Development Level

Tbio 59 | 10,625
Tchem 24 | 1,890
Tdark 7 | 7,003
Tclin 3 | 602

IMPC Term

preweaning lethality, complete... 8 | 633
decreased total body fat amoun... 6 | 186
abnormal behavior 3 | 226
decreased body length 3 | 108
decreased rib number 3 | 59
embryonic lethality prior to o... 3 | 148
increased grip strength 3 | 83
increased lean body mass 3 | 107
preweaning lethality, incomple... 3 | 260
abnormal bone structure 2 | 131
abnormal lens morphology 2 | 73
abnormal retina morphology 2 | 100
cataract 2 | 26
decreased bone mineral content 2 | 157
decreased bone mineral density 2 | 126
decreased circulating HDL chol... 2 | 77
hypoactivity 2 | 89
increased sacral vertebrae num... 2 | 62
increased total body fat amoun... 2 | 57
short tibia 2 | 82
abnormal cornea morphology 1 | 24
abnormal embryo size 1 | 112
abnormal epididymis morphology 1 | 31
abnormal gait 1 | 51
abnormal heart left ventricle ... 1 | 20
abnormal iris morphology 1 | 12
abnormal maxilla morphology 1 | 16
abnormal retinal pigmentation 1 | 61
abnormal rib morphology 1 | 28
abnormal thoracic vertebrae mo... 1 | 16
abnormal tooth morphology 1 | 24
corneal opacity 1 | 25
decreased body weight 1 | 174
decreased circulating LDL chol... 1 | 37
decreased circulating alanine ... 1 | 53
decreased circulating alkaline... 1 | 41
decreased circulating choleste... 1 | 85
decreased circulating serum al... 1 | 79
decreased grip strength 1 | 123
decreased lean body mass 1 | 195
decreased leukocyte cell numbe... 1 | 54
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular vol... 1 | 50
decreased prepulse inhibition 1 | 52
decreased respiratory quotient 1 | 12
enlarged epididymis 1 | 27
enlarged spleen 1 | 26
fusion of vertebral arches 1 | 7
increased body length 1 | 20
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased cardiac muscle contr... 1 | 5
increased circulating creatini... 1 | 29
increased circulating serum al... 1 | 25
increased circulating triglyce... 1 | 24
increased exploration in new e... 1 | 56
increased fasted circulating g... 1 | 68
increased heart rate 1 | 17
increased mean corpuscular hem... 1 | 93
increased mean platelet volume 1 | 19
increased neutrophil cell numb... 1 | 15
male infertility 1 | 62
persistence of hyaloid vascula... 1 | 22
prenatal lethality prior to he... 1 | 64
prolonged PR interval 1 | 4
prolonged QRS complex duration 1 | 2
shortened PR interval 1 | 5
shortened RR interval 1 | 19
small heart 1 | 8
small kidney 1 | 10
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 11
vertebral fusion 1 | 23
vertebral transformation 1 | 12

Disease

ovarian cancer 55 | 8,492
osteosarcoma 47 | 7,933
Cancer 38 | 2,346
psoriasis 31 | 6,685
atypical teratoid / rhabdoid tumor 27 | 4,369
glioblastoma 27 | 5,572
lung cancer 27 | 4,473
medulloblastoma, large-cell 27 | 6,234
malignant mesothelioma 24 | 3,163
Carcinoma 22 | 2,147
group 3 medulloblastoma 22 | 2,254
primitive neuroectodermal tumor 20 | 3,031
Breast cancer 19 | 3,099
Intellectual disability 16 | 573
pediatric high grade glioma 16 | 2,712
ependymoma 15 | 2,514
invasive ductal carcinoma 15 | 2,950
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,289
non-small cell lung cancer 13 | 2,798
oligodendroglioma 13 | 2,849
Multiple myeloma 12 | 1,328
Pick disease 12 | 1,893
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,988
lung adenocarcinoma 11 | 2,714
Rheumatoid Arthritis 10 | 1,171
astrocytic glioma 10 | 2,241
medulloblastoma 10 | 1,524
acute quadriplegic myopathy 9 | 1,157
adrenocortical carcinoma 9 | 1,427
astrocytoma 9 | 1,493
dermatomyositis 9 | 967
juvenile dermatomyositis 9 | 1,189
subependymal giant cell astrocytoma 9 | 2,287
breast carcinoma 8 | 1,614
colon cancer 8 | 1,475
group 4 medulloblastoma 8 | 1,875
pancreatic cancer 8 | 2,300
spina bifida 8 | 1,064
Adenoid Cystic Carcinoma 7 | 99
Alzheimer's disease 7 | 644
Melanoma 7 | 261
Waldenstrons macroglobulinemia 7 | 765
ductal carcinoma in situ 7 | 1,745
pilocytic astrocytoma 7 | 3,086
tuberculosis 7 | 1,563
Kabuki syndrome 6 | 29
Mammary Neoplasms 6 | 410
cystic fibrosis 6 | 1,670
diabetes mellitus 6 | 1,663
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
ulcerative colitis 6 | 2,087
Bladder Neoplasm 5 | 109
Leukemia 5 | 88
Liver carcinoma 5 | 217
Lymphoid leukemia 5 | 69
adult high grade glioma 5 | 2,148
atypical teratoid/rhabdoid tumor 5 | 1,095
lung carcinoma 5 | 2,844
Adenocarcinoma 4 | 115
Adenoma 4 | 165
Asthma 4 | 349
Autistic Disorder 4 | 320
Diffuse large B-cell lymphoma 4 | 42
Leukemia, Myelocytic, Acute 4 | 113
Primary cutaneous T-cell lymphoma 4 | 29
Squamous cell carcinoma of esophagus 4 | 82
Stomach Neoplasms 4 | 282
Wolf-Hirschhorn syndrome 4 | 32
acute myeloid leukemia 4 | 785
interstitial cystitis 4 | 2,299
nasopharyngeal carcinoma 4 | 1,056
non primary Sjogren syndrome sicca 4 | 840
posterior fossa group B ependymoma 4 | 1,530
progressive supranuclear palsy 4 | 674
sonic hedgehog group medulloblastoma 4 | 1,482
Amyotrophic Lateral Sclerosis 3 | 432
Carcinoma, Transitional Cell 3 | 31
Corneal staphyloma 3 | 4
Endometriosis 3 | 535
Glaucoma 3 | 135
Glioma 3 | 66
Kleefstra syndrome 3 | 9
Lung Neoplasms 3 | 171
Lupus erythematosus 3 | 80
Myeloid Leukemia 3 | 19
Neoplasm Invasiveness 3 | 127
Neoplastic Syndromes, Hereditary 3 | 48
Nerve Sheath Tumors 3 | 5
Peripheral Neuropathy 3 | 303
Precursor Cell Lymphoblastic Leukemia Lymphoma 3 | 42
Sezary Syndrome 3 | 26
Sotos syndrome 3 | 15
Vascular disease 3 | 281
Weaver syndrome 3 | 6
active ulcerative colitis 3 | 477
acute lymphocytic leukemia 3 | 25
non-small cell lung carcinoma 3 | 413
pituitary cancer 3 | 1,972
primary pancreatic ductal adenocarcinoma 3 | 1,271

Tissue

Endocrine System 92 | 18,512
Blood and immune system 91 | 17,995
Digestive Tract 91 | 18,473
Female tissues 91 | 18,647
Liver and Pancreas 91 | 18,136
Cardiovascular System 90 | 17,958
Male tissues 90 | 17,969
Nervous System 90 | 18,561
Skin and soft tissues 89 | 18,115
Urinary Tract 89 | 18,444
Respiratory system 88 | 17,484

Target Family

Non-IDG 37 | 11,969
Epigenetic 34 | 242
Enzyme 11 | 4,146
TF/Epigenetic 4 | 38
Transcription Factor 4 | 1,400
Kinase 3 | 634

Compartment GO Term

Histone methyltransferase comp... 93 | 93
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,612 | 13,612
Intracellular part 13,475 | 13,475
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,353 | 10,353
Membrane 8,871 | 8,871
Organelle part 8,169 | 8,169
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,831 | 7,831
Nucleus 7,577 | 7,577
Membrane part 6,469 | 6,469
Cytosol 6,034 | 6,034
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,930 | 4,930
Extracellular region 4,607 | 4,607
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,874 | 3,874
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,592 | 2,592
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,530 | 1,530
Cell projection 1,425 | 1,425
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,092 | 1,092
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,084 | 1,084
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 988 | 988
Nucleoli 950 | 950
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 815 | 815
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 656 | 656
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Metal-response element-binding transcription factor 2 MTF2 Tbio Epigenetic -1.74028 52.0 101
Chromodomain-helicase-DNA-binding protein 8 CHD8 Tbio Epigenetic -1.57734 41.1 65
Histone-lysine N-methyltransferase SETD7 SETD7 Tchem Epigenetic -2.09739 127.0 297
DNA (cytosine-5)-methyltransferase 1 DNMT1 Tclin Enzyme -3.16754 1415.1 1015
Adenylate kinase isoenzyme 6 AK6 Tbio Kinase -2.17566 215.0 83
Chromobox protein homolog 2 CBX2 Tchem Epigenetic -1.31842 21.1 181
Histamine N-methyltransferase HNMT Tchem Enzyme -2.85749 712.7 213
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PPP1CA Tchem Enzyme -2.15861 136.6 346
Serine/threonine-protein phosphatase PP1-beta catalytic subunit PPP1CB Tbio Enzyme -1.52305 32.4 306
DPY30 domain-containing protein 1 DYDC1 Tdark Non-IDG -0.60805 0.59 104