Development Level

Tbio 53 | 11,178
Tchem 15 | 1,885
Tclin 2 | 612
Tdark 2 | 6,569

IMPC Phenotype

preweaning lethality, incomple... 9 | 499
preweaning lethality, complete... 8 | 979
abnormal behavior 4 | 298
increased startle reflex 4 | 112
abnormal embryo size 3 | 220
decreased body weight 3 | 161
abnormal lens morphology 2 | 81
abnormal retina morphology 2 | 71
cataract 2 | 92
decreased bone mineral content 2 | 151
decreased circulating triglyce... 2 | 79
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
hemorrhage 2 | 23
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal kidney morphology 1 | 65
absent spleen 1 | 3
decreased IgG1 level 1 | 8
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased erythrocyte cell num... 1 | 62
decreased heart left ventricle... 1 | 28
decreased lean body mass 1 | 135
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased spleen weight 1 | 10
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
enlarged heart 1 | 210
fusion of vertebral arches 1 | 7
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased CD4-positive, alpha ... 1 | 4
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating triglyce... 1 | 42
increased grip strength 1 | 41
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
polycystic kidney 1 | 15
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
vertebral fusion 1 | 23
vertebral transformation 1 | 12

Disease

Carcinoma 52 | 11,192
ovarian cancer 41 | 8,297
Cancer 40 | 2,388
lung cancer 38 | 4,607
osteosarcoma 37 | 7,766
medulloblastoma, large-cell 34 | 6,086
glioblastoma 30 | 5,635
group 3 medulloblastoma 30 | 4,002
atypical teratoid / rhabdoid tumor 29 | 4,971
malignant mesothelioma 27 | 3,135
psoriasis 27 | 6,514
Breast cancer 25 | 3,469
primitive neuroectodermal tumor 23 | 2,957
Kidney cancer 20 | 2,548
lung adenocarcinoma 19 | 2,627
ependymoma 17 | 4,559
invasive ductal carcinoma 17 | 2,867
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,204
non-small cell lung cancer 16 | 2,799
diabetes mellitus 15 | 1,683
pancreatic cancer 15 | 2,322
astrocytic glioma 14 | 2,530
adult high grade glioma 13 | 3,701
Multiple myeloma 12 | 1,296
Schizophrenia 12 | 1,136
Waldenstrons macroglobulinemia 12 | 742
oligodendroglioma 12 | 2,768
Astrocytoma, Pilocytic 11 | 3,006
Intellectual disability 11 | 998
Pick disease 11 | 1,856
adrenocortical carcinoma 11 | 1,385
ulcerative colitis 11 | 1,765
acute quadriplegic myopathy 10 | 1,133
ductal carcinoma in situ 10 | 1,686
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,872
Cognitive delay 9 | 596
Global developmental delay 9 | 596
Mammary Neoplasms 9 | 403
Mental and motor retardation 9 | 596
Short stature 9 | 514
colon cancer 9 | 1,428
dermatomyositis 9 | 941
hepatocellular carcinoma 9 | 536
lung carcinoma 9 | 2,755
Breast Neoplasms 8 | 423
Liver cancer 8 | 589
Rheumatoid arthritis 8 | 1,156
acute myeloid leukemia 8 | 760
astrocytoma 8 | 1,113
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,902
Concave bridge of nose 7 | 191
Depressed nasal bridge 7 | 191
Depressed nasal root/bridge 7 | 191
Dull intelligence 7 | 634
Hypotrophic malar bone 7 | 129
Immune system cancer 7 | 136
Low intelligence 7 | 634
Lymphoid leukemia 7 | 156
Malar flattening 7 | 129
Mental Retardation 7 | 634
Mental deficiency 7 | 634
Poor school performance 7 | 634
Prostatic Neoplasms 7 | 472
breast carcinoma 7 | 1,589
Alzheimer's disease 6 | 640
Big calvaria 6 | 147
Decreased projection of midface 6 | 104
Endometriosis 6 | 521
Epilepsy 6 | 775
Hypoplastic mandible condyle 6 | 273
Hypotrophic midface 6 | 104
Increased head circumference 6 | 147
Increased size of cranium 6 | 147
Increased size of skull 6 | 147
Lupus erythematosus 6 | 56
Mandibular hypoplasia 6 | 273
Micrognathism 6 | 273
Midface retrusion 6 | 104
Orbital separation excessive 6 | 240
Seizures 6 | 584
Small midface 6 | 104
nasopharyngeal carcinoma 6 | 1,024
non primary Sjogren syndrome sicca 6 | 861
pediatric high grade glioma 6 | 1,035
subependymal giant cell astrocytoma 6 | 2,230
Failure to gain weight 5 | 359
Low set ears 5 | 178
Macrostomia 5 | 70
Melanoma 5 | 689
Muscle hypotonia 5 | 562
Pediatric failure to thrive 5 | 359
Recurrent respiratory infections 5 | 138
Small head 5 | 366
Stomach Neoplasms 5 | 287
cystic fibrosis 5 | 1,629
gastric cancer 5 | 445
juvenile dermatomyositis 5 | 1,147
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,911
pituitary cancer 5 | 1,915
spina bifida 5 | 1,053

Tissue

Blood and immune system 71 | 16,909
Digestive Tract 71 | 17,369
Endocrine System 71 | 18,159
Female tissues 71 | 17,400
Male tissues 70 | 17,142
Urinary Tract 70 | 16,678
Liver and Pancreas 69 | 16,750
Nervous System 69 | 16,725
Respiratory system 69 | 16,393
Skin and soft tissues 69 | 17,230
Cardiovascular System 67 | 15,192

Target Family

Non-IDG 31 | 12,091
Epigenetic 22 | 242
Enzyme 8 | 4,145
Transcription Factor 8 | 1,400
TF/Epigenetic 2 | 38
Kinase 1 | 634

Compartment GO Term

Heterochromatin 72 | 72
cellular_component 17,863 | 17,863
Cell 15,779 | 15,779
Cell part 15,778 | 15,778
Intracellular 13,764 | 13,764
Intracellular part 13,630 | 13,630
Organelle 11,921 | 11,921
Intracellular organelle 11,712 | 11,712
membrane-bounded organelle 10,823 | 10,823
Cytoplasm 10,720 | 10,720
Intracellular membrane-bounded... 10,057 | 10,057
Cytoplasmic part 9,029 | 9,029
Organelle part 8,755 | 8,755
Intracellular organelle part 8,566 | 8,566
Membrane 8,335 | 8,335
Nucleus 7,336 | 7,336
Cytosol 6,551 | 6,551
Membrane part 6,403 | 6,403
Plasma membrane 5,682 | 5,682
Macromolecular complex 5,345 | 5,345
Intrinsic component of membran... 5,320 | 5,320
Cell periphery 5,248 | 5,248
Integral component of membrane 5,197 | 5,197
Nucleoplasm 4,931 | 4,931
Intracellular organelle lumen 4,923 | 4,923
Organelle lumen 4,923 | 4,923
membrane-enclosed lumen 4,923 | 4,923
Nuclear part 4,169 | 4,169
Endomembrane system 4,108 | 4,108
Intracellular non-membrane-bou... 3,917 | 3,917
non-membrane-bounded organelle 3,917 | 3,917
Nuclear lumen 3,851 | 3,851
Protein complex 3,565 | 3,565
Organelle membrane 2,798 | 2,798
Extracellular region 2,600 | 2,600
Plasma membrane part 2,531 | 2,531
Vesicle 2,280 | 2,280
Cytoplasmic vesicle 2,158 | 2,158
Intracellular vesicle 2,157 | 2,157
Cytoskeleton 2,084 | 2,084
Bounding membrane of organelle 1,924 | 1,924
Endoplasmic reticulum 1,922 | 1,922
Golgi apparatus 1,884 | 1,884
Intrinsic component of plasma ... 1,701 | 1,701
Integral component of plasma m... 1,647 | 1,647
Cytoskeletal part 1,613 | 1,613
Catalytic complex 1,592 | 1,592
Vesicles 1,566 | 1,566
Mitochondrion 1,557 | 1,557
Extracellular region part 1,533 | 1,533
Cell projection 1,524 | 1,524
Whole membrane 1,521 | 1,521
Cytoplasmic vesicle part 1,468 | 1,468
Endoplasmic reticulum part 1,315 | 1,315
GO:0031975 1,139 | 1,139
Organelle envelope 1,131 | 1,131
Microtubule cytoskeleton 1,127 | 1,127
Nucleoplasm part 1,100 | 1,100
Nuclear outer membrane-endopla... 1,094 | 1,094
Endoplasmic reticulum membrane 1,076 | 1,076
Extracellular space 1,059 | 1,059
Mitochondrial part 1,027 | 1,027
Chromosome 1,020 | 1,020
Mitochondria 985 | 985
Neuron part 958 | 958
Supramolecular polymer 950 | 950
Cell junction 949 | 949
Supramolecular complex 949 | 949
Supramolecular fiber 942 | 942
Secretory vesicle 930 | 930
Golgi apparatus part 923 | 923
Nucleoli 923 | 923
Nucleolus 916 | 916
Endosome 915 | 915
Chromosomal part 872 | 872
GO:0098796 868 | 868
Ribonucleoprotein complex 845 | 845
Cell projection part 838 | 838
Transferase complex 837 | 837
Intracellular ribonucleoprotei... 830 | 830
Plasma membrane region 826 | 826
Secretory granule 810 | 810
Cell surface 805 | 805
Vesicle membrane 786 | 786
Cytoplasmic vesicle membrane 780 | 780
Polymeric cytoskeletal fiber 753 | 753
Mitochondrial envelope 739 | 739
Golgi membrane 715 | 715
Microtubule organizing center 712 | 712
Nuclear body 708 | 708
Vacuole 708 | 708
Neuron projection 701 | 701
Mitochondrial membrane 689 | 689
Centrosome 685 | 685
Extracellular matrix 670 | 670
Receptor complex 670 | 670
Synapse 656 | 656
Lysosome 600 | 600
Lytic vacuole 600 | 600
Endosomal part 554 | 554
Chromatin 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone H2A type 2-A HIST2H2AA3 Tbio Non-IDG -3.04065 999.3 88
Histone H2A type 2-C HIST2H2AC Tbio Non-IDG -3.03938 994.7 101
Histone H2B type 2-E HIST2H2BE Tbio Non-IDG -3.48425 2920.0 135
Zinc finger protein with KRAB and SCAN domains 7 ZKSCAN7 Tbio Transcription Factor -2.02912 100.6 54
Chromobox protein homolog 1 CBX1 Tbio Epigenetic -2.31837 203.1 260
Chromodomain-helicase-DNA-binding protein 5 CHD5 Tbio Epigenetic -1.19343 17.9 84
Chromobox protein homolog 5 CBX5 Tbio Epigenetic -1.90801 83.4 624
Histone-lysine N-methyltransferase, H3 lysine-79 specific DOT1L Tchem Epigenetic -2.29797 199.6 330
Histone-lysine N-methyltransferase KMT5B KMT5B Tbio Epigenetic -1.20275 14.3 158
M-phase phosphoprotein 8 MPHOSPH8 Tchem Epigenetic -1.16644 15.5 58