Development Level

Tchem 2 | 1,598

Disease

Carcinoma 2 | 11,493
Distal limb muscle weakness due to peripheral neuropathy 2 | 62
Distal muscle weakness 2 | 62
Distal sensory impairment 2 | 52
Distal sensory impairment of all modalities 2 | 7
Hereditary Sensory Autonomic Neuropathy, Type 1 2 | 4
Neuropathy 2 | 261
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
ovarian cancer 2 | 8,520
psoriasis 2 | 6,694
tuberculosis 2 | 2,010
Absent reflex 1 | 92
Absent tendon reflex 1 | 92
Alopecia universalis 1 | 16
Alzheimer's disease 1 | 658
Anhidrosis 1 | 23
Aortic Valve Insufficiency 1 | 40
Astrocytoma, Pilocytic 1 | 3,081
Autoamputation 1 | 2
Autoamputation of foot 1 | 2
Bipolar Disorder 1 | 666
Chronic axonal neuropathy 1 | 2
Congenital pes cavus 1 | 88
Decreased sensory nerve conduction velocities (NCV) 1 | 8
Decreased tendon reflex 1 | 122
Depletion of large myelinated fibers 1 | 7
Dermatologic disorders 1 | 93
Dysesthesia 1 | 6
Foot Deformities 1 | 30
Hereditary sensory and autonomic neuropathy type IC 1 | 1
Infection of bone 1 | 19
Lumbosacral lipoma 1 | 3
Multiple Sclerosis 1 | 540
Multiple myeloma 1 | 1,332
NEUROPATHY, HEREDITARY SENSORY AND AUTONOMIC, TYPE IA 1 | 1
NEUROPATHY, HEREDITARY SENSORY AND AUTONOMIC, TYPE IC 1 | 1
Neurodegenerative disease 1 | 414
Neurogenic Muscular Atrophy 1 | 139
Neurogenic muscle atrophy, especially in the lower limbs 1 | 139
Neuropathy, Hereditary Sensory and Autonomic, Type 1A 1 | 1
Osteomyelitis 1 | 42
Osteomyelitis or necrosis, distal, due to sensory neuropathy (feet) 1 | 2
Peripheral sensorimotor neuropathy 1 | 16
Reflex, Deep Tendon, Absent 1 | 92
Sensorineural Hearing Loss (disorder) 1 | 284
Skeletal muscle atrophy 1 | 139
Skin Abnormalities 1 | 37
Skin Ulcer 1 | 48
Tabes dorsalis 1 | 6
acute quadriplegic myopathy 1 | 1,158
adult high grade glioma 1 | 3,801
aldosterone-producing adenoma 1 | 665
astrocytic glioma 1 | 2,597
atypical teratoid / rhabdoid tumor 1 | 5,112
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 510
cutaneous lupus erythematosus 1 | 1,057
glioblastoma 1 | 5,792
group 4 medulloblastoma 1 | 1,855
hepatocellular carcinoma 1 | 547
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
juvenile dermatomyositis 1 | 1,187
lung adenocarcinoma 1 | 2,716
medulloblastoma, large-cell 1 | 6,241
muscle degeneration 1 | 139
non-small cell lung cancer 1 | 2,890
osteosarcoma 1 | 7,950
pancreatic cancer 1 | 2,398
primary pancreatic ductal adenocarcinoma 1 | 1,109
subependymal giant cell astrocytoma 1 | 2,287

Tissue

Blood and immune system 2 | 16,909
Cardiovascular System 2 | 15,192
Digestive Tract 2 | 17,369
Endocrine System 2 | 18,159
Female tissues 2 | 17,400
Liver and Pancreas 2 | 16,750
Male tissues 2 | 17,142
Nervous System 2 | 16,725
Respiratory system 2 | 16,393
Skin and soft tissues 2 | 17,230
Urinary Tract 2 | 16,678

Target Family

Enzyme 2 | 4,145

Compartment GO Term

Homodimeric serine palmitoyltr... 2 | 2
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine palmitoyltransferase 1 SPTLC1 Tchem Enzyme -2.16711 143.2 285
Serine palmitoyltransferase 2 SPTLC2 Tchem Enzyme -1.70805 49.3 203