Development Level

Tbio 68 | 10,625
Tchem 30 | 1,890
Tclin 19 | 602
Tdark 3 | 7,003

IMPC Phenotype

preweaning lethality, complete... 4 | 633
decreased hemoglobin content 3 | 53
preweaning lethality, incomple... 3 | 260
abnormal retinal pigmentation 2 | 61
abnormal snout morphology 2 | 18
decreased body weight 2 | 174
decreased bone mineral content 2 | 157
decreased circulating insulin ... 2 | 75
decreased lean body mass 2 | 195
decreased mean corpuscular hem... 2 | 19
decreased mean corpuscular vol... 2 | 50
decreased monocyte cell number 2 | 28
decreased total body fat amoun... 2 | 186
increased circulating total pr... 2 | 20
abnormal behavior 1 | 226
abnormal bone structure 1 | 131
abnormal cornea morphology 1 | 24
abnormal cranium morphology 1 | 32
abnormal embryo size 1 | 112
abnormal epididymis morphology 1 | 31
abnormal forced expiratory flo... 1 | 1
abnormal forebrain development 1 | 18
abnormal heart morphology 1 | 51
abnormal hindbrain development 1 | 24
abnormal lumbar vertebrae morp... 1 | 6
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal retina morphology 1 | 100
abnormal skin condition 1 | 6
abnormal skin morphology 1 | 23
abnormal sleep behavior 1 | 63
abnormal spinal cord morpholog... 1 | 8
abnormal whole-body plethysmog... 1 | 4
absent heartbeat 1 | 6
altered righting response 1 | 1
corneal opacity 1 | 25
decreased Ly6C high monocyte n... 1 | 18
decreased T-helper cell number 1 | 4
decreased body length 1 | 108
decreased body temperature 1 | 2
decreased bone mineral density 1 | 126
decreased circulating alanine ... 1 | 53
decreased circulating alkaline... 1 | 41
decreased circulating aspartat... 1 | 27
decreased circulating calcium ... 1 | 33
decreased circulating chloride... 1 | 32
decreased circulating choleste... 1 | 85
decreased circulating creatini... 1 | 31
decreased circulating free fat... 1 | 39
decreased circulating iron lev... 1 | 25
decreased circulating triglyce... 1 | 83
decreased effector memory CD8-... 1 | 24
decreased eosinophil cell numb... 1 | 41
decreased hematocrit 1 | 25
decreased lactate dehydrogenas... 1 | 14
decreased lymphocyte cell numb... 1 | 9
decreased mean corpuscular hem... 1 | 34
decreased tidal volume 1 | 1
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
enlarged epididymis 1 | 27
enlarged lymph nodes 1 | 27
improved glucose tolerance 1 | 56
increased CD4-positive, CD25-p... 1 | 18
increased CD4-positive, alpha ... 1 | 15
increased KLRG1+ CD4 alpha bet... 1 | 5
increased NK cell number 1 | 19
increased T cell number 1 | 15
increased alpha-beta T cell nu... 1 | 9
increased blood urea nitrogen ... 1 | 44
increased body weight 1 | 42
increased circulating alkaline... 1 | 119
increased circulating iron lev... 1 | 25
increased circulating triglyce... 1 | 24
increased effector memory CD4-... 1 | 15
increased gamma-delta T cell n... 1 | 16
increased grip strength 1 | 83
increased hematocrit 1 | 36
increased lean body mass 1 | 107
increased leukocyte cell numbe... 1 | 37
increased lymphocyte cell numb... 1 | 9
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased mean platelet volume 1 | 19
increased monocyte cell number 1 | 27
increased neutrophil cell numb... 1 | 15
increased red blood cell distr... 1 | 21
increased rib number 1 | 41
increased total body fat amoun... 1 | 57
male infertility 1 | 62
premature death 1 | 5
prenatal lethality prior to he... 1 | 64
short snout 1 | 4
straub tail 1 | 26
tremors 1 | 34
vertebral transformation 1 | 12

Disease

Cancer 74 | 2,346
diabetes mellitus 70 | 1,663
Anemia 69 | 252
psoriasis 62 | 6,685
osteosarcoma 60 | 7,933
Kidney disease 57 | 397
ovarian cancer 53 | 8,491
Hypertension 49 | 293
Heart disease 45 | 279
Obesity 44 | 616
Coronary artery disease 43 | 240
Liver disease 43 | 219
Cerebrovascular disease 42 | 231
Atherosclerosis 41 | 275
lung cancer 40 | 4,473
glioblastoma 36 | 5,572
invasive ductal carcinoma 33 | 2,950
lung carcinoma 32 | 2,844
medulloblastoma, large-cell 32 | 6,234
ulcerative colitis 31 | 2,087
Hyperglycemia 30 | 120
Thrombocytopenia 29 | 105
lung adenocarcinoma 29 | 2,714
tuberculosis 29 | 1,563
Malaria 27 | 140
interstitial cystitis 27 | 2,299
Metabolic syndrome X 26 | 155
Diarrhea 25 | 155
Hypertensive disease 25 | 193
Rheumatoid Arthritis 25 | 1,170
Thalassemia 25 | 46
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 25 | 2,988
non-small cell lung cancer 25 | 2,798
breast carcinoma 23 | 1,614
intraductal papillary-mucinous neoplasm (IPMN) 23 | 3,289
Alzheimer's disease 22 | 644
Lung disease 22 | 136
malignant mesothelioma 22 | 3,163
pilocytic astrocytoma 22 | 3,086
Asthma 21 | 349
Lipid metabolism disorder 21 | 102
Fatty liver disease 20 | 86
Peripheral vascular disease 20 | 90
Prostatic Neoplasms 20 | 471
cystic fibrosis 20 | 1,670
pancreatic cancer 20 | 2,300
Arthritis 19 | 248
Breast cancer 19 | 3,098
Heart failure 19 | 80
Hepatitis C 19 | 90
Hyperinsulinism 19 | 63
atypical teratoid / rhabdoid tumor 19 | 4,369
ductal carcinoma in situ 19 | 1,745
Hypersensitivity reaction type II disease 18 | 235
Neuropathy 18 | 210
mucosa-associated lymphoid tissue lymphoma 18 | 480
pancreatic ductal adenocarcinoma liver metastasis 18 | 1,795
pediatric high grade glioma 18 | 2,712
Acute kidney injury 16 | 65
Brain disease 16 | 84
Carcinoma 16 | 2,147
Hepatitis B 16 | 103
Hypoglycemia 16 | 81
Hypothyroidism 16 | 89
Inflammation 16 | 109
Leukopenia 16 | 42
Myocardial Infarction 16 | 126
Pancreatitis 16 | 97
Pneumonia 16 | 133
sarcoidosis 16 | 368
Cholestasis 15 | 93
Diabetes Mellitus, Non-Insulin-Dependent 15 | 161
Diabetic Retinopathy 15 | 53
Inflammatory bowel disease 15 | 142
Liver Cirrhosis 15 | 101
Polycystic Ovary Syndrome 15 | 334
Vasculitis 15 | 64
oligodendroglioma 15 | 2,849
posterior fossa group A ependymoma 15 | 1,511
primitive neuroectodermal tumor 15 | 3,031
Drug-Induced Liver Injury 14 | 118
Liver Cirrhosis, Experimental 14 | 108
Mammary Neoplasms 14 | 410
Osteoporosis 14 | 259
adult high grade glioma 14 | 2,148
Acquired immunodeficiency syndrome 13 | 164
Allergic hypersensitivity disease 13 | 123
Diabetes Mellitus, Experimental 13 | 106
Kidney Failure, Chronic 13 | 45
Myocardial Ischemia 13 | 169
Sickle Cell Anemia 13 | 54
acute quadriplegic myopathy 13 | 1,157
ependymoma 13 | 2,514
group 3 medulloblastoma 13 | 2,254
periodontitis 13 | 269
pituitary cancer 13 | 1,972
subependymal giant cell astrocytoma 13 | 2,287
Atopic dermatitis 12 | 944
Vascular disease 12 | 281

Tissue

Digestive Tract 117 | 18,472
Endocrine System 117 | 18,511
Female tissues 117 | 18,646
Nervous System 117 | 18,560
Liver and Pancreas 116 | 18,135
Urinary Tract 116 | 18,443
Blood and immune system 115 | 17,994
Skin and soft tissues 115 | 18,114
Cardiovascular System 114 | 17,957
Male tissues 112 | 17,968
Respiratory system 110 | 17,483

Target Family

Non-IDG 74 | 11,969
Enzyme 34 | 4,146
Transcription Factor 4 | 1,400
Kinase 3 | 634
Transporter 3 | 473
GPCR 1 | 408
Ion Channel 1 | 341

Compartment GO Term

Hemoglobin complex 120 | 120
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Hemoglobin subunit zeta HBZ Tbio Non-IDG -2.36868 235.4 158
CD40 ligand CD40LG Tchem Non-IDG -4.56976 36580.5 1095
Alpha-1-antitrypsin SERPINA1 Tbio Non-IDG -3.73976 5495.0 809
Maltase-glucoamylase, intestinal MGAM Tclin Enzyme -4.50018 27956.4 30
Cystatin-C CST3 Tbio Non-IDG -3.48935 3020.7 756
Putative keratin-87 protein KRT87P Tdark Non-IDG -1.97445 161.6 0
Low affinity sodium-glucose cotransporter SLC5A4 Tchem Transporter -2.67747 440.8 60
Dipeptidyl peptidase 4 DPP4 Tclin Enzyme -3.60140 4091.0 900
Alpha-hemoglobin-stabilizing protein AHSP Tbio Non-IDG -1.99625 96.5 108
Oxytocin-neurophysin 1 OXT Tbio Non-IDG -4.17412 14677.4 133