Development Level

Tbio 66 | 11,445
Tchem 7 | 1,598
Tclin 2 | 613

IMPC Phenotype

increased startle reflex 6 | 112
preweaning lethality, complete... 5 | 979
preweaning lethality, incomple... 5 | 499
abnormal bone structure 4 | 187
increased heart weight 4 | 62
abnormal behavior 3 | 298
abnormal retina morphology 2 | 71
decreased circulating phosphat... 2 | 27
decreased hematocrit 2 | 46
decreased prepulse inhibition 2 | 82
decreased total body fat amoun... 2 | 207
increased circulating alkaline... 2 | 122
short tibia 2 | 97
thrombocytopenia 2 | 56
abnormal cranium morphology 1 | 36
abnormal femur morphology 1 | 14
abnormal sensory capabilities-... 1 | 8
abnormal spleen morphology 1 | 55
abnormal vocalization 1 | 21
cardiovascular system phenotyp... 1 | 36
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased respiratory quotient 1 | 16
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged kidney 1 | 14
hyperactivity 1 | 148
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
increased circulating HDL chol... 1 | 80
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating phosphat... 1 | 26
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
increased total body fat amoun... 1 | 134
male infertility 1 | 123
persistence of hyaloid vascula... 1 | 33
vertebral fusion 1 | 23

Disease

Carcinoma 53 | 11,493
ovarian cancer 41 | 8,520
medulloblastoma, large-cell 40 | 6,241
osteosarcoma 38 | 7,950
glioblastoma 36 | 5,792
atypical teratoid / rhabdoid tumor 29 | 5,112
lung cancer 27 | 4,740
ependymoma 26 | 4,679
psoriasis 26 | 6,694
adult high grade glioma 24 | 3,801
Astrocytoma, Pilocytic 23 | 3,081
Cancer 23 | 2,499
group 3 medulloblastoma 22 | 4,104
lung carcinoma 22 | 2,843
oligodendroglioma 20 | 2,850
Breast cancer 18 | 3,578
subependymal giant cell astrocytoma 18 | 2,287
primitive neuroectodermal tumor 17 | 3,035
Kidney cancer 16 | 2,613
astrocytic glioma 16 | 2,597
group 4 medulloblastoma 16 | 1,855
malignant mesothelioma 16 | 3,232
ulcerative colitis 16 | 1,819
non-small cell lung cancer 15 | 2,890
pancreatic cancer 15 | 2,398
Schizophrenia 14 | 1,160
invasive ductal carcinoma 14 | 2,951
Pick disease 13 | 1,894
colon cancer 13 | 1,478
pituitary cancer 13 | 1,972
Obesity 12 | 678
tuberculosis 12 | 2,010
Intellectual disability 11 | 1,016
breast carcinoma 11 | 1,638
diabetes mellitus 10 | 1,728
interstitial cystitis 10 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
lung adenocarcinoma 10 | 2,716
Kidney disease 9 | 430
Liver Cirrhosis, Experimental 9 | 769
ductal carcinoma in situ 9 | 1,745
Depressive disorder 8 | 409
Hypertension 8 | 396
astrocytoma 8 | 1,146
Bipolar Disorder 7 | 666
Multiple myeloma 7 | 1,332
Pseudohypoparathyroidism 7 | 18
Rheumatoid arthritis 7 | 1,191
active ulcerative colitis 7 | 764
acute quadriplegic myopathy 7 | 1,158
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
Asthma 6 | 385
Autosomal recessive predisposition 6 | 1,442
Cholera 6 | 34
Epilepsy 6 | 792
Fibrous dysplasia 6 | 15
Liver cancer 6 | 604
McCune Albright syndrome 6 | 19
Melanoma 6 | 711
Skin cancer 6 | 469
Substance Withdrawal Syndrome 6 | 55
cystic fibrosis 6 | 1,696
non primary Sjogren syndrome sicca 6 | 891
primary Sjogren syndrome 6 | 735
primary pancreatic ductal adenocarcinoma 6 | 1,109
ACTH-secreting pituitary adenoma 5 | 9
Adenoma 5 | 167
Beckwith-Wiedemann syndrome 5 | 44
Bone cancer 5 | 16
Crohn's disease 5 | 321
Dull intelligence 5 | 645
Heart disease 5 | 306
Hyperthyroidism 5 | 53
Hypothyroidism 5 | 122
Low intelligence 5 | 645
Mental Depression 5 | 333
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Night Blindness 5 | 101
Osteoporosis 5 | 363
Polycystic ovary syndrome 5 | 360
Poor school performance 5 | 645
Seizures 5 | 596
Stomach Neoplasms 5 | 300
Thyroid cancer 5 | 36
Vascular disease 5 | 319
active Crohn's disease 5 | 922
adrenocortical carcinoma 5 | 1,428
cutaneous lupus erythematosus 5 | 1,057
juvenile dermatomyositis 5 | 1,187
pediatric high grade glioma 5 | 1,064
Acromegaly 4 | 51
Atopic dermatitis 4 | 952
Duchenne muscular dystrophy 4 | 601
Glaucoma 4 | 239
Waldenstrons macroglobulinemia 4 | 765
mucosa-associated lymphoid tissue lymphoma 4 | 484
spina bifida 4 | 1,074
substance-related disorder 4 | 162

Tissue

Endocrine System 71 | 18,159
Skin and soft tissues 69 | 17,230
Blood and immune system 68 | 16,909
Digestive Tract 68 | 17,369
Female tissues 68 | 17,400
Nervous System 68 | 16,725
Male tissues 67 | 17,142
Liver and Pancreas 65 | 16,750
Respiratory system 64 | 16,393
Urinary Tract 64 | 16,678
Cardiovascular System 63 | 15,192

Target Family

Non-IDG 61 | 12,091
Enzyme 7 | 4,145
Kinase 4 | 634
GPCR 3 | 408

Compartment GO Term

Heterotrimeric G-protein compl... 75 | 75
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

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