Development Level

Tbio 27 | 10,625
Tdark 6 | 7,003
Tchem 2 | 1,890

IMPC Phenotype

preweaning lethality, complete... 9 | 633
embryonic lethality prior to o... 5 | 148
embryonic lethality prior to t... 3 | 187
abnormal behavior 2 | 226
decreased body weight 2 | 174
abnormal QRS complex 1 | 25
abnormal cornea morphology 1 | 24
abnormal embryo size 1 | 112
abnormal eye morphology 1 | 38
abnormal eye size 1 | 11
abnormal hindbrain development 1 | 24
abnormal locomotor activation 1 | 26
abnormal maxilla morphology 1 | 16
abnormal neural tube closure 1 | 37
abnormal seminal vesicle morph... 1 | 47
abnormal tooth morphology 1 | 24
abnormal vocalization 1 | 21
anophthalmia 1 | 20
decreased circulating insulin ... 1 | 75
decreased circulating magnesiu... 1 | 11
decreased lean body mass 1 | 195
hypoactivity 1 | 89
increased body length 1 | 20
increased body weight 1 | 42
increased circulating magnesiu... 1 | 10
increased grip strength 1 | 83
increased heart weight 1 | 37
increased mean corpuscular vol... 1 | 91
microphthalmia 1 | 15
pale yolk sac 1 | 12
preweaning lethality, incomple... 1 | 260
straub tail 1 | 26

Disease

ovarian cancer 23 | 8,491
lung cancer 18 | 4,473
osteosarcoma 14 | 7,933
psoriasis 12 | 6,685
Cancer 11 | 2,346
medulloblastoma, large-cell 11 | 6,234
atypical teratoid / rhabdoid tumor 10 | 4,369
glioblastoma 10 | 5,572
lung adenocarcinoma 10 | 2,714
malignant mesothelioma 10 | 3,163
Multiple myeloma 9 | 1,327
Breast cancer 8 | 3,098
Carcinoma 8 | 2,147
dermatomyositis 8 | 966
group 3 medulloblastoma 8 | 2,254
primitive neuroectodermal tumor 8 | 3,031
Waldenstrons macroglobulinemia 7 | 764
colon cancer 7 | 1,475
invasive ductal carcinoma 7 | 2,950
oligodendroglioma 6 | 2,849
Intellectual disability 5 | 573
acute myeloid leukemia 5 | 785
diabetes mellitus 5 | 1,663
group 4 medulloblastoma 5 | 1,875
non-small cell lung cancer 5 | 2,798
pediatric high grade glioma 5 | 2,712
ductal carcinoma in situ 4 | 1,745
ependymoma 4 | 2,514
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,289
pilocytic astrocytoma 4 | 3,086
spina bifida 4 | 1,064
Alpha thalassemia 3 | 10
Cleft palate 3 | 125
Cockayne syndrome 3 | 54
Connective tissue disease 3 | 59
Leishmaniasis 3 | 49
Lupus erythematosus 3 | 80
Rheumatoid Arthritis 3 | 1,170
Schimke immuno-osseous dysplasia 3 | 9
adrenocortical carcinoma 3 | 1,427
adult high grade glioma 3 | 2,148
astrocytic glioma 3 | 2,241
astrocytoma 3 | 1,493
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
juvenile dermatomyositis 3 | 1,189
posterior fossa group A ependymoma 3 | 1,511
Adenoid Cystic Carcinoma 2 | 99
Alzheimer's disease 2 | 644
Coffin-Siris syndrome 2 | 17
Dental caries 2 | 67
Enamel erosion 2 | 15
Endometriosis 2 | 535
Gaucher disease type 1 2 | 171
Gingivitis 2 | 19
Kidney cancer 2 | 121
Parkinson's disease 2 | 364
Pick disease 2 | 1,893
Schizophrenia 2 | 503
Spondyloepiphyseal dysplasia with congenital joint dislocations 2 | 12
Thyroiditis 2 | 25
acute quadriplegic myopathy 2 | 1,157
aldosterone-producing adenoma 2 | 664
breast carcinoma 2 | 1,614
hereditary spastic paraplegia 2 | 313
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,956
lung carcinoma 2 | 2,844
medulloblastoma 2 | 1,524
non primary Sjogren syndrome sicca 2 | 840
pancreatic cancer 2 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
sonic hedgehog group medulloblastoma 2 | 1,482
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis and treatment for 6 months 2 | 686
ulcerative colitis 2 | 2,087
Amyotrophic Lateral Sclerosis 1 | 432
Atopic dermatitis 1 | 944
Cardiovascular system disease 1 | 194
Coronary artery disease 1 | 240
Coronary heart disease 1 | 59
Disease Progression 1 | 125
HIV Infections 1 | 99
Hypotrichosis 1 | 29
IGA Glomerulonephritis 1 | 454
Influenza 1 | 142
Leukopenia 1 | 42
Malaria 1 | 140
Prostate cancer 1 | 172
Retinitis pigmentosa 1 | 156
Rubinstein-Taybi syndrome 1 | 11
Uterine Cervical Neoplasm 1 | 21
Venous Thromboembolism 1 | 34
active Crohn's disease 1 | 918
active ulcerative colitis 1 | 477
adrenocortical adenoma 1 | 134
atypical teratoid/rhabdoid tumor 1 | 1,095
cystic fibrosis 1 | 1,670
hepatocellular carcinoma 1 | 550
nasopharyngeal carcinoma 1 | 1,056
progressive supranuclear palsy 1 | 674
substance-related disorder 1 | 104

Tissue

Blood and immune system 35 | 17,994
Cardiovascular System 35 | 17,957
Digestive Tract 35 | 18,472
Endocrine System 35 | 18,511
Female tissues 35 | 18,646
Liver and Pancreas 35 | 18,135
Male tissues 35 | 17,968
Nervous System 35 | 18,560
Respiratory system 35 | 17,483
Skin and soft tissues 35 | 18,114
Urinary Tract 35 | 18,443

Target Family

Non-IDG 24 | 11,969
Epigenetic 6 | 242
Enzyme 4 | 4,146
Transcription Factor 1 | 1,400

Compartment GO Term

INO80-type complex 35 | 35
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger HIT domain-containing protein 1 ZNHIT1 Tdark Non-IDG -0.29003 1.92 92
INO80 complex subunit B INO80B Tdark Non-IDG -1.09962 12.3 46
INO80 complex subunit C INO80C Tdark Non-IDG 0.00000 16
E1A-binding protein p400 EP400 Tbio Non-IDG -1.45388 26.7 53
Histone H2A.Z H2AFZ Tbio Non-IDG -2.48248 304.4 245
Chromodomain-helicase-DNA-binding protein 1 CHD1 Tbio Epigenetic -2.10739 133.8 113
Bromodomain-containing protein 8 BRD8 Tbio Epigenetic -0.56055 5.02 106
Histone acetyltransferase KAT5 KAT5 Tbio Epigenetic -2.24545 178.0 450
Actin-like protein 6A ACTL6A Tbio Non-IDG -1.40144 24.0 269
Actin-related protein 8 ACTR8 Tdark Non-IDG 0.23 0.78 17