Development Level

Tbio 59 | 11,445
Tchem 22 | 1,598
Tdark 5 | 6,588
Tclin 3 | 613

IMPC Phenotype

preweaning lethality, complete... 15 | 979
decreased total body fat amoun... 5 | 207
preweaning lethality, incomple... 5 | 499
abnormal behavior 4 | 298
embryonic lethality prior to o... 4 | 239
increased lean body mass 4 | 172
abnormal embryo size 3 | 220
abnormal lens morphology 3 | 81
cataract 3 | 92
abnormal bone structure 2 | 187
abnormal cornea morphology 2 | 31
abnormal retina morphology 2 | 71
corneal opacity 2 | 32
decreased blood urea nitrogen ... 2 | 51
decreased body weight 2 | 161
decreased bone mineral density 2 | 126
decreased circulating alanine ... 2 | 47
decreased grip strength 2 | 116
decreased mean corpuscular vol... 2 | 79
hypoactivity 2 | 132
impaired pupillary reflex 2 | 26
increased bone mineral content 2 | 108
increased bone mineral density 2 | 72
increased total body fat amoun... 2 | 134
irregularly shaped pupil 2 | 7
microphthalmia 2 | 26
prenatal lethality prior to he... 2 | 87
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal craniofacial morpholo... 1 | 33
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal heart morphology 1 | 162
abnormal iris morphology 1 | 13
abnormal maxilla morphology 1 | 17
abnormal optic disc morphology 1 | 10
abnormal pericardium morpholog... 1 | 26
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal tooth morphology 1 | 24
absent spleen 1 | 3
anophthalmia 1 | 33
decreased body length 1 | 101
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating serum al... 1 | 82
decreased heart left ventricle... 1 | 28
decreased lean body mass 1 | 135
decreased prepulse inhibition 1 | 82
decreased respiratory quotient 1 | 16
decreased startle reflex 1 | 75
decreased total retina thickne... 1 | 17
decreased vertical activity 1 | 208
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged heart 1 | 210
enlarged spleen 1 | 41
enlarged urinary bladder 1 | 8
fusion of vertebral arches 1 | 7
hemorrhage 1 | 23
impaired glucose tolerance 1 | 75
increased CD4-positive, alpha ... 1 | 4
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased cardiac muscle contr... 1 | 8
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating glucose ... 1 | 24
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased circulating triglyce... 1 | 42
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased startle reflex 1 | 112
increased thermal nociceptive ... 1 | 9
male infertility 1 | 123
mydriasis 1 | 6
persistence of hyaloid vascula... 1 | 33
prolonged QRS complex duration 1 | 8
short tibia 1 | 97
small heart 1 | 10
small kidney 1 | 16
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 19
vertebral fusion 1 | 23
vertebral transformation 1 | 12

Disease

Carcinoma 68 | 11,493
ovarian cancer 51 | 8,520
osteosarcoma 45 | 7,950
Cancer 39 | 2,499
group 3 medulloblastoma 35 | 4,104
lung cancer 29 | 4,740
psoriasis 29 | 6,694
atypical teratoid / rhabdoid tumor 28 | 5,112
medulloblastoma, large-cell 28 | 6,241
Kidney cancer 26 | 2,613
malignant mesothelioma 26 | 3,232
glioblastoma 25 | 5,792
Breast cancer 20 | 3,578
primitive neuroectodermal tumor 18 | 3,035
Intellectual disability 17 | 1,016
ependymoma 17 | 4,679
invasive ductal carcinoma 15 | 2,951
adult high grade glioma 13 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
non-small cell lung cancer 13 | 2,890
oligodendroglioma 12 | 2,850
Pick disease 11 | 1,894
astrocytic glioma 11 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
Liver cancer 10 | 604
acute quadriplegic myopathy 10 | 1,158
adrenocortical carcinoma 10 | 1,428
pancreatic cancer 10 | 2,398
Multiple myeloma 9 | 1,332
Rheumatoid arthritis 9 | 1,191
Schizophrenia 9 | 1,160
juvenile dermatomyositis 9 | 1,187
Kabuki syndrome 8 | 27
Melanoma 8 | 711
Muscle hypotonia 8 | 571
breast carcinoma 8 | 1,638
lung adenocarcinoma 8 | 2,716
subependymal giant cell astrocytoma 8 | 2,287
Adenoid Cystic Carcinoma 7 | 99
Carcinoma, Adenoid Cystic 7 | 99
Dull intelligence 7 | 645
Immune system cancer 7 | 140
Low intelligence 7 | 645
Lymphoid leukemia 7 | 160
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Poor school performance 7 | 645
astrocytoma 7 | 1,146
dermatomyositis 7 | 966
ductal carcinoma in situ 7 | 1,745
spina bifida 7 | 1,074
tuberculosis 7 | 2,010
Alzheimer's disease 6 | 658
Bladder Neoplasm 6 | 112
Breast Neoplasms 6 | 445
Mammary Neoplasms 6 | 425
Neurodevelopmental Disorders 6 | 70
Urinary Bladder Neoplasms 6 | 114
colon cancer 6 | 1,478
cystic fibrosis 6 | 1,696
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
pediatric high grade glioma 6 | 1,064
ulcerative colitis 6 | 1,819
Adenocarcinoma 5 | 122
Astrocytoma, Pilocytic 5 | 3,081
Cleft Palate 5 | 271
Cognitive delay 5 | 608
Cryptorchidism 5 | 296
Epilepsy 5 | 792
Failure to gain weight 5 | 365
Global developmental delay 5 | 608
Leukemia 5 | 104
Leukemia, Myelocytic, Acute 5 | 120
Mental and motor retardation 5 | 608
Pediatric failure to thrive 5 | 365
Seizures 5 | 596
Short stature 5 | 531
Strabismus 5 | 270
Waldenstrons macroglobulinemia 5 | 765
diabetes mellitus 5 | 1,728
interstitial cystitis 5 | 2,312
lung carcinoma 5 | 2,843
nasopharyngeal carcinoma 5 | 1,058
non primary Sjogren syndrome sicca 5 | 891
Acquired scoliosis 4 | 281
Adenoma 4 | 167
Asthma 4 | 385
Autism spectrum disorder 4 | 101
Broad flat nasal bridge 4 | 236
Byzanthine arch palate 4 | 194
Curvature of spine 4 | 282
Endometrial cancer 4 | 311
Endometriosis 4 | 540
Liver carcinoma 4 | 240
Nasal bridge wide 4 | 236
Stomach Neoplasms 4 | 300
acute myeloid leukemia 4 | 783
pituitary cancer 4 | 1,972
progressive supranuclear palsy 4 | 676

Tissue

Blood and immune system 88 | 16,909
Endocrine System 88 | 18,159
Female tissues 88 | 17,400
Male tissues 88 | 17,142
Respiratory system 88 | 16,393
Skin and soft tissues 88 | 17,230
Digestive Tract 87 | 17,369
Liver and Pancreas 87 | 16,750
Nervous System 87 | 16,725
Urinary Tract 87 | 16,678
Cardiovascular System 84 | 15,192

Target Family

Epigenetic 35 | 242
Non-IDG 35 | 12,091
Enzyme 8 | 4,145
Transcription Factor 5 | 1,400
TF/Epigenetic 4 | 38
Kinase 2 | 634

Compartment GO Term

Histone methyltransferase comp... 89 | 89
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
PAXIP1-associated glutamate-rich protein 1 PAGR1 Tbio Non-IDG -1.03602 8.61 59
PR domain zinc finger protein 4 PRDM4 Tbio TF/Epigenetic -0.87918 7.84 221
Histone deacetylase 9 HDAC9 Tclin Epigenetic -2.27309 185.2 431
DPY30 domain-containing protein 1 DYDC1 Tbio Non-IDG -0.70377 5.09 133
PHD finger protein 1 PHF1 Tbio Epigenetic -2.14039 127.5 199
Ribosomal biogenesis protein LAS1L LAS1L Tdark Non-IDG -0.48801 2.91 109
Histone-lysine N-methyltransferase SETD7 SETD7 Tchem Epigenetic -2.13644 139.8 343
DNA (cytosine-5)-methyltransferase 1 DNMT1 Tclin Enzyme -3.21333 1562.7 1125
Adenylate kinase isoenzyme 6 AK6 Tbio Kinase -2.18859 223.1 91
Histone-lysine N-methyltransferase SETD2 SETD2 Tchem Epigenetic -2.83266 645.3 214