Development Level

Tbio 51 | 10,625
Tchem 15 | 1,890
Tdark 3 | 7,003
Tclin 2 | 602

IMPC Term

preweaning lethality, incomple... 7 | 260
preweaning lethality, complete... 5 | 633
abnormal behavior 3 | 226
increased circulating choleste... 3 | 53
abnormal embryo size 2 | 112
abnormal gait 2 | 51
abnormal iris morphology 2 | 12
abnormal lens morphology 2 | 73
cataract 2 | 26
decreased body weight 2 | 174
decreased circulating triglyce... 2 | 83
decreased rib number 2 | 59
embryonic lethality prior to o... 2 | 148
female infertility 2 | 34
hyperactivity 2 | 108
increased circulating HDL chol... 2 | 63
increased grip strength 2 | 83
increased or absent threshold ... 2 | 128
abnormal bone structure 1 | 131
abnormal coat appearance 1 | 25
abnormal coat/hair pigmentatio... 1 | 54
abnormal maxilla morphology 1 | 16
abnormal placement of pupils 1 | 4
abnormal retina morphology 1 | 100
abnormal rib morphology 1 | 28
abnormal snout morphology 1 | 18
abnormal thoracic vertebrae mo... 1 | 16
abnormal tooth morphology 1 | 24
decreased IgG1 level 1 | 4
decreased Ly6C-positive mature... 1 | 4
decreased basophil cell number 1 | 11
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased caudal vertebrae num... 1 | 49
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating choleste... 1 | 85
decreased effector memory CD8-... 1 | 24
decreased granulocyte number 1 | 8
decreased heart rate 1 | 10
decreased heart weight 1 | 44
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular vol... 1 | 50
decreased prepulse inhibition 1 | 52
embryonic lethality prior to t... 1 | 187
enlarged heart 1 | 111
fusion of vertebral arches 1 | 7
hydrops fetalis 1 | 22
increased bone mineral density 1 | 52
increased circulating chloride... 1 | 43
increased circulating triglyce... 1 | 24
increased heart weight 1 | 37
increased mean corpuscular hem... 1 | 25
increased sacral vertebrae num... 1 | 62
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
irregularly shaped pupil 1 | 7
limb grasping 1 | 35
male infertility 1 | 62
narrow eye opening 1 | 15
prenatal lethality prior to he... 1 | 64
prolonged RR interval 1 | 2
vertebral fusion 1 | 23
vertebral transformation 1 | 12

Disease

ovarian cancer 39 | 8,492
lung cancer 36 | 4,473
medulloblastoma, large-cell 35 | 6,234
osteosarcoma 35 | 7,933
Cancer 33 | 2,346
glioblastoma 30 | 5,572
psoriasis 26 | 6,685
malignant mesothelioma 25 | 3,163
primitive neuroectodermal tumor 24 | 3,031
atypical teratoid / rhabdoid tumor 23 | 4,369
group 3 medulloblastoma 21 | 2,254
Breast cancer 20 | 3,099
Carcinoma 19 | 2,147
lung adenocarcinoma 18 | 2,714
diabetes mellitus 15 | 1,663
invasive ductal carcinoma 15 | 2,950
non-small cell lung cancer 15 | 2,798
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,289
astrocytic glioma 13 | 2,241
pediatric high grade glioma 13 | 2,712
Waldenstrons macroglobulinemia 12 | 765
oligodendroglioma 12 | 2,849
Multiple myeloma 11 | 1,328
Pick disease 11 | 1,893
adrenocortical carcinoma 11 | 1,427
pancreatic cancer 11 | 2,300
ulcerative colitis 11 | 2,087
Rheumatoid Arthritis 10 | 1,171
acute quadriplegic myopathy 10 | 1,157
ependymoma 10 | 2,514
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,956
pilocytic astrocytoma 10 | 3,086
astrocytoma 9 | 1,493
atypical teratoid/rhabdoid tumor 9 | 1,095
dermatomyositis 9 | 967
hepatocellular carcinoma 9 | 550
Intellectual disability 8 | 573
acute myeloid leukemia 8 | 785
colon cancer 8 | 1,475
ductal carcinoma in situ 8 | 1,745
lung carcinoma 8 | 2,844
Prostatic Neoplasms 7 | 471
adult high grade glioma 7 | 2,148
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,988
posterior fossa group A ependymoma 7 | 1,511
Alzheimer's disease 6 | 644
Mammary Neoplasms 6 | 410
juvenile dermatomyositis 6 | 1,189
non primary Sjogren syndrome sicca 6 | 840
subependymal giant cell astrocytoma 6 | 2,287
Craniofacial Abnormalities 5 | 147
Endometriosis 5 | 535
Lupus erythematosus 5 | 80
Melanoma 5 | 261
breast carcinoma 5 | 1,614
gastric cancer 5 | 436
group 4 medulloblastoma 5 | 1,875
medulloblastoma 5 | 1,524
nasopharyngeal carcinoma 5 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
pituitary cancer 5 | 1,972
sonic hedgehog group medulloblastoma 5 | 1,482
Adenoid Cystic Carcinoma 4 | 99
CREST syndrome 4 | 10
Crohn's disease 4 | 304
IGA Glomerulonephritis 4 | 454
Lymphoid leukemia 4 | 69
Lymphoma, T-Cell, Cutaneous 4 | 21
Male infertility 4 | 170
Pancreatic Neoplasm 4 | 79
Stomach Neoplasms 4 | 282
aldosterone-producing adenoma 4 | 664
cutaneous lupus erythematosus 4 | 1,056
cystic fibrosis 4 | 1,670
gastric carcinoma 4 | 832
primary Sjogren syndrome 4 | 789
primary pancreatic ductal adenocarcinoma 4 | 1,271
progressive supranuclear palsy 4 | 674
spina bifida 4 | 1,064
tuberculosis and treatment for 6 months 4 | 686
Acquired metabolic disease 3 | 267
Adenoma 3 | 165
Atopic dermatitis 3 | 944
Diabetes Mellitus, Non-Insulin-Dependent 3 | 161
Down syndrome 3 | 548
Glaucoma 3 | 135
Infertility 3 | 163
Microcephaly 3 | 149
Multiple Sclerosis 3 | 498
Neuroblastoma 3 | 78
Neurodegenerative disease 3 | 383
Parkinson's disease 3 | 364
Polycystic Ovary Syndrome 3 | 335
Primary cutaneous T-cell lymphoma 3 | 29
Type 2 diabetes mellitus 3 | 192
Vascular disease 3 | 281
hereditary spastic paraplegia 3 | 313
inflammatory breast cancer 3 | 404
interstitial cystitis 3 | 2,299
non-small cell lung carcinoma 3 | 413

Tissue

Endocrine System 71 | 18,512
Blood and immune system 70 | 17,995
Cardiovascular System 70 | 17,958
Digestive Tract 70 | 18,473
Female tissues 70 | 18,647
Liver and Pancreas 70 | 18,136
Male tissues 70 | 17,969
Nervous System 70 | 18,561
Respiratory system 70 | 17,484
Skin and soft tissues 70 | 18,115
Urinary Tract 70 | 18,444

Target Family

Non-IDG 29 | 11,969
Epigenetic 23 | 242
Enzyme 8 | 4,146
Transcription Factor 8 | 1,400
TF/Epigenetic 2 | 38
Kinase 1 | 634

Compartment GO Term

Heterochromatin 71 | 71
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,612 | 13,612
Intracellular part 13,475 | 13,475
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,353 | 10,353
Membrane 8,871 | 8,871
Organelle part 8,169 | 8,169
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,831 | 7,831
Nucleus 7,577 | 7,577
Membrane part 6,469 | 6,469
Cytosol 6,034 | 6,034
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,930 | 4,930
Extracellular region 4,607 | 4,607
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,874 | 3,874
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,592 | 2,592
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,530 | 1,530
Cell projection 1,425 | 1,425
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,092 | 1,092
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,084 | 1,084
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 988 | 988
Nucleoli 950 | 950
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 815 | 815
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 656 | 656
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Bromodomain adjacent to zinc finger domain protein 2A BAZ2A Tchem TF/Epigenetic -2.05410 110.9 33
Histone H1.5 HIST1H1B Tbio Non-IDG -2.12143 127.3 70
DNA (cytosine-5)-methyltransferase 1 DNMT1 Tclin Enzyme -3.16754 1415.1 1015
DNA-binding protein Ikaros IKZF1 Tbio Transcription Factor -2.63376 453.1 351
Condensin-2 complex subunit D3 NCAPD3 Tbio Non-IDG -1.13531 12.8 118
Origin recognition complex subunit 2 ORC2 Tbio Non-IDG -0.55226 3.38 154
Lamin-B receptor LBR Tbio Epigenetic -3.00772 1003.7 120
E3 ubiquitin-protein ligase UHRF2 UHRF2 Tbio Epigenetic -1.53825 36.6 184
Ribosomal RNA-processing protein 8 RRP8 Tbio Enzyme -2.24766 174.5 99
Protein argonaute-1 AGO1 Tbio Non-IDG -2.19140 151.3 170