Development Level

Tbio 81 | 11,445
Tclin 10 | 613
Tchem 8 | 1,598
Tdark 8 | 6,588

Collection

Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Comple... 1 | 37
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 12 | 979
abnormal bone structure 3 | 187
abnormal embryo size 3 | 220
decreased circulating glucose ... 3 | 126
decreased vertical activity 3 | 208
edema 3 | 59
preweaning lethality, incomple... 3 | 499
abnormal tail morphology 2 | 25
cyanosis 2 | 7
decreased blood urea nitrogen ... 2 | 51
decreased bone mineral content 2 | 151
decreased circulating choleste... 2 | 93
decreased grip strength 2 | 116
decreased lean body mass 2 | 135
decreased neutrophil cell numb... 2 | 42
embryonic lethality prior to t... 2 | 278
hemorrhage 2 | 23
hypoactivity 2 | 132
increased body weight 2 | 25
increased heart weight 2 | 62
increased startle reflex 2 | 112
respiratory system phenotype 2 | 2
abnormal QT variability 1 | 10
abnormal bone mineralization 1 | 38
abnormal facial morphology 1 | 17
abnormal heart morphology 1 | 162
abnormal joint morphology 1 | 23
abnormal limb morphology 1 | 13
abnormal placenta vasculature 1 | 2
abnormal response to new envir... 1 | 10
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal urinary bladder morph... 1 | 11
abnormal vocalization 1 | 21
brachydactyly 1 | 19
cardiovascular system phenotyp... 1 | 36
decreased NK cell number 1 | 2
decreased T cell number 1 | 15
decreased basophil cell number 1 | 16
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating amylase ... 1 | 28
decreased circulating creatini... 1 | 39
decreased circulating free fat... 1 | 31
decreased circulating fructosa... 1 | 30
decreased circulating iron lev... 1 | 32
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased heart left ventricle... 1 | 28
decreased heart rate variabili... 1 | 13
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mature B cell number 1 | 7
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
female infertility 1 | 60
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased body temperature 1 | 9
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating chloride... 1 | 41
increased circulating triglyce... 1 | 42
increased heart rate 1 | 23
increased mean corpuscular vol... 1 | 92
increased respiratory quotient 1 | 2
increased spleen weight 1 | 10
increased vertical activity 1 | 24
male infertility 1 | 123
prenatal lethality 1 | 28
short tibia 1 | 97
shortened PQ interval 1 | 7
shortened PR interval 1 | 6
shortened ST segment 1 | 10
syndactyly 1 | 23
thin ventricular wall 1 | 24
thrombocytosis 1 | 27
tremors 1 | 39

Disease

Carcinoma 83 | 11,493
ovarian cancer 54 | 8,520
psoriasis 49 | 6,694
glioblastoma 42 | 5,792
medulloblastoma, large-cell 42 | 6,241
atypical teratoid / rhabdoid tumor 40 | 5,112
lung cancer 40 | 4,740
Breast cancer 34 | 3,578
osteosarcoma 33 | 7,950
lung adenocarcinoma 32 | 2,716
pancreatic cancer 32 | 2,398
Kidney cancer 31 | 2,613
ependymoma 31 | 4,679
adult high grade glioma 30 | 3,801
colon cancer 29 | 1,478
lung carcinoma 29 | 2,843
invasive ductal carcinoma 28 | 2,951
non-small cell lung cancer 27 | 2,890
malignant mesothelioma 26 | 3,232
acute quadriplegic myopathy 25 | 1,158
group 3 medulloblastoma 25 | 4,104
primitive neuroectodermal tumor 25 | 3,035
Myopathy 24 | 185
intraductal papillary-mucinous neoplasm (IPMN) 24 | 3,291
Astrocytoma, Pilocytic 23 | 3,081
Autosomal recessive predisposition 23 | 1,442
Cardiomyopathy 23 | 116
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 21 | 2,955
oligodendroglioma 21 | 2,850
Dilated cardiomyopathy 20 | 56
Liver cancer 18 | 604
astrocytic glioma 18 | 2,597
breast carcinoma 18 | 1,638
Cardiomyopathy, Dilated 17 | 83
Familial isolated dilated cardiomyopathy 17 | 41
LEFT VENTRICULAR NONCOMPACTION 10 17 | 40
LEFT VENTRICULAR NONCOMPACTION 8 17 | 40
ductal carcinoma in situ 17 | 1,745
group 4 medulloblastoma 16 | 1,855
tuberculosis 16 | 2,010
Hypertrophic Cardiomyopathy 15 | 117
subependymal giant cell astrocytoma 15 | 2,287
Endometrial cancer 14 | 311
Heart disease 14 | 306
Pick disease 14 | 1,894
pituitary cancer 14 | 1,972
Creatine phosphokinase serum increased 13 | 110
Elevated creatine kinase 13 | 110
Skin cancer 13 | 469
cystic fibrosis 13 | 1,696
ulcerative colitis 13 | 1,819
Atrial Fibrillation 12 | 124
Melanoma 12 | 711
Muscular dystrophy 12 | 75
adrenocortical carcinoma 12 | 1,428
Cancer 11 | 2,499
Muscle biopsy shows dystrophic changes 11 | 39
dermatomyositis 11 | 966
spina bifida 11 | 1,074
Duchenne muscular dystrophy 10 | 601
astrocytoma 10 | 1,146
juvenile dermatomyositis 10 | 1,187
Amyotrophic lateral sclerosis 9 | 451
Epilepsy 9 | 792
active ulcerative colitis 9 | 764
primary pancreatic ductal adenocarcinoma 9 | 1,109
Acquired scoliosis 8 | 281
Atopic dermatitis 8 | 952
Bell Palsy 8 | 58
Bipolar Disorder 8 | 666
Cardiac Arrhythmia 8 | 103
Cardiomyopathies 8 | 110
Congestive heart failure 8 | 113
Curvature of spine 8 | 282
Facial Paresis 8 | 59
Facial muscle weakness of muscles innervated by CN VII 8 | 58
Intellectual disability 8 | 1,016
Motor delay 8 | 147
No development of motor milestones 8 | 147
Seizures 8 | 596
Syncope 8 | 22
active Crohn's disease 8 | 922
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 510
limb-girdle muscular dystrophy 8 | 37
nasopharyngeal carcinoma 8 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
pediatric high grade glioma 8 | 1,064
Contracture 7 | 96
Contracture of joint 7 | 93
Decreased tendon reflex 7 | 122
Dull intelligence 7 | 645
Flexion contracture 7 | 93
Flexion contractures of joints 7 | 93
Large intestine cancer 7 | 126
Respiratory Insufficiency 7 | 132
Slow progression 7 | 89
cutaneous lupus erythematosus 7 | 1,057
diabetes mellitus 7 | 1,728
hereditary spastic paraplegia 7 | 318

Tissue

Endocrine System 107 | 18,159
Digestive Tract 106 | 17,369
Female tissues 106 | 17,400
Male tissues 104 | 17,142
Nervous System 104 | 16,725
Skin and soft tissues 104 | 17,230
Urinary Tract 104 | 16,678
Blood and immune system 103 | 16,909
Liver and Pancreas 102 | 16,750
Cardiovascular System 100 | 15,192
Respiratory system 100 | 16,393

Target Family

Non-IDG 74 | 12,091
Enzyme 14 | 4,145
Ion Channel 11 | 344
Transporter 4 | 473
Kinase 3 | 634
Epigenetic 1 | 242

Compartment GO Term

I band 107 | 107
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,237 | 12,237
Intracellular organelle 12,023 | 12,023
membrane-bounded organelle 11,130 | 11,130
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,340 | 10,340
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,561 | 7,561
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,972 | 3,972
non-membrane-bounded organelle 3,972 | 3,972
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,955 | 1,955
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,547 | 1,547
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,123 | 1,123
Nuclear outer membrane-endopla... 1,121 | 1,121
Nucleoplasm part 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,040 | 1,040
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 949 | 949
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 848 | 848
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tripartite motif-containing protein 54 TRIM54 Tbio Non-IDG -1.55520 36.7 243
Desmin DES Tbio Non-IDG -1.56068 36.6 991
Sorcin SRI Tbio Non-IDG -2.69915 481.5 119
Immunoglobulin-like and fibronectin type III domain-containing protein 1 IGFN1 Tdark Non-IDG -0.41218 2.92 66
Immunoglobulin superfamily member 22 IGSF22 Tdark Non-IDG 0.48 0.33 16
Myocardial zonula adherens protein POLR2M Tbio Non-IDG -1.87592 70.6 20
Palladin PALLD Tbio Non-IDG -2.73002 528.8 164
Myomesin-1 MYOM1 Tbio Non-IDG -1.21420 16.8 127
Nesprin-2 SYNE2 Tbio Non-IDG -2.62747 380.6 39
BAG family molecular chaperone regulator 3 BAG3 Tbio Non-IDG -2.26339 208.9 289