Development Level

Tbio 29 | 11,445
Tdark 12 | 6,588
Tchem 4 | 1,598

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal embryo size 2 | 220
decreased circulating alanine ... 2 | 47
decreased total body fat amoun... 2 | 207
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
increased lean body mass 2 | 172
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal forebrain development 1 | 20
abnormal heart morphology 1 | 162
abnormal hindbrain development 1 | 16
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
decreased bone mineral content 1 | 151
decreased circulating choleste... 1 | 93
decreased grip strength 1 | 116
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
increased body length 1 | 32
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating magnesiu... 1 | 10
increased grip strength 1 | 41
increased mean platelet volume 1 | 45
increased startle reflex 1 | 112
male infertility 1 | 123
thrombocytopenia 1 | 56
tremors 1 | 39

Disease

ovarian cancer 30 | 8,520
Carcinoma 25 | 11,493
medulloblastoma, large-cell 24 | 6,241
glioblastoma 22 | 5,792
atypical teratoid / rhabdoid tumor 19 | 5,112
osteosarcoma 19 | 7,950
ependymoma 11 | 4,679
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
psoriasis 11 | 6,694
Astrocytoma, Pilocytic 9 | 3,081
Breast cancer 9 | 3,578
lung adenocarcinoma 8 | 2,716
malignant mesothelioma 8 | 3,232
Pick disease 7 | 1,894
Rheumatoid arthritis 7 | 1,191
adult high grade glioma 7 | 3,801
group 3 medulloblastoma 7 | 4,104
oligodendroglioma 7 | 2,850
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
lung cancer 6 | 4,740
primitive neuroectodermal tumor 6 | 3,035
Kidney cancer 5 | 2,613
active Crohn's disease 5 | 922
astrocytoma 5 | 1,146
group 4 medulloblastoma 5 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
lung carcinoma 5 | 2,843
non-small cell lung cancer 5 | 2,890
Autosomal recessive predisposition 4 | 1,442
Cognitive delay 4 | 608
Epilepsy 4 | 792
Global developmental delay 4 | 608
Mental and motor retardation 4 | 608
Multiple myeloma 4 | 1,332
active ulcerative colitis 4 | 764
astrocytic glioma 4 | 2,597
cystic fibrosis 4 | 1,696
interstitial cystitis 4 | 2,312
invasive ductal carcinoma 4 | 2,951
juvenile dermatomyositis 4 | 1,187
pediatric high grade glioma 4 | 1,064
pituitary cancer 4 | 1,972
progressive supranuclear palsy 4 | 676
tuberculosis 4 | 2,010
Seizures 3 | 596
Small head 3 | 374
Waldenstrons macroglobulinemia 3 | 765
acute quadriplegic myopathy 3 | 1,158
dermatomyositis 3 | 966
diabetes mellitus 3 | 1,728
gastric carcinoma 3 | 807
primary Sjogren syndrome 3 | 735
subependymal giant cell astrocytoma 3 | 2,287
ulcerative colitis 3 | 1,819
Agenesis of corpus callosum 2 | 83
Byzanthine arch palate 2 | 194
Cerebellar Hypoplasia 2 | 61
Chronic Lymphocytic Leukemia 2 | 262
Cobblestone Lissencephaly 2 | 8
Congenital disorder of glycosylation 2 | 54
Congenital muscular dystrophy 2 | 29
Creatine phosphokinase serum increased 2 | 110
Dandy-Walker Syndrome 2 | 39
Down syndrome 2 | 499
Dull intelligence 2 | 645
Elevated creatine kinase 2 | 110
Hydrocephalus 2 | 152
Hypoplasia of corpus callosum 2 | 90
Hypoplasia of the brainstem 2 | 22
Hypotonia, severe 2 | 33
Intellectual disability 2 | 1,016
Lissencephaly 2 | 69
Liver neoplasms 2 | 130
Low intelligence 2 | 645
Melanoma 2 | 711
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Microcephaly 2 | 166
Muscle Hypertonia 2 | 88
Muscle biopsy shows dystrophic changes 2 | 39
Muscle hypotonia 2 | 571
Muscular Dystrophy-Dystroglycanopathy (Congenital With Brain and Eye Anomalies), Type A, 1 2 | 6
Muscular dystrophy 2 | 75
Optic Atrophy 2 | 242
Poor school performance 2 | 645
Retinal Dysplasia 2 | 11
Strabismus 2 | 270
Walker-Warburg congenital muscular dystrophy 2 | 14
Walker-Warburg syndrome 2 | 20
aldosterone-producing adenoma 2 | 665
colon cancer 2 | 1,478
fibroadenoma 2 | 559
hepatocellular carcinoma 2 | 547
nasopharyngeal carcinoma 2 | 1,058
non diabetic and post-ischemic heart failure 2 | 200
pancreatic cancer 2 | 2,398
primary pancreatic ductal adenocarcinoma 2 | 1,109
spina bifida 2 | 1,074
tuberculosis and treatment for 3 months 2 | 179

Tissue

Endocrine System 44 | 18,159
Nervous System 44 | 16,725
Cardiovascular System 43 | 15,192
Digestive Tract 43 | 17,369
Female tissues 43 | 17,400
Liver and Pancreas 43 | 16,750
Male tissues 43 | 17,142
Respiratory system 43 | 16,393
Skin and soft tissues 43 | 17,230
Urinary Tract 43 | 16,678
Blood and immune system 42 | 16,909

Target Family

Enzyme 23 | 4,145
Non-IDG 17 | 12,091
Transporter 5 | 473

Compartment GO Term

Integral component of Golgi me... 45 | 45
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
UbiA prenyltransferase domain-containing protein 1 UBIAD1 Tbio Enzyme -1.59893 42.5 50
Alkaline ceramidase 3 ACER3 Tbio Enzyme -2.07938 117.1 95
Protein unc-50 homolog UNC50 Tdark Non-IDG -0.96776 11.0 38
Meiosis-specific nuclear structural protein 1 MNS1 Tbio Non-IDG -1.18603 14.1 68
Phosphatidylcholine:ceramide cholinephosphotransferase 1 SGMS1 Tchem Enzyme -1.61164 41.6 0
Phosphatidylcholine:ceramide cholinephosphotransferase 2 SGMS2 Tchem Enzyme -1.45924 31.1 204
Metalloreductase STEAP2 STEAP2 Tbio Enzyme -1.78852 56.5 154
Polypeptide N-acetylgalactosaminyltransferase 2 GALNT2 Tbio Enzyme -1.44267 31.1 106
Sulfhydryl oxidase 2 QSOX2 Tbio Enzyme -0.86091 6.47 64
Golgi apparatus membrane protein TVP23 homolog B TVP23B Tdark Non-IDG 0.15 1.13 24