Drop Foot 1 | 24
Hemiplegia and hemiparesis 1 | 38
Hereditary macular coloboma 1 | 5
Hyperkalemia 1 | 17
Hyperkalemic periodic paralysis 1 | 9
Hyperpigmented macules 1 | 42
Hypomyelination 1 | 17
Kidney Failure, Chronic 1 | 46
Kleptomania 1 | 2
Liver Neoplasms, Experimental 1 | 59
Mask-like facies 1 | 25
Microphthalmia 1 | 76
Myotonic dystrophy type 1 1 | 17
Myotonic dystrophy type 2 1 | 8
Neonatal onset 1 | 21
Nonorganic psychosis 1 | 84
Peripheral axonal degeneration 1 | 4
Peripheral hypomyelination 1 | 7
Photosensitivity of skin 1 | 51
Polyneuropathy 1 | 64
Progressive mental retardation 1 | 37
Rapidly progressive 1 | 27
Rapidly progressive disorder 1 | 27
Spinocerebellar ataxia type 12 1 | 5
Steatohepatitis 1 | 44
Trichotillomania 1 | 7

Tissue

Blood and immune system 21 | 16,909
Cardiovascular System 21 | 15,192
Digestive Tract 21 | 17,369
Endocrine System 21 | 18,159
Female tissues 21 | 17,400
Liver and Pancreas 21 | 16,750
Male tissues 21 | 17,142
Nervous System 21 | 16,725
Respiratory system 21 | 16,393
Skin and soft tissues 21 | 17,230
Urinary Tract 21 | 16,678

Target Family

Non-IDG 13 | 12,091
Enzyme 4 | 4,145
Kinase 2 | 634
Transporter 2 | 473

Compartment GO Term

Integral component of mitochon... 21 | 21
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
FUN14 domain-containing protein 2 FUNDC2 Tdark Non-IDG -0.67611 3.86 78
Carnitine O-palmitoyltransferase 1, liver isoform CPT1A Tchem Enzyme -2.38489 225.0 306
Serine/threonine-protein kinase PINK1, mitochondrial PINK1 Tbio Kinase -2.81574 706.5 546
Mitofusin-1 MFN1 Tbio Non-IDG -2.10909 104.1 0
Mitochondrial fission 1 protein FIS1 Tbio Non-IDG -2.19572 143.4 224
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 BNIP3 Tbio Non-IDG -2.51675 340.9 331
Mitochondrial Rho GTPase 2 RHOT2 Tbio Enzyme -1.36479 21.2 119
Mitochondrial Rho GTPase 1 RHOT1 Tbio Enzyme -1.52813 33.9 192
Mitochondrial import receptor subunit TOM20 homolog TOMM20 Tbio Non-IDG -2.20240 151.7 140
Mitochondrial ubiquitin ligase activator of NFKB 1 MUL1 Tbio Enzyme -2.41710 245.8 150