Development Level

Tbio 40 | 11,445
Tclin 2 | 613
Tdark 2 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 8 | 979
cataract 3 | 92
embryonic lethality prior to o... 3 | 239
abnormal behavior 2 | 298
brachydactyly 2 | 19
embryonic lethality prior to t... 2 | 278
hyperactivity 2 | 148
increased fasted circulating g... 2 | 76
increased total body fat amoun... 2 | 134
prenatal lethality prior to he... 2 | 87
syndactyly 2 | 23
abnormal lens morphology 1 | 81
abnormal retina morphology 1 | 71
abnormal retinal vasculature m... 1 | 27
abnormal sleep behavior 1 | 70
absent startle reflex 1 | 24
convulsive seizures 1 | 13
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased cardiac stroke volum... 1 | 6
decreased circulating LDL chol... 1 | 38
decreased circulating creatini... 1 | 39
decreased total body fat amoun... 1 | 207
impaired glucose tolerance 1 | 75
increased anti-nuclear antigen... 1 | 19
increased body length 1 | 32
increased bone mineral content 1 | 108
increased circulating glucose ... 1 | 24
increased lean body mass 1 | 172
microphthalmia 1 | 26

Disease

ovarian cancer 27 | 8,520
Carcinoma 23 | 11,493
osteosarcoma 23 | 7,950
psoriasis 17 | 6,694
lung cancer 16 | 4,740
atypical teratoid / rhabdoid tumor 13 | 5,112
ependymoma 13 | 4,679
glioblastoma 13 | 5,792
medulloblastoma, large-cell 13 | 6,241
Multiple myeloma 11 | 1,332
Breast cancer 10 | 3,578
Cancer 9 | 2,499
astrocytic glioma 9 | 2,597
diabetes mellitus 9 | 1,728
group 3 medulloblastoma 9 | 4,104
adult high grade glioma 8 | 3,801
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
Alzheimer's disease 7 | 658
Pick disease 7 | 1,894
lung adenocarcinoma 7 | 2,716
malignant mesothelioma 7 | 3,232
non-small cell lung cancer 7 | 2,890
oligodendroglioma 7 | 2,850
Astrocytoma, Pilocytic 6 | 3,081
Deafness dystonia syndrome 6 | 21
Dystonia 6 | 164
Neurodegenerative disease 6 | 414
Optic Atrophy 6 | 242
Vascular disease 6 | 319
tuberculosis 6 | 2,010
Heart disease 5 | 306
Kidney cancer 5 | 2,613
Kidney disease 5 | 430
Obesity 5 | 678
Waldenstrons macroglobulinemia 5 | 765
cystic fibrosis 5 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
Autosomal recessive predisposition 4 | 1,442
Cerebrovascular disease 4 | 238
Hyperglycemia 4 | 137
Hypertension 4 | 396
Rheumatoid arthritis 4 | 1,191
Toxic encephalopathy 4 | 141
acute myeloid leukemia 4 | 783
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
invasive ductal carcinoma 4 | 2,951
medulloblastoma 4 | 720
pancreatic cancer 4 | 2,398
pituitary cancer 4 | 1,972
subependymal giant cell astrocytoma 4 | 2,287
Anemia 3 | 365
Atherosclerosis 3 | 291
Barth syndrome 3 | 23
Bipolar Disorder 3 | 666
Brain Ischemia 3 | 110
Brain disease 3 | 96
Congenital adrenal hyperplasia 3 | 73
Congenital adrenal insufficiency 3 | 7
Epilepsy 3 | 792
Eye disease 3 | 62
Major Depressive Disorder 3 | 301
Polycystic ovary syndrome 3 | 360
Schizophrenia 3 | 1,160
Sleeping sickness 3 | 37
adrenocortical carcinoma 3 | 1,428
interstitial lung disease 3 | 298
non primary Sjogren syndrome sicca 3 | 891
posterior fossa group B ependymoma 3 | 416
primitive neuroectodermal tumor 3 | 3,035
ulcerative colitis 3 | 1,819
3-methylglutaconic aciduria 2 | 29
Anteverted nostril 2 | 191
Atrophy of cerebellum 2 | 103
Cerebellar degeneration 2 | 103
Coronary artery disease 2 | 268
Delayed bone age 2 | 136
Dementia 2 | 175
Hyperandrogenism 2 | 34
Hyperreflexia 2 | 209
Hypersensitivity reaction type II disease 2 | 253
Malaria 2 | 160
Muscle Spasticity 2 | 195
Myopathy 2 | 185
Parkinson's disease 2 | 392
Seizures 2 | 596
Short nose 2 | 132
Small nose 2 | 132
Strabismus 2 | 270
Unipolar Depression 2 | 250
aldosterone-producing adenoma 2 | 665
astrocytoma 2 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
breast carcinoma 2 | 1,638
juvenile dermatomyositis 2 | 1,187
limb girdle muscular dystrophy 2A 2 | 213
primary pancreatic ductal adenocarcinoma 2 | 1,109
progressive supranuclear palsy 2 | 676
pulmonary arterial hypertension 2 | 75
spina bifida 2 | 1,074

Tissue

Digestive Tract 45 | 17,369
Endocrine System 45 | 18,159
Female tissues 45 | 17,400
Liver and Pancreas 45 | 16,750
Blood and immune system 44 | 16,909
Male tissues 44 | 17,142
Nervous System 44 | 16,725
Respiratory system 44 | 16,393
Skin and soft tissues 44 | 17,230
Urinary Tract 44 | 16,678
Cardiovascular System 43 | 15,192

Target Family

Enzyme 22 | 4,145
Non-IDG 22 | 12,091
Ion Channel 1 | 344

Compartment GO Term

Inner membrane complex 45 | 45
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

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