Development Level

Tbio 51 | 10,625
Tchem 15 | 1,890
Tdark 3 | 7,003
Tclin 2 | 602

IMPC Term

preweaning lethality, incomple... 7 | 260
preweaning lethality, complete... 5 | 633
abnormal behavior 3 | 226
increased circulating choleste... 3 | 53
abnormal embryo size 2 | 112
abnormal gait 2 | 51
abnormal iris morphology 2 | 12
abnormal lens morphology 2 | 73
cataract 2 | 26
decreased body weight 2 | 174
decreased circulating triglyce... 2 | 83
decreased rib number 2 | 59
embryonic lethality prior to o... 2 | 148
female infertility 2 | 34
hyperactivity 2 | 108
increased circulating HDL chol... 2 | 63
increased grip strength 2 | 83
increased or absent threshold ... 2 | 128
abnormal bone structure 1 | 131
abnormal coat appearance 1 | 25
abnormal coat/hair pigmentatio... 1 | 54
abnormal maxilla morphology 1 | 16
abnormal placement of pupils 1 | 4
abnormal retina morphology 1 | 100
abnormal rib morphology 1 | 28
abnormal snout morphology 1 | 18
abnormal thoracic vertebrae mo... 1 | 16
abnormal tooth morphology 1 | 24
decreased IgG1 level 1 | 4
decreased Ly6C-positive mature... 1 | 4
decreased basophil cell number 1 | 11
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased caudal vertebrae num... 1 | 49
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating choleste... 1 | 85
decreased effector memory CD8-... 1 | 24
decreased granulocyte number 1 | 8
decreased heart rate 1 | 10
decreased heart weight 1 | 44
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular vol... 1 | 50
decreased prepulse inhibition 1 | 52
embryonic lethality prior to t... 1 | 187
enlarged heart 1 | 111
fusion of vertebral arches 1 | 7
hydrops fetalis 1 | 22
increased bone mineral density 1 | 52
increased circulating chloride... 1 | 43
increased circulating triglyce... 1 | 24
increased heart weight 1 | 37
increased mean corpuscular hem... 1 | 25
increased sacral vertebrae num... 1 | 62
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
irregularly shaped pupil 1 | 7
limb grasping 1 | 35
male infertility 1 | 62
narrow eye opening 1 | 15
prenatal lethality prior to he... 1 | 64
prolonged RR interval 1 | 2
vertebral fusion 1 | 23
vertebral transformation 1 | 12

Disease

ovarian cancer 39 | 8,484
lung cancer 36 | 4,466
medulloblastoma, large-cell 35 | 6,234
osteosarcoma 35 | 7,933
Cancer 33 | 2,346
glioblastoma 30 | 5,572
psoriasis 26 | 6,685
malignant mesothelioma 25 | 3,162
primitive neuroectodermal tumor 24 | 3,031
atypical teratoid / rhabdoid tumor 23 | 4,369
group 3 medulloblastoma 21 | 2,254
Breast cancer 20 | 3,094
Carcinoma 19 | 2,147
lung adenocarcinoma 18 | 2,713
diabetes mellitus 15 | 1,663
invasive ductal carcinoma 15 | 2,950
non-small cell lung cancer 15 | 2,798
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,289
astrocytic glioma 13 | 2,241
pediatric high grade glioma 13 | 2,712
Waldenstrons macroglobulinemia 12 | 765
oligodendroglioma 12 | 2,849
Multiple myeloma 11 | 1,327
Pick disease 11 | 1,893
adrenocortical carcinoma 11 | 1,427
pancreatic cancer 11 | 2,300
ulcerative colitis 11 | 2,087
Rheumatoid Arthritis 10 | 1,160
acute quadriplegic myopathy 10 | 1,157
ependymoma 10 | 2,514
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,956
pilocytic astrocytoma 10 | 3,086
astrocytoma 9 | 1,493
atypical teratoid/rhabdoid tumor 9 | 1,095
dermatomyositis 9 | 933
Intellectual disability 8 | 573
acute myeloid leukemia 8 | 780
colon cancer 8 | 1,475
ductal carcinoma in situ 8 | 1,745
hepatocellular carcinoma 8 | 532
lung carcinoma 8 | 2,844
Prostatic Neoplasms 7 | 471
adult high grade glioma 7 | 2,148
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,988
posterior fossa group A ependymoma 7 | 1,511
Alzheimer's disease 6 | 644
Mammary Neoplasms 6 | 410
juvenile dermatomyositis 6 | 1,189
non primary Sjogren syndrome sicca 6 | 840
subependymal giant cell astrocytoma 6 | 2,287
Craniofacial Abnormalities 5 | 147
Endometriosis 5 | 535
Lupus erythematosus 5 | 80
Melanoma 5 | 261
breast carcinoma 5 | 1,614
gastric cancer 5 | 430
group 4 medulloblastoma 5 | 1,875
medulloblastoma 5 | 1,524
nasopharyngeal carcinoma 5 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
pituitary cancer 5 | 1,972
sonic hedgehog group medulloblastoma 5 | 1,482
Adenoid Cystic Carcinoma 4 | 99
CREST syndrome 4 | 10
Crohn's disease 4 | 304
IGA Glomerulonephritis 4 | 454
Lymphoid leukemia 4 | 69
Lymphoma, T-Cell, Cutaneous 4 | 21
Male infertility 4 | 170
Pancreatic Neoplasm 4 | 79
Stomach Neoplasms 4 | 282
aldosterone-producing adenoma 4 | 664
cutaneous lupus erythematosus 4 | 1,056
cystic fibrosis 4 | 1,665
gastric carcinoma 4 | 832
primary Sjogren syndrome 4 | 789
primary pancreatic ductal adenocarcinoma 4 | 1,271
progressive supranuclear palsy 4 | 674
spina bifida 4 | 1,064
tuberculosis and treatment for 6 months 4 | 686
Acquired metabolic disease 3 | 267
Adenoma 3 | 165
Atopic dermatitis 3 | 944
Diabetes Mellitus, Non-Insulin-Dependent 3 | 157
Down syndrome 3 | 548
Infertility 3 | 163
Lung Neoplasms 3 | 171
Microcephaly 3 | 149
Multiple Sclerosis 3 | 498
Neuroblastoma 3 | 78
Neurodegenerative disease 3 | 383
Parkinson's disease 3 | 364
Polycystic Ovary Syndrome 3 | 332
Primary biliary cirrhosis 3 | 43
Vascular disease 3 | 281
hereditary spastic paraplegia 3 | 313
inflammatory breast cancer 3 | 404
interstitial cystitis 3 | 2,299
non-small cell lung carcinoma 3 | 413
sarcoidosis 3 | 358

Tissue

Endocrine System 71 | 18,512
Blood and immune system 70 | 17,995
Cardiovascular System 70 | 17,958
Digestive Tract 70 | 18,473
Female tissues 70 | 18,647
Liver and Pancreas 70 | 18,136
Male tissues 70 | 17,969
Nervous System 70 | 18,561
Respiratory system 70 | 17,484
Skin and soft tissues 70 | 18,115
Urinary Tract 70 | 18,444

Target Family

Non-IDG 29 | 11,971
Epigenetic 23 | 242
Enzyme 8 | 4,146
Transcription Factor 8 | 1,400
TF/Epigenetic 2 | 38
Kinase 1 | 634

Compartment GO Term

Heterochromatin 71 | 71
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
High mobility group protein HMGI-C HMGA2 Tbio Transcription Factor -3.21092 1667.7 216
Methyl-CpG-binding protein 2 MECP2 Tchem Transcription Factor -3.22710 1827.6 567
Histone H3-like centromeric protein A CENPA Tbio Non-IDG -2.68837 532.8 347
Ubiquitin-conjugating enzyme E2 A UBE2A Tbio Non-IDG -1.50248 30.7 117
Ubiquitin-conjugating enzyme E2 B UBE2B Tbio Non-IDG -1.56439 38.8 140
Histone H4 HIST2H4A Tbio Non-IDG -2.57230 138.5 770
E3 ubiquitin-protein ligase BRE1B RNF40 Tbio Enzyme -0.78876 5.67 173
Histone H3.3 H3F3B Tbio Non-IDG -2.06154 100.6 415
Histone-lysine N-methyltransferase KMT5C KMT5C Tdark Epigenetic 1.18 0.06 42
DNA (cytosine-5)-methyltransferase 3A DNMT3A Tclin Epigenetic -2.80919 625.6 631