Development Level

Tbio 45 | 11,445
Tchem 22 | 1,598
Tclin 14 | 613
Tdark 6 | 6,588

IMPC Phenotype

preweaning lethality, complete... 7 | 979
preweaning lethality, incomple... 5 | 499
decreased bone mineral density 3 | 126
increased startle reflex 3 | 112
abnormal behavior 2 | 298
abnormal gait 2 | 69
decreased bone mineral content 2 | 151
decreased circulating HDL chol... 2 | 68
decreased circulating LDL chol... 2 | 38
decreased lean body mass 2 | 135
hypoactivity 2 | 132
increased bone mineral density 2 | 72
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
increased circulating choleste... 2 | 66
increased circulating triglyce... 2 | 42
increased grip strength 2 | 41
increased mean corpuscular hem... 2 | 36
increased total body fat amoun... 2 | 134
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal heart left ventricle ... 1 | 16
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal maxilla morphology 1 | 17
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal snout morphology 1 | 23
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
aorta stenosis 1 | 2
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased body length 1 | 101
decreased body weight 1 | 161
decreased caudal vertebrae num... 1 | 53
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating insulin ... 1 | 76
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased heart rate 1 | 18
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased lumbar vertebrae num... 1 | 2
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
decreased sacral vertebrae num... 1 | 1
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged heart 1 | 210
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
fusion of vertebral arches 1 | 7
hyperactivity 1 | 148
increased body temperature 1 | 9
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased circulating calcium ... 1 | 34
increased circulating creatini... 1 | 38
increased circulating fructosa... 1 | 13
increased circulating glycerol... 1 | 9
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased hemoglobin content 1 | 45
increased lumbar vertebrae num... 1 | 1
increased mean corpuscular hem... 1 | 96
increased prepulse inhibition 1 | 32
increased sacral vertebrae num... 1 | 1
male infertility 1 | 123
prolonged QRS complex duration 1 | 8
short tibia 1 | 97
small heart 1 | 10
small kidney 1 | 16
small liver 1 | 8
small lung 1 | 5
small seminal vesicle 1 | 10
small spleen 1 | 19
small testis 1 | 58
thin ventricular wall 1 | 24
thrombocytopenia 1 | 56
trunk curl 1 | 16
vertebral fusion 1 | 23
vertebral transformation 1 | 12

Disease

Carcinoma 62 | 11,493
osteosarcoma 56 | 7,950
Cancer 53 | 2,499
ovarian cancer 51 | 8,520
glioblastoma 35 | 5,792
psoriasis 35 | 6,694
medulloblastoma, large-cell 34 | 6,241
lung cancer 32 | 4,740
Kidney cancer 26 | 2,613
atypical teratoid / rhabdoid tumor 26 | 5,112
group 3 medulloblastoma 24 | 4,104
adult high grade glioma 22 | 3,801
Multiple myeloma 21 | 1,332
malignant mesothelioma 21 | 3,232
primitive neuroectodermal tumor 21 | 3,035
Breast cancer 20 | 3,578
Schizophrenia 20 | 1,160
ependymoma 19 | 4,679
astrocytoma 18 | 1,146
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
Intellectual disability 16 | 1,016
lung adenocarcinoma 16 | 2,716
subependymal giant cell astrocytoma 16 | 2,287
diabetes mellitus 15 | 1,728
invasive ductal carcinoma 15 | 2,951
Breast Neoplasms 14 | 445
Mammary Neoplasms 14 | 425
Obesity 14 | 678
Peripheral T-cell lymphoma 14 | 25
Prostatic Neoplasms 14 | 495
Astrocytoma, Pilocytic 13 | 3,081
Primary cutaneous T-cell lymphoma 13 | 29
astrocytic glioma 13 | 2,597
ductal carcinoma in situ 13 | 1,745
oligodendroglioma 13 | 2,850
Cognitive delay 11 | 608
Dull intelligence 11 | 645
Epilepsy 11 | 792
Global developmental delay 11 | 608
Low intelligence 11 | 645
Mental Retardation 11 | 645
Mental and motor retardation 11 | 608
Mental deficiency 11 | 645
Mood Disorders 11 | 184
Poor school performance 11 | 645
Seizures 11 | 596
breast carcinoma 11 | 1,638
Rheumatoid arthritis 10 | 1,191
Short stature 10 | 531
Squamous cell carcinoma 10 | 129
Vascular disease 10 | 319
Waldenstrons macroglobulinemia 10 | 765
acute myeloid leukemia 10 | 783
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
lung carcinoma 10 | 2,843
Carcinoma, Squamous Cell 9 | 110
Immune system cancer 9 | 140
Lymphoid leukemia 9 | 160
Stomach Neoplasms 9 | 300
adrenocortical carcinoma 9 | 1,428
non-small cell lung cancer 9 | 2,890
pancreatic cancer 9 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
Acquired scoliosis 8 | 281
Bipolar Disorder 8 | 666
Bladder Neoplasm 8 | 112
Congenital Epicanthus 8 | 177
Cryptorchidism 8 | 296
Curvature of spine 8 | 282
Endometriosis 8 | 540
Hypoplastic mandible condyle 8 | 275
Mandibular hypoplasia 8 | 275
Micrognathism 8 | 275
Muscle hypotonia 8 | 571
Pick disease 8 | 1,894
Small head 8 | 374
Strabismus 8 | 270
Urinary Bladder Neoplasms 8 | 114
acute quadriplegic myopathy 8 | 1,158
juvenile dermatomyositis 8 | 1,187
pituitary cancer 8 | 1,972
Autosomal recessive predisposition 7 | 1,442
Big calvaria 7 | 147
Colonic Neoplasms 7 | 142
Colorectal Neoplasms 7 | 243
Depressive disorder 7 | 409
Endometrial cancer 7 | 311
Feeding difficulties in infancy 7 | 175
Increased head circumference 7 | 147
Increased size of cranium 7 | 147
Increased size of skull 7 | 147
Lung Neoplasms 7 | 232
Mental Depression 7 | 333
Neurodegenerative disease 7 | 414
hearing impairment 7 | 199
medulloblastoma 7 | 720
colon cancer 6 | 1,478
dermatomyositis 6 | 966
ulcerative colitis 6 | 1,819

Tissue

Digestive Tract 85 | 17,369
Endocrine System 85 | 18,159
Female tissues 85 | 17,400
Liver and Pancreas 85 | 16,750
Male tissues 85 | 17,142
Respiratory system 85 | 16,393
Skin and soft tissues 85 | 17,230
Urinary Tract 85 | 16,678
Blood and immune system 84 | 16,909
Cardiovascular System 84 | 15,192
Nervous System 84 | 16,725

Target Family

Epigenetic 39 | 242
Non-IDG 19 | 12,091
Transcription Factor 17 | 1,400
Enzyme 10 | 4,145
Kinase 1 | 634
Nuclear Receptor 1 | 48

Compartment GO Term

Histone deacetylase complex 87 | 87
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Methyl-CpG-binding domain protein 3 MBD3 Tbio Transcription Factor -0.85800 7.92 309
Histone deacetylase 9 HDAC9 Tclin Epigenetic -2.27309 185.2 431
NAD-dependent protein deacylase sirtuin-5, mitochondrial SIRT5 Tchem Epigenetic -2.36015 219.3 427
Inhibitor of growth protein 1 ING1 Tbio Epigenetic -2.05417 130.8 341
Transcriptional-regulating factor 1 TRERF1 Tbio Transcription Factor -0.69436 6.18 146
Metastasis-associated protein MTA3 MTA3 Tbio Transcription Factor -1.36174 24.5 204
PHD finger protein 12 PHF12 Tbio Epigenetic -2.57717 385.3 70
Chromodomain-helicase-DNA-binding protein 4 CHD4 Tbio Epigenetic -2.22229 159.7 203
Breast cancer metastasis-suppressor 1-like protein BRMS1L Tbio Non-IDG -1.71309 57.0 107
DNA (cytosine-5)-methyltransferase 1 DNMT1 Tclin Enzyme -3.21333 1562.7 1125