Development Level

Tbio 56 | 11,445
Tchem 15 | 1,598
Tclin 2 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, incomple... 10 | 499
preweaning lethality, complete... 8 | 979
abnormal behavior 4 | 298
increased startle reflex 4 | 112
abnormal embryo size 3 | 220
decreased body weight 3 | 161
abnormal lens morphology 2 | 81
abnormal retina morphology 2 | 71
cataract 2 | 92
decreased body length 2 | 101
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating triglyce... 2 | 79
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
hemorrhage 2 | 23
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal kidney morphology 1 | 65
absent spleen 1 | 3
decreased IgG1 level 1 | 8
decreased basophil cell number 1 | 16
decreased blood urea nitrogen ... 1 | 51
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased erythrocyte cell num... 1 | 62
decreased heart left ventricle... 1 | 28
decreased heart rate 1 | 18
decreased lean body mass 1 | 135
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased spleen weight 1 | 10
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
edema 1 | 59
enlarged heart 1 | 210
female infertility 1 | 60
fusion of vertebral arches 1 | 7
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased CD4-positive, alpha ... 1 | 4
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating triglyce... 1 | 42
increased grip strength 1 | 41
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
polycystic kidney 1 | 15
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
prolonged RR interval 1 | 8
vertebral fusion 1 | 23
vertebral transformation 1 | 12

Disease

Carcinoma 54 | 11,493
ovarian cancer 42 | 8,520
Cancer 40 | 2,499
lung cancer 38 | 4,740
osteosarcoma 38 | 7,950
medulloblastoma, large-cell 35 | 6,241
glioblastoma 31 | 5,792
group 3 medulloblastoma 31 | 4,104
atypical teratoid / rhabdoid tumor 30 | 5,112
malignant mesothelioma 28 | 3,232
psoriasis 28 | 6,694
Breast cancer 25 | 3,578
primitive neuroectodermal tumor 24 | 3,035
Kidney cancer 21 | 2,613
lung adenocarcinoma 19 | 2,716
ependymoma 18 | 4,679
invasive ductal carcinoma 17 | 2,951
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,291
non-small cell lung cancer 16 | 2,890
diabetes mellitus 15 | 1,728
pancreatic cancer 15 | 2,398
adult high grade glioma 14 | 3,801
astrocytic glioma 14 | 2,597
Astrocytoma, Pilocytic 12 | 3,081
Intellectual disability 12 | 1,016
Multiple myeloma 12 | 1,332
Schizophrenia 12 | 1,160
Waldenstrons macroglobulinemia 12 | 765
oligodendroglioma 12 | 2,850
Pick disease 11 | 1,894
adrenocortical carcinoma 11 | 1,428
ulcerative colitis 11 | 1,819
acute quadriplegic myopathy 10 | 1,158
ductal carcinoma in situ 10 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
Cognitive delay 9 | 608
Global developmental delay 9 | 608
Mammary Neoplasms 9 | 425
Mental and motor retardation 9 | 608
Rheumatoid arthritis 9 | 1,191
Short stature 9 | 531
astrocytoma 9 | 1,146
colon cancer 9 | 1,478
dermatomyositis 9 | 966
hepatocellular carcinoma 9 | 547
lung carcinoma 9 | 2,843
Breast Neoplasms 8 | 445
Dull intelligence 8 | 645
Liver cancer 8 | 604
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Poor school performance 8 | 645
acute myeloid leukemia 8 | 783
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
Concave bridge of nose 7 | 195
Depressed nasal bridge 7 | 195
Depressed nasal root/bridge 7 | 195
Hypotrophic malar bone 7 | 129
Immune system cancer 7 | 140
Lymphoid leukemia 7 | 160
Malar flattening 7 | 129
Prostatic Neoplasms 7 | 495
breast carcinoma 7 | 1,638
Alzheimer's disease 6 | 658
Big calvaria 6 | 147
Cryptorchidism 6 | 296
Decreased projection of midface 6 | 105
Endometriosis 6 | 540
Epilepsy 6 | 792
Hypoplastic mandible condyle 6 | 275
Hypotrophic midface 6 | 105
Increased head circumference 6 | 147
Increased size of cranium 6 | 147
Increased size of skull 6 | 147
Lupus erythematosus 6 | 57
Mandibular hypoplasia 6 | 275
Melanoma 6 | 711
Micrognathism 6 | 275
Midface retrusion 6 | 105
Orbital separation excessive 6 | 244
Seizures 6 | 596
Small head 6 | 374
Small midface 6 | 105
juvenile dermatomyositis 6 | 1,187
nasopharyngeal carcinoma 6 | 1,058
non primary Sjogren syndrome sicca 6 | 891
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
pediatric high grade glioma 6 | 1,064
pituitary cancer 6 | 1,972
subependymal giant cell astrocytoma 6 | 2,287
Failure to gain weight 5 | 365
Low set ears 5 | 181
Macrostomia 5 | 72
Muscle hypotonia 5 | 571
Pediatric failure to thrive 5 | 365
Stomach Neoplasms 5 | 300
cystic fibrosis 5 | 1,696
gastric cancer 5 | 459
spina bifida 5 | 1,074

Tissue

Digestive Tract 73 | 17,369
Endocrine System 73 | 18,159
Female tissues 73 | 17,400
Blood and immune system 72 | 16,909
Male tissues 72 | 17,142
Urinary Tract 72 | 16,678
Liver and Pancreas 71 | 16,750
Nervous System 71 | 16,725
Skin and soft tissues 71 | 17,230
Respiratory system 70 | 16,393
Cardiovascular System 69 | 15,192

Target Family

Non-IDG 31 | 12,091
Epigenetic 23 | 242
Transcription Factor 9 | 1,400
Enzyme 8 | 4,145
TF/Epigenetic 2 | 38
Kinase 1 | 634

Compartment GO Term

Heterochromatin 74 | 74
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone-lysine N-methyltransferase KMT5C KMT5C Tchem Epigenetic 1.18 0.06 46
E3 ubiquitin-protein ligase UHRF2 UHRF2 Tbio Epigenetic -1.57250 40.4 202
Bromodomain adjacent to zinc finger domain protein 2A BAZ2A Tchem TF/Epigenetic -2.07564 115.2 51
Origin recognition complex subunit 2 ORC2 Tbio Non-IDG -0.68275 4.92 168
Histone H1.5 HIST1H1B Tbio Non-IDG -2.13224 134.1 103
DNA (cytosine-5)-methyltransferase 1 DNMT1 Tclin Enzyme -3.21333 1562.7 1125
TP53-binding protein 1 TP53BP1 Tbio Epigenetic -2.69485 464.8 577
Ubiquitin-conjugating enzyme E2 A UBE2A Tbio Non-IDG -1.53597 32.3 117
High mobility group protein HMGI-C HMGA2 Tbio Transcription Factor -3.26377 1794.1 235
Forkhead box protein C1 FOXC1 Tbio Transcription Factor -2.28586 201.8 314