Development Level

Tbio 80 | 11,445
Tchem 17 | 1,598
Tdark 7 | 6,588
Tclin 2 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 7 | 979
decreased leukocyte cell numbe... 3 | 73
decreased mean platelet volume 3 | 25
decreased total body fat amoun... 3 | 207
decreased vertical activity 3 | 208
embryonic lethality prior to t... 3 | 278
increased mean corpuscular hem... 3 | 96
male infertility 3 | 123
abnormal behavior 2 | 298
abnormal behavioral response t... 2 | 66
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
decreased basophil cell number 2 | 16
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased circulating HDL chol... 2 | 68
decreased circulating alanine ... 2 | 47
decreased circulating choleste... 2 | 93
decreased circulating glucose ... 2 | 126
decreased erythrocyte cell num... 2 | 62
decreased grip strength 2 | 116
decreased mean corpuscular hem... 2 | 50
decreased neutrophil cell numb... 2 | 42
embryonic lethality prior to o... 2 | 239
improved glucose tolerance 2 | 79
increased blood urea nitrogen ... 2 | 48
increased circulating LDL chol... 2 | 13
increased circulating alkaline... 2 | 122
increased circulating bilirubi... 2 | 16
increased circulating chloride... 2 | 41
increased hematocrit 2 | 46
increased mean corpuscular hem... 2 | 36
increased mean platelet volume 2 | 45
increased total body fat amoun... 2 | 134
preweaning lethality, incomple... 2 | 499
abnormal coat- hair morphology 1 | 19
abnormal forebrain development 1 | 20
abnormal heart morphology 1 | 162
abnormal hindbrain development 1 | 16
abnormal neural tube closure 1 | 46
abnormal sleep behavior 1 | 70
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
absent startle reflex 1 | 24
convulsive seizures 1 | 13
cyanosis 1 | 7
decreased anxiety-related resp... 1 | 12
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased circulating LDL chol... 1 | 38
decreased circulating bilirubi... 1 | 19
decreased circulating fructosa... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased heart left ventricle... 1 | 28
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased mean corpuscular vol... 1 | 79
decreased red blood cell distr... 1 | 41
decreased threshold for audito... 1 | 26
edema 1 | 59
enlarged heart 1 | 210
female infertility 1 | 60
hemorrhage 1 | 23
hyperactivity 1 | 148
hypoactivity 1 | 132
increased aggression 1 | 4
increased body length 1 | 32
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating aspartat... 1 | 15
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased erythrocyte cell num... 1 | 39
increased exploration in new e... 1 | 8
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased prepulse inhibition 1 | 32
increased red blood cell distr... 1 | 34
polycystic kidney 1 | 15
premature death 1 | 5
prenatal lethality 1 | 28
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
respiratory system phenotype 1 | 2
small testis 1 | 58
thin ventricular wall 1 | 24
thrombocytosis 1 | 27

Disease

Carcinoma 74 | 11,493
ovarian cancer 61 | 8,520
osteosarcoma 53 | 7,950
medulloblastoma, large-cell 46 | 6,241
glioblastoma 42 | 5,792
psoriasis 42 | 6,694
atypical teratoid / rhabdoid tumor 41 | 5,112
Neurodegenerative disease 39 | 414
lung cancer 38 | 4,740
Cancer 35 | 2,499
ependymoma 34 | 4,679
group 3 medulloblastoma 33 | 4,104
oligodendroglioma 32 | 2,850
astrocytic glioma 30 | 2,597
malignant mesothelioma 30 | 3,232
adult high grade glioma 29 | 3,801
Alzheimer's disease 28 | 658
Dementia 28 | 175
Amyotrophic lateral sclerosis 24 | 451
Kidney cancer 24 | 2,613
Astrocytoma, Pilocytic 22 | 3,081
Pick disease 22 | 1,894
Multiple myeloma 21 | 1,332
Parkinson's disease 21 | 392
diabetes mellitus 21 | 1,728
primitive neuroectodermal tumor 21 | 3,035
Depressive disorder 20 | 409
Breast cancer 19 | 3,578
Nerve Degeneration 19 | 121
subependymal giant cell astrocytoma 19 | 2,287
Dysarthria 18 | 192
Toxic encephalopathy 18 | 141
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,989
lung carcinoma 18 | 2,843
tuberculosis 18 | 2,010
Autosomal recessive predisposition 16 | 1,442
Schizophrenia 16 | 1,160
colon cancer 16 | 1,478
acute quadriplegic myopathy 15 | 1,158
pituitary cancer 15 | 1,972
Parkinsonian Disorders 14 | 56
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
invasive ductal carcinoma 14 | 2,951
Anxiety 13 | 136
Anxiety disease 13 | 113
Deglutition Disorders 13 | 132
Multiple system atrophy 13 | 29
Neurodegenerative Disorders 13 | 79
Waldenstrons macroglobulinemia 13 | 765
non-small cell lung cancer 13 | 2,890
Frontotemporal dementia 12 | 51
Muscle Spasticity 12 | 195
dermatomyositis 12 | 966
juvenile dermatomyositis 12 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
Brain disease 11 | 96
Hyperreflexia 11 | 209
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
lung adenocarcinoma 11 | 2,716
progressive supranuclear palsy 11 | 676
ulcerative colitis 11 | 1,819
Adult onset 10 | 82
Bipolar Disorder 10 | 666
Huntington's disease 10 | 76
cystic fibrosis 10 | 1,696
group 4 medulloblastoma 10 | 1,855
non primary Sjogren syndrome sicca 10 | 891
pancreatic cancer 10 | 2,398
Aphasia 9 | 26
Bradykinesia 9 | 34
Down syndrome 9 | 499
Epilepsy 9 | 792
Gait abnormality 9 | 135
Mental Depression 9 | 333
Mood swings 9 | 77
Muscle Cramp 9 | 55
Muscle Rigidity 9 | 49
Neuro-degenerative disease 9 | 43
Paralysed 9 | 42
Parkinson Disease 9 | 64
Personality change 9 | 23
Respiratory Failure 9 | 104
Seizures 9 | 596
interstitial cystitis 9 | 2,312
Amyloidosis 8 | 67
Babinski Reflex 8 | 100
Duchenne muscular dystrophy 8 | 601
Dyspnea 8 | 76
Dystonia 8 | 164
Fatigue 8 | 182
Generalized muscle weakness 8 | 57
Neurogenic Muscular Atrophy 8 | 139
Neurogenic muscle atrophy, especially in the lower limbs 8 | 139
Neuronal loss 8 | 25
Pain 8 | 103
Pick's disease 8 | 15
Progressive disorder 8 | 142
Skeletal muscle atrophy 8 | 139
acute myeloid leukemia 8 | 783
muscle degeneration 8 | 139

Tissue

Digestive Tract 104 | 17,369
Endocrine System 104 | 18,159
Female tissues 104 | 17,400
Skin and soft tissues 104 | 17,230
Blood and immune system 103 | 16,909
Urinary Tract 103 | 16,678
Liver and Pancreas 102 | 16,750
Male tissues 101 | 17,142
Nervous System 101 | 16,725
Respiratory system 98 | 16,393
Cardiovascular System 96 | 15,192

Target Family

Non-IDG 65 | 12,091
Enzyme 22 | 4,145
Kinase 7 | 634
Transcription Factor 5 | 1,400
Epigenetic 4 | 242
Transporter 2 | 473
TF/Epigenetic 1 | 38

Compartment GO Term

Inclusion body 106 | 106
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nesprin-2 SYNE2 Tbio Non-IDG -2.62747 380.6 39
Huntingtin HTT Tchem Non-IDG -3.36282 2294.8 599
14-3-3 protein theta YWHAQ Tchem Non-IDG -2.43493 235.4 358
PHD finger protein 1 PHF1 Tbio Epigenetic -2.14039 127.5 199
Polyadenylate-binding protein 2 PABPN1 Tbio Non-IDG -2.48757 316.4 120
Gamma-synuclein SNCG Tbio Non-IDG -2.24895 187.3 294
Nucleoprotein TPR TPR Tbio Non-IDG -2.11491 135.6 161
Tripartite motif-containing protein 66 TRIM66 Tdark Epigenetic -0.11394 2.15 17
E3 ubiquitin-protein ligase TRIM37 TRIM37 Tbio Enzyme -3.25892 1754.8 177
Tubulin polymerization-promoting protein TPPP Tbio Non-IDG -1.95532 92.5 179