Development Level

Tchem 4 | 1,598
Tbio 1 | 11,445

Disease

Cancer 4 | 2,499
Carcinoma 3 | 11,493
lung cancer 3 | 4,740
Asthma 2 | 385
Atopic dermatitis 2 | 952
Heat Stroke 2 | 13
Pneumonia 2 | 174
Rheumatoid arthritis 2 | 1,191
diabetes mellitus 2 | 1,728
gastric carcinoma 2 | 807
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
osteosarcoma 2 | 7,950
ovarian cancer 2 | 8,520
pancreatic cancer 2 | 2,398
psoriasis 2 | 6,694
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
ASTHMA-RELATED TRAITS, SUSCEPTIBILITY TO, 5 1 | 1
Abnormalities, Multiple 1 | 13
Absence of B cells 1 | 4
Absent B cells 1 | 4
Absent mandible 1 | 6
Anemia, Hemolytic 1 | 55
Autoimmune thrombocytopenia 1 | 22
Blastic phase chronic myeloid leukemia 1 | 58
Bone Diseases, Developmental 1 | 27
Brachycephaly 1 | 88
Broad cranium shape 1 | 88
Bronchiectasis 1 | 64
Chromosome 1q21.1 deletion syndrome 1 | 12
Chronic Myelocytic Leukemia Accelerated Phase 1 | 59
Chronic otitis media 1 | 52
Common variable immunodeficiency 1 | 101
Congenital absence of jaw 1 | 3
Congenital absence of mandible 1 | 3
Decreased antibody level in blood 1 | 35
Decreased circulating ACTH level 1 | 12
Down syndrome 1 | 499
Dystrophia unguium 1 | 53
Elevated hepatic transaminases 1 | 81
Fatigue 1 | 182
Hepatic enzyme increased 1 | 81
Highly variable severity 1 | 157
Hypogammaglobulinemia 1 | 35
Hypoglycemic coma 1 | 10
Hyponatremia 1 | 25
Hypoplasia involving bones of the upper limbs 1 | 3
Hypotension 1 | 82
Idiopathic thrombocytopenia 1 | 22
Immune thrombocytopenic purpura 1 | 24
Immunologic Deficiency Syndromes 1 | 113
Infectious disease of lung 1 | 29
Limb Deformities, Congenital 1 | 16
Liver Dysfunction 1 | 99
Liver enzymes abnormal 1 | 81
Liver function test increased 1 | 81
Liver function tests abnormal finding 1 | 81
Low to undetectable plasma cortisol 1 | 12
Lung Neoplasms 1 | 232
Lymphadenopathy 1 | 62
Lymphoma, T-Cell, Cutaneous 1 | 22
Lymphopenia 1 | 67
Mantle cell lymphoma 1 | 23
Multiple pulmonary infections 1 | 29
Popliteal pterygium syndrome 1 | 6
Protrusion of tongue 1 | 11
Purpura 1 | 43
Reactive airway disease 1 | 21
Recurrent bronchitis 1 | 23
Recurrent hypoglycemia 1 | 4
Recurrent otitis media 1 | 42
Recurrent pneumonia 1 | 29
Recurrent pulmonary infections 1 | 29
Recurrent respiratory infections 1 | 141
Recurrent sinus disease 1 | 22
Recurrent sinusitis 1 | 22
Reperfusion Injury 1 | 86
Secondary Adrenal Insufficiency 1 | 6
Skin Abnormalities 1 | 37
Subclinical abnormal liver function tests 1 | 81
Theileriasis 1 | 13
Thin skin 1 | 47
Transaminases increased 1 | 81
Type 2 diabetes mellitus 1 | 272
Variable expressivity 1 | 157
Wide skull shape 1 | 88
active Crohn's disease 1 | 922
adrenocortical carcinoma 1 | 1,428
ear infection chronic 1 | 52
hepatocellular carcinoma 1 | 547
lung adenocarcinoma 1 | 2,716
medulloblastoma 1 | 720
nephrosclerosis 1 | 333
pancreatic carcinoma 1 | 562
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
pharyngitis recurrent 1 | 4
pituitary cancer 1 | 1,972
tuberculosis and treatment for 6 months 1 | 409

Tissue

Blood and immune system 5 | 16,909
Cardiovascular System 5 | 15,192
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678

Target Family

Kinase 3 | 634
Transcription Factor 2 | 1,400

Compartment GO Term

IKKalpha-IKKalpha complex 5 | 5
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mitogen-activated protein kinase kinase kinase kinase 4 MAP4K4 Tchem Kinase -2.19064 152.6 547
Interleukin-1 receptor-associated kinase 3 IRAK3 Tchem Kinase -1.86631 84.0 427
Nuclear factor NF-kappa-B p100 subunit NFKB2 Tchem Transcription Factor -2.29577 191.3 637
Inhibitor of nuclear factor kappa-B kinase subunit alpha CHUK Tchem Kinase -2.36360 203.6 1101
Transcription factor RelB RELB Tbio Transcription Factor -2.47061 292.2 455